Activator protein Transcription factor Hess J, Angel P, Schorpp-Kistner M (December 2004). "AP-1 subunits: quarrel and harmony ... Lee W, Mitchell P, Tjian R (June 1987). "Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements". ... activation of a predetermined enhancer landscape controlled by the pioneer transcription factor AP-1", which "defines the ... Ahn JD, Morishita R, Kaneda Y, Lee KU, Park JY, Jeon YJ, Song HS, Lee IK (June 2001). "Transcription factor decoy for activator ...

... is the AP-1 transcription factor required for Ras-induced lung cancer. ... The AP-1 transcription factor c-Jun is required for Ras-driven tumorigenesis in many tissues and is considered as a classical ...

Transcription Factor AP-1 / metabolism Substances * Carrier Proteins * Intracellular Signaling Peptides and Proteins ... NEPH1 triggers AP-1 activation similarly to nephrin but requires the presence of Tec family kinases for efficient ... Lorenz Sellin 1 , Tobias B Huber, Peter Gerke, Ivo Quack, Hermann Pavenstädt, Gerd Walz ... 1 Department of Internal Medicine, Division of Nephrology, University Hospital Freiburg, Germany. ...

Transcription Factor AP-1 / antagonists & inhibitors * Transcription, Genetic / drug effects* * Transcriptional Activation / ... RA, but not these dissociating retinoids, induced transcription of an interleukin-6 promoter-based reporter gene transiently ... J Y Chen 1 , S Penco, J Ostrowski, P Balaguer, M Pons, J E Starrett, P Reczek, P Chambon, H Gronemeyer ... 1 Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France. ...

Mouse JDP2 cDNA has also been cloned by yeast two-hybrid screening, using activating transcription factor-2 (ATF-2) as the bait ... Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to ... Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to ... Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappaB and c-Jun N-terminal kinase. J. ...

... and nuclear transcription factor erythroid 2p45-related factor (Nrf2)) related to antioxidant defence and survival and ... present study was to investigate the time-dependent regulation by epicatechin on the activity of the main transcription factors ... Time-dependent activation of the AP-1 pathway, in concert with enhanced c-Jun nuclear levels and induction of Nrf2 ... data suggest that the epicatechin-induced survival effect occurs by the induction of redox-sensitive transcription factors ...

The AP-1 transcription factor JUN is promptly induced in SCs upon nerve injury and potently mediates this injury-induced SC ... The AP-1 transcription factor JUN is promptly induced in SCs upon nerve injury and potently mediates this injury-induced SC ... The AP-1 transcription factor JUN is promptly induced in SCs upon nerve injury and potently mediates this injury-induced SC ... The AP-1 transcription factor JUN is promptly induced in SCs upon nerve injury and potently mediates this injury-induced SC ...

The early response gene proteins, Fos and Jun family, are components of the transcription factor AP-1 that, depending on its ...

Transcription Factor AP-1. Li Q, Dashwood W-M, Zhong X, Al-Fageeh M, Dashwood RH. 2004. Cloning of the rat beta-catenin gene ( ... Transcription Factors. Li Q, Dashwood W-M, Zhong X, Al-Fageeh M, Dashwood RH. 2004. Cloning of the rat beta-catenin gene ( ... Transcription Initiation Site. Li Q, Dashwood W-M, Zhong X, Al-Fageeh M, Dashwood RH. 2004. Cloning of the rat beta-catenin ... Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f] ...

... the identification of cis-regulatory sites in previously unexplored regions of the genome and the cooperating transcription ... Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer. J. Biol. Chem. 269, 16433 ... Figure 4: Identification of enriched motifs within the estrogen receptor binding sites and validation of transcription factor ... Figure 5: Involvement of cooperating transcription factors at estrogen receptor binding sites.. ...

nalyot, a mutation of the Drosophila myb-related Adf1 transcription factor, disrupts synapse formation and olfactory memory. ... AP-1 functions upstream of CREB to control synaptic plasticity in Drosophila. Nature. 2002 Apr 25;416(6883):870-4. Narayanan R ... Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons. BMC Neurosci. 2005 Jun 2;6:39. Narayanan R, ... Activity-dependent regulation of transcription during development of synapses. Int Rev Neurobiol. 2006;75:287-305. Kumar V, ...

The gene transcription factor cyclic AMP-responsive element binding protein: role in positive and negative affective states of ... FOSB; FosB proto-oncogene, AP-1 transcription factor subunit [KO:K09029]. 84152 PPP1R1B; protein phosphatase 1 regulatory ... GRB2; growth factor receptor bound protein 2 [KO:K04364]. 6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1 [KO: ... BDNF; brain derived neurotrophic factor [KO:K04355]. 4915 NTRK2; neurotrophic receptor tyrosine kinase 2 [KO:K04360] [EC:2.7. ...

ATF4; activating transcription factor 4 [KO:K04374]. 10488 CREB3; cAMP responsive element binding protein 3 [KO:K09048]. ... FOS; Fos proto-oncogene, AP-1 transcription factor subunit [KO:K04379]. 1139 CHRNA7; cholinergic receptor nicotinic alpha 7 ... ITPR3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]. 5578 PRKCA; protein kinase C alpha [KO:K02677] [EC:2.7.11.13] ... AKT1; AKT serine/threonine kinase 1 [KO:K04456] [EC:2.7.11.1]. 208 AKT2; AKT serine/threonine kinase 2 [KO:K04456] [EC:2.7.11.1 ...

Filipe Pereiras lab contains the insert Fos proto-oncogene, AP-1 transcription factor subunit and is published in Cell Rep. ... Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming. Gomes AM, Kurochkin I, Chang B, Daniel M, Law K, ... FOS (a.k.a. AP-1, C-FOS, p55) * Promoter TRE-mCMV ... Fos proto-oncogene, AP-1 transcription factor subunit * Species ...

Fos proto-oncogene, AP-1 transcription factor subunit. multiple interactions. EXP. [Nifedipine co-treated with omega-Conotoxin ... NCBI chr 1:95,080,960...95,095,165 Ensembl chr 1:95,080,960...95,095,160 G. Sct. secretin. multiple interactions. EXP. omega- ... Ensembl chr 1:196,382,856...196,383,658 G. Snca. synuclein alpha. multiple interactions. EXP. omega-Conotoxin GVIA inhibits the ... tachykinin, precursor 1. multiple interactions. EXP. omega-Conotoxin GVIA inhibits the reaction [Potassium results in increased ...

Jun and Fos activate other transcription factors, such as activating transcription factor 2 (ATF 2), cAMP response element- ... PDCD4 inhibits growth promotion through the suppression of the transactivation of the AP-1 promoter via c-Jun [141] and through ... As a consequence, this enhanced the accessibility of DNA promoters to transcription factors, increasing the synthesis of the ... or transcription factors affecting transcript production and transport. In this way, lncRNAs can act as oncogenes or tumor ...

... they can regulate gene expression by inhibiting the activity of other transcription factors, such as AP-1. The AP-1 ... and the expression of transcription factors and toll receptors involved in immunomodulation (Wolf, 2002). These various ... Gene transcription after conversion to all-trans retinoic acid.. Comedolysis.. Epidermal thickening, dermal regeneration, ... Gene transcription affects growth and differentiation of cells in the skin.. Normalizes follicular epithelial differentiation. ...

... regulation the expressions of redox-sensitive transcription factors, including NF-κB, MAPKs, AP-1, HIF, PI3K/Akt; (4) ... The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic ... SREBP-1c is a transcription factor associated with the promoter region of a number of genes related to fat formation. SREBP-1c ... Nrf2 is an important transcription factor that regulates the balance of redox in cells. Under normal physiological conditions, ...

Moll T, Czyz M, Holzmuller H. Regulation of the tissue factor promoter in endothelial cells. Binding of NFκB-, AP-1-, and Sp1- ... Czimmerer Z, Daniel B, Horvath A. The transcription factor STAT6 mediates direct repression of inflammatory enhancers and lmits ... Figure 6.Staining of tissue factor-positive macrophages in sections of colon carcinoma. (A) Tissue factor (TF) (red) and CD206 ... Figure 2.Tissue factor-specific mRNA induction by alternative polarization. (A) Tissue factor (TF) mRNA levels at the indicated ...

Herbert, D., Hung, L. Y., Sen, D., Oniskey, T., Kim, C., Krummel, M.: Trefoil factor 2 maintains and restores pulmonary ... Myeloid expression of the AP-1 transcription factor JUNB modulates outcomes of type 1 and type 2 parasitic infections. Parasite ... Macrophage-Dependent Regeneration of Pulmonary Epithelia Requires Trefoil Factor 2 for Wnt Expression. J Immunol 196, 2016.. ... Mucosal Immunol 9(1): 240-253, 2016.. Hung, L. Y., Sen, D., Oniskey, T. K., Nieves, W., Urisman, A., Krummel, M. F., Herbert, D ...

The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 ... AP-1 Transcription Factors Mediate BDNF-Positive Feedback Loop in Cortical Neurons. Authors: Tuvikene Et al.. J Neurosci 2016; ... Regulation of nuclear factor κB in the hippocampus by group I metabotropic glutamate receptors. Authors: O'Riordan Et al.. ... Retinal injury, growth factors, and cytokines converge on β-catenin and pStat3 signaling to stimulate retina regeneration. ...

... such as transforming growth factor-beta. Other research has found overexpression of JunB, [12] part of the AP-1 transcription ... Kontos AP, Kerr HA, Malick F, Fivenson DP, Lim HW, Wong HK. 308-nm excimer laser for the treatment of lymphomatoid papulosis ... 15, 16, 17] Unfortunately, no clinical or histologic factors analyzed to date are predictive of worse outcomes in persons with ... 18] Alterations in transforming growth factor-beta signaling are hypothesized to play a role in the progression of lymphomatoid ...

AP-1 Antibodies. AP1 Antibodies. c-Jun Antibodies. c-jun Antibodies. CG2275 Antibodies. cJun Antibodies. d-JRA Antibodies. D- ... "IP-10 Promotes Blood-Brain Barrier Damage by Inducing Tumor Necrosis Factor Alpha Production in Japanese Encephalitis." in: ... Jun proto-oncogene, AP-1 transcription factor subunit (Jun) Antibodies. jun proto-oncogene S homeolog (jun.S) Antibodies. Jun ... Jun proto-oncogene, AP-1 transcription factor subunit (JUN) Antibodies. ...

While many factors are involved in the etiology of cancer, it has been clearly established that diet significantly impacts ... activation of inflammatory transcription factors nuclear factor-kappa B and signal transducer and activator of transcription 1 ... Uzzo, R.G.; Crispen, P.L.; Golovine, K.; Makhov, P.; Horwitz, E.M.; Kolenko, V.M. Diverse effects of zinc on NF-kappaB and AP-1 ... ER-α and β are the receptors for estrogen and function as ligand-dependent transcription factors, with the β receptor being ...

Changes in Transcription Factors Binding the AP-1 Site Zheng Guo, Xinyu Du and Lorraine Iacovitti ... Changes in Transcription Factors Binding the AP-1 Site Zheng Guo, Xinyu Du and Lorraine Iacovitti ... Changes in Transcription Factors Binding the AP-1 Site Zheng Guo, Xinyu Du and Lorraine Iacovitti ... Autocrine Hepatocyte Growth Factor Provides a Local Mechanism for Promoting Axonal Growth Xiu-Ming Yang, Jean G. Toma, Shernaz ...

B and AP-1, the ellagic acid treatment led to reduced BALF levels of IL-6 and increased levels of IL-10. In addition, ... Dexamethasone (1 mg/kg; subcutaneous route) was used as a positive control. In both preventive and therapeutic ... dexamethasone treatment reduced IL-1,i,β,/i,. Together, these findings identify ellagic acid as a potential therapeutic ... M. L. Handel, "Transcription factors AP-1 and NF-κB: where steroids meet the gold standard of anti-rheumatic drugs," ...

Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor. Yan, C., Lee, L.H., Davis, L.I. EMBO J. ( ... Defects in mRNA 3-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: ... Overexpression of Bud5p can suppress mutations in the Gsp1p guanine nucleotide exchange factor Prp20p in Saccharomyces ... In yeast Rna1p is the GTPase activating protein for Ran (RanGAP) and Prp20p is the Ran GDP/GTP exchange factor (GEF) [11]. ...

The second gene, JUN, is a transcription factor and component of the AP-1 transcription complex that plays a key in role in ... Migheli, A., Piva, R., Atzori, C., Troost, D. & Schiffer, D. c-Jun, JNK/SAPK kinases and transcription factor NF-kappa B are ... Besides the three key signaling components mentioned above (ERN1, EIF2AK3, ATF6), we selected transcription factors X-Box ... activating transcription factor 6). The main role of the UPR is to ensure homeostasis by increasing protein folding capacity ...

Vascular Endothelial Growth Factor A. *Tumor Cells, Cultured. *Transcription Factors. *Transcription Factor AP-1 ... CONCLUSION: These results suggest that overexpression of TrkB and activation of mitogen-activated protein kinase and AP-1, ... Furthermore, interleukin 8 and vascular endothelial growth factor were more strongly expressed in Colo357L3.6pl than Colo357FG ... which may in turn induce the expression of vascular endothelial growth factor and interleukin 8, may mediate the cardinal ...

The AP-1 transcription factor mediates CXCL1-induced promotion of IL-6 expression in OASFs and RASFs. AP-1 plays a critical ... Pretreatment with AP-1 inhibitors (tanshinone IIA and curcumin) blocked IL-6 expression in response to CXCL1 treatment in OASFs ... 5A and 5B). When AP-1 activation was examined by phosphorylation of c-Jun, the results revealed that CXCL1 promoted c-Jun ... As shown in figure 5E, the nucleus translocation of AP-1 was increased in the CXCL1-treated cells, however, pretreatment with ...