... with epithelial cell tumors (>70%) comprising the largest group of tumors. Germ cell tumors occur less frequently (20%), while ... encoded search term (Granulosa-Theca Cell Tumors) and Granulosa-Theca Cell Tumors What to Read Next on Medscape ... Granulosa-theca cell tumors, also known as granulosa cell tumors (GCTs), represent about 2% of all ovarian tumors. GCTs can be ... Granulosa-theca cell tumors, more commonly known as granulosa cell tumors (GCTs), belong to the sex cord-stromal category and ...

The theca are divided into two layers, the theca interna and the theca externa. Theca cells are a group of endocrine cells in ... Theca cells and granulosa cells together form the stroma of the ovary. Theca cells are responsible for synthesizing androgens, ... Theca cells (along with granulosa cells) form the corpus luteum during oocyte maturation. Theca cells are only correlated with ... may both granulosa cells and theca cells. Thecomas are benign proliferations of theca cells that may present with hormonal ...

Comparison of effects of different statins on growth and steroidogenesis of rat ovarian theca-interstitial cells. In: Biology ... Comparison of effects of different statins on growth and steroidogenesis of rat ovarian theca-interstitial cells. Biology of ... keywords = "Cyp17a1, Ovarian theca-interstitial cells, Proliferation, Statins, Steroidogenesis",. author = "Anna Sokalska and ... Comparison of effects of different statins on growth and steroidogenesis of rat ovarian theca-interstitial cells. / Sokalska, ...

Return to Article Details A Challenging Task-How to Successfully Separate Theca and Granulosa Cells: A Mandatory Step for ...

Changes in fibroblast growth factor 9 mRNA in granulosa and theca cells during ovarian follicular growth in dairy cattle. J ... Changes in fibroblast growth factor 9 mRNA in granulosa and theca cells during ovarian follicular growth in dairy cattle. ... Changes in fibroblast growth factor 9 mRNA in granulosa and theca cells during ovarian follicular growth in dairy cattle. ...

Nanos1A was strongly expressed in brain and also localized in all germ cell types in the polarized testis. In contrast, nanos1B ... In addition, Nanos1B protein was predominantly located in the nuclei of male germinal cells. In the ovary, both paralogs were ... detected in germinal and somatic cells. Our study opens new perspectives concerning the complex evolution of nanos1 paralogs ... Nanos are RNA-binding proteins playing crucial roles in germ cell development and maintenance. Based on phylogenetic and ...

Effect of antipsychotics on mitochondrial bioenergetics of rat ovarian theca cells Toxicology Letters. 272, 94-100 ... The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line Cancer ... The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line Cancer ... Thecal cell sensitivity to luteinizing hormone and insulin in polycystic ovarian syndrome REPRODUCTIVE BIOLOGY. 16(1), 53-60 ...

Estradiol - Primarily produced by theca and granulosa cells of the ovary; it is the predominant form of estrogen found in ...

Granulosa-theca cell tumor. 2. 0. Adenocarcinoma. 3. 0. Skin. Histiocytoma. 2. 0. ... Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines. Oral Oncology 52:58-65. ... the mean number of micronucleated cells/1,000 cells was 21 percent higher in e-cigarette users and 160 percent higher in ... Human bronchial epithelial cells (BEAS-2Bs).. Welz et al., 2016. E-liquids with the fruit flavors apple and cherry and one ...

El-Sheikh Ali H, Kitahara G, Nibe K, et al. Plasma anti-Müllerian hormone as a biomarker for bovine granulosa-theca cell tumors ... El-Sheikh Ali H, Kitahara G, Nibe K, et al. Plasma anti-Müllerian hormone as a biomarker for bovine granulosa-theca cell tumors ... Enlarged ovary due to granulosa theca cell tumor. J Am Vet Med Assoc. 2015;247(2):153-155. ... Enlarged ovary due to granulosa theca cell tumor. J Am Vet Med Assoc. 2015;247(2):153-155. ...

29 Björkholm E. Granulosa-cell and theca-cell tumor. The clinical picture and long term out-come for the Radiumhemmet series. ... 48 Cronje H S, Niemand I, Bam R H, Woodruff J D. Review of the granulosa-theca cell tumors from the Emil Novak Ovarian Tumor ... 3 Evans A T, Gaffey T A, Malkasian G D, Annegers J F. Clinicopathological review of 118 granulosa and 82 theca cell tumors. ... 57 Anikuwe C, Dawood M Y, Kramer E. Granulosa and theca cell tumors. Obstet Gynecol. 1978; 51 214-220 ...

granulosa cell-theca cell (M8621/1) 236.2*. malignant (M8621/3) 183.0. *. Leydig cell (M8650/1)*. benign (M8650/0)*. specified ... Leydig cell*. tumor (M8650/1)*. benign (M8650/0)*. specified site - see Neoplasm, by site, benign ...

Follicle growth is dependent on the proliferation of theca and granulosa cells [43]. ... Sperm cells do not contain any cytoplasmic defense enzymes that can serve as ROS scavengers. Therefore, a change in lipid ... The mode of action of estrogen-mimicking EDCs is two-fold; firstly, their action is on the proliferation of stromal cells and, ... K. Svechnikov, G. Izzo, L. Landreh, J. Weisser, O. Sder, Endocrine disruptors and leydig cell function, J. Biomed. Biotechnol. ...

Follicle cysts are lined with an inner layer of granulosa cells and an outer layer of theca interna cells. The cysts are thin- ... When ovarian neoplasms are encountered in girls of this age group, they fall into the germ cell, epithelial cell, and stromal/ ... The most common germ cell tumor of this age group (and also the most common benign tumor) is the benign cystic teratoma (see ... The vast majority of ovarian lesions of childhood are of the germ cell variety, but only about 8% of ovarian tumors of ...

The most common types among this rare class of ovarian tumors are granulosa-theca tumors and Sertoli-Leydig cell tumors. These ... Germ cell tumors. Ovarian germ cell tumors develop from the cells that produce the ova or eggs. Most germ cell tumors are ... The baculovirus-insect cell expression system-insect cells used in conjunction with the baculovirus expression vector system ( ... The most common germ cell malignancies are maturing teratomas, dysgerminomas, and endodermal sinus tumors. Germ cell ...

Cysts can arise from follicle epithelium, theca-lutein cells, corpus luteum, but some are without a known origin [12]. The ... but can also be theca-lutein, corpus luteum or simple cysts whose origin cannot be determined [3]. Fetal ovarian cysts have ...

VEGF was predominantly produced in tissues that acquire new capillary networks (theca layers, lutein cells, endometrial stroma ... giant trophoblast cells, adrenal cortex, and Leydig cells). Furthermore, in some cells upregulation of VEGF expression is ... Vascular endothelial growth factor (VEGF) is a secreted endothelial cell-specific mitogen. To evaluate whether VEGF may play a ... Using in situ hybridization, we show that VEGF is expressed in 10 different steroidogenic and/or steroid-responsive cell types ...

Firstly, insulin promotes androgen synthesis from theca cells, either directly or by enhancing the response of theca cells to ... Theca cells are the predominant site of androgen production in the ovaries, and insulin acts on theca cells mainly via its own ... It seems that the theca cells of women with PCOS are hyperresponsive to the androgen-stimulating action of insulin [10] and ... In particular, a study that analyzed cytochrome P450 17α-hydroxylase (CYP17A1) expression in PCOS theca cells found an ...

... phthalate targets ovarian theca cells and steroidogenesis in the adult female rat. Reprod. Toxicol. 2015, 51, 47-56. [Google ... Thecal cells respond to LH, whereas granulosa cells respond to FSH. In response to LH, thecal cells take in cholesterol from ... Testosterone also diffuses from the thecal cells to the granulosa cells, where it can be converted along with estrone into the ... The schematic shows that primordial germ cells form germ cell nests, which subsequently break down to form a finite pool of ...

Theca cell tumor Nature: Benign Status: ... ... Human Tumor Cell Line Total Protein * Human Tumor Tissue Total ... Western blotting is an important technique used in cell and molecular biology. By using a weste … ...

Some of the most common types of malignant ovarian stromal tumors include granulosa cell tumors, granulosa-theca tumors and ... Stromal cells are among the three most common cell types to be affected by ovarian cancer; however, stromal tumors represent ... Because stromal tumors develop in the ovarian cells that produce female hormones, the tumors often end up producing estrogen, ... Ovarian stromal tumors develop in the ovaries structural connective tissue cells that produce the female hormones estrogen and ...

This rare form of ovarian tumor develops in the connective tissue cells, called granulosa and theca cells, that hold the ... Germ cell malignancies. This rare type of ovarian cancer develops in the egg-producing cells of the ovaries. Germ cell ... Some approaches, called "adoptive cell therapy," use cells called killer T cells from the immune system in an individual ... usually by keeping the cancer cells from growing, dividing, and making more cells or by destroying the cancer cells. ...

10.08.2015 Spontaneous Recovery of Granulosa-Theca Cell Tumour in a Heifer. *29.06.2015 Susceptibility to antimicrobials of ... 04.12.2017 Penile and preputial squamous cell carcinoma in the horse *22.11.2017 CT diagnosis of fatigue fracture of Mt 3 in ... 16.04.2017 Comparison of two techniques to count cells in equine BALF *15.04.2017 Cytokine Concentrations in BAL Fluid from ... 01.01.2015 Skeletal metastases from a penile squamous cell carcinoma in a horse. *26.12.2014 Post operative ileus in horses - a ...

by the aromatization of androstenedione (produced in the theca folliculi cells) to estrone, followed by conversion of estrone. ... Granulosa cell. A granulosa cell or follicular cell is a somatic cell of the sex cord that is closely associated with the ... s and the Sertoli cell. Sertoli cell. A Sertoli cell is a nurse cell of the testes that is part of a seminiferous tubule.It ... mainly in the Leydig cell. Leydig cell. Leydig cells, also known as interstitial cells of Leydig, are found adjacent to the ...

Conditions that cause elevated estrogen levels, such as anovulatory states or granulosa- theca cell tumors, increase the ...

Increased lipid accumulation was noted in interstitial cells and theca cells of both E-17beta treated and 5.0mg MxC treated ...

BPA may directly impact the ovarian theca cells to secrete androgens and additionally can displace Testosterone from SHBG, ... She pointed out, "They impact the cells of a very early embryo during pregnancy leading to problems. Phthalates are used to ... Ovarian fibrosis, apoptosis and pyroptosis of granulosa cells are the main consequences of MPs-induced oxidative stress in ... which ultimately affects tissue and organismal homeostasis in numerous human cells. Plastics (long polymer chains) are widely ...

"We have shown that resveratrol and other antioxidants reduced growth of ovarian theca cells and reduced production of androgens ... the commonest endocrine disorder affecting women of reproductive age and is characterized by hyperplasia of ovarian theca cells ... in ovarian cell cultures for several years. " ...

... expressing theca cells. DNA is gray. (C) Higher magnification of cyp17a1-expressing theca cells. IB, stage IB oocyte. Scale ... Top-left panel shows cells color-coded by computationally determined cell subtype. Cells expressing the indicated gene are ... Theca cell subcluster analysis.. (A) Gene expression uniform manifold approximation and projection (UMAP) plots of select genes ...

It is characterized by hyperandrogenism, which results primarily from excess androgen production by ovarian theca cells (TCs). ... such as cuboidalisation and proliferation of the granulosa cells (GC) as well as an increase in oocyte size.Cell adhesion ... GLUT4 expression and translocation in immortalised mouse granulosa cells. Joharatnam Jalini , Skodras Angelos , Hardy Kate , ... The role of thyroid hormone transporters MCT8 and MCT10 in the EVT-like cell line HTR8-SVneo. Choudhury Juhela , Loubiere ...