Transcription Factor RelA - Semantic Scholar
Transcription Factor RelA. Known as: p65, Transcription Factor, v-Rel Reticuloendotheliosis Viral Oncogene Homolog A, NF-kappa ... Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 ... MUC1-C oncoprotein functions as a direct activator of the nuclear factor-kappaB p65 transcription factor. ... Single binding sites for transcription factors NF-IL6 and NF-kappa B are present in the promoter of the interleukin (IL) 6 gene ...https://www.semanticscholar.org/topic/Transcription-Factor-RelA/27894
DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide. - Semantic Scholar
The sequence and biochemical properties of the product of the cloned cDNA for the p65 subunit of nuclear factor kappa B (NF- ... IkB kinase b (IKKb/IKK2/IKBKB)-A key molecule in signaling to the transcription factor NF-kB. *Johannes A. Schmid, Andreas ... Fusion of ZMYND8 and RELA Genes in Acute Erythroid Leukemia. *Ioannis Panagopoulos, Francesca Micci, +6 authors Sverre Heim ... MiR-30a targets IL-1α and regulates islet functions as an inflammation buffer and response factor. *Xin Jiang, Chenke Xu, +5 ...https://www.semanticscholar.org/paper/DNA-binding-and-I-kappa-B-inhibition-of-the-cloned-Nolan-Ghosh/237175e94427e7b61052a7c8233638349d42b3f0
Tumor necrosis factor alpha inhibits collagen gene transcription and collagen synthesis in cultured human fibroblasts. -...
... and had no effects on alpha tubulin gene transcription. Thus, TNF alpha decreases collagen gene transcription, collagen mRNA ... The effects of recombinant human tumor necrosis factor alpha (TNF alpha) on collagen production and gene expression in cultured ... AGE-RAGE signal generates a specific NF-κB RelA "barcode" that directs collagen I expression. *Yunqian Peng, Ji-Min Kim, +4 ... Tumor necrosis factor alpha inhibits collagen gene transcription and collagen synthesis in cultured human fibroblasts.. @ ...https://www.semanticscholar.org/paper/Tumor-necrosis-factor-alpha-inhibits-collagen-gene-Sol%C3%ADs-Herruzo-Brenner/fa94af61b208f66e246c810563369ded87df201e
Transcriptional control of the development and function of Vα14i NKT cells. - Semantic Scholar
This review will describe our current understanding of the unique ways whereby transcription factors control the development ... A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes.. *Mala Dutta, ... Rel/NF-kappaB family member RelA regulates NK1.1- to NK1.1+ transition as well as IL-15-induced expansion of NKT cells.. * ... Distinct roles in NKT cell maturation and function for the different transcription factors in the classical NF-κB pathway.. * ...https://www.semanticscholar.org/paper/Transcriptional-control-of-the-development-and-of-Engel-Kronenberg/1813d7833f7f0321ed89b43f701e9eba8aaa804a
TNFα reverse signaling promotes sympathetic axon growth and target innervation - Semantic Scholar
Reverse signaling via members of the tumor necrosis factor (TNF) superfamily controls multiple aspects of immune function. Here ... factor kappa B signaling either stimulates or inhibits neurite growth depending on the phosphorylation status of p65/RelA.. * ... a link to structural plasticity of the nucleus and gene transcription regulation.. *J. Simon Wiegert, Hilmar Bading ... Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction.. *Keigan M. Park, William J. Bowers ...https://www.semanticscholar.org/paper/TNF%CE%B1-reverse-signaling-promotes-sympathetic-axon-Kisiswa-Os%C3%B3rio/90148c48208590ebd6bf64e7d1bce1746160ad43
A cell line model for the differentiation of human dendritic cells. - Semantic Scholar
... transcription factors of the NF-kappaB/Rel family essential for differentiation and maturation of DCs, as well as upregulation ... To further define the cells as DCs, cytosolic induction and upregulation of RelB and RelA (p65), ...https://www.semanticscholar.org/paper/A-cell-line-model-for-the-differentiation-of-human-Berges-Naujokat/ff22acee7c0310e6f44c6f698292f2862757991f
Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity. - Semantic Scholar
Activation of NF-κB Pathway in Hematopoietic Stem Cells Causes Loss of Quiescence and Deregulated Transcription Factor Networks ... Deletion of the NF-κB subunit p65/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function.. ... Hepatic Upregulation of Tumor Necrosis Factor Alpha and Activation of Nuclear Factor Kappa B Following Methyl Methacrylate ... Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors. *Cornelis J.H ...https://www.semanticscholar.org/paper/Positive-feedback-between-NF-%CE%BAB-and-TNF-%CE%B1-promotes-Kagoya-Yoshimi/98af6b25807f7738234954d1970f69abfbb28db0
Cyclic Di-GMP receptor PlzA controls virulence gene expression through RpoS in Borrelia burgdorferi. - Semantic Scholar
Correction: The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global ... Phosphoenolpyruvate Phosphotransferase System Components Modulate Gene Transcription and Virulence of Borrelia burgdorferi.. * ... Borrelia host adaptation Regulator (BadR) regulates rpoS to modulate host adaptation and virulence factors in Borrelia ...https://www.semanticscholar.org/paper/Cyclic-Di-GMP-receptor-PlzA-controls-virulence-gene-He-Zhang/bc80eedad28560d32266c6370553353aaf2d24bd
Effect of relA function on the replication of plasmid pBR322 in Escherichia coli - Semantic Scholar
... were measured in an isogenic relA + /relA pair of E. coli strains during exponential growth, or following amino acid starvation ... a protein which is synthesized during amino acid deprivation or treatment with low concentrations of chloramphenicol in relA ... Is tRNA only a translation factor or also a regulator of other processes?. *Grzegorz Węgrzyn, Alicja Węgrzyn ... Inhibition of transcription of the tryptophan operon in Escherichia coli by a block in initiation of translation.. *Fumio ...https://www.semanticscholar.org/paper/Effect-of-relA-function-on-the-replication-of-in-Lin-Chao-Bremer/19faeeb4ba44ff66bf6efc06312a19c912dcb718
In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation...
In particular, both elements were found to be required for inhibition of PEPCK transcription during sepsis, thereby mediating ... Predisposing factors for hypoglycemia in the intensive care unit.. Titia M Vriesendorp, Susanne van Santen, +4 authors Joost B ... Coactivator function of RIP140 for NFkappaB/RelA-dependent cytokine gene expression.. Inka Zschiedrich, Ulrike Hardeland, +12 ... Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha. ...https://www.semanticscholar.org/paper/In-vivo-phosphoenolpyruvate-carboxykinase-promoter-Chichelnitskiy-Vegiopoulos/d8ec70eb9193373626581698aeb146bb0a72192c
The quormone degradation system of Agrobacterium tumefaciens is regulated by starvation signal and stress alarmone (p)ppGpp. -...
Transposon mutagenesis of strain A6(attKLM::lacZ) led to identification of the relA gene, which encodes the stress alarmone (p) ... Tn5 knock-out of relA abolished the stationary phase-dependent expression of attM. We concluded that the A. tumefaciens ... AttJ, the other member of the signal degradation system, is an IclR-like negative transcriptional factor, which tightly ...https://www.semanticscholar.org/paper/The-quormone-degradation-system-of-Agrobacterium-is-Zhang-Wang/498053cc1ea25c169937d7dd581a054f2d7d7b54