Thrombomodulin is also expressed on human mesothelial cell, monocyte and a dendritic cell subset. In humans, thrombomodulin is ... Thrombomodulin (TM), CD141 or BDCA-3 is an integral membrane protein expressed on the surface of endothelial cells and serves ... Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming ... IPR001491 Thrombomodulin Accessed January 19, 2012. Verhagen HJ, Heijnen-Snyder GJ, Pronk A, Vroom TM, van Vroonhoven TJ, ...
... type I membrane glycoprotein also known as thrombomodulin, TM, THRM, THBD, and fetomodulin. CD141 is an important cofactor in ... Brilliant Violet 421™ anti-human CD141 (Thrombomodulin). M80. FC. Brilliant Violet 785™ anti-human CD141 (Thrombomodulin). M80 ... Thrombomodulin, TM, THRM, THBD, Fetomodulin, BDCA-3 Isotype Mouse IgG1, κ Barcode Sequence GGATAACCGCGCTTT Ave. Rating Submit a ... CD141 is a 75 kD, single chain, type I membrane glycoprotein also known as thrombomodulin, TM, THRM, THBD, and fetomodulin. ...
Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke. *Mark ... Here we pursue an a priori hypothesis that genetic variation in the endothelial-based receptors of the thrombomodulin-protein C ... Here we pursue an a priori hypothesis that genetic variation in the endothelial-based receptors of the thrombomodulin-protein C ... Here we pursue an a priori hypothesis that genetic variation in the endothelial-based receptors of the thrombomodulin-protein C ...
... experiments on the thrombin-thrombomodulin (TM) complex. Thrombin promotes procoagulative fibrinogen cleavage when fibrinogen ... experiments on the thrombin-thrombomodulin (TM) complex. Thrombin promotes procoagulative fibrinogen cleavage when fibrinogen ...
... recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating ... Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin ... Bound to thrombin, Thrombomodulin alfa inhibits its procoagulant activity and promotes activation of protein C. Thrombomodulin ... Thrombomodulin alfa is a soluble form of recombinant human thrombomodulin comprising all extracellular domains of ...
Thrombomodulin-related bleeding disorder. Synonyms: THBD-related bleeding disorder , THBD-related coagulopathy , Thrombomodulin ... Thrombomodulin-related bleeding disorder?. Our RARE Concierge Services Guides are available to assist you by providing ... Thrombomodulin-related bleeding disorder. Get in touch with RARE Concierge.. Contact RARE Concierge ... Abnormal laboratory findings include markedly elevated plasma thrombomodulin reduced prothrombin consumption and decreased ...
How Thrombomodulin Enables W215A/E217A Thrombin to Cleave Protein C but Not Fibrinogen. Title: How Thrombomodulin Enables W215A ... Thrombomodulin (THBD) gene variants and thrombotic risk in a population-based cohort study. Title: Thrombomodulin (THBD) gene ... CLECT_thrombomodulin_like; C-type lectin-like domain (CTLD) of the type found in human thrombomodulin(TM), Endosialin, C14orf27 ... Plasma Thrombomodulin Levels and Ischemic Stroke: A Population-Based Prognostic Cohort Study. Title: Plasma Thrombomodulin ...
baboon - complement-regulatory proteins - costimulation blockade - heart - pig - thrombomodulin - thrombotic microangiopathy - ... expressed human thrombomodulin (TBM). Immunosuppression included anti-thymocyte globulin with anti-CD154mAb (Regimen 1: n=2) or ... expressed human thrombomodulin (TBM). Immunosuppression included anti-thymocyte globulin with anti-CD154mAb (Regimen 1: n=2) or ... exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade ...
... thrombomodulin; t-PA = tissue type plasminogen activator; u-PA = urokinase plasminogen activator; XL= crosslinked. ...
5) Increases in soluble thrombomodulin and EPCR likely leave less surface bound forms, inhibiting the ability of endothelial ... 2) Endothelial surface bound thrombomodulin and EPCR lead to activation of protein C; PAR-1 activation strengthens endothelial ...
Dendritic cells (DCs) bridge the connection between innate and adaptive immunity. DCs present antigens to T cells and stimulate potent cytotoxic T-cell responses. Metabolic reprogramming is critical for DC development and activation; however, metabolic adaptations and regulation in DC subsets remain …
Thrombomodulin and antibeta2-glycoprotein I in stroke in children Ewa Pilarska, Malgorzata Lemka, [...] Alicja Bakowska - Show ... Thrombomodulin and antibeta2-glycoprotein I in stroke in children Ewa Pilarska, Malgorzata Lemka, Alicja Bakowska ...
Here we pursue an a priori hypothesis that genetic variation in the endothelial-based receptors of the thrombomodulin-protein C ... Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke ... Here we pursue an a priori hypothesis that genetic variation in the endothelial-based receptors of the thrombomodulin-protein C ... Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke. PloS one ...
Mouse TM (Thrombomodulin) CLIA Kit , G-EC-01664 MSRP: Was: Now: $266.00 - $4,134.00 ...
Idiopathic pulmonary fibrosis Acute exacerbation Recombinant human thrombomodulin α Hypercoagulability Received 23 Jun 2015 / ... Recombinant human thrombomodulin α has the possibility of improving prognosis in acute exacerbation of idiopathic pulmonary ... We studied the efficacy of recombinant human thrombomodulin (rhTM) α for acute exacerbation of idiopathic pulmonary fibrosis. ... Efficacy of recombinant human thrombomodulin α in acute exacerbation of idiopathic pulmonary fibrosis ...
Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 ... Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 ...
Downregulation of Thrombomodulin-Thrombin-Activated Protein C pathway as a mechanism for SARS-CoV-2 induced endotheliopathy and ... Agarwal S, Jacobi P, Sartain S. Downregulation of Thrombomodulin-Thrombin-Activated Protein C pathway as a mechanism for SARS- ... Thrombomodulin (TM) is an endothelial glycoprotein that plays a crucial role as a natural anticoagulant, binding thrombin to ... abstracts.isth.org/abstract/downregulation-of-thrombomodulin-thrombin-activated-protein-c-pathway-as-a-mechanism-for-sars-cov-2 ...
Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression. ... Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression. / ... Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression. In ... Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression. ...
Novel Sepsis Phenotypes, Effect of Thrombomodulin on Mortality in Sepsis-Associated Coagulopathy, Effect of Laparoscopic vs ...
Matsuo, S., Ikeda, T., Ikeda, K. et al. Comparison of the effects of recombinant human soluble thrombomodulin for systemic ... Recombinant human soluble thrombomodulin (rhs-TM) has a potent anticoagulant effect on septic disseminated intravascular ... Comparison of the effects of recombinant human soluble thrombomodulin for systemic inflammatory response syndrome-associated ... Comparison of the effects of recombinant human soluble thrombomodulin for systemic inflammatory response syndrome-associated ...
Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy The SCARLET ... 2019). Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy The ... 2019). Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy The ...
Known substrates of RHBDL2 include thrombomodulin and epidermal growth factor; profiling of the substrate repertoire of RHBDL2 ... December 2011). "Functions of rhomboid family protease RHBDL2 and thrombomodulin in wound healing". The Journal of ...
The NLR was negatively predicted by RAGE in addition to IL4 and positively predicted by thrombomodulin and procalcitonin. ...
Thrombin, in turn, converts fibrinogen to fibrin; activates soluble FV, FVIII, FXI, and FXIII; and binds to thrombomodulin to ...
Exploring traditional and nontraditional roles for thrombomodulin. Blood. (2018) 132:148-58. doi: 10.1182/blood-2017-12-768994 ... The binding of thrombin to endothelial-bound thrombomodulin, in addition, activates the anticoagulant pathway of protein C (17 ...
Thrombomodulin and protein C are members of an endogenous anticoagulant system. Thrombin complexed with thrombomodulin loses ...
Strong association between plasma thrombomodulin and pathergy test in Behcet disease. Ann Rheum Dis. 2008 Jun. 67(6):892-3. [ ... Vascular involvement in Behçets disease: relation with thrombophilic factors, coagulation activation, and thrombomodulin. Am J ...
Malignant cells are positive for CK7, CK20, p63, thrombomodulin, and GATA3. Many tumors are also positive for uroplakin III. ... By immunohistochemistry, benign Brenner tumors are positive for CK7, p63, GATA3, uroplakin III, and thrombomodulin. CK20 is ...