Retinal Birefringence Measurement With Polarization Sensitive Fourier Domain Optical Coherence Tomography | IOVS | ARVO...
Purpose: : To demonstrate the depth resolved birefringence imaging of retina using polarization sensitive Fourier domain optical coherence tomography system. Methods: : Fiber-based polarization sensitive Fourier domain optical coherence tomography system was developed. Fiber birefringence was compensated with surface reflection from the retina. Phase retardation and orientation of the birefringence can be measured with Jones matrix based algorism in addition to conventional cross sectional OCT. Synchronized two line-CCD cameras allow high-speed measurement of birefringence of retina in vivo. Results: : Retinal phase retardation map was visualized as depth-resolved image. Retinal birefringence tomograph of healthy volunteers were analyzed and compared to earlier literatures; the results of polarization sensitive time domain optical coherence tomography and ...http://iovs.arvojournals.org/article.aspx?articleid=2393146
Download Spectral Domain Optical Coherence Tomography In Macular Diseases
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Reproducibility of high-resolution optical coherence tomography measurements of the nerve fibre layer with the new Heidelberg...
Previous studies have almost exclusively used standard time-domain optical coherence tomography (TD-OCT, Stratus OCT; Carl Zeiss Meditec, Dublin, California) as a non-invasive retinal ocular imaging technique to measure structural changes in the axonal integrity of the retinal nerve fibre layer (RNFL) in patients with glaucoma, various optic neuropathies, optic neuritis (ON) and/or multiple sclerosis (MS).1-3 … ...http://bjo.bmj.com/content/95/6/804
OSA | Spectroscopic phase-dispersion optical coherence tomography measurements of scattering phantoms
We demonstrate a novel technique to determine the size of Mie scatterers with high sensitivity. Our technique is based on spectral domain optical coherence tomography measurements of the phase dispersion that is induced by the scattering process. We use both Mie scattering predictions and dispersion measurements of phantoms to show that the scattering dispersion is very sensitive to small changes in the size and/or refractive index of the scatterer. We also show the light scattered from a single sphere is, in some cases, non-minimum phase. Therefore, the phase is independent of the intensity of the scattered light, and both intensity and phase must be measured directly in order to characterize more completely the scattering problem. Phase dispersion measurements may have application to distinguishing the size and refractive index of scattering particles in biological tissue samples.. ©2006 Optical Society of America. Full Article , PDF ...https://www.osapublishing.org/oe/abstract.cfm?uri=oe-14-18-8138
Optical coherence tomography measurements of the fresh porcine eye and response of the outer coats of the eye to volume...
Asejczyk-Widlicka, Magdelena, Schachar, Ronald A. and Pierscionek, Barbara K. (2008) Optical coherence tomography measurements of the fresh porcine eye and response of the outer coats of the eye to volume increase. Journal of Biomedical Optics, 13(2), 024002. ISSN (print) 1083-3668 ...http://eprints.kingston.ac.uk/22415/
Global Optical Coherence Tomography Market is Projected to Post a Remarkable CAGR of 10.9% over the forecast period | Bismarck...
Optical Coherence Tomography Market: Global Historical Growth (2012-2016) & Future Outlook (2017-2024) Demand Analysis & Opportunity Evaluation". The global optical coherence tomography market is segmented into application such as ophthalmology, dermatology, oncology, cardiovascular, dentistry and cancer detection. Among these segments, ophthalmology segment is expected to occupy the top position in overall optical coherence tomography market. Further, the growth of this segment is attributed to various factors such as increasing number of patients affected with eyes disorders such as age-related macular degeneration, diabetic retinopathy, macular edema and others. Apart from this, dermatology segment mask an outstanding CAGR in near future owing to growing skin disorders and continuous technological advancement in the field of optical ...http://www.bismarcknewsupdates.com/story/158778/global-optical-coherence-tomography-market-is-projected-to-post-a-remarkable-cagr-of-109-over-the-forecast-period.html
Optical coherence tomography legal definition of Optical coherence tomography
Definition of Optical coherence tomography in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is Optical coherence tomography? Meaning of Optical coherence tomography as a legal term. What does Optical coherence tomography mean in law?http://legal-dictionary.thefreedictionary.com/Optical+coherence+tomography
A randomized optical coherence tomography study of coronary stent strut coverage and luminal protrusion with rapamycin-eluting...
OBJECTIVES: We used optical coherence tomography, which has a resolution of |20 microm, to analyze thin layers of neointima in rapamycin-eluting coronary stents. BACKGROUND: Lack of neointimal coverage has been implicated in the pathogenesis of drug-eluting coronary stent thrombosis. Angiography and intracoronary ultrasound lack the resolution to examine this. METHODS: We conducted a randomized trial in patients receiving polymer-coated rapamycin-eluting stents (Cypher, Cordis, Johnson & Johnson, Miami, Florida) and nonpolymer rapamycin-eluting stents (Yukon, Translumina, Hechingen, Germany) to examine neointimal thickness, stent strut coverage, and protrusion at 90 days. Twenty-four patients (n = 12 for each group) underwent stent deployment and invasive follow-up at 90 days with optical coherence tomography. The primary end point was binary stent strut coverage. Coprimary end points were neointimal ...https://www.rdm.ox.ac.uk/publications/105071
OSA | Bidirectional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities in human...
We describe a bidirectional color Doppler Fourier-domain optical coherence tomography system capable of measuring absolute velocities of moving scatterers by illuminating the sample with two linearly and orthogonally polarized beams, incident at a known angle on the sample. The velocity calculation is independent of the exact orientation of the velocity vector in the detection plane. First measurements were performed on a rotating disk driven at well-defined velocities and tilted by various small angles. Our results indicate a high correlation between preset and calculated velocities (correlation coefficient 0.999) and the independency of these velocities from the tilting angle of the disk. We demonstrate that bidirectional color Doppler optical coherence tomography allows for the measurement of absolute blood flow values in vivo in human retinal vessels.. © 2008 Optical Society of America. ...https://www.osapublishing.org/vjbo/abstract.cfm?uri=ol-33-24-2967
Imaging choroidal neovascular membrane using en face swept-source opti | OPTH
Imaging choroidal neovascular membrane using en face swept-source optical coherence tomography angiography Magdy Moussa,1,2 Mahmoud Leila,3 Hagar Khalid1,2 1Ophthalmology Department, Faculty of Medicine, Tanta University, Tanta, Egypt; 2MEDIC Eye Center, Tanta, Egypt; 3Retina Department, Research Institute of Ophthalmology, Giza, Egypt Purpose: The aim of this study was to assess the efficacy of swept-source optical coherence tomography angiography (SS-OCTA) in delineating the morphology of choroidal neovascular membrane (CNV). Patients and methods: This was a retrospective observational case series reviewing clinical data and fundus fluorescein angiography (FFA), swept-source optical coherence tomography (SS-OCT), and SS-OCTA images of patients with CNV and comparing the findings. The swept-source technology enables deeper penetration and superior axial ...https://www.dovepress.com/imaging-choroidal-neovascular-membrane-using-en-face-swept-source-opti-peer-reviewed-article-OPTH
Clustering of Combined 24-2 and 10-2 Visual Field Grids and Their Relationship With Circumpapillary Retinal Nerve Fiber Layer...
Purpose: The purpose of this study was to cluster the test points of the combined 24-2 and 10-2 visual fields (VFs) and circumpapillary retinal nerve fiber layer thickness (cpRNFLT) sectors using explanatory factor analyses (EFAs). The correlations between the VF clusters and cpRNFLT clusters were determined, and a new function-structure relationship map was determined. Methods: Two hundred fifty-four eyes of 166 subjects (13 normal eyes and 241 eyes with glaucoma) were studied retrospectively. All eyes had an axial length ,27 mm and had undergone 24-2 and 10-2 VF tests using the Swedish Interactive Threshold Algorithm (SITA-standard) and cpRNFLT examinations by spectral domain optical coherence tomography within a 3-month period. Explanatory factor analysis was performed to group the 116 test points of the combined 24-2/10-2 VF test grids into a smaller number of VF clusters. Another EFA was performed to cluster the 24 cpRNFLT sectors. The correlations ...http://iovs.arvojournals.org/article.aspx?articleid=2529380
OSA | High-precision, high-accuracy ultralong-range swept-source optical coherence tomography using vertical cavity surface...
We demonstrate ultralong-range swept-source optical coherence tomography (OCT) imaging using vertical cavity surface emitting laser technology. The ability to adjust laser parameters and high-speed acquisition enables imaging ranges from a few centimeters up to meters using the same instrument. We discuss the challenges of long-range OCT imaging. In vivo human-eye imaging and optical component characterization are presented. The precision and accuracy of OCT-based measurements are assessed and are important for ocular biometry and reproducible intraocular distance measurement before cataract surgery. Additionally, meter-range measurement of fiber length and multicentimeter-range imaging are reported. 3D visualization supports a class of industrial imaging applications of OCT.. © 2013 Optical Society of America. Full Article , PDF Article ...https://www.osapublishing.org/ol/abstract.cfm?uri=ol-38-5-673
OSA | Experimental demonstration of high-speed full-range Fourier domain optical coherence tomography imaging using...
phase-shifting algorithm, removing unwanted components becomes possible, including dc and autocorrelation terms, from the interferogram. This method doubles the measurement range. In other words, this approach enables one-shot and full-range FD-OCT. Experimental results show that the reconstruction parameters of the sample are close to the conventional time-domain optical coherence tomography.. © 2012 Optical Society of America. Full Article , PDF Article ...https://www.osapublishing.org/vjbo/abstract.cfm?URI=ao-51-36-8762
Differences of Intrasession Reproducibility of Circumpapillary Total Retinal Thickness and Circumpapillary Retinal Nerve Fiber...
Purpose To evaluate the intrasession reproducibility of various thickness parameters used to diagnose and follow-up glaucoma, in particular circumpapillary total retinal thickness (cpTR) provided by the RS-3000 optical coherence tomograph (OCT). Methods Fifty-three healthy eyes of 28 subjects underwent three consecutive imaging with the RS-3000 Advance OCT (NIDEK, Aichi,Japan) to evaluate the intrasession reproducibility of circumpapillary total retinal thickness (cpTR), circumpapillary retinal nerve fiber layer thickness (cpRNFL), macular ganglion cell complex thickness (mGCC) and macular total retina thickness (mTR) measurements. Intraclass correlation (ICC), coefficient of variation (CV) and reproducibility coefficient (RC) were calculated for each parameter. Results The ICC and CV values for mean cpTR and cpRNFL were 0.987 and 0.897, and 0.60% and 2.81%, respectively. The RC values for the mean cpTR and cpRNFL were 5.95 μm and 9.04 μm, respectively. For all cpTR ...http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144721
OSA | Simultaneous swept source optical coherence tomography of the anterior segment and retina using coherence revival
We report on an implementation of coherence revival-based heterodyne swept source optical coherence tomography that is capable of simultaneously imaging the anterior and posterior eye. A polarization-encoded sample arm was used to efficiently focus orthogonal polarizations on the anterior segment and retina. Depth encoding was achieved using coherence revival, which allows for multiple depths within a sample to be simultaneously imaged and frequency encoded by carefully controlling the optical pathlength of each sample path. This design is a significant step toward whole-eye optical coherence tomography (OCT), which would enable customized ray-traced modeling of patient eyes to improve refractive surgical interventions and eliminate optical artifacts in retinal OCT diagnostics. We demonstrated the feasibility of this system for in vivo ...https://www.osapublishing.org/ol/abstract.cfm?uri=ol-37-11-1883
Optical Coherence Tomography Market 2017 New Era of Healthcare Industry Growing at Staggering a CAGR of 8.2% by 2023 -...
The Worldwide Optical Coherence Tomography Market is growing with the rapid pace; mainly due the burgeoning Healthcare Sector. According to a recent study report published by the Market Research Future, The World Optical Coherence Tomography Market is booming and expected to gain prominence over the forecast period. The Market is forecasted to demonstrate a huge growth by 2023, surpassing its previous growth records in terms of value & volume. The World Market research report of Optical Coherence Tomography is expected to reach US$ 1.59 billion in 2023 from US$ 0.14 billion in 2016 with a CAGR of approximately 8.2% during the forecast period 2017-2023.. Market Research Future published new report, titled "Optical Coherence Tomography Market -Research Report: Forecast to 2023".. Some of the Key Players in ...http://www.abnewswire.com/pressreleases/optical-coherence-tomography-market-2017-new-era-of-healthcare-industry-growing-at-staggering-a-cagr-of-82-by-2023_158522.html
Optical Coherence Tomography Market 2017 New Era of Healthcare Industry Growing at Staggering a CAGR of 8.2% by 2023 | Cheyenne...
The Worldwide Optical Coherence Tomography Market is growing with the rapid pace; mainly due the burgeoning Healthcare Sector. According to a recent study report published by the Market Research Future, The World Optical Coherence Tomography Market is booming and expected to gain prominence over the forecast period. The Market is forecasted to demonstrate a huge growth by 2023, surpassing its previous growth records in terms of value & volume. The World Market research report of Optical Coherence Tomography is expected to reach US$ 1.59 billion in 2023 from US$ 0.14 billion in 2016 with a CAGR of approximately 8.2% during the forecast period 2017-2023.. Market Research Future published new report, titled "Optical Coherence Tomography Market -Research Report: Forecast to 2023".. Some of the Key Players in ...http://www.cheyennejournal.com/story/151671/optical-coherence-tomography-market-2017-new-era-of-healthcare-industry-growing-at-staggering-a-cagr-of-82-by-2023.html
Intravascular Optical Coherence Tomography (OCT) Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast,...
The development of high-resolution and high-speed OCT technology as well as OCT compatible catheter/endoscopes and other delivery systems represent the future of OCT imaging clinical applications. The unique capabilities of OCT imaging make it an ideal choice for the diagnosis and clinical management of many diseases. In 2015, the total revenue of the intravascular OCT market was $128 million; it increased to $140 million in 2016. The primary factors contributing in the growth of the Optical Coherence Tomography (OCT) market is growing aging population and extensive application scope of the technology. Moreover, technological benefits of OCT such as ability to visualize in-depth structures of the eye, mucosal membranes, surface tissues and vascular systems; is significantly driving the growth of the Optical Coherence Tomography (OCT) market. Furthermore, extensive use of OCT devices in drug discovery and ...http://sacinsight.com/report/intravascular-optical-coherence-tomography-oct-market-global-industry-analysis-size-share-growth-trends-forecast-2016-2023/
The Feasibility of Spectral-Domain Optical Coherence Tomography Grading of Anterior Chamber Inflammation in a Rabbit Model of...
Anterior chamber inflammation is currently measured and graded by clinical examination using slit-lamp biomicroscopy and the SUN scale. This approach is considered the gold-standard for clinical diagnosis, where aqueous sampling cannot be easily obtained. This study investigates an alternative method for grading inflammatory cells within the anterior chamber using SD-OCT, a technology already being used in clinical settings. Spectral-domain optical coherence tomography allows for the noninvasive capture of cross-sectional image frames where cells can be visualized as reflective spots. Our data show that SD-OCT counts correlated with aqueous cell counts better than the correlation between SUN grading and aqueous cell counts. Spectral-domain optical coherence tomography has known limitations, however. The axial resolution of SD-OCT is approximately 5 μm, and the transverse resolution is approximately 20 μm. ...http://iovs.arvojournals.org/article.aspx?articleid=2535986
Optical Coherence Tomography Measurements in Eyes With Band Atrophy - Full Text View - ClinicalTrials.gov
The study is designed to evaluate the ability of optical coherence tomography and VCC scanning laser polarimetry to measure and identify the pattern of band atrophy of the optic nerve in patients with long standing chiasmal lesions. The hypothesis is that these new technologies are able to identify such pattern. The idea is that by using eyes with band atrophy one is able to investigate the ability of the new technologies in measuring the retinal nerve fiber layer particularly in the nasal and temporal portions of the optic nerve ...https://clinicaltrials.gov/ct2/show/NCT00395122
Looking into supraciliary space with anterior segment optical coherence Tomography | IOVS | ARVO Journals
Purpose : To demonstrate the usefulness of anterior segment optical coherence tomography (OCT) to identify the supraciliary space easily. Methods : Anterior segment OCT (Visante® Optical Coherence Tomography, Carl Zeiss Meditec Inc.,Dublin, CA, USA) was performed in 10 eyes of 7 patients suspected of supraciliary effusion or cyclodialysis cleft. At the time of OCT, The eyeball was moved clockwise, and the estimating line was adjusted to include the 1/3 cornea and 2/3 sclera on the basis of the limbus of the cornea and measured perpendicular to the limbus. And included more than two directions. When the cyclodialysis cleft was suspected, the range of 12 hours was measured at intervals of one hour to determine the range. Results : After argon laser peripheral iridoplasty (ALPI), intraocular pressure was adjusted to less than 10 mmHg, but supracilliary effusion was observed in 2 eyes of 2 patients with ...http://iovs.arvojournals.org/article.aspx?articleid=2639769
Combined depth imaging technique on spectral-domain optical coherence tomography | Archivio Istituzionale della Ricerca
Purpose: To describe a technique to obtain combined images of vitreoretinal and choroidal structures using spectral-domain (SD) optical coherence tomography (OCT) and to evaluate applicability in normal eyes and limitations in eyes with cataract. Design: Prospective, observational case series. Methods: Three different foveal scans, including conventional SD OCT, enhanced depth imaging OCT and the novel method called combined depth imaging (CDI) OCT, were obtained in 42 eyes of healthy volunteers and in 26 eyes with cataract using the Heidelberg Spectralis HRA (Heidelberg Engineering). The CDI OCT images were obtained manually using an image modification process that enhances the vitreoretinal interface first and then the choroid, while averaging 100 separate OCT scans. The visualization of the inner border of the preretinal pocket and the outer border of the choroid was graded by independent masked observers for each OCT scan method. Results: The CDI ...https://air.unimi.it/handle/2434/231982
OSA | Polarization Sensitive Optical Coherence Tomography
Fully fiber based polarization sensitive Spectral/Fourier Domain Optical Coherence Tomography (PS-SD/FD-OCT) will be presented that allows for high speed characterization of tissue polarization properties including relative optic axis orientation, birefringence, and diattenuation. Quantification of retinal nerve fiber layer and skin collagen birefringence will be demonstrated using the SD/FD-OCT approach.. © 2005 Optical Society of America. PDF Article ...https://www.osapublishing.org/abstract.cfm?uri=FiO-2005-FWA6
Effects of Age on Optical Coherence Tomography Measurements of Healthy Retinal Nerve Fiber Layer, Macula and Optic Nerve Head
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.http://pubmedcentralcanada.ca/pmcc/articles/PMC2747246/
Comparison of retinal thickness using Spectral Domain Optical Coherence Tomography (SD-OCT) in diabetic subjects compared to...
Purpose: : Neuronal changes are thought to precede microvascular changes in diabetes. So this study compared retinal thickness (RT) in diabetic subjects compared to controls in a multiethnic cohort using Spectral Domain Optical Coherence Tomography (SD-OCT). Methods: : This is a retrospective study on 72 diabetic subjects (with no or minimal retinopathy) and 46 normal subjects. Subjects were from three ethnic groups (Asian, Afro-Caribbean and Caucasian); with age range 20-86 years and best corrected visual acuity 20/20 or better. The OCT scans were performed using a standard protocol on the Heidelberg Spectralis SD-OCT as part of routine medical care. Retinal thickness (RT) in 9 Early Treatment Diabetic Retinopathy Study (ETDRS) subfields, including central subfield was compared between the two groups after adjusting for age, gender and ethnicity. Results: : There is no difference in mean retinal thickness between diabetics and non-diabetics after adjusting ...http://iovs.arvojournals.org/article.aspx?articleid=2350219