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*  Transcriptional activity of tumor necrosis factor-alpha gene in peripheral blood mononuclear cells in patients with coronary...
Transcriptional activity of tumor necrosis factor-alpha gene in peripheral blood mononuclear cells in patients with coronary ... Ageing, tumour necrosis factor-alpha (TNF-alpha) and atherosclerosis. Clin Exp Immunol 2000; 121(2): 255-60. ... Transcriptional activity of gene encoding subunits r1 and r2 of interferon gamma receptor in peripheral blood mononuclear cells ... It has been demonstrated that tumor necrosis factor-alpha (TNF-α) mainly influences the vascular homeostasis and endothelial ...
http://www.arya.mui.ac.ir/index.php/arya/article/view/1491
*  JCI Insight - TNF receptor-activated factor 2 mediates cardiac protection through noncanonical NF-κB signaling
TNF receptor-activated factor 2 mediates cardiac protection through noncanonical NF-κB signaling. ... TNF receptor-activated factor 2 mediates cardiac protection through noncanonical NF-κB signaling. ... To elucidate the mechanisms responsible for cytoprotective effects of TNF receptor-activated factor 2 (TRAF2) in the heart, we ...
https://insight.jci.org/articles/view/98278/figure/4
*  HPMR - rec TRAF2, TNF receptor-associated factor 2
TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB. Arch ... Receptor TRAF2 interacts with: Receptor TNFRSF4 - TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMI ...[read more..]. 4-1BB and Ox40 are ... TRAF2 - TNF RECEPTOR-ASSOCIATED FACTOR 2 Family:TNFNGF Synonyms:TRAP,TRAP3,MGC:45012 External links: Entrez Gene, Omim. ... TNF receptor-associated factor 2 (TRAF2) was identified as an interacting protein in both screens. The ability of both 4-1BB ...
http://www.receptome.org/SearchDB/getGenePage.asp?Param=7186&ProtId=1&ProtType=Receptor
*  中国科学院南海海洋研究所机构知识库(SCSIO OpenIR): A molluscan TNF receptor-associated factor 2 (TRAF2) was involved in host defense
Tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) is a member of the TRAF superfamily that acted as a key signal ... A molluscan TNF receptor-associated factor 2 (TRAF2) was involved in host defense against immune challenges. ... A molluscan TNF receptor-associated factor 2 (TRAF2) was involved in host defense against immune challenges[J]. FISH & ... Qu, FF,Xiang, ZM,Zhou, YL,Qin, YP,&qufufa@163.com.(2018).A molluscan TNF receptor-associated factor 2 (TRAF2) was involved in ...
http://ir.scsio.ac.cn/handle/344004/17041
*  TRAF2 Gene - GeneCards | TRAF2 Protein | TRAF2 Antibody
TNF Receptor Associated Factor 2, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - ... tumor necrosis factor (TNF)- receptor-associated factor,variably expressed in heart,liver,placenta,brain,skeletal muscle,kidney ... TRAF2 (TNF Receptor Associated Factor 2) is a Protein Coding gene. Diseases associated with TRAF2 include Salivary Gland Cancer ... The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=TRAF2
*  Endoplasmic reticulum stress-induced apoptosis in the development of diabetes: is there a role for adipose tissue and liver? |...
These involve death receptors that are members of the tumor necrosis factor (TNF) receptor gene superfamily [23]. The intrinsic ... Locksley RM, Killeen N, Lenardo MJ (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104:487- ... TNF receptor-associated factor-2) and ASK1. This leads to activation of ASK1 and JNK, followed by apoptosis, and (3) activation ... is phosphorylation of the important insulin receptor docking protein insulin receptor protein-1 (IRS-1), whereby ...
https://link.springer.com/article/10.1007%2Fs10495-009-0400-4
*  NF-κB activation-induced anti-apoptosis renders HER2-positive cells drug resistant and accelerates tumor growth. - PubMed -...
... tumor necrosis factor; TRAF2, TNF-receptor activating Factor 2; NFKB1, nuclear factor kappa B 1; and nuclear factor kappa B 2. ... Nuclear factor kappa B activation-induced anti-apoptosis renders HER2 positive cells drug resistant and accelerates tumor ... Nuclear factor kappa B activation-induced anti-apoptosis renders HER2 positive cells drug resistant and accelerates tumor ... Nuclear factor kappa B activation-induced anti-apoptosis renders HER2 positive cells drug resistant and accelerates tumor ...
https://www.ncbi.nlm.nih.gov/pubmed/24319068
*  NF-kappaB Signaling | www.antibodies-online.com
... or heterodimeric transcription factors that are central in... ... nuclear factor kappa-light-chain-enhancer of activated B cells ... TRAF3 (TNF Receptor-Associated Factor 3): TRAF3 antibodies TRAF3 ELISA Kits TRAF3 Proteins ... TRAF5 (TNF Receptor-Associated Factor 5): TRAF5 antibodies TRAF5 ELISA Kits TRAF5 Proteins ... TRAF6 (TNF Receptor-Associated Factor 6): TRAF6 antibodies TRAF6 ELISA Kits TRAF6 Proteins ...
https://www.antibodies-online.com/nf-kappab-signaling-pathway-5/
*  Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy
... and clinical studies related to type 1 and type 2 diabetes. The journal welcomes submissions focusing on the epidemiology, ... TNF-α: tumor necrosis factor alpha; IL-1R1: interleukin 1 receptor type 1; TNFR-1: tumor necrosis factor receptor 1; DD: death ... TNF receptor-associated factor 6; NEMO: nuclear factor kappa B essential modulator; IKK: inhibitor of nuclear factor kappa B ... tumor necrosis factor receptor type 1-associated death domain protein; TRAF2: TNF receptor-associated factor 2; DISC: death ...
https://www.hindawi.com/journals/jdr/2018/9601801/
*  GO Gene List
TNF receptor-associated factor 2. NM_021138. Gene Info. TRAF6. TNF receptor-associated factor 6, E3 ubiquitin protein ligase. ... Tumor necrosis factor receptor superfamily, member 10a. NM_003844. Gene Info. TNFRSF10B. Tumor necrosis factor receptor ... Transcribed locus, strongly similar to NP_665802.1 TNF receptor-associated factor 6 [Homo sapiens]. BQ948628. Gene Info. ... Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain. NM_003840. Gene Info. ...
https://cgap.nci.nih.gov/Genes/GoGeneQuery?PAGE=1&ORG=Hs&GOID=1901222
*  Frontiers | DNA Damage Response and Autophagy: A Meaningful Partnership | Genetics
TNF receptor-associated factor interacting protein 2; TSC2, Tuberous Sclerosis Complex 2; ULK1, unc-51-like autophagy- ... 2013). Regulation of autophagy by stress-responsive transcription factors. Semin. Cancer Biol. 23, 310-322. doi: 10.1016/j. ... TAK1 also engages the JNK pathway which activates various transcription factors, including AP1. NF-κB and AP1 transcribe genes ... 2002). DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 296, 530- ...
https://www.frontiersin.org/articles/10.3389/fgene.2016.00204/full
*  GADD45 protein Summary Report | CureHunter
TNF Receptor-Associated Factor 2 (TRAF2) 7. Tumor Necrosis Factor Receptor-Associated Peptides and Proteins ... Eukaryotic translation initiation factor 5A(eIF-5A), Protein DJ-1, Annexin V, Transcription elongation factor B polypeptide 2 ( ... 2. Hepatocellular Carcinoma (Hepatoma) 12/01/2003 - "Transient transfection of GADD45 gamma cDNA with intact open reading frame ... 04/01/2008 - "A total of 43 differentially expressed proteins were visualized by 2-DE and silver stain., 29 proteins of which ...
http://www.curehunter.com/public/keywordSummaryC086050-GADD45-protein.do
*  Common variants at CD40 and other loci confer risk of rheumatoid arthritis | Nature Genetics
Cooperation between TNF receptor-associated factors 1 and 2 in CD40 signaling. . J. Immunol. 176, 5388-5400 (2006). ... a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and ... Beyond TNF: TNF superfamily cytokines as targets for the treatment of rheumatic diseases *Michael Croft ... A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis. . PLoS Med. 4, e278 (2007). ...
https://www.nature.com/articles/ng.233?error=cookies_not_supported&code=112207f8-2e26-4c1f-9d62-7e3336f83e35
*  TRAF-2 Antibody (33A1293) [DyLight 680] (NB100-56715FR): Novus Biologicals
Mouse Monoclonal Anti-TRAF-2 Antibody (33A1293) [DyLight 680]. Validated: WB, IHC, IHC-P. Tested Reactivity: Human. 100% ... TNF receptor-associated factor 2. *TRAF2. *TRAF-2. *TRAP3. *TRAP3TRAP. *tumor necrosis factor type 2 receptor associated ... TRAF-2 Antibody (33A1293) [DyLight 680] Summary. Immunogen. Anti-TRAF2 monoclonal antibody was raised against a fusion protein ... FAQs for TRAF-2 Antibody (NB100-56715FR) (0). There are no specific FAQs related to this product. Read our general customer & ...
https://www.novusbio.com/products/traf-2-antibody-33a1293_nb100-56715fr
*  TRAF-2 Antibody (4C11) (H00007186-M04A): Novus Biologicals
Mouse Monoclonal Anti-TRAF-2 Antibody (4C11). Validated: WB, ELISA. Tested Reactivity: Human. 100% Guaranteed. ... TRAF2 - TNF receptor-associated factor 2 (4C11). Isotype. IgG2a Kappa. Clonality. Monoclonal ... responses mediated by tumor necrosis factor is initiated by its interaction with the TNFR1 and TNFR2 cell surface receptors. ... TRAF-2 Antibody (4C11) Summary. Immunogen. TRAF2 (AAH43492, 1 a.a. - 501 a.a.) full-length recombinant protein with GST tag. MW ...
https://www.novusbio.com/products/traf-2-antibody-4c11_h00007186-m04a
*  Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of Nuclear Factor-κB and c-jun N-terminal kinase (JNK/SAPK)...
TNF,. tumor necrosis factor;. TRAF,. TNF receptor-associated factor;. MEKK1,. mitogen-activated protein kinase/extracellular ... TNF-induced activation of both NF-κB and JNK requires TNF receptor-associated factor 2 (TRAF2) (12-16), a member of the TRAF ... TNF-induced activation of the transcription factor NF-κB and the c-jun N-terminal kinase (JNK/SAPK) requires TNF receptor- ... TNF receptor-associated factor 6. Cytokine-induced activation of otherwise latent transcription factors is one of the ...
https://www.pnas.org/content/94/18/9792?ijkey=49d6ce3327ca5469a8b63ddf3d1359d733702e4e&keytype2=tf_ipsecsha
*  Frontiers | OX40 Agonists and Combination Immunotherapy: Putting the Pedal to the Metal | Oncology
OX40-mediated memory T cell generation is TNF receptor-associated factor 2 dependent. J Immunol (2003) 171(11):5997-6005. doi: ... Targeting tumor-necrosis factor receptor pathways for tumor immunotherapy. J Immunother Cancer (2014) 2:7. doi:10.1186/2051- ... Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in ... which can be provided through ligation of tumor necrosis factor receptor family members, including OX40 (CD134) and 4-1BB ( ...
https://www.frontiersin.org/articles/10.3389/fonc.2015.00034/full
*  SMART: MATH domain annotation
STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 (TRAF2). 1ca9. STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A ... STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 (TRAF2) IN COMPLEX WITH A HUMAN OX40 PEPTIDE. ... STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A 17-RESIDUE CD40 PEPTIDE. ... STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A 5-RESIDUE CD40 PEPTIDE. ...
http://smart.embl.de/smart/do_annotation.pl?DOMAIN=MATH&START=24&END=130&E_VALUE=1.77e-5&TYPE=SMART&BLAST=WTISNFSFCMGGIQRRITSPVFSSEENKEVAWCLRVYPKGADKESKDYLSVYLVLLSHLQIPVWAKFKFWIINSQGEKYQKIKSPTVECFLTNEQNGFKKFLPRDLL
*  Rel/NF-kappaB target genes
TNF receptor-associated factor 1. 601711 human. NM_005658 NM_005658 NM_009421 ... TNF receptor-associated factor 2. 601895 human. NM_021138 NM_021138 NM_009422 ... TNF. tumor necrosis factor (TNF superfamily, member 2) TNF alpha. 191160 human. NM_000594 NM_000594 NM_013693 -579/-586,-202/- ... tumor necrosis factor receptor superfamily, member 6 (cCD95 Fas). 134637 human. NM_000043 NM_000043 NM_007987 -295/-286. ...
https://bioinfo.lifl.fr/NF-KB/
*  Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats | BMC Nephrology | Full Text
... tumor necrosis factors alpha (TNF-α), TNF Receptor-Associated Factor 2 (TRAF2), and interleukin-1 alpha (IL-1-α). The cisplatin ... and TNF-α (300%) genes compared to control group. Additionally, histopathological examination showed that cisplatin-induced ... inhibiting the interconnected ROS/JNK/TNF/P38 MAPK signaling pathways, and repairing the histopathological changes against ... Rats of group 1 control group intraperitoneal (i.p.) received 2.5 ml/kg, group 2 CP group received single dose 5 mg/kg ...
https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-017-0601-y
*  MODULE 486
TNF receptor-associated factor 2. 7226. 7226. TRPM2. transient receptor potential cation c.... ... TFT: transcription factor targets C4: computational gene sets CGN: cancer gene neighborhoods CM: cancer modules C5: GO gene ...
http://software.broadinstitute.org/gsea/msigdb/cards/MODULE_486.html
*  Antitumor activity of irradiated riboflavin on human renal carcinoma cell line 786-O | SpringerLink
... and tumor necrosis factor receptor superfamily, member 1a (TNFR1)/TNFRSF1A-associated via death domain (TRADD)/TNF receptor- ... IR treatment was characterized by downregulation of Fas ligand (TNF superfamily, member 6)/Fas (TNF receptor superfamily member ... Apoptosis-inducing agents cause rapid shedding of tumor necrosis factor receptor 1 (TNFR1). A nonpharmacological explanation ... Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1. ...
https://link.springer.com/article/10.1007/s13277-014-2675-5
*  Khan, W.<...
TNF Receptor-Associated Factor 2 Inhibitor of Apoptosis Proteins Stage-specific Signaling in Peripheral B Cell Selection. Khan ...
https://miami.pure.elsevier.com/en/persons/wasif-khan
*  Apoptosis in cancer : Carcinogenesis - oi
TNF receptor-associated factor. Journal Article. 10687 words. Illustrated. Subjects: Clinical Cytogenetics and Molecular ... Keywords: IGF, insulin-like growth factor; NF-κB, nuclear factor κB; PTP, permeability transition pore; TNF-α, tumor necrosis ...
http://oxfordindex.oup.com/view/10.1093/carcin/21.3.485
*  ZFIN Publication: Santoro et al., 2007
Receptors, Tumor Necrosis Factor, Type I/metabolism. *Signal Transduction. *TNF Receptor-Associated Factor 2/metabolism ... Using genetic and molecular approaches, we show that Birc2 positively regulates the formation of the TNF receptor complex I in ... Our findings identify Birc2 and TNF signaling components as critical regulators of vascular integrity and endothelial cell ...
https://zfin.org/ZDB-PUB-071016-8