Loading...
*  Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological...
It is not known to what extent, if any, the decrease in other thiamine derivatives such as thiamine triphosphate (ThTP, [2]) ... Effect of thiamine and benfotiamine on the total thiamine content in thiamine-depleted Neuro 2a cells. The cells were grown for ... As the brain is particularly sensitive to thiamine deficiency, we wanted to test whether intracellular thiamine and thiamine ... Thiamine triphosphate and thiamine triphosphatase activities: from bacteria to mammals. Cell Mol Life Sci. 2003, 60: 1477-1488 ...
https://bmcpharma.biomedcentral.com/articles/10.1186/1471-2210-8-10
*  The ABCs of Vitamins: Vitamin B1 (Thiamine) | Breaking Muscle
... also known as thiamine, plays a large role in maintaining healthy skin, hair, eyes, and liver. It can also cause some strange ... Vitamin B1 is found in both plants and animal products. Your body uses it to form adenosine triphosphate or ATP, which every ... High doses of thiamine intake do not appear to cause any risk of toxicity. In fact thiamine is often supplemented in high doses ... 3. 'Thiamine (Vitamin B1).' Mediline Plus. September 2012. 4. 'Vitamin B1 (thiamine).' University of Maryland Medical Center. ...
https://breakingmuscle.com/healthy-eating/the-abcs-of-vitamins-vitamin-b1-thiamine
*  Thiamine as an adjunctive therapy in cardiac surgery: a randomized, double-blind, placebo-controlled, phase II trial | Critical...
12]. ATP adenosine triphosphate, CoA coenzyme A, TCA tricarboxylic acid. We hypothesized that thiamine administration prior to ... with one patient in the thiamine group and zero patients in the placebo group having thiamine deficiency. Thiamine levels were ... Thiamine levels were similar between the thiamine and placebo group prior to the surgery (14 nmol/L [11, 18] vs. 14 nmol/L [12 ... Alternatively, thiamine could be beneficial for the group that develops thiamine deficiency during surgery but there is no way ...
https://ccforum.biomedcentral.com/articles/10.1186/s13054-016-1245-1
*  Vitamin B1/ Thiamine Shortage and Perk - samley.co
Thiamine is had to make adenosine triphosphate (ATP), the body's primary energy-carrying particle, within the mitochondria of ... Vitamin B1/ Thiamine Shortage. Vitamin B1, which is additionally described as thiamine, is a coenzyme made use of by the body ... Finest Resources of Vitamin B1 (Thiamine). Vitamin B1Thiamine Shortage and Perk. The wealthiest food resources of thiamine ... It is thought that in between 30% -80% of problem drinkers have thiamine shortage. High dosages of thiamine could additionally ...
http://www.samley.co/vitamin-b1-thiamine-shortage-and-perk/
*  Thiamine triphosphate - Wikipedia
Yusa T. (1962). "Studies on thiamine triphosphate II. Thiamine triphosphate as phosphate donor". Plant cell. 3: 95-103. Rindi G ... by a specific thiamine-triphosphatase. It can also be converted into ThDP by thiamine-diphosphate kinase. Thiamine triphosphate ... "Thiamine triphosphate and thiamine triphosphatase activities: from bacteria to mammals". Cell. Mol. Life Sci. 60 (7): 1477-88. ... Thiamine triphosphate (ThTP) is a biomolecule found in most organisms including bacteria, fungi, plants and animals. Chemically ...
https://en.wikipedia.org/wiki/Thiamine_triphosphate
*  Adenosine thiamine triphosphate - Wikipedia
Adenosine thiamine triphosphate (AThTP), or thiaminylated adenosine triphosphate, is a natural thiamine adenine nucleotide. It ... Jordan F (2007). "Adenosine triphosphate and thiamine cross paths". Nat. Chem. Biol. 3 (4): 202-3. doi:10.1038/nchembio0407-202 ... In E. coli AThTP is synthesized from thiamine diphosphate (ThDP) according to the following reaction catalyzed by thiamine ... "Adenosine thiamine triphosphate (AThTP) inhibits poly(ADP-ribose) polymerase-1(PARP-1) activity". J Nutr Sci Vitaminol (Tokyo ...
https://en.wikipedia.org/wiki/Adenosine_thiamine_triphosphate
*  Thiamine triphosphate and adenosine thiamine triphosphate: metabolism and physiological significance - Bettendorff Lucien
Reference : Thiamine triphosphate and adenosine thiamine triphosphate: metabolism and physiologic.... Document type :. ... Thiamine triphosphate and adenosine thiamine triphosphate: metabolism and physiological significance. Language :. English. ...
https://orbi.uliege.be/handle/2268/126912
*  Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress |...
... thiamine triphosphate (ThTP) and the newly discovered adenosine thiamine triphosphate (AThTP). While, ThTP accumulation ... of total thiamine. Here, we address the question whether AThTP accumulation in E. coli is triggered by the absence of a carbon ... most of it in the form of the cofactor thiamine diphosphate (ThDP). Free ThDP is the precursor for two triphosphorylated ... thiamine triphosphate (ThTP) and the newly discovered adenosine thiamine triphosphate (AThTP). While, ThTP accumulation ...
https://0-bmcmicrobiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2180-10-148
*  Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino)pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a...
The triphosphate ester of thiamine. In Leigh's disease, this compound is present in decreased amounts in the brain due to a ... Thiamine Triphosphate. 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8- ...
https://www.bioportfolio.com/resources/pmarticle/2346098/Discovery-of-R-5-5-1-methyl-1H-pyrazol-4-yl-4.html
*  Pharmacologic Properties of Polyethylene Glycol-Modified Bacillus thiaminolyticus Thiaminase I Enzyme | Journal of Pharmacology...
Other intracellular forms of phosphorylated thiamine include thiamine monophosphate, thiamine triphosphate. and adenosine ... Thiamine monophosphate and thiamine diphosphate were substituted for thiamine as substrates, and the relative activity of ... Next, we examined intracellular thiamine and thiamine diphosphate (thiamine pyrophosphate) in RS4 cells exposed to equal ... thiamine diphosphate) and thiamine monophosphate (Table 1). Both phosphorylated thiamine derivatives were substrates for both ...
http://jpet.aspetjournals.org/content/341/3/775.full
*  Human recombinant thiamine triphosphatase: purification, secondary structure and catalytic properties - Lakaye Bernard
en] Thiamine triphosphate (ThTP) is found in most living organisms and it may act as a phosphate donor for protein ... en] thiamine triphosphate ; Fourier-transform infrared spectroscopy ; zinc ions ; diethylpyrocarbonate ; Woodward's reagent K. ... We have recently cloned the cDNA coding for a highly specific mammalian 25 kDa thiamine triphosphatase (ThTPase; EC 3.6.1.28). ...
http://orbi.ulg.ac.be/handle/2268/4630
*  Nutrition 2 Flashcards by Jane Schumacher | Brainscape
... thiamin triphosphate (TTP) may be involved in sodium conductance at axonal membranes. Thiamine is a cofactor for several ... if not enough thiamin… CAC cycle stops. glucose in blood goes up… PDH would not work without thiamin. Slide 40 ... Thiamin-dependent enzymes:. -transketolase. -pyruvate dehydrogenase. -alpha ketoglutarate dehydrogenase. Coenzyme (as thiamin ... Wernicke's encephalopathy in alcoholism - thiamin deficiency - must administer IV thiamin PRIOR to glucose otherwise can result ...
https://www.brainscape.com/flashcards/nutrition-2-4993409/packs/7288446
*  Acta Chemica Scandinavica
Cocarboxylase Activity of Thiamine Triphosphate in Yeast Transketolase.. Kiessling, Karl-Heinz. Pages: 663-667. ... Some Aspects of the Nutrition of Lactobacillus fermenti 36 in the Tube Assay of Thiamine.. B nhidi, Z. G.. Pages: 517-527. ...
http://actachemscand.dk/volume.php?select1=2&vol=12
*  Browse our Adenylate Kinase 1 ELISA Kits
AK1 is not involved in thiamine triphosphate synthesis in vivo * one of the consequences of M-CK (show CKM ELISA Kits) and AK1 ...
http://www.antibodies-online.com/nucleotide-phosphorylation-pathway-31/adenylate-kinase-1-elisa-kit-8958/
*  Disorders of Organic Acid Metabolism | SpringerLink
J. R. Cooper and J. H. Pincus, Role of thiamine triphosphate in subacute necrotizing encephalomyelopathy, Agr. Food. Chem. 20: ... M. G. Brunette, E. Devlin, B. Hazel, and C. R. Scriver, Thiamine responsive lactic acidosis in a patient with deficient low K m ... to glutamate coupled with cleavage of adenosine triphosphate to ade-nosine diphosphate, a reaction in the γ-glutamyl cycle, ...
https://link.springer.com/chapter/10.1007/978-1-4684-2673-1_3
*  TCDB » SEARCH
Thiamine triphosphatase is a soluble cytosolic enzyme which converts thiamine triphosphate to thiamine diphosphate. This domain ... They have a unique active site located at the center of an eight-stranded antiparallel beta barrel tunnel (the triphosphate ... CYTH-like superfamily enzymes hydrolyze triphosphate-containing substrates and require metal cations as cofactors. ... tunnel). The name CYTH originated from the gene designation for bacterial class IV adenylyl cyclases (CyaB), and from thiamine ...
http://www.tcdb.org/search/result.php?tc=4.E.1
*  Thtpa - ddPCR Probe - Digital PCR | PrimePCR | Bio-Rad
This gene encodes a cytosolic enzyme that catalyzes the conversion of thiamine triphosphate to thiamine diphosphate. The ... The gene product is believed to play a role in regulation of thiamine triphosphate intracellular concentration and it may be a ...
http://www.bio-rad.com/en-us/prime-pcr-assays/assay/dmmucpe5116872-primepcr-ddpcr-expression-probe-assay-thtpa-mouse
*  thiamine-diphosphate kinase(EC 2.7.4.15) - Creative Enzymes
... protein bound thiamin diphosphate:ATP phosphoryltransferase. Reaction. ATP + thiamine diphosphate = ADP + thiamine triphosphate ... thiamin diphosphate kinase; thiamin diphosphate phosphotransferase; thiamin pyrophosphate kinase; thiamine diphosphate kinase; ...
https://www.creative-enzymes.com/product/Thiaminediphosphate-Kinase_13365.html
*  Rhea - Annotated reactions database
... adenosine thiamine triphosphate + phosphate RHEA:35244 ADP + H(+) + thiamine diphosphate =, adenosine thiamine triphosphate + ... ADP + H(+) + thiamine diphosphate ,=, adenosine thiamine triphosphate + phosphate Last modified: 2014-11-22. Chemically ...
https://www.rhea-db.org/reaction?id=35246
*  ORBi: Browsing ORBi
Background: Thiamine triphosphate (ThTP) is present in most organisms and might be involved in intracellular signaling. In ... Background: Thiamine triphosphate (ThTP) is present in most organisms and might be involved in intracellular signaling. In ... Results: Triphosphate binding requires three conserved arginines while the catalytic mechanism relies on an unusual lysine- ... Conclusion: The specificity for ThTP is linked to a stacking interaction between the thiazole heterocycle of thiamine and a ...
http://orbi.ulg.ac.be/browse?type=author&value=Charlier,%20Paulette%20p000809
*  Biomolecules Test and Flashcards
Thiamine triphosphate (ThTP) is a biomolecule found in most organisms including bacteria, fungi, plants and animals. ... Thiamine triphosphate (ThTP) is a biomolecule found in most organisms including bacteria, fungi, plants and animals. ... Thiamine triphosphate, Beta-Hydroxy beta-methylbutyric acid, Crotonyl-CoA, Beta-Hydroxybutyryl-CoA, ER oxidoreductin, ...
https://studylib.net/flashcards/set/biomolecules_2535
*  EC 3.6.1 and EC 3.6.2
Accepted name: thiamine-triphosphatase. Reaction: thiamine triphosphate + H2O = thiamine diphosphate + phosphate. For diagram ... Glossary: thiamine diphosphate. Systematic name: thiamine-triphosphate phosphohydrolase. Links to other databases: BRENDA, ... Reaction: triphosphate + H2O = diphosphate + phosphate. Other name(s): inorganic triphosphatase. Systematic name: triphosphate ... Reaction: a nucleoside triphosphate + H2O = a nucleoside diphosphate + phosphate. Other name(s): nucleoside triphosphate ...
http://www.sbcs.qmul.ac.uk/iubmb/enzyme/EC3/0601p.html
*  Thiamin - Poultry - Compendium - DSM
Of total body thiamin, about 80% is TPP, about 10% is thiamin triphosphate (TTP), and the remainder is thiamin monophosphate ( ... Ruminants can also absorb free thiamin from the rumen, but the rumen wall is not permeable for bound thiamin or for thiamin ... This leads to less thiamin, but it also results in thiamin analogs consisting of the pyrimidine ring of the original thiamin ... Maternal thiamin supplementation of the hen increased heart thiamin in broiler offspring. Thiamin requirements are obviously ...
https://www.dsm.com/markets/anh/en_US/Compendium/poultry/thiamin.html
*  Thiamin - Companion animals - Compendium - DSM
Of total body thiamin, about 80% is TPP, about 10% is thiamin triphosphate (TTP), and the remainder is thiamin monophosphate ( ... Thiamin deficiency may result from inadequate intake of thiamin, attributable to foods with low-thiamin content or processing ... Ruminants can also absorb free thiamin from the rumen, but the rumen wall is not permeable for bound thiamin or for thiamin ... This leads to less thiamin, but it also results in thiamin analogs consisting of the pyrimidine ring of the original thiamin ...
https://www.dsm.com/markets/anh/en_US/Compendium/companion_animals/thiamin.html