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*  JAIRO | The efficacy of preoperative positron emission tomography-computed tomography (PET-CT) for detection of lymph node...
The efficacy of preoperative positron emission tomography-computed tomography (PET-CT) for detection of lymph node metastasis in cervical and endometrial cancer : clinical and pathological factors influencing it(審査報告)The efficacy of preoperative positron emission tomography-computed tomography (PET-CT) for detection of lymph node metastasis in cervical and endometrial cancer : clinical and pathological factors influencing it(審査報告) ...
http://jairo.nii.ac.jp/0050/00052572/en
*  Tumor Volumes Measured From Static and Dynamic F-18-fluoro-2-deoxy-D-glucose Positron Emission Tomography-Computed Tomography...
Objective: The objective of this study was to compare the accuracy of calculating the primary tumor volumes using a gradient-based method and fixed threshold methods on the standardized uptake value (SUV) maps and the net influx of FDG (Ki) maps from positron emission tomography-computed tomography (PET-CT) images. Materials and Methods: Newly diagnosed patients with head and neck cancer were recruited, and dynamic PET-CT scan and T2-weighted magnetic resonance imaging were performed. The maps of Ki and SUV were calculated from PET-CT images. The tumor volumes were calculated using a gradient-based method and a fixed threshold method at 40% of maximal SUV or maximal Ki. Four kinds of volumes, VOLKi-Gra (from the Ki maps using the gradient-based method), VOLKi-40% (from the Ki maps using the threshold of 40% maximal Ki), VOLSUV-Gra (from the SUV maps using the gradient-based method), and VOLSUV-40% (from the SUV maps using the threshold of 40% maximal SUV), were acquired and ...
http://umu.diva-portal.org/smash/record.jsf?pid=diva2:733273
*  Study of 18F-FEC for Positron Emission Tomography-Computed Tomography (PET-CT) Imaging of GBM - Tabular View - ClinicalTrials...
Positron Emission Tomography-Computed Tomography (PET-CT) with injection of 18F-fluoroethylcholine (FEC) could be a useful tool in the evaluation and follow-up of patients who have been diagnosed with glioblastoma multiforme (GBM) and who are treated with radiotherapy and temozolomide by allowing, for example, the distinction of necrosis from tumour tissue. This tool could help the clinician in making therapeutic decisions for GBM patients ...
https://clinicaltrials.gov/ct2/show/record/NCT00943462
*  Management of Gastric Varices in the Pediatric Population with Balloon-Occluded Retrograde Transvenous Obliteration (BRTO)...
It is unknown whether spontaneous gastrorenal shunts actually develop in the pediatric population. The minimum age documented in studies from Asia is 32 (range 32-44) years. This study describes three pediatric patients undergoing balloon-occluded retrograde transvenous obliteration (BRTO) for bleeding gastric varices with two of the three patients undergoing combined partial splenic embolization. The first BRTO is a selective-BRTO via a surgical splenorenal shunt (15 years old) and the other two patients underwent conventional-BRTO via a spontaneous gastrorenal shunt (8 and 14 years old). The recurrent significant bleeding that they exhibited before the combined endovascular therapy did not recur for an average of 7.1 (range 1.4-14) months. In the second patient, quantitative digitally subtracted angiography was utilized to evaluate the inline portal venous flow before and after BRTO. ...
https://www.osti.gov/scitech/biblio/22470109-management-gastric-varices-pediatric-population-balloon-occluded-retrograde-transvenous-obliteration-brto-utilizing-sodium-tetradecyl-sulfate-foam-sclerosis-without-partial-splenic-artery-embolization
*  Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography imaging in patients with carcinoma of the...
PURPOSE To assess the value of (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in patients with nasopharyngeal carcinoma as compared with PET and conventional imaging (CI) alone, and to assess the impact of PET/CT on further clinical management. METHODS AND MATERIALS Thirty-three patients with nasopharyngeal carcinoma had 45 PET/CT examinations. The study was a retrospective analysis. Changes in patient care resulting from the PET/CT studies were recorded. RESULTS Positron emission tomography/computed tomography had sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 92%, 90%, 90%, 90%, and 91%, respectively, as compared with 92%, 65%, 76%, 86%, and 80% for PET and 92%, 15%, 60%, 60%, and 60% for CI. Imaging with PET/CT altered further management of 19 patients (57%). Imaging with PET/CT eliminated the need for previously planned diagnostic procedures in ...
https://www.semanticscholar.org/paper/Fluorine-18-fluorodeoxyglucose-positron-emission-t-Gordin-Golz/3db18bfd163c51a7bb585ce0e3192946c15f8510
*  Positron-emission tomography | Article about Positron-emission tomography by The Free Dictionary
Looking for Positron-emission tomography? Find out information about Positron-emission tomography. see PET scan PET scan or positron emission tomography , a medical imaging technique that monitors metabolic, or biochemical, activity in the brain and other... Explanation of Positron-emission tomography
https://encyclopedia2.thefreedictionary.com/Positron-emission+tomography
*  Abstract 2435: Simvastatin Attenuates Plaque Inflammation- Evaluation by Fluorodeoxyglucose Positron Emission Tomography - |...
BACKGROUND: Inflammation plays a key role in progression and destabilization of atherosclerotic plaque. [18F]-fluorodeoxyglucose positron emission tomography (18FDG-PET) is a promising tool for visualizing inflammation of atherosclerotic plaque. Anti-inflammatory action is one of the pleiotropic effects of statins.. OBJECTIVE: We investigated whether simvastatin attenuates plaque inflammation by using 18FDG-PET co-registered with computed tomography.. METHODS and RESULTS: Forty-three consecutive subjects, who underwent 18FDG-PET for cancer screening and had 18FDG uptakes in the thoracic aorta and/or the carotid arteries, were randomized to either statin group receiving simvastatin (n=21) or diet group receiving dietary managements (n=22). The maximum standardized uptake values (SUVs) were measured in individual plaques, and were averaged for analysis of the subject-wise results. The responses were assessed after 3-month treatments. PET revealed 117 and 123 18FDG-positive ...
http://circ.ahajournals.org/content/114/Suppl_18/II_501.1
*  北京大学医学部机构知识库(IR@PKUHSC): Tumor Volumes Measured From Static and Dynamic F-18-fluoro-2-deoxy-D-glucose Positron Emission...
Objective: The objective of this study was to compare the accuracy of calculating the primary tumor volumes using a gradient-based method and fixed threshold methods on the standardized uptake value (SUV) maps and the net influx of FDG (Ki) maps from positron emission tomography-computed tomography (PET-CT) images.. Materials and Methods: Newly diagnosed patients with head and neck cancer were recruited, and dynamic PET-CT scan and T2-weighted magnetic resonance imaging were performed. The maps of Ki and SUV were calculated from PET-CT images. The tumor volumes were calculated using a gradient-based method and a fixed threshold method at 40% of maximal SUV or maximal Ki. Four kinds of volumes, VOLKi-Gra (from the Ki maps using the gradient-based method), VOLKi-40% (from the Ki maps using the threshold of 40% maximal Ki), VOLSUV-Gra (from the SUV maps using the gradient-based method), and VOLSUV-40% (from the SUV maps using the threshold of 40% maximal SUV), were acquired and ...
http://ir.bjmu.edu.cn/handle/400002259/56369
*  Atypical spleen tuberculosis in a melanoma patient accidentally detected during a 18F‑FDG PET/CT study: Case report
The present study, discussed a rare case of a 50‑year‑old woman who was treated for malignant melanoma and underwent 18F‑fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) examination for evaluation of disease. 18F‑FDG‑PET/CT examination was performed from the top of the head down to the knee using a Gemini TF PET/CT scanner 60 min following intravenous injection of radiotracer with mean activity of 364±75 MBq. Previous performed laboratory test and clinical examination was irrelevant. By abdominal ultrasound no abnormalities in abdominal organs beside the liver cyst were found. The 18F‑FDG PET/CT exam showed an increased glucose metabolism in the anterior pole of the spleen, which was considered as melanoma metastasis. Splenectomy was performed and histopathology examination tuberculous lesion in the spleen was revealed. Histopathology examination showed epithelioid granuloma and in correlation with the patient's history allowed to ...
https://www.spandidos-publications.com/mco/8/1/89
*  The Use of High Resolution Chest Computed Tomography in Alpha-1 Antitrypsin Deficiency - Full Text View - ClinicalTrials.gov
AAT deficiency is a genetic disorder associated with emphysema. Spirometry, the lung function test that measures how well the lungs exhale air, is used to diagnose and track the progression of emphysema. Some studies have suggested that forced expiratory volume in 1 second (FEV1) measurements, a type of spirometry test, may lack accuracy in detecting disease progression in cases of severe AAT deficiency. Another method, high resolution chest CT scans, may be more accurate at measuring the progression of emphysema. The purpose of this study is to determine if high resolution CT scans are better at detecting the progression of emphysema than lung function tests. Results from this study may lead to the development of a more accurate way to assess lung tissue loss and may improve the understanding of lung destruction in AAT deficiency.. This study will last 4 years and will enroll people with AAT deficiency who have nearly normal lung function test results. Study visits, each lasting about 4 hours, ...
https://clinicaltrials.gov/ct2/show/NCT00532805?cond=%22Alpha+1-antitrypsin+deficiency%22&rank=9
*  Global Positron Emission Tomography Scanners Market Research Report 2016 | Global Market Research Reports
2016 Global Positron Emission Tomography Scanners Industry Report is a professional and in-depth research report on the world's major regional market conditions of the Positron Emission Tomography Scanners industry, focusing on the main regions (North America, Europe and Asia) and the main countries (United States, Germany, Japan and China).
http://www.gosreports.com/global-positron-emission-tomography-scanners-market-research-report-2016/
*  Adult Hodgkin Lymphoma Treatment (PDQ )
Recommendations for posttreatment follow-up are not evidence based, but a variety of opinions have been published for high-risk patients who present with advanced-stage disease or for patients who achieve less-than-complete remission by positron emission tomography-computed tomography (PET-CT) scans at the end of therapy. [1] [2] [3] [4] For patients with a negative PET-CT scan at the end of therapy, routine scans are not advised; opportunistic scanning is applied when patients present with suspicious symptoms, physical findings, or laboratory tests.. Among 6,840 patients enrolled in German Hodgkin Study Group trials, with a median follow-up of 10.3 years, 141 patients relapsed after 5 years, compared with 466 patients who relapsed within 5 years. [5] Treatment-related adverse effects and late relapses may occur even beyond 20 years of follow-up. [5]. Patients who experience a relapse after initial wide-field, high-dose radiation therapy have a good prognosis. Combination ...
https://imsdd.meb.uni-bonn.de/cancer.gov/CDR0000062675.html
*  Role of Multi-Detector Row CT in Hemoptysis - Sumer's Radiology Blog
Unique blend of academic excellence and entrepreneurship, heading leading firms in India- Teleradiology Providers, pioneering company providing teleradiology services and DAMS (Delhi Academy of Medical Sciences) Premier test preparation institute in India for MD/MS/MCI preparation. He has also been an invited faculty member at various conferences, including Teleradiology in IRIA 2008 and 2011, Hospital Build Middle East, Congress of the Brain Tumor Radiology in Neuro-oncology Society. Dr. Sethi is Editor-in-Chief of Internet Journal of Radiology. He has a keen interest in Web 2.0 technologies and in maintaining his famous radiology blog, which has been featured in multiple international journals.. ...
http://sumerdoc.blogspot.com/2006/02/role-of-multidetector-row-ct-in.html
*  Tracheobronchomalacia in infants and children: multidetector CT evaluation. - Semantic Scholar
Tracheobronchomalacia (TBM) is the most common congenital central airway anomaly, but it frequently goes unrecognized or is misdiagnosed as other respiratory conditions such as asthma. Recent advances in multidetector computed tomography (CT) have enhanced the ability to noninvasively diagnose TBM with the potential to reduce the morbidity and mortality associated with this condition. Precise indications are evolving but may include symptomatic pediatric patients with known risk factors for TBM and patients with otherwise unexplained impaired exercise tolerance; recurrent lower airways infection; and therapy-resistant, irreversible, and/or atypical asthma. With multidetector CT, radiologists can now perform objective and quantitative assessment of TBM with accuracy similar to that of bronchoscopy, the reference standard for diagnosing this condition. Multidetector CT enables a comprehensive evaluation of pediatric patients suspected of having TBM by facilitating accurate diagnosis, ...
https://www.semanticscholar.org/paper/Tracheobronchomalacia-in-infants-and-children-mult-Lee-Boiselle/14146c80dc8a453df414c415ae90cefd2e9d5be1
*  Chemotherapy Based on Positron Emission Tomography Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma - Full...
This phase II trial studies how well chemotherapy based on positron emission tomography (PET) scan works in treating patients with stage I or stage II Hodgkin lymphoma. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. Radiation therapy uses high energy x-rays to kill cancer cells. Giving combination chemotherapy together with radiation therapy may kill more cancer cells and allow doctors to save the part of the body where the cancer started. Comparing results of diagnostic procedures, such as PET scan, done before, during, and after chemotherapy may help doctors predict a patient's response to treatment and help plan the best treatment ...
https://clinicaltrials.gov/ct2/show/study/NCT01132807?show_locs=Y
*  Chemotherapy Based on Positron Emission Tomography Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma - Full...
This phase II trial studies how well chemotherapy based on positron emission tomography (PET) scan works in treating patients with stage I or stage II Hodgkin lymphoma. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. Radiation therapy uses high energy x-rays to kill cancer cells. Giving combination chemotherapy together with radiation therapy may kill more cancer cells and allow doctors to save the part of the body where the cancer started. Comparing results of diagnostic procedures, such as PET scan, done before, during, and after chemotherapy may help doctors predict a patient's response to treatment and help plan the best treatment ...
https://clinicaltrials.gov/ct2/show/NCT01132807?recr=Open&state1=NA%3AUS%3AVT&rank=14
*  Chemotherapy Based on Positron Emission Tomography Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma - Full...
This phase II trial studies how well chemotherapy based on positron emission tomography (PET) scan works in treating patients with stage I or stage II Hodgkin lymphoma. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. Radiation therapy uses high energy x-rays to kill cancer cells. Giving combination chemotherapy together with radiation therapy may kill more cancer cells and allow doctors to save the part of the body where the cancer started. Comparing results of diagnostic procedures, such as PET scan, done before, during, and after chemotherapy may help doctors predict a patient's response to treatment and help plan the best treatment ...
https://clinicaltrials.gov/show/NCT01132807%A0
*  'positron emission tomography' Protocols and Video...
Video articles in JoVE about positron emission tomography include 'Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images', 'Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG', 'A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space', 'Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT)', 'Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models', 'The Bioconjugation and Radiosynthesis of 89Zr-DFO-labeled Antibodies', 'Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET: Dopamine Movies of ...
https://www.jove.com/keyword/positron+emission+tomography
*  Multislice Computed Tomography in Infective Endocarditis | JACC: Journal of the American College of Cardiology
Pre-operative assessment of coronary artery disease with conventional coronary angiography has been recommended in the guidelines of the American College of Cardiology/American Heart Association for selected patients scheduled for cardiac valve surgery (15). Recently introduced multislice CT allows noninvasive coronary artery imaging and has been shown to reliably exclude significant coronary artery stenosis (8,9). The major advantage of multislice CT over conventional coronary angiography in patients with acute IE is its noninvasiveness and thus avoidance of the high embolization risk of valvular vegetations during catheter manipulation. Once spread into the systemic arterial circulation, those vegetations can cause severe complications such as cerebral or peripheral embolization (17).. In this study, multislice CT showed an excellent diagnostic performance in assessing morphologic abnormalities commonly seen in patients with IE. Accuracy of vegetation, abscess, and pseudoaneurysm detection ...
http://www.onlinejacc.org/content/53/5/436
*  Endovascular thrombectomy for M2 occlusions: comparison between forced arterial suction thrombectomy and stent retriever...
The initial neurological examination, including the assessment of the NIHSS score, was performed in the emergency room. Non-enhanced brain CT scans were performed immediately to rule out intracerebral hemorrhage (ICH). If no ICH was evident on CT scans, intravenous recombinant tissue plasminogen activator (rtPA; Actilyse; Boehringer Ingelheim, Basel, Switzerland) was administered in accordance with the guidelines for early management (within 3 hours of symptom onset up to December 2012 and within 4.5 hours since January 2013) of adults with ischemic stroke.13 Vascular imaging (CT angiography or MR angiography) and diffusion-weighted MRI were conducted subsequently. The institutional criteria for EVT were as follows: (1) AIS corresponding to arterial occlusion on CT angiography or MR angiography; (2) infarction volume on CT or diffusion-weighted MRI less than half of the corresponding vascular territory; and (3) no evidence of well-developed parenchymal hyperintensity on FLAIR or T2-weighted ...
http://jnis.bmj.com/content/9/7/626
*  CML Leukemia and Lymphoma - Volume 22 Issue 4 - Non-Hodgkin Lymphoma
Trotman J, Luminari S, Boussetta S et al.. University of Sydney, Sydney, NSW, Australia.. Lancet Haematol 2014;1:e17-27.. Christopher Fox's review: Although patients with follicular lymphoma (FL) can typically expect a long survival, significant clinical and biological heterogeneity is recognized. Reliably predicting the outcome for an individual, however, is not straightforward, and patients with a particularly poor outlook are not reliably identified by existing prognostic indices. Positron emission tomography-computed tomography (PET-CT) is a powerful prognostic tool in Hodgkin lymphoma, but fewer data are available on the value of PET-CT for response assessment in FL.. The present analysis applied the 5-point Deauville score to a large cohort of patients with FL, pooled from three prospective cooperative group studies (J Clin Oncol 2011;29:3194-200, J Clin Oncol 2012;30:4317-22, Ann Oncol 2014;25:442-7), to provide a precise correlation between post-induction PET and ...
http://remedicajournals.com/CML-Leukemia-and-Lymphoma/BrowseIssues/Volume-22-Issue-4/Article-Non-Hodgkin-Lymphoma
*  Focus areas for increased utilization of pet/ct
PET/CT is generally not useful in CLL/SLL but can assist in directing nodal biopsy if Richter's transformation is suspected. a. Initial staging: PET/CT scan considered 'useful in selected cases'. b. Restaging after completion of treatment: imaging should be performed whenever there are clinical indications. If PET/CT is used in follow-up, progressive disease should be histologically documented (e.g., biopsy) to rule out transformation c. Non-gastric MALT lymphoma, marginal zone lymphoma (nodal, splenic), a. Initial staging: PET/CT scan considered 'useful in selected cases'. a. Initial staging: PET/CT scan considered 'useful under certain a. Initial staging: PET/CT scan considered 'essential'. b. Restaging after completion of treatment: repeat all positive studies. Biopsy of PET-positive sites is recommended before changing course of treatment. The optimum timing of PET/CT is unknown; however, waiting a minimum of 8 weeks to repeat PET/CT is suggested. False positives may occur due to ...
http://pdfmedsearch.com/p/petct.gr1.html
*  Difficult to control epilepsy in Young Female: a common problem in a low resource setting
13-year old girl presented to the medical outpatient department with epilepsy diagnosed within the preceding 3 months. However, her seizures were becoming more frequent despite being on Carbamazepine and Phenobarbital at maximal tolerable dosages. She had no recent history of head trauma neither any other medical illness. Her physical examination was unremarkable. Her full blood count, liver and kidney function tests were within normal limits. A Brain CT scan was ordered which revealed multiple calcified and vesicular cysts within the Brain parenchyma; features consistent with Neurocysticercosis. The stool examination was negative for Taenia species ova. She was treated with Albendazole 400mg tid for 1 month and subsequent CT scans at 4 weekly intervals showed marked reduction in the number of active (vesicular cysts). Brain CT scans showing multiple vesicular cysts before treatment with Albendazole (A and B) and after treatment (C and D)
http://www.panafrican-med-journal.com/content/article/18/212/full/
*  Percutaneous needle biopsy of the mediastinum: review of 94 procedures
Comparison of CT-Guided Percutaneous Biopsy with and Without Registration of Prior PET/CT Images to Diagnose Mediastinal Tumors. Yokoyama, Koichi; Ikeda, Osamu; Kawanaka, Koichi; Nakasone, Yutaka; Tamura, Yoshitaka; Inoue, Seijiro; Sakamoto, Fumi; Yoshida, Morikatsu; Shiraishi, Shinya; Yamashita, Yasuyuki // CardioVascular & Interventional Radiology;Oct2014, Vol. 37 Issue 5, p1306 Purpose: To compare computed tomography (CT)-guided percutaneous biopsy with and without registration of prior positron emission tomography (PET)/CT images in the diagnosis of mediastinal tumors. Methods: We performed clinically indicated percutaneous biopsy in 106 patients with mediastinal... ...
http://connection.ebscohost.com/c/articles/66055180/percutaneous-needle-biopsy-mediastinum-review-94-procedures
*  Endoscopic ultrasound guided biopsy of mediastinal lesions has a major impact on patient management | Thorax
In the evaluation of patients either suspected of having lung cancer or with an already established diagnosis, the goal is to obtain a tissue diagnosis and/or to classify the cancer according to the TNM classification.. When lung cancer involves the mediastinum, either by direct tumour invasion (T4 disease) or as lymph node metastases (N2/N3 disease), surgery is usually unrewarding.. Chest CT scanning alone is not recognised as proof of N2/N3 disease at our centre because of growing evidence of its poor accuracy (around 80%).11-13 Mediastinoscopy has until recently been the method of choice if mediastinal tumour growth is suspected by CT scanning. However, the area accessible for mediastinoscopy is limited to the anterior part of the mediastinum. The invasive procedure is performed under general anaesthesia with a complication rate of 2-3%. In 10% of patients who undergo thoracotomy after a negative mediastinoscopy, N2/N3 disease is nevertheless established.14,15 Up to 10% of lung cancer ...
http://thorax.bmj.com/content/57/2/98