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*  Apatot / Morinda citrifolia / Noni / INDIAN MULBERRY: Philippine Alternative Medicine / Medicinal Herbs / StuartXchange
Genotoxicity and short-term toxicity test showed no toxicity at doses between 500 and 2000 mg/kg. 1000 mg/kg orally was the ... Subchronic Oral Toxicity Study: A subchronic oral toxicity study in Sprague-Dawley rats showed a no-observed-adverse-effect ... Dermal Toxicity Study / Fruit Extract: Study evaluated the in vivo acute and subacute dermal toxicity of ethanolic extract of M ... Extract showed no toxicity. In non-small-cell lung cancer (NSCLC) A549-induced BALB/c mice, there was significant increase in ...
http://www.stuartxchange.com/Apatot
*  toxicity testing Market Research
... anitako at tpts1.seed.net.tw anitako at tpts1.seed.net.tw Tue Apr 25 23:34:21 EST 1995 * ... Dear Reader: I need some Market Research about toxicant testing. Where could I get the imformation (Internet,gopher.....)? The ...
http://www.bio.net/bionet/mm/neur-sci/1995-April/017939.html
*  New Approaches and Alternatives for Toxicity Testing
... and Ecotoxicity Testing New Approaches and Alternatives for Toxicity, Fate and Transport, and Ecotoxicity Testing ... Session I - Toxicity Testing Strategies and Model Systems. May 14, 2018 • 1:00 - 3:00 p.m. EDT. To view an archive, visit EPA's ... In the first session, speakers provided an overview of toxicity testing strategies to advance the use of 21st-century science ... discussed the use of zebrafish for toxicity testing and its ability to help advance 21st-century science. She presented a ...
https://www.niehs.nih.gov/research/supported/centers/srp/events/riskelearning/new_approaches/index.cfm
*  Browsing by Subject "Toxicity tests"
A number of aquatic toxicity tests have been established for South African use, which include fish and Daphnia lethality tests ... Toxicity assessment of reference and natural freshwater sediments with the luminotox assay  ... We (the authors) examined the possibility of adapting the LuminoTox, a recently-commercialised bioanalytical testing procedure ... microbiotests, and short-term chronic tests. Studies on effluents and surface waters showed ... ...
http://researchspace.csir.co.za/dspace/browse?type=subject&order=ASC&rpp=20&value=Toxicity+tests
*  Ocular Toxicity Test Method Evaluations
Pyrogen Tests Ocular Toxicity Test Method Evaluations. Ocular toxicity testing, one of the four most commonly conducted product ... OptiSafe Test Method. OptiSafe is an in vitro test method in which a test substance is applied to a semipermeable membrane. ... Short Time Exposure Test The short time exposure (STE) test is an in vitro test proposed for identifying ocular irritants. ... Despite progress in alternative ocular toxicity test method development, no alternative test method has been adopted by ...
https://ntp.niehs.nih.gov/pubhealth/evalatm/test-method-evaluations/ocular/index.html
*  Toxicity Test Kit Articles on Environmental XPRT
Find toxicity test kit articles on Environmental XPRT, the world's largest environmental industry marketplace and information ... toxicity test kit Articles. Related terms for "toxicity test kit ": toxicity test articles , test kit articles , acute toxicity ... The proposed toxicity test is based on the respirometric characteristics of the bacteria according to the principals of ... Development of Water Quality Test Kit Based on Substrate Utilization and Toxicity Resistance in River Microbial Communities ...
https://www.environmental-expert.com/articles/keyword-toxicity-test-kit-35155
*  Genetic Toxicity Test Articles on Environmental XPRT
Find genetic toxicity test articles on Environmental XPRT, the world's largest environmental industry marketplace and ... genetic toxicity test Articles. Related terms for "genetic toxicity test ": toxicity test articles , genetic toxicity articles ... Optimization of culturing conditions for toxicity testing with the alga Oophila sp. (Chlorophyceae), an amphibian endosymbiont ... The strain of Hyalella azteca (Saussure: Amphipoda) commonly used for aquatic toxicity testing in the US has been shown to ...
https://www.environmental-expert.com/articles/keyword-genetic-toxicity-test-78283
*  New Guidelines for Toxicity Testing of Oligonucleotide Drugs
When it comes to testing their potential to cause reproductive and developmental harm, oligonucleotide-based therapeutics ... Drug Toxicity. Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a drug, ... New consensus guidelines for toxicity testing that take into consideration the combined chemical and biological characteristics ... When it comes to testing their potential to cause reproductive and developmental harm, oligonucleotide-based therapeutics ...
http://www.medindia.net/news/new-guidelines-for-toxicity-testing-of-oligonucleotide-drugs-143232-1.htm
*  A new approach to practical acute toxicity testing | SpringerLink
A method for the investigation of the acute toxicity of an unknown chemical substance, with an estimation on the LD50, is ... Bass R, Günzel P, Henschler D, König J, Lorke D, Neubert D, Schütz E, Schuppan D, Zbinden G (1982) LD50 Versus Acute Toxicity, ... A method for the investigation of the acute toxicity of an unknown chemical substance, with an estimation on the LD50, is ... Trevan JW (1927) The error of determination of toxicity. Proc R Soc (London) Ser. B. 101: 483-514Google Scholar ...
https://link.springer.com/article/10.1007%2FBF01234480
*  Alternative Approaches for Acute Inhalation Toxicity Testing
Currently accepted guidelines for inhalation toxicity tests share core principles. These inform both essential testing needs to ... Acute systemic toxicity tests identify chemicals that could cause illness or death after a single exposure. Webinars in this ... Additivity approaches may be useful for estimating toxicity of mixtures.. *A variety of available alternative test methods can ... Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements ...
https://ntp.niehs.nih.gov/pubhealth/evalatm/3rs-meetings/past-meetings/inh-web-2016/index.html
*  EPA Considering New Toxicity Testing for BPA -- Environmental Protection
... is requesting public comment on possible toxicity testing and environmental sampling to study BPA's potential environmental ... EPA Considering New Toxicity Testing for BPA. *Jul 27, 2011. Following a BPA Action Plan announced in March 2010, the U.S. ... Environmental Protection Agency (EPA) is requesting public comment on possible toxicity testing and environmental sampling to ... "The data collected under the testing EPA is considering would help EPA better understand and address the potential ...
https://eponline.com/articles/2011/07/27/epa-considering-new-toxicity-testing-for-bpa.aspx
*  The Future of Developmental Toxicity Testing | Publications | Knowledge | Exponent
John M. DeSesso recently authored an opinion that explores the future of developmental toxicity testing and how this will ... To this end, the standard safety test design for this type of endpoint was developed in the mid-1960's and has changed little ... John M. DeSesso recently authored an opinion that explores the future of developmental toxicity testing and how this will ... As a result, for at least the next few decades, the pregnant mammal will remain the final linchpin in teratology testing.. How ...
https://www.exponent.com/knowledge/publications/2007/06/the-future-of-developmental-toxicity-testing
*  chronic toxicity tests - oi
Tests for chronic toxicity, including cumulative effects and for evidence of potential carcinogenicity, mutagenicity, and ... human mutagens and teratogens do not have comparable effects on animals such as the small rodents customarily used for testing. ...
http://oxfordindex.oup.com/view/10.1093/oi/authority.20110803095611395
*  Flame Retardant Makers Won't Have to Do Toxicity Tests: EPA | Bloomberg Environment
... paints and other products won't have to conduct toxicity or exposure tests requested through an environmental coalition's... ... 6 asking the EPA to require the manufacturers of the three flame retardants to conduct toxicity and exposure tests because the ... other products won't have to conduct toxicity or exposure tests requested through an environmental coalition's petition, the ... Earthjustice, the Natural Resources Defense Council and other coalition participants justified their petition for toxicity and ...
https://www.bna.com/flame-retardant-makers-n57982086514/
*  Early Toxicity Testing Market to increase steadily by 2014-2022 | Medgadget
... where the toxicity of the compounds present in the test product is evaluated. Different tests are conducted to check the ... Some tests are also useful to check if the entity has toxic ... Early toxicity testing is used during clinical trials, ... Early toxicity testing is used during clinical trials, where the toxicity of the compounds present in the test product is ... However, limited awareness about the benefits of early toxicity testing and limitations of preclinical testing are expected to ...
https://www.medgadget.com/2017/10/early-toxicity-testing-market-to-increase-steadily-by-2014-2022.html
*  In vitro models for liver toxicity testing - Toxicology Research (RSC Publishing)
In vitro models for liver toxicity testing V. Y. Soldatow, E. L. LeCluyse, L. G. Griffith and I. Rusyn, Toxicol. Res., 2013, 2 ... cell lines and primary isolated liver cells are currently the most widely used in vitro models for liver toxicity testing. ... of hepatocytes from multiple individuals to improve reproducibility and enable testing of the individual-specific toxicity. ... and novel in vitro liver models and provides a perspective on the challenges and opportunities afforded by each individual test ...
http://pubs.rsc.org/en/Content/ArticleLanding/2013/TX/C2TX20051A
*  ZeGlobalTox: multi-organ toxicity testing in zebrafish | Innovation Platform
... and were awarded Solutions funding to validate the platform against compound sets with known preclinical and clinical toxicity ... A traditional in vivo single-organ test is conducted, on average, with a group of 20 rodents or dogs per tested drug, resulting ... TruLarv Galleria mellonella- a model for infection studies, toxicity testing and drug development ... Although single organ specific toxicity assays have already been commercialised, it is not yet possible to assess toxicity in ...
https://nc3rs.org.uk/crackit/zeglobaltox-multi-organ-toxicity-testing-zebrafish-1
*  Insecticides Cause Slow Starvation In Aquatic Organisms, Discovery Shows Limits Of Conventional Toxicity Tests | PlanetSave
Insecticides Cause Slow Starvation In Aquatic Organisms, Discovery Shows Limits Of Conventional Toxicity Tests. by James Ayre 0 ... It's very important to note that the "slow starvation" caused by the insecticide is undetectable by conventional toxicity tests ... may have effects completely undetected by the most-commonly used toxicity tests. ... effect observed under constant exposure to low levels of neonicotinoids is not detected by conventional toxicity tests, as they ...
https://planetsave.com/2013/05/16/insecticides-cause-slow-starvation-in-aquatic-organisms-discovery-shows-limits-of-conventional-toxicity-tests/
*  Use of Medaka in Toxicity Testing - Current Protocols
Use of Medaka in Toxicity Testing. Stephanie Padilla1, John Cowden1, David E. Hinton2, Bonny Yuen2, Sheran Law2, Seth W. ... To illustrate the utility and breadth of toxicity testing possible using medaka fish, we present protocols for assessing ... Adapting the medaka embryo assay to a high‐throughput approach for developmental toxicity testing. Neurotoxicology 27:840‐845. ... is frequently utilized for toxicity testing. While these vertebrates have many similarities with their terrestrial counterparts ...
http://www.currentprotocols.com/WileyCDA/CPUnit/refId-tx0110.html?quicktabs_cp=toc
*  RNA-interference pesticides will need special safe... ( Standard toxicity testing is inadequ...)
... testing,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters ... Standard toxicity testing is inadequate to assess the safety of a new ...RNA interference is a natural process that affects the ... RNA-interference pesticides will need special safety testing. ...Standard toxicity testing is inadequate to assess the safety ... Standard toxicity testing is inadequate to assess the safety of a new technology with potential for creating pesticides and ...
http://www.bio-medicine.org/biology-news-1/RNA-interference-pesticides-will-need-special-safety-testing-31015-1/
*  PETA Science Consortium seeks laboratories to develop nanomaterial toxicity test
... has the potential to replace the current test conducted on animals to assess the inhalation toxicity of nanomaterials. ... PETA International Science Consortium put out a request for proposals to identify facilities that can develop an in vitro test ... PETA Science Consortium seeks laboratories to develop nanomaterial toxicity test. (Nanowerk News) Today, the PETA International ... has the potential to replace the current test conducted on animals to assess the inhalation toxicity of nanomaterials. ...
https://www.nanowerk.com/nanotechnology-news/newsid=39429.php
*  ASTM E1440 - 91(2012) Standard Guide for Acute Toxicity Test with the Rotifer Brachionus
... acute toxicity, cysts, freshwater, invertebrate, LC50, marine, rotifers, toxicity test, ... Standard Guide for Acute Toxicity Test with the Rotifer Brachionus , ... E729 Guide for Conducting Acute Toxicity Tests on Test Materials with Fishes, Macroinvertebrates, and Amphibians ... thus eliminating pre-test conditions as a source of variability in the toxicity test. Cysts can be shipped inexpensively world- ...
https://www.astm.org/Standards/E1440.htm
*  Human Embryonic and Induced Pluripotent Stem Cell Based Toxicity Testing Models
... : Future Applications in New Drug Discovery. ... Human Embryonic and Induced Pluripotent Stem Cell Based Toxicity Testing Models Curr Med Chem. 2016 Jun 27. [Epub ahead of ... We focused on upcoming hESCs and hiPSCs based toxicity testing models and their future role to address safety gaps of present ... Human Embryonic and Induced Pluripotent Stem Cell Based Toxicity Testing Models: Future Applications in New Drug Discovery.. ...
http://sci.rutgers.edu/forum/showthread.php?254718-Human-Embryonic-and-Induced-Pluripotent-Stem-Cell-Based-Toxicity-Testing-Models&s=b8b1b35a9984d470a3faf3599fb41cad&p=1804823
*  Applicability of ambient toxicity testing to national or regional water-quality assessment
Toxicity testing is one type of biological monitoring that can be used to identify possible effects of toxic contaminants. ... Toxicity-test results are most effective when used as a complement to chemical analyses, hydrologic measurements, and other ... However, all toxicity-testing procedures have certain limitations that must be considered in developing the methodology... ... Based on experimentation designed to monitor responses of organisms to environmental stresses, toxicity testing may have ...
https://pubs.er.usgs.gov/publication/cir1049
*  Renewable Lubricants | Environmental Acute Toxicity Tests
... and 203 for acute toxicity testing, or OECD 210 and 211 for chronic toxicity testing. For purposes of the VGP, equivalent ... Environmental Acute Toxicity Tests Renewable Lubricants' Biobased Products are environmentally responsible lubricants that are ... RLI's fluids, including additive technology evaluation for each constituent substance, have been reviewed and tested to be ... They should be especially used where low toxicity and biodegradability properties are required. ...
http://renewablelube.com/lab-info/environmental-acute-toxicity-tests/