Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukemia cells | Blood Journal
The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin ... B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle ... with particular emphasis on the transcription factor, nuclear factor-κB (NF-κB). Previous experiments have shown that ... The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance. Biochim Biophys Acta. 2000;1470:M55- ...http://www.bloodjournal.org/content/98/8/2301?ijkey=1e79d509edff2b3c11f53b51d72314a866c7761f&keytype2=tf_ipsecsha&sso-checked=true
Vascular Endothelial Growth Factor Inhibits the Development of Dendritic Cells and Dramatically Affects the Differentiation of...
Role of NF-κB transcription factor in the effects mediated by VEGF.. What could be the possible molecular mechanisms of these ... Several subunits of NF-κB have been identified: p50, p52, p65 (RelA), cRel, and RelB. These subunits form both homodimeric and ... Infusion of VEGF was associated with inhibition of the activity of the transcription factor NF-κB in bone marrow progenitor ... Vascular endothelial growth factor/vascular permeability factor is detectable in the sera of tumor-bearing mice and cancer ...http://www.bloodjournal.org/content/92/11/4150?ijkey=bbecb0adf177b009e8dc10639b87ca4fe47d5fdc&keytype2=tf_ipsecsha&sso-checked=true
Biologic sequelae of nuclear factor-κB blockade in multiple myeloma: therapeutic applications | Blood Journal
The Rel/nuclear factor-κB (Rel/NF-κB) proteins comprise a family of transcription factors, which is conserved from Drosophilato ... NF-κB commonly refers to the p50-RelA heterodimer, which is the major Rel complex. In most cell types, NF-κB is present ... The transcription factor nuclear factor-κB (NF-κB) confers significant survival potential in a variety of tumors. Several ... B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle ...http://www.bloodjournal.org/content/99/11/4079?ijkey=10470417794f0ca20731654f60aac3e12e7e6476&keytype2=tf_ipsecsha&sso-checked=true
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma | Blood Journal
Deregulated NF-κB signaling is a hallmark of most lymphoid malignancies, and recurrent mutations in NF-κB transcription factors ... IκBε is a key regulator of B cell expansion by providing negative feedback on cRel and RelA in a stimulus-specific manner. J ... remained an independent factor for poor outcome (supplemental Table 5), even when restricting the analysis to patients treated ... NFKBIE aberrations remained an independent factor in multivariate analysis (P = .003) and when restricting the analysis to ...http://www.bloodjournal.org/content/128/23/2666?sso-checked=true