Galectin-1 promotes tumor progression via NF-κB signaling pathway in epithelial ovarian cancer
Nuclear factor-kappaB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue. Clin ... NF-κB is an important multifunctional transcription factor, with a wide range of biological activities. Studies have shown high ... Scatter-factor and semaphorin receptors: cell signalling for invasive growth. Nat Rev Cancer. 2002;2:289-300 ... Expression and regulation of tumor necrosis factor alpha in normal and malignant ovarian epithelium. Molecular cancer ...http://www.jcancer.org/v08p3733.htm
Silencing of hERG1 Gene Inhibits Proliferation and Invasion, and Induces Apoptosis in Human Osteosarcoma Cells by Targeting the...
Nuclear factor-κB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue. Clin Cancer ... Series introduction: the transcription factor NF-κB and human disease. J Clin Invest. 2001;107(1):3-6 ... which function as transcription factors and consist of special DNA binding peptides that participate in cellular physiological ... Wang et al. reported that the tumor necrosis factor α (TNF-α) is a regulator of tumor cell apoptosis in a hERG1 expression ...http://jcancer.org/v07p0746.htm
Phycocyanin: A Potential Drug for Cancer Treatment
... transcription factors (Janus kinase 3 (Jak3) and signal transducers and activators of transcription 3(stat3)) and enhanced the ... Copetti T, Bertoli C, Dalla E, Demarchi F, Schneider C. p65/RelA modulates BECN1 transcription and autophagy. Molecular and ... transcription factors (Janus kinase 3 (Jak3), signal transducers and activators of transcription 3(stat3)), and enhance the ... Phycocyanin can induce NF-κB nuclear translocation, since NF-κB is one of the transcription factors of Beclin 1 which is a key ...http://www.jcancer.org/v08p3416.htm
Post-transcriptional Regulation of Genes Related to Biological Behaviors of Gastric Cancer by Long Noncoding RNAs and MicroRNAs
... tumor-suppressor runt domain transcription factor 1) . H19/miR-675 axis accelerates the activation of the AKT/mTOR ... RELA, FOS,. IKKε. When over-expressed, miR-7 targets the 3ʹ-UTR of RELA and FOS and inhibits their protein expression. MiR-7 ... MiR-7 also mediates RELA indirectly by suppressing the protein level of IKKɛ; in turn, IKKɛ/RELA inhibits miR-7, forming a miR- ... Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells. Int J Radiat Oncol Biol Phys. ...http://www.jcancer.org/v08p4141.htm