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*  Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma | JEM
The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor. Genes Dev. 17:1841-1854. doi:10.1101/ ... and treated with rapamycin or the TOR-kinase inhibitors PP-242 and torin (mean fold change and SEM of 5 separate experiments ... Our study provides new insight into oncogenic kinases in human lymphoma. The constitutively active PIM1 and PIM2 kinases are ... Both the AKT and PIM kinases control regulators of cap-dependent translation (Sonenberg and Hinnebusch, 2009). Both kinases can ...
http://jem.rupress.org/content/208/9/1799
*  Tor - Serine/threonine-protein kinase Tor - Drosophila melanogaster (Fruit fly) - Tor gene & protein
sp,Q9VK45,TOR_DROME Serine/threonine-protein kinase Tor OS=Drosophila melanogaster OX=7227 GN=Tor PE=1 SV=1 ... Serine/threonine-protein kinase TorAdd BLAST. 2470. Proteomic databases. PaxDb, a database of protein abundance averages across ... IPR036940. PI3/4_kinase_cat_sf. IPR018936. PI3/4_kinase_CS. IPR003151. PIK-rel_kinase_FAT. IPR014009. PIK_FAT. IPR026683. TOR. ... IPR036940. PI3/4_kinase_cat_sf. IPR018936. PI3/4_kinase_CS. IPR003151. PIK-rel_kinase_FAT. IPR014009. PIK_FAT. IPR026683. TOR. ...
http://www.uniprot.org/uniprot/Q9VK45
*  Extended Release Tacrolimus vs. Twice-Daily Tacrolimus
Tor Serine-threonine Kinases. A serine threonine kinase that controls a wide range of growth-related cellular processes. The ...
https://www.bioportfolio.com/resources/trial/189012/Extended-Release-Tacrolimus-vs-Twice-Daily-Tacrolimus.html
*  MicroRNA miR-1271 | Cancer Genetics Web
TOR Serine-Threonine Kinases. *Insulin Receptor Substrate Proteins. *Up-Regulation. *Transcription Factors ... serine/threonine-protein kinase mTOR (mTOR), and the apoptosis regulator Bcl-2 (BCL2), compared with the parental SGC7901 cells ...
http://www.cancerindex.org/geneweb/MIR1271.htm
*  Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.
Serine / metabolism. Signal Transduction / drug effects, genetics. TOR Serine-Threonine Kinases / metabolism. ... 452VLY9402/Serine; 534-82-7/Methoxyhydroxyphenylglycol; 98600C0908/Cycloheximide; EC 2.7.1.1/TOR Serine-Threonine Kinases; EC ... Keywords: Homer1a, group I mGluRs, long-term depression, translation, ERK, PI3 Kinase, mTOR, EF2 Kinase, UP states, neocortex. ... 1). In support of our hypothesis, DHPG-induced activation of PI3K, mTOR and p70 ribosomal S6 kinase (S6K) is deficient in Fmr1 ...
http://www.biomedsearch.com/nih/Disrupted-Homer-scaffolds-mediate-abnormal/22267161.html
*  mTOR/S6 kinase pathway contributes to astrocyte survival during ischemia. | CureHunter
mTOR/S6 kinase pathway contributes to astrocyte survival during ischemia. - María Dolores Pastor, Isaac García-Yébenes, Noelia ... Ribosomal Protein S6 Kinases (metabolism) *TOR Serine-Threonine Kinases. *bcl-X Protein (metabolism) ... mTOR/S6 kinase pathway contributes to astrocyte survival during ischemia.. Abstract. Neurons are highly dependent on astrocyte ... We detected a robust down-regulation of S6 kinase 1 (S6K1) mRNA that was accompanied by a sharp decrease in protein levels and ...
http://www.curehunter.com/public/pubmed19535330.do
*  A Schematic Representation of the Potential for Novel M | Open-i
TOR Serine-Threonine Kinases. Related in: MedlinePlus. © Copyright Policy Related In: Results - Collection ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2211557_pmed.0050021.g003&req=4
*  Clinicopathological Features of GlioblastomaLeft, a sag | Open-i
TOR Serine-Threonine Kinases. Related in: MedlinePlus. © Copyright Policy Related In: Results - Collection ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2211557_pmed.0050021.g001&req=4
*  uterine corpus neoplasm drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
Protein Kinases; EC 2.7.1.1 / MTOR protein, human; EC 2.7.1.1 / TOR Serine-Threonine Kinases; W36ZG6FT64 / Sirolimus ... Protein Kinases / metabolism. Sirolimus / therapeutic use. *[MeSH-minor] Aged. Aged, 80 and over. Antibiotics, Antineoplastic ... TOR Serine-Threonine Kinases. Treatment Outcome. Tumor Cells, Cultured. *COS Scholar Universe. author profiles. ...
http://www.bmlsearch.com/?kwr=uterine+corpus+neoplasm+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1
*  askin's tumor morphologic abnormality 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Protein Kinases / physiology. Receptor, IGF Type 1 / physiology. Signal Transduction. TOR Serine-Threonine Kinases ... Chemical-registry-number] EC 2.7.- / Protein Kinases; EC 2.7.1.1 / MTOR protein, human; EC 2.7.1.1 / TOR Serine-Threonine ... Mitogen-Activated Protein Kinase 1; EC 2.7.11.24 / Mitogen-Activated Protein Kinase 3; EC 2.7.11.26 / Glycogen Synthase Kinase ... Similarly, expression of a kinase-deficient (K85R) GSK3beta or GSK3beta-small interfering RNA inhibited FGF2-regulated ERK/ ...
http://www.bmlsearch.com/?kwr=askin
*  acinic cell tumor salivary gland 2005:2010 - BioMedLib™ search engine
TOR Serine-Threonine Kinases / metabolism. *[MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. DNA, ... TOR Serine-Threonine Kinases; EC 2.7.10.1 / EGFR protein, human; EC 2.7.10.1 / ERBB2 protein, human; EC 2.7.10.1 / Receptor, ...
http://bmlsearch.com/?kwr=acinic%20cell%20tumor%20salivary%20gland%202005:2010
*  ZFIN Publication: McCarthy et al., 2013
TOR Serine-Threonine Kinases/metabolism. *Zebrafish/abnormalities*. *Zebrafish/genetics. *Zebrafish Proteins/genetics ...
http://zfin.org/ZDB-PUB-130726-17
*  ZFIN Publication: Blackburn et al., 2014
TOR Serine-Threonine Kinases/metabolism*. *Zebrafish. PubMed:. 24613413 Full text @ Cancer Cell ...
http://zfin.org/ZDB-PUB-140513-379
*  acinar carcinoma 2005:2010 - BioMedLib™ search engine
TOR Serine-Threonine Kinases; EC 2.7.10.- / PERK kinase; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.1 / eIF-2 ... Chemical-registry-number] EC 2.7.12.2 / MAP Kinase Kinase 4; EC 2.7.12.2 / MAP Kinase Kinase 7; EC 2.7.12.2 / Map2k7 protein, ... TOR Serine-Threonine Kinases; EC 2.7.1.1 / mTOR protein, mouse; W36ZG6FT64 / Sirolimus ... MAP Kinase Kinase 4 / genetics. MAP Kinase Kinase 7 / genetics. Pancreatic Neoplasms / metabolism. Proto-Oncogene Proteins p21( ...
http://bmlsearch.com/?kwr=acinar%20carcinoma%202005:2010
*  Welcome to LibAge, the ageing reference resource
Entries tagged TOR Serine-Threonine Kinases (27). Sort:. Number of citations. Author. Title. Year. PubMed ID. ... 2004) "Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway." Curr. Biol. 14(10):885-890 ( ... 2006) "Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity." Cell Metab. 4(2):133-142 (PubMed) ... 2009) "Ribosomal protein S6 kinase 1 signaling regulates mammalian life span." Science 326(5949):140-144 (PubMed) ...
http://la.ageing-map.org/entries/tags/5993/
*  "Loss of mTOR signaling affects cone function, cone structure and expre" by Shan Ma, Aditya Venkatesh et al.
One of the downstream targets of PI3K is the kinase mammalian target of rapamycin (mTOR), which is a key regulator of cell ... They are metabolically highly active requiring phosphoinositide 3-kinase (PI3K) activity for long-term survival. ... Phosphatidylinositol 3-Kinases; Retinal Cone Photoreceptor Cells; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases ... One of the downstream targets of PI3K is the kinase mammalian target of rapamycin (mTOR), which is a key regulator of cell ...
https://escholarship.umassmed.edu/oapubs/2712/
*  Target of rapamycin-mediated amino acid signaling in mosquito anautogeny | PNAS
Amino acid signaling is commonly mediated by the TOR kinase signal transduction pathway (16, 27). TOR is a serine/threonine ... and this complex binds to TOR and inhibits its kinase activity (25). To determine whether the TOR protein kinase is a part of ... The TOR kinase is inactive and TSC2 blocks TOR signaling. The GATAr transcription factor binds and inactivates the Vg promoter ... The C-terminal domains of TOR are highly conserved. Amino acid identity between the TOR kinases of S. cerevisiae (ScTOR1) and A ...
https://www.pnas.org/content/101/29/10626.full
*  OPUS at UTS: Leucine Improves Glucose and Lipid Status in Offspring from Obese Dams, Dependent on Diet Type, but not Caloric...
TOR Serine-Threonine Kinases. en_US. dc.subject.mesh. Real-Time Polymerase Chain Reaction. en_US. ... TOR Serine-Threonine Kinases. en_US. dc.subject.mesh. Triglycerides. en_US. ...
https://opus.lib.uts.edu.au/handle/10453/31525
*  PDGFRA | Cancer Genetics Web
TOR Serine-Threonine Kinases. *Stem Cell Factor. *Benzamides. *Exons. *Risk Factors. *Tissue Array Analysis ... phosphatidylinositol 3-kinase (PI3K), Jun N-terminal kinase (JNK)/mitogen-activated protein kinase (MAPK), transforming growth ... positive regulation of phosphatidylinositol 3-kinase activity - positive regulation of phosphatidylinositol 3-kinase cascade - ... A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic ...
http://cancer-genetics.org/PDGFRA.htm
*  A first in man, dose-finding study of the mTORC1/mTORC2 inhibitor OSI-027 in patients with advanced solid malignancies.
Protein Kinase Inhibitors. TOR Serine-Threonine Kinases. Triazines. Young Adult. Research team. Prostate Cancer Targeted ... BACKGROUND: The kinase activity of mTOR involves 2 multiprotein complexes, (mTORC1-mTORC2). Targeting mTORC1 with rapalogues ...
https://repository.icr.ac.uk/handle/internal/2960
*  mTOR complex 2 phosphorylates IMP1 cotranslationally to promote IGF2 production and the proliferation of mouse embryonic...
TOR Serine-Threonine Kinases Main Research Area: Science/technology Publication Status: Published Review type: Peer Review ...
http://www.forskningsdatabasen.dk/catalog/235836957
*  590 4.22 2010
TOR Serine-Threonine Kinases[MESH]*,Transcription Factors/metabolism[MESH]*,Tumor Suppressor Protein p53/genetics/metabolism[ ... p38 Mitogen-Activated Protein Kinases/*metabolism[MESH]. Activation of the AMP-activated protein kinase-p38 MAP kinase pathway ... Activation of the AMP-activated protein kinase-p38 MAP kinase pathway mediates apoptosis induced by conjugated linoleic acid in ... BibRecord , Autor = Hsu YC; Meng X; Ou L; Ip MM , Titel = Activation of the AMP-activated protein kinase-p38 MAP kinase pathway ...
http://www.kidney.de/mlpefetch.php?search=19932174