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*  Thienamycins - Biology-Online Dictionary
thienamycins beta-lactam antibiotics that differ from penicillins in having the thiazolidine sulfur atom replaced by carbon, ... Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors. ... Retrieved from "https://www.biology-online.org/dictionary/index.php?title=Thienamycins&oldid=33867" ...
https://www.biology-online.org/dictionary/Thienamycins
*  Thienamycin - Wikipedia
... thienamycin remains antimicrobially active. Thienamycin displayed high activity against bacteria that were resistant to other β ... allowing for the structural elucidation of thienamycin in 1979 (Figure 1). Thienamycin was the first among the naturally ... Thienamycin also known as Thienpenem is one of the most potent naturally produced antibiotics known thus far, was discovered in ... Thienamycin has excellent activity against both Gram-positive and Gram-negative bacteria and is resistant to bacterial β- ...
https://en.wikipedia.org/wiki/Thienamycin
*  Meropenem Versus Meropenem Plus Glycopeptide in Patients With Febrile Neutropenia After Allogenic Blood Stem Cell...
Patients submitted to allogenic transplant with neutropenia (neutrophils account , 500/mm3 or neutrophils account , 1000/mm3 with prevision to decrease until 500/mm3 at the next 24-48 h); Signs and symptoms to infection; Fever (Temperature, 38,3 ºC registered one time, or 38 ºC en two times separated 60 minutes in a period of 12 h ...
https://clinicaltrials.gov/show/NCT00462878
*  Imipenem - DrugBank
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic ... Thienamycins. Alternative Parents. Alpha amino acids and derivatives / Pyrroline carboxylic acids / Azepines / Vinylogous ... Thienamycin / Alpha-amino acid or derivatives / Pyrroline carboxylic acid / Pyrroline carboxylic acid or derivatives / Azepine ... Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic ...
https://www.drugbank.ca/drugs/DB01598
*  Ertapenem - DrugBank
Thienamycins. Alternative Parents. Acylaminobenzoic acid and derivatives / Proline and derivatives / Alpha amino acid amides / ... Thienamycin / Acylaminobenzoic acid or derivatives / Proline or derivatives / Alpha-amino acid amide / Alpha-amino acid or ... This compound belongs to the class of organic compounds known as thienamycins. These are beta-lactam antibiotics that differ ...
https://www.drugbank.ca/drugs/DB00303
*  Patent US4425337 - Adjuvants for rectal delivery of drug - Google Patents
... thienamycin and derivatives thereof such as N-formimidoyl thienamycin and gentamicin), antiarrythmics, polypeptides, ... N-formimidoyl thienamycin. (6R-cis)-3-[[Aminocarbonyloxy]methyl]-7-methyoxy-8-oxo-7-[(2-thienylacetyl))amino]-5-thia-1- ...
http://www.google.com/patents/US4425337?dq=6650327
*  Pleural Empyema disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
Thienamycins. Phase 3. 13. Salmon Calcitonin. Approved, Investigational. 47931-85-1. 16129616 ...
https://www.malacards.org/card/pleural_empyema
*  Simple Accordion with CSS & jQuery by Soh Tanaka
Thienamycin: Kametani, T.; Nagahara, T.; Ihara, M. J. Chem. Soc., Perkin Trans. I 1981, 3048; Ihara, M.; Konno, F.; Fukumoto, K ... Thienamycin: Kametani, T.; Huang, S.-P.; Ihara, M. Heterocycles 1979, 12, 1183, 1189; ...
http://www.orgsyn.org/demo.aspx?prep=v77p0236
*  Etymologia: Carbapenem - Volume 25, Number 7-July 2019 - Emerging Infectious Diseases journal - CDC
Antibacterial activities of a new stabilized thienamycin, N-formimidoyl thienamycin, in comparison with other antibiotics. ... Kahan JS, Kahan FM, Goegelman R, Currie SA, Jackson M, Stapley EO, et al. Thienamycin, a new beta-lactam antibiotic. I. ... The first carbapenem, thienamycin (theion ["sulfur"] + enamine [an unsaturated compound that forms the backbone of the molecule ... The first carbapenem approved for use in the United States was imipenem, the stable N-formimidoyl derivative of thienamycin, in ...
https://wwwnc.cdc.gov/eid/article/25/7/et-2507_article
*  Imipénem and breastfeeding. Are they compatible?
N-formimidoyl thienamycin. Group. Imipénem belongs to this group or family:. *ATC J01DF: Beta-Lactam Monobactams antibacterials ...
http://e-lactancia.org/breastfeeding/imipenem/writing/
*  Patent US5147867 - Phosphorus containing enzyme inhibitors - Google Patents
Combination of thienamycin-type antibiotics with dipeptidase inhibitors. US4715994 *. Nov 5, 1986. Dec 29, 1987. Merck & Co., ... Renal dehydropeptidase (E.C. 3.4.13.11) is a mammalian enzyme which metabolizes carbapenem antibiotics such as thienamycin and ...
http://www.google.com/patents/US5147867?dq=7800613
*  PRIMAXIN IV 250 Dosage & Rx Info | Uses, Side Effects - MPR
Carbapenem (thienamycin) + dehydropeptidase I inhibitor.. Interactions:. Concomitant ganciclovir (increased seizure risk), ...
http://www.empr.com/primaxin-iv-250/drug/1795/
*  PRIMAXIN IM 500 (Cilastatin sodium,Imipenem) dosage, indication, interactions, side effects | EMPR - ONA
Carbapenem (thienamycin) + dehydropeptidase I inhibitor.. Adverse Reactions:. Local reactions, GI upset, confusion, myoclonia, ...
https://www.oncologynurseadvisor.com/primaxin-im-500/drug/1797/
*  US Patent Class 540-- ORGANIC COMPOUNDS -- PART OF THE CLASS 532-570 SERIES
Thienamycin per se or salt thereof. 352. DF .~.~.~.~ Five-membered hetero ring consisting of one nitrogen, one sulfur and three ...
http://www.patentec.com/data/class/540.html
*  The Complete Book On Biotechnology Based Bulk Drugs by Npcs Board Of Consultants & Engineers, ISBN: 9788190439879 | NPCS
Thienamycin Discovery Chemistry Pharmacological Activity Chemical Synthesis Biosynthesis and Regulation of Thienamycin ... The cessation of thienamycin synthesis and carbon catabolite repression of synthesis. The cessation of thienamycin synthesis ... THIENAMYCIN Discovery Theinamycin was discovered by Kahan as a result of a screening procedure in which soil microorganisms ... Thienamycin and cephamycin C are b lactam antibiotics produced by S. cattleya. CO2+ was found to have no effect on the growth ...
https://www.niir.org/books/book/complete-book-on-biotechnology-based-bulk-drugs/isbn-9788190439879/zb,,122,a,0,0,a/index.html
*  Extended infusion versus intermittent infusion of imipenem in the treatment of ventilator-associated pneumonia
Antibacterial activity of imipenem: the first thienamycin antibiotic. Rev Infect Dis. 1985;7(Supplement 3):S389-S410. [PubMed] ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC5593413/
*  JCI - Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury
Kahan FM, Kropp H, Sundelof JG, Birnbaum J. Thienamycin: development of imipenen-cilastatin. J Antimicrob Chemother. 1983;12 ...
https://www.jci.org/articles/view/96640
*  Metronidazole Hydrochloride Monograph for Professionals - Drugs.com
Susceptibilities of anaerobic bacteria to N-formimidoyl thienamycin (MK0787) and to other antibiotics. Antimicrob Agents ...
https://www.drugs.com/monograph/metronidazole-hydrochloride.html
*  CELL-FREE PREPARATION OF CARBAPENEMS - GreenLight Biosciences, Inc.
... alternatives to thienamycin which maintain thienamycin's excellent antibacterial activity but are unfettered with thienamycin's ... In the S. cattleya pathway to thienamycin, the attachment of pantetheine to the carbapenem nucleus at the C-2 position is ... Production of thienamycin through traditional fermentation from Streptomyces cattleya also faced significant hurdles, such as ... Thienamycin was eventually considered ill-suited for clinical treatment due to its chemical instability due in aqueous media ...
http://www.freepatentsonline.com/y2017/0096692.html
*  Imipenem - Wikipedia
It was discovered via a lengthy trial-and-error search for a more stable version of the natural product thienamycin, which is ... Thienamycin has antibacterial activity, but is unstable in aqueous solution, so impractical to administer to patients. Imipenem ... Kahan, FM; Kropp, H; Sundelof, JG; Birnbaum, J (Dec 1983). "Thienamycin: development of imipenen-cilastatin". The Journal of ... Kesado, Tadataka; Hashizume, Terutaka; Asahi, Yoshinari (1980). "Antibacterial activities of a new stabilized thienamycin, N- ...
https://en.wikipedia.org/wiki/Imipenem