... which is a negative regulator of Toll-like receptor and IL-1 receptor signalling. ... In addition, we are using next generation sequencing technologies to investigate the role of TNF receptor signalling in ... Specifically, our current research is focussed on understanding the regulatory pathways activated by TNF receptor signalling, ... Selective tumor necrosis factor receptor I blockade is antiinflammatory and reveals immunoregulatory role of tumor necrosis ...