TNF-Related Apoptosis-Inducing Ligand | Harvard Catalyst Profiles | Harvard Catalyst
TNF-Related Apoptosis-Inducing Ligand*TNF-Related Apoptosis-Inducing Ligand. *Apoptosis-Inducing Ligand, TNF-Related ... "TNF-Related Apoptosis-Inducing Ligand" by people in Harvard Catalyst Profiles by year, and whether "TNF-Related Apoptosis- ... It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The ... Below are MeSH descriptors whose meaning is related to "TNF-Related Apoptosis-Inducing Ligand". ...https://connects.catalyst.harvard.edu/Profiles/display/Concept/TNF-Related%20Apoptosis-Inducing%20Ligand
Relation of TNF-related Apoptosis-inducing Ligand (TRAIL) Receptor and FLICE-inhibitory Protein Expression to TRAIL-induced...
Thomas W. D., Hersey P. TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells ... 4 The abbreviations used are: TNF, tumor necrosis factor; FasL, Fas ligand; TRAIL, TNF-related apoptosis-inducing ligand; TRAIL ... Relation of TNF-related Apoptosis-inducing Ligand (TRAIL) Receptor and FLICE-inhibitory Protein Expression to TRAIL-induced ... Relation of TNF-related Apoptosis-inducing Ligand (TRAIL) Receptor and FLICE-inhibitory Protein Expression to TRAIL-induced ...http://cancerres.aacrjournals.org/content/59/11/2747?ijkey=3df10ab89d738b3f0e89d810201bcf9b339ef927&keytype2=tf_ipsecsha
Effects of TNF-related apoptosis-inducing ligand on an animal model of type 2 diabetes - EprintsUnife
Effects of TNF-related apoptosis-inducing ligand on an animal model of type 2 diabetes ... 2014) Effects of TNF-related apoptosis-inducing ligand on an animal model of type 2 diabetes. PhD Thesis , Università degli ... Background and aim of the study: Tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) has recently been shown ... TRAIL reversed the changes in substrate utilization induced by HFD and ameliorated skeletal muscle free fatty acids oxidation ...http://eprints.unife.it/963/
RGD-avidin-biotin pretargeting to αvβ₃ integrin enhances the proapoptotic activity of TNFα related apoptosis inducing ligand ...
Recombinant TNF-related apoptosis-inducing ligand (TRAIL) is considered a powerful and selective inducer of tumor cell death. ... RGD-avidin-biotin pretargeting to αvβ₃ integrin enhances the proapoptotic activity of TNFα related apoptosis inducing ligand ( ... RGD-avidin-biotin pretargeting to αvβ₃ integrin enhances the proapoptotic activity of TNFα related apoptosis inducing ligand ( ... The assembled complexes killed tumor cells (Jurkat T cells) via apoptosis induction. Furthermore, we demonstrated that the ...https://dspace.library.uu.nl/handle/1874/30507
Publications of Faculty of Medicine: SERUM SOLUBLE TNF-RELATED APOPTOSIS-INDUCING LIGAND (TRAIL) IN PATHOGENESIS OF SYSTEMIC...
SERUM SOLUBLE TNF-RELATED APOPTOSIS-INDUCING LIGAND (TRAIL) IN PATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS , Author: Shereen ... SERUM SOLUBLE TNF-RELATED APOPTOSIS-INDUCING LIGAND (TRAIL) IN PATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS ... Publications of Faculty of Medicine: SERUM SOLUBLE TNF-RELATED APOPTOSIS-INDUCING LIGAND (TRAIL) IN PATHOGENESIS OF SYSTEMIC ...http://bu.edu.eg/medicine_publications/1091
TNF-related apoptosis-inducing ligand (TRAIL) holds promise for treatment of cancer credited - Role of adrenergic receptors in...
TNF-related apoptosis-inducing ligand (TRAIL) holds promise for treatment of cancer credited. January 25, 2018. TNF-related ... apoptosis-inducing ligand (TRAIL) holds promise for treatment of cancer credited to its ability to selectively kill cancer ... FACS Evaluation of Apoptosis with Annexin Sixth is v/Propidium Iodide Labels MCF10A cells had been treated with 30 systems/ml ...http://researchreportone.com/?p=4202
Tumor necrosis aspect (TNF)-related apoptosis-inducing ligand (Path) is actually a loss - Targeting the Pim kinases in Cancer
Tumor necrosis aspect (TNF)-related apoptosis-inducing ligand (Path) is actually a loss of life liganda person in the TNF ... Tumor necrosis aspect (TNF)-related apoptosis-inducing ligand (Path) is actually a loss boston February 11, 2019. ... Introduction Path is an associate from the tumor necrosis element superfamily that selectively induces apoptosis in a multitude ... Significant co-morbidities between obesity-related metabolic disease and stress-related emotional disorders suggest ...http://www.bostonscienceandengineeringlectures.com/2019/02/11/tumor-necrosis-aspect-tnf-related-apoptosis-inducing-ligand-path-is-actually-a-loss/
Blood Biomarkers as Outcome Measures in Inflammatory Neurologic Diseases | Springer for Research & Development
Serum TNF-Related Apoptosis-Inducing Ligand. TNF-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily ... TNF-related apoptosis inducing ligand (TRAIL) as a potential response marker for interferon-beta treatment in multiple ... Hilliard B, Wilmen A, Seidel C, Liu TS, Goke R, Chen Y. Roles of TNF-related apoptosis-inducing ligand in experimental ... tumor necrosis factor-related apoptosis-inducing ligand; CHI3L1 = chitinase 3-like-1; Nfl = neurofilament light chain; CHI3L2 ...https://rd.springer.com/article/10.1007/s13311-016-0486-7
Antiproliferative and Cytotoxic Activities | SpringerLink
TNFα. Tumor necrosis factor-α. TRAIL. TNF-related apoptosis-inducing ligand ... Muñoz Acuña U, Shen Q, Ren Y et al (2013) Goyazensolide induces apoptosis in cancer cells in vitro and in vivo. Int J Cancer ... Li H, Li M, Wang G et al (2016) EM23, a natural sesquiterpene lactone from Elephantopus mollis, induces apoptosis in human ... Li Y, Zhang Y, Fu M et al (2012) Parthenolide induces apoptosis and lytic cytotoxicity in Epstein-Barr virus-positive Burkitt ...https://link.springer.com/chapter/10.1007%2F978-3-319-78274-4_13
Autophagic and Apoptotic Effects of HDAC Inhibitors on Cancer Cells
TNF-related apoptosis-inducing ligand. TSA:. Trichostatin-A. XIAP:. X-linked inhibitor of apoptosis protein. ... inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and ... culminating in apoptosis. SAHA and MS275 induced mitochondrial dysfunction and apoptosis through enhanced ROS generation, XIAP ... capable of inducing apoptosis. Nuclear localization of p53 induces autophagy, whereas cytoplasmic accumulation inhibits ...https://www.hindawi.com/journals/bmri/2011/830260/
RCSB PDB for 1DU3
TNF-RELATED APOPTOSIS INDUCING LIGAND D, E, F..., J, K, LD, E, F, J, K, L. 168 Homo sapiens Gene Name(s): TNFSF10 Gene View ... Interactions are determined by geometric criteria as described in K. Stierand, M. Rarey (2010), Drawing the PDB: Protein-ligand ...http://www.rcsb.org/pdb/explore/biologyAndChemistry.do?structureId=1DU3
Immunomodulatory plasticity of mesenchymal stem cells: a potential key to successful solid organ transplantation | SpringerLink
... and expression of inhibitory co-stimulatory molecules such as TNF-related apoptosis-inducing ligand (TRAIL), programmed death ... FAS Ligand)-induced apoptosis [48, 108] and this response is further elevated when apoptotic T cells stimulate macrophage s to ... Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis. Cell Stem Cell. 2012;10(5): ... Galleu A, Riffo-Vasquez Y. Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation. Sci ...https://link.springer.com/article/10.1186/s12967-018-1403-0
Impact of Procyanidins from Different Berries on Caspase 8 Activation in Colon Cancer
... and review articles dealing with the cellular and molecular mechanisms of oxidative stress in the nervous system and related ... TNF-related apoptosis-inducing ligand.. Conflict of Interests. The authors declare that there is no conflict of interests ... blueberry Pcys could as well potentiate TRAIL-induced apoptosis of SW480 cell line and sensitize TRAIL-induced apoptosis on ... by other TNF superfamily death receptors inducing caspases 8 and 9 activation, for example, TNF-R1, DR3, or DR6; further ...https://www.hindawi.com/journals/omcl/2015/154164/
JCI - Standard abbreviations
TNF, tumor necrosis factor. TOF, time-of-flight (MALDI-TOF). TRAIL, TNF-related apoptosis-inducing ligand ...https://www.jci.org/kiosks/publish/abbreviations
Frontiers | Anticancer Potential of Citrus Juices and Their Extracts: A Systematic Review of Both Preclinical and Clinical...
TNF-α, tumor necrosis factor; TRAIL, TNF-related apoptosis-inducing ligand. ... 2014). Bergamot juice extract inhibits proliferation by inducing apoptosis in human colon cancer cells. Anticancer. Agents Med ... In neuroblastoma cells (SH-SY5Y) BJ caused cell cycle arrest in G1 phase without triggering apoptosis, and induced ... Authors demonstrated that the nanovescicles extracted by ultracentrifugating LeJ might induce apoptosis in CML cells by ...https://www.frontiersin.org/articles/10.3389/fphar.2017.00420/full
CD99 Signals Caspase-Independent T Cell Death | The Journal of Immunology
TNF-related apoptosis-inducing ligand (TRAIL) or Apo-2 ligand has recently been cloned (14, 15) and shown to mediate programmed ... activation-induced cell death; TRAIL, TNF-related apoptosis-inducing ligand; DR, death receptor; CHO, Chinese hamster ovary; WT ... faster and more profound death responses as compared with the impact of anti-Fas and TNF-related apoptosis-inducing ligand ( ... Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat. Med. 5: 157. ...http://www.jimmunol.org/content/166/8/4931.long
Frontiers | The Molecular Mechanism of Natural Killer Cells Function and Its Importance in Cancer Immunotherapy | Immunology
TNF-α, tumor necrosis factor-α; TRAIL, TNF-related apoptosis-inducing ligand; Tregs, regulatory T cells. ... Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development. J ... NK cells express TNF receptor ligand-Fas ligand (FasL), TNF, and TRAIL which binds to their corresponding receptor on target ... A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity. Eur J Immunol (2003) 33(2 ...https://www.frontiersin.org/articles/10.3389/fimmu.2017.01124/full
Reciprocal regulation of signaling and endocytosis: Implications for the evolving cancer cell | JCB
A second example derives from dynamin isoform-specific requirements for CME of TRAIL (TNF-related apoptosis-inducing ligand)- ... Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced ... Most ligands dissociate from their receptors in the low-pH environment of the endosome. Dissociated ligands are carried within ... Other cancer-related, mutant p53-dependent mechanisms can enhance receptor recycling to prolong signaling. Thus, during tumor ...http://jcb.rupress.org/content/216/9/2623
Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo | JEM
IFN-I induces the expression of Fas and TNF-related apoptosis-inducing ligand (TRAIL) which, through Fas/FasL and TRAIL/death ... TNF-related apoptosis-inducing ligand. VACV. vaccinia virus. VSV. vesicular stomatitis virus. ... Interferon beta induces mature dendritic cell apoptosis through caspase-11/caspase-3 activation. Blood. 114:1344-1354. doi: ... The BH3-only protein bid is dispensable for DNA damage- and replicative stress-induced apoptosis or cell-cycle arrest. Cell. ...http://jem.rupress.org/content/208/12/2367
CASP6 | Cancer Genetics Web
Lexatumumab, a human agonistic monoclonal antibody against tumor necrosis factor (TNF)-related apoptosis-inducing ligand ... Mechanistic studies demonstrated that XIAP inhibition potentiates p53-induced apoptosis by decreasing p53-induced p21 and that ... apoptosis-related genes, CASP4, CASP6, IGFBP3, and DFFA; ubiquitin proteolysis pathway-related genes, UBE3A and UBE2C; ... Related: Apoptosis ERBB2 (HER2) Stomach Cancer Gastric Cancer Irinotecan Lapatinib (Tyverb) Gefitinib (Iressa) ...http://www.cancerindex.org/geneweb/CASP6.htm
Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer | JEM
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J. Immunol ... BALB/c TNF-related apoptosis-inducing ligand (TRAIL)-deficient (TRAIL−/− ; from J. Peschon, AMGEN; reference 44); and BALB/c ... Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell ... The natural killer T (NKT) cell ligand alpha-galactosylceramide demonstrates its immunopotentiating effect by inducing ...http://jem.rupress.org/content/201/12/1973
Type I Interferon as a Powerful Adjuvant for Monocyte-Derived Dendritic Cell Development and Activity in Vitro and in Hu-Pbl...
Primer sequences for TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors (R1, R2, R3, and R4) are reported ... 1999) Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) J. ... TNF)-related apoptosis-inducing ligand (TRAIL)-expressing DCs endowed with potent functional activities, superior with respect ... to induce a suicide of activated DCs, as suggested by apoptosis induction, and to induce apoptosis of virus-infected or tumor ...http://jem.rupress.org/content/191/10/1777
The role of death receptor ligands in shaping tumor microenvironment.
... activate apoptosis in cells expressing the cognate receptors. Evidence suggests that these ligands also deliver pro- ... 0/Antineoplastic Agents; 0/Fas Ligand Protein; 0/TNF-Related Apoptosis-Inducing Ligand ... But death ligands crosslinking their receptors also induce inhibition of apoptosis and activation of the transcription factor, ... Death receptor ligands (FasL, TRAIL) activate apoptosis in cells expressing the cognate receptors. Evidence suggests that these ...http://www.biomedsearch.com/nih/role-death-receptor-ligands-in/17190648.html
Publikationen - KNHI
TNF-related apoptosis-inducing ligand and its decoy receptor osteoprotegerin in nonischemic dilated cardiomyopathy. Biocem ... Patient- and provider-related determinants of generic and specific health-related quality of life of patients with chronic ... Pulmonary artrial hypertension related to HIV infection: a systematic review of the literature comprising 192 cases. Current ... Investigation of the influence of the socioeconomic status on the health-related quality of life in patients before and after ...http://knhi.de/research/publications/
Recombinant Human sTRAIL Receptor 2 protein (ab643) | Abcam
TNF related apoptosis inducing ligand receptor 2. *TNF-related apoptosis-inducing ligand receptor 2 ... mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. ... Biological Activity : Determined by its ability to inhibit apoptosis induced by Human sTRAIL/Apo2L in LN-18 cells (human ... The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent ...https://www.abcam.com/recombinant-human-strail-receptor-2-protein-ab643.html