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*  Toll-like receptor 7/8 | Disease Models & Mechanisms
Muneer G. Hasham, Nicoleta Baxan, Daniel J. Stuckey, Jane Branca, Bryant Perkins, Oliver Dent, Ted Duffy, Tolani S. Hameed, Sarah E. Stella, Mohammed Bellahcene, Michael D. Schneider, Sian E. Harding, Nadia Rosenthal, Susanne Sattler ...
http://dmm.biologists.org/keyword/toll-receptor-78
*  Activation of anti-hepatitis C virus responses via Toll-like receptor 7 | PNAS
Toll-like receptor;. IKK,. IκB kinase;. IRF,. IFN regulatory factor;. DNA-PK,. DNA-dependent protein kinase;. SM360320,. 9- ... Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Jongdae Lee, Christina C. N. Wu, Ki Jeong Lee, Tsung- ... Here we present evidence showing that a ligand of Toll-like receptor 7 (TLR7) can induce anti-HCV immunity not only by IFN ... Impaired Toll-Like Receptor 3-Mediated Immune Responses from Macrophages of Patients Chronically Infected with Hepatitis C ...
https://www.pnas.org/content/103/6/1828?ijkey=73b13d5858a2aaa461ff36a43b79a2982c9c8ebe&keytype2=tf_ipsecsha
*  TLR7 - Toll-like receptor 7 precursor - Homo sapiens (Human) - TLR7 gene & protein
TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to ... toll-like receptor 9 signaling pathway Source: Reactome. *toll-like receptor signaling pathway Source: GO_CentralInferred from ... Toll-like receptor 7Add BLAST. 1023. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical view. ... toll-like receptor 7 signaling pathway Source: GO_CentralInferred from biological aspect of ancestori*21873635 ...
https://www.uniprot.org/uniprot/Q9NYK1
*  Reactome | Toll Like Receptor 7/8 (TLR7/8) Cascade
Toll-like Receptor Cascades (Homo sapiens) * Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens) ... Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8 Heil, F, Hemmi, H, Hochrein, H, Ampenberger ... Toll Like Receptor 7/8 (TLR7/8) Cascade (Dictyostelium discoideum) Toll Like Receptor 7/8 (TLR7/8) Cascade (Drosophila ... Toll Like Receptor 7/8 (TLR7/8) Cascade (Saccharomyces cerevisiae) Toll Like Receptor 7/8 (TLR7/8) Cascade (Schizosaccharomyces ...
http://www.reactome.org/content/detail/R-HSA-168181
*  Modulators of Toll-like Receptors -7 and -8
Toll-like receptors (TLR)-7/-8 are innate immune receptors present in the endosomal compartment that are activated by single- ...
https://kuscholarworks.ku.edu/handle/1808/8186
*  Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus | PNAS
Located at Xp22.2, Toll-like receptor 7 (TLR7; OMIM no. 300365) and its functionally related gene TLR8 (OMIM no. 300366) encode ... 2009) Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1. Nat Med 15:955-959. ... 2006) Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a ... Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus. Nan Shen, Qiong Fu, ...
http://www.pnas.org/content/107/36/15838
*  Discovery of Imidazoquinolines with Toll-Like Receptor 7/8 Independent Cytokine Induction
toll-like receptor. NF-κB. nuclear factor κ light-chain enhancer of activated B cells. ssRNA. single-stranded ribonucleic acid ... Discovery of Imidazoquinolines with Toll-Like Receptor 7/8 Independent Cytokine Induction. Ce Shi,†. Zhengming Xiong,‡. Padmaja ... Toll-like receptors 7 and 8 (TLR 7/8) are key targets for the design of small molecule immunomodulators for use as vaccine ... Toll-like receptors (TLRs) are key targets in the design of immunomodulating agents for use as vaccine adjuvants and anticancer ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC3402226/?lang=en-ca
*  Toll-like Receptor-7 Tolerizes Malignant B Cells and Enhances Killing by Cytotoxic Agents | Cancer Research
Toll receptors. Introduction. Toll-like receptors (TLR) regulate innate and adaptive immunity ( 1), and the identification of ... Toll-like Receptor-7 Tolerizes Malignant B Cells and Enhances Killing by Cytotoxic Agents. Yonghong Shi, Dionne White, Liwei He ... Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein. J Leukoc Biol 2004; 76: 904-8. ... Chronic activation through Toll-like receptors (TLR) occurs in a number of pathologic settings, but has not been studied to the ...
http://cancerres.aacrjournals.org/content/67/4/1823?ijkey=e7ffcbd3d29e2d2bc8aaffc815c0ee52e261dbae&keytype2=tf_ipsecsha
*  Frontiers | Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation via Toll-Like...
... including Toll-like receptor 7 (TLR7). Downstream of viral recognition natural killer (NK) cells are activated as part of the ... including Toll-like receptor 7 (TLR7). Downstream of viral recognition natural killer (NK) cells are activated as part of the ... Keywords: influenza A virus, natural killer cells, pathogen-recognition receptors, Toll-like receptor 7, innate immunity, ... through different pathogen-recognition receptors including Toll-like receptor 7 (TLR7). Downstream of viral recognition natural ...
https://www.frontiersin.org/articles/10.3389/fimmu.2018.00245/full
*  Abstract 14299: MicroRNAs are Released During Myocardial Ischemia Reperfusion Injury and Induce Inflammation via Toll-like...
MicroRNAs are Released During Myocardial Ischemia Reperfusion Injury and Induce Inflammation via Toll-like Receptor 7 in vitro ... MicroRNAs are Released During Myocardial Ischemia Reperfusion Injury and Induce Inflammation via Toll-like Receptor 7 in vitro ... MicroRNAs are Released During Myocardial Ischemia Reperfusion Injury and Induce Inflammation via Toll-like Receptor 7 in vitro ... MicroRNAs are Released During Myocardial Ischemia Reperfusion Injury and Induce Inflammation via Toll-like Receptor 7 in vitro ...
http://circ.ahajournals.org/content/134/Suppl_1/A14299
*  The 2′-O-methylation status of a single guanosine controls transfer RNA-mediated Toll-like receptor 7 activation or inhibition ...
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science. 303:1526-1529. doi:10.1126/science ... Intracellular toll-like receptors. Immunity. 32:305-315. doi:10.1016/j.immuni.2010.03.012. ... Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and ... The 2′-O-methylation status of a single guanosine controls transfer RNA-mediated Toll-like receptor 7 activation or inhibition ...
http://jem.rupress.org/content/209/2/235
*  FRI0029 IL-7-driven T cell activation and toll-like receptor 7 triggering cause additive B cell activation that is further...
IL-7/TLR7A; 9.3±1.4% vs. 33.4±7.3%) and T cell proliferation (IL-7 vs. IL-7/TLR7A; 0.8±0.1% vs. 29.2±5.2%), which for B cells ... However, in the presence of T cells, IL-7 activated both T and B cells (Ki67+ CD4 cells from 1.1±0.2% to 14.4±3.7%, p,0.01 and ... IL-7/TLR7A; 30.2±8.9% vs. 63.0±8.0%). Similar results were observed for activation marker expression on B cells (CD19, HLA-DR ... FRI0029 IL-7-driven T cell activation and toll-like receptor 7 triggering cause additive B cell activation that is further ...
http://ard.bmj.com/content/71/Suppl_3/319.2
*  Cytokines Induced by a Toll-Like Receptor 7 Agonist Potently Inhibit HBV RNA, DNA, and Antigen Levels in Primary Human...
Cytokines Induced by a Toll-Like Receptor 7 Agonist Potently Inhibit HBV RNA, DNA, and Antigen Levels in Primary Human ... Background & Aims: GS-9620, an oral agonist of toll-like receptor 7 (TLR7), is in phase 2 trials for the treatment of chronic ... AASLD 2014 Nov 7-11 Boston. Congrong Niu, Stephane Daffis, Mei Yu, Guofeng Cheng, William E. Delaney IV, Simon P. Fletcher. ... with rebound still incomplete 7 days after removal of TLR7-CM (day 20). A survey of cytokines in TLR7-CM identified recombinant ...
http://www.natap.org/2014/AASLD/AASLD_139.htm
*  Toll-Like Receptor 7 Ligand II | TLR7 Ligand | Buy Toll-Like Receptor 7 Ligand II from Supplier AdooQ®
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*  An exploratory study of systemic administration of the toll-like receptor-7 agonist 852A in patients with refractory metastatic...
PURPOSE: A topical Toll-like receptor 7 (TLR7) agonist induces regression of cutaneous melanocytic neoplasms. We explored ... PURPOSE: A topical Toll-like receptor 7 (TLR7) agonist induces regression of cutaneous melanocytic neoplasms. We explored ... An exploratory study of systemic administration of the toll-like receptor-7 agonist 852A in patients with refractory metastatic ... An exploratory study of systemic administration of the toll-like receptor-7 agonist 852A in patients with refractory metastatic ...
http://www.zora.uzh.ch/id/eprint/13924/
*  Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A...
Toll-like receptor 7 (TLR7) is a pattern recognition receptor that recognizes viral RNA following endocytosis of the virus and ... Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A ...
http://flu.org.cn/en/article-14225.html
*  Expression of Toll-Like Receptors 3, 7, and 9 in Peripheral Blood Mononuclear Cells from Patients with Systemic Lupus...
G. Guggino, A. R. Giardina, F. Ciccia, G. Triolo, F. Dieli, and G. Sireci, "Are toll-like receptors and decoy receptors ... The results of experimental studies point to the involvement of innate immunity receptors-toll-like receptors (TLR)-in the ... "Estrogen receptor alpha modulates Toll-like receptor signaling in murine lupus," Clinical Immunology, vol. 144, pp. 1-12, 2012. ... S. Akira, "Mammalian Toll-like receptors," Current Opinion in Immunology, vol. 15, no. 1, pp. 5-11, 2003. View at Publisher · ...
https://www.hindawi.com/journals/mi/2014/381418/
*  Loss of Toll-like receptor 7 alters cytokine production and protects against experimental cerebral malaria | Malaria Journal |...
This study sought to clarify the role of Toll-like receptors (TLRs) in promoting immunopathology associated with cerebral ... Toll-like receptors (TLRs) are a family of innate immune sensors that are prime candidates for initiating immune responses that ... Fukui R, Saitoh S, Matsumoto F, Kozuka-Hata H, Oyama M, Tabeta K, Beutler B, Miyake K: Unc93B1 biases Toll-like receptor ... Griffith JW, O'Connor C, Bernard K, Town T, Goldstein DR, Bucala R: Toll-like receptor modulation of murine cerebral malaria is ...
https://malariajournal.biomedcentral.com/articles/10.1186/1475-2875-13-354
*  Characterisation of Toll-like receptors 4, 5 and 7 and their genetic variation in the grey partridge | SpringerLink
Toll-like receptors (TLRs) are a cornerstone of vertebrate innate immunity. In this study, we identified orthologues of TLR4, ... The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor. Nature 456:658-662. doi: 10.1038/ ... Molecular cloning and functional characterization of chicken Toll-like receptors-a single chicken toll covers multiple ... Brownlie R, Allan B (2011) Avian Toll-like receptors. Cell Tissue Res 343:121-130. doi: 10.1007/s00441-010-1026-0 PubMed ...
https://link.springer.com/article/10.1007%2Fs10709-015-9819-4
*  Boston Biomedical Announces First Patient Dosed with Investigational Toll-like Receptor (TLR) 7 Agonist DSP-0509 in Phase 1...
Boston Biomedical Announces First Patient Dosed with Investigational Toll-like Receptor (TLR) 7 Agonist DSP-0509 in Phase 1 ... DSP-0509 is an investigational synthetic Toll-like receptor (TLR) 7 agonist. In preclinical models, DSP-0509 was shown to ... Boston Biomedical Announces First Patient Dosed with Investigational Toll-like Receptor (TLR) 7 Agonist DSP-0509 in Phase 1 ... Boston Biomedical Announces First Patient Dosed with Investigational Toll-like Receptor (TLR) 7 Agonist DSP-0509 in Phase 1 ...
https://www.pharmiweb.com/PressReleases/pressrel.asp?row_id=289921
*  buy Toll-Like Receptor 7 Ligand II | Small molecule inhibitors of HCV replication
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*  The impact of imiquimod, a Toll-like receptor-7 ligand (TLR7L), on the immunogenicity of melanoma peptide vaccination with...
To induce local DC maturation, 8 of the vaccinated patients had imiquimod, a Toll-like receptor-7 ligand (TLR7L), applied ... The impact of imiquimod, a Toll-like receptor-7 ligand (TLR7L), on the immunogenicity of melanoma peptide vaccination with ... The impact of imiquimod, a Toll-like receptor-7 ligand (TLR7L), on the immunogenicity of melanoma peptide vaccination with ... The impact of imiquimod, a Toll-like receptor-7 ligand (TLR7L), on the immunogenicity of melanoma peptide vaccination with ...
http://cancerimmunolres.aacrjournals.org/content/canimmarch/4/1/9
*  Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance | Lupus Science & Medicine
Association study of Toll-like receptor 5 (TLR5) and Toll-like receptor 9 (TLR9) polymorphisms in systemic lupus erythematosus ... Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J Exp Med 2005;202:321-31.doi:10.1084/jem. ... Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice. PLoS One 2017;12:e0173471.doi:10.1371/journal.pone. ... Genetic variation in toll-like receptor 9 and susceptibility to systemic lupus erythematosus. Arthritis Rheum 2006;54:1279-82. ...
https://lupus.bmj.com/content/5/1/e000259
*  High Quality Toll-Like Receptor 7 Polyclonal Antibody Best Price For Sale - Manufacturer, Supplier, Exporter
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*  A protective role for toll-like receptor 3 but not toll-like receptor 7 in intimal hyperplasia - Nuffield Department of...
A protective role for toll-like receptor 3 but not toll-like receptor 7 in intimal hyperplasia Share Share Share Share ... A protective role for toll-like receptor 3 but not toll-like receptor 7 in intimal hyperplasia ...
https://www.ndorms.ox.ac.uk/publications/236503