Distinct domains within Mash1 and Math1 are required for function in neuronal differentiation versus neuronal cell-type...
The neural bHLH factors belong to a much larger family of transcription factors that are essential for diverse processes such ... M) Diagram of different populations of progenitors (dP1-dP6 defined by bHLH expression) and interneurons (dI1-dI6 defined by ... Of the Class II bHLH factors, only the neural bHLH factors, Mash1 and Math1 but not the non-neural bHLH factor MyoD, induced ... a class II bHLH factor important in hematopoiesis, a LIM only factor (LMO) and Ldb factors were seen to form a complex with ...http://dev.biologists.org/content/131/6/1319
Induction of S phase by G1 regulatory factors.
0/Transcription Factor DP1; 0/Transcription Factors; 0/Tumor Suppressor Proteins; 147604-94-2/Cyclin-Dependent Kinase Inhibitor ... E2F Transcription Factors. G1 Phase*. Humans. Microtubule-Associated Proteins / metabolism. Protein-Serine-Threonine Kinases / ... Another G1 cyclin, cyclin E, and a transcription factor E2F are situated the furthest downstream of known G1 regulators and ... 0/E2F Transcription Factors; 0/Microtubule-Associated Proteins; 0/Proto-Oncogene Proteins; 0/Retinoblastoma-Binding Protein 1; ...http://www.biomedsearch.com/nih/Induction-S-phase-by-G1/10577389.html
Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity | Diabetes
... transcription factor Dp-1. (A high-quality color representation of this figure is available in the online issue.) ... SP1, Sp1 transcription factor; NFATC3, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; BHLH, basic ... MicroRNA 155 modulates megakaryopoiesis at progenitor and precursor level by targeting Ets-1 and Meis1 transcription factors. ... The miRNAs may act directly on the target genes or indirectly by first regulating transcription factors (TFs), which, in turn, ...http://diabetes.diabetesjournals.org/content/61/8/1986.full
Microarray analysis of iron deficiency chlorosis in near-isogenic soybean lines | BMC Genomics | Full Text
These transcription factors are one of the largest families of transcription factors and can be induced by abiotic stresses [39 ... He XJ, Mu RL, Cao WH, Zhang ZG, Zhang JS, Chen SY: AtNAC2, a transcription factor downstream of ethylene and auxin signaling ... These zinc finger proteins may be acting as transcription factors in the regulation of the ubiquitin pathway in soybean, or ... A Guard-Cell-Specific MYB Transcription Factor Regulates Stomatal Movements and Plant Drought Tolerance. Current Biology. 2005 ...https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-8-476
CUL4A overexpression as an independent adverse prognosticator in intrahepatic cholangiocarcinoma | BMC Cancer | Full Text
Thus, it may prove to be a powerful prognostic factor and a potential therapeutic target. ... Transcription factor Dp-1. TSC2: Tuberous sclerosis 2. UICC: Union for International Cancer Control ... reported that a tumor with size ,5 cm was a risk factor associated with tumor recurrence and poorer iCCA patient survival [17, ... CUL4A could be a factor influencing EMT. Evidence for this was provided by the study of Wang et al. who reported that CUL4A ...https://bmccancer.biomedcentral.com/articles/10.1186/s12885-017-3389-z
RAS Pathway v2.0 - National Cancer Institute
transcription factor Dp-1. DP1, DRTF1, Dp-1. TFDP2. transcription factor Dp-2 (E2F dimerization partner 2). DP2. ... nuclear factor, erythroid 2-like 2. NRF2. NFKB1. nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. EBP-1, ... fibroblast growth factor receptor 3. CH, CD333, CEK2, HSFGFR3EX, JTK4. FGFR4. fibroblast growth factor receptor 4. CD334, JTK2 ... epidermal growth factor receptor. ERBB, ERBB1, HER1, PIG61, mENA. EIF4EBP1. eukaryotic translation initiation factor 4E-binding ...https://www.cancer.gov/research/key-initiatives/ras/ras-central/blog/2015/ras-pathway-v2
Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely...
transcription factor Dp-1 Transcription factor that heterodimerizes with E2F proteins to enhance their DNA-binding activity and ... Chan JA, Olvera M, Lai R, Naing W, Rezk SA, Brynes RK: Immunohistochemical expression of the transcription factor DP-1 and its ... coagulation factor X. Coagulation factor. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of ... Transcription factor involved in the regulation of embryonic development and in the determination of the cell fate ...https://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr2456
transcription factor Dp-1. THOP1. 7064. THOP1. thimet oligopeptidase 1. TIAL1. 7073. TIAL1. TIA1 cytotoxic granule-associated ... TFT: transcription factor targets C4: computational gene sets CGN: cancer gene neighborhoods CM: cancer modules C5: GO gene ... transcription elongation factor A (SII.... TCEB1. 6921. TCEB1. transcription elongation factor B (SII.... ...http://software.broadinstitute.org/gsea/msigdb/cards/MORF_RAD23A.html
TFDP1 - Wikipedia
Transcription factor Dp-1 is a protein that in humans is encoded by the TFDP1 gene. The E2F transcription factor family (see ... "Entrez Gene: TFDP1 transcription factor Dp-1". Sardet C, Vidal M, Cobrinik D, Geng Y, Onufryk C, Chen A, Weinberg RA (Mar 1995 ... "Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation". Genes Dev. 7 (10): 1850- ... "Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation". Genes Dev. 7 (10): 1850- ...https://en.wikipedia.org/wiki/TFDP1
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev 1993; 7: 1850- ... The E2F and MYC transcription factors are critical regulators of cell proliferation and contribute to the development of human ... Importantly, the association of ATAD2 with other oncogenic transcription factors, such the androgen and estrogen receptors ( 23 ... sequence-specific transcription factor ( 6) interacting both with the SWI/SNF chromatin remodeling complexes ( 7) and with the ...http://cancerres.aacrjournals.org/content/69/21/8491
Multiple displacement amplification for complex mixtures of DNA fragments | BMC Genomics | Full Text
To confirm its usefulness in research, DP1 bound chromatin was isolated through ChIP and presence of DHFR promoter was detected ... We used binding of DHFR promoter with transcription factor DP1 as a model in our experiments. NIH3T3 cells were transiently ... a) DP1 complex with DHFR and GAPDH promoters. NIH 3T3 cells were transiently transfected with pBBHN.DP1 vector and subjected to ... 5a, the DP1 bound chromatin contains significant amount of DHFR promoter, compared to the control chromatin immunoprecipitate, ...https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-9-415
STRUCTURE OF THE RB C-TERMINAL DOMAIN BOUND TO AN E2F1-DP1 TITLE 2 HETERODIMER COMPND 2 MOLECULE: TRANSCRIPTION FACTOR DP-1; ... 2aze_A_str_2 (A: 262-295) TRANSCRIPTION FACTOR DP-1 IIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHD Coordinates. ... 2aze_A_seq_2 (A: 262-295) TRANSCRIPTION FACTOR DP-1 IIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHD Coordinates. ... 2aze_A_cm_1 (* A:198-261 A:296-346 B:201-256) TRANSCRIPTION FACTOR DP-1 ...http://prodata.swmed.edu/multidom/files/2aze_A.shtml
Arabidopsis E2F1 binds a sequence present in the promoter of S-phase-regulated gene AtCDC6 and is a member of a multigene...
Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F ... Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation ... Mammalian E2F transcription factors are composed of E2F and DP subunits, and with their negative regulators, Rb- ... The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated ...https://www.deepdyve.com/lp/springer_journal/arabidopsis-e2f1-binds-a-sequence-present-in-the-promoter-of-s-phase-0tgO10giyx
Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wld s ) | Genome...
Transcription factor Dp-1. TFDP1 NM_007111. G09. -22.50. 1.04. Regulation. NAD, nicotinamide adenine dinucleotide; SD, standard ... Pttg1 is currently the only known physiological substrate for the E4 ubiquitination factor Ube4b , which is one of the ... The ability to control cell cycle pathways is therefore a critical factor in stopping neurons entering a vulnerable state, ... The photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod ...https://genomebiology.biomedcentral.com/articles/10.1186/gb-2008-9-6-r101
An Introduction to Molecular Biology/Cell Cycle - Wikibooks, open books for an open world
... the Rb-HDAC repressor complex binds to the E2F-DP1 transcription factors, therefore inhibiting the downstream transcription. ... TGFb inhibits the transcription of Cdc25A, a phosphatase that activates the cell cycle kinases, and growth factor withdrawal ... the transcription factors SBF and MBF, and the transcriptional inhibitor Whi5. Cln3 interacts with Cdk1 to initiate the ... promoting the expression of transcription factors that in turn promote the expression of S cyclins and of enzymes required for ...https://en.wikibooks.org/wiki/An_Introduction_to_Molecular_Biology/Cell_Cycle
E2F1 - Wikipedia
"Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation". Genes Dev. 7 (10): 1850- ... Transcription factor E2F1 is a protein that in humans is encoded by the E2F1 gene. The protein encoded by this gene is a member ... "Entrez Gene: E2F1 E2F transcription factor 1". Suzuki M, Okuyama S, Okamoto S, Shirasuna K, Nakajima T, Hachiya T, Nojima H, ... Strachan GD, Jordan-Sciutto KL, Rallapalli R, Tuan RS, Hall DJ (February 2003). "The E2F-1 transcription factor is negatively ...https://en.wikipedia.org/wiki/E2F1
Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics...
Transcription factor DP1. Partner of E2F transcription factors. Tfdp2 Transcription factor DP1 ... translocates to the nucleus and associates with transcription factors of the T-cell factor/lymphoid enhancer factor (TCF/LEF) ... miRNAs and transcription factors motifs for genes up-regulated in the Frzb -/- mice ... The responsive elements for TCF/LEF but also other transcription factors, related to WNT signaling, in the Col3 and Col5 ...https://arthritis-research.biomedcentral.com/articles/10.1186/ar3695
Endocrine Immune Interactions in the Host-Parasite Relationship: Steroid Hormones as Immune Regulators in Parasite Infections ...
Dissanayake S (2000) Upregulation of a raf kinase and a DP-1 family transcription factor in epidermal growth factor (EGF) ... Karpuzoglu E, Phillips RA, Gogal RM Jr, Ansar Ahmed S (2007) IFN-gamma-inducing transcription factor, T-bet is upregulated by ... 2004) Differential expression of AP-1 transcription factor genes c-fos and c-jun in the helminth parasites Taenia crassiceps ... Some hormone signals are involved in the expression of transcription factors in the cell nucleus (genomic effects). These ...https://www.omicsonline.org/open-access/endocrine-immune-interactions-in-the-hostparasite-relationship-steroidhormones-as-immune-regulators-in-parasite-infections-2157-7536-1000165.php?aid=66321
TFDP1 Full-Length MS Protein Standard - Creative Proteomics
This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA- ... binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to ... transcription factor Dp-1. Symbol. TFDP1. Synonyms. Dp-1; DP1; DRTF1. Accession. NM_007111. ... This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA- ...https://www.creative-proteomics.com/product/detail-cpfl303986_1910.htm
IMP: Integrative Multi-species Prediction
transcription factor Dp-1. 0.015. GSR. glutathione reductase. 0.015. NNT. nicotinamide nucleotide transhydrogenase. 0.015. ... pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2. 0.111. ... pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha. 0.026. ...http://imp.princeton.edu/predictions/process/human-context-global/10552/?gene=2568
IMP: Integrative Multi-species Prediction
transcription factor Dp-1. 0.052. MDC1. mediator of DNA-damage checkpoint 1. 0.051. ... signal transducer and activator of transcription 3 (acute-phase response factor). 0.085. ... TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. 0.015. ... nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein. 0.019. ...http://imp.princeton.edu/predictions/process/human-context-global/15356/?gene=8371
Furthermore, phosphorylation of retinoblastoma protein (Rb) was activated which released the transcription factor E2F and DP-1 ...http://cancerres.aacrjournals.org/content/68/9_Supplement/2238
Osteoprotegerin secreted by inflammatory and invasive breast cancer cells induces aneuploidy, cell proliferation and...
Gene copy numbers for oncogenic pathway regulators such AKT1, Aurora-A Kinase (AURKA or IAK-1), epidermal growth factor ... Bub1 and BubR1 probably through the receptor activator of nuclear factor kappa-B ligand (RANKL) and syndecan-1 receptors via ... transcription factor Dp-1; TFDP1), cell cycle (Aurora A kinase, BCL2L1, CCND1, CDK4, cyclin-dependent kinase inhibitor 2A; ... OPG, also known as osteoclastogenesis inhibitory factor or tumor necrosis factor receptor superfamily member 11B (TNFRSF11B), ...https://bmccancer.biomedcentral.com/articles/10.1186/s12885-015-1837-1
Similar articles for PubMed (Select 8446173) - PubMed - NCBI
DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for ... Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. ... E2F site activates transcription in fission yeast Schizosaccharomyces pombe and binds to a 30-kDa transcription factor. ... A new component of the transcription factor DRTF1/E2F.. Girling R, Partridge JF, Bandara LR, Burden N, Totty NF, Hsuan JJ, La ...https://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=8446173
Involvement of Retinoblastoma Family Members and E2F/DP Complexes in the Death of Neurons Evoked by DNA Damage | Journal of...
1993) Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J 12:4317- ... DN DP1 virus + UV (C), (Δ1-126) DN DP1 control virus + UV (D), or (Δ1-126) DN DP1 virus alone (E). The photos were taken 2 d ... survival with DN DP1 expression vs 50% without). Expression of a mutant of DP1 [(Δ233-272) DP1] bearing the E2F-binding domain ... DP1, and (Δ233-272) DP1. Control nonexpressing vectors of each DP1 construct were generated by eliminating the initiating codon ...http://www.jneurosci.org/content/20/9/3104?ijkey=6f6be308824c5b391489fcba8818355da294edc5&keytype2=tf_ipsecsha