CiNii Articles - 
		
	 		 Th2 cells
 		
 		
 		
 		
 		
 		
 		
 		
 		
 		
 		
 		
 		
 	  CiNii Articles - Th2 cells
Administration of Th2 cell inhibitor abolished the increase in TEWL, IL-6, and TNF-α levels, whereas Th17 cell inhibitor ... non-B cells) and potently produce characteristic cytokines of T cell subsets (Th1, Th2, Th17). … ... The impact of pathogenic Th2 cells on the allergic disease of upper airway [in Japanese] 飯沼 智久 , 岡本 美孝 ... Pathogenicity of memory Th2 cells is linked to stage of allergic rhinitis [in Japanese] Iinuma T. , Okamoto Y. , Morimoto Y. , ...
more infohttps://ci.nii.ac.jp/keyword/Th2+cells
Th2 cells: help for helminths. | JEM  Th2 cells: help for helminths. | JEM
Pay Per Article - You may access this article (from the computer you are currently using) for 2 days for US$30.00. Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired.. ...
more infohttp://jem.rupress.org/content/179/5/1405
th2 cells  th2 cells
... th2 cellsJames Helminthic therapy is the purposeful inoculation by ingesting intestinal worms in an effort to treat disease, ...
more infohttp://www.gnet.org/tag/th2-cells/
Thymic stromal lymphopoietin drives the development of IL-13+ Th2 cells | PNAS  Thymic stromal lymphopoietin drives the development of IL-13+ Th2 cells | PNAS
Culture in Th2 conditions and TSLP generates a population of Th2 cells that express IL-13, IL-5, and IL-9. Naive CD4+ T cells ... T helper 2 (Th2) cells are pivotal in the development of allergy. Allergen exposure primes IL-4+ Th2 cells in lymph node, but ... primed Th2 cells in lung are able to differentiate into CXCR5loPD1lo Th2 effector cells that are GATA3+ and produce IL-13, but ... T cells into a population of IL-13-SP Th2 cells. The development of these cells in culture does not involve an IL-4+ stage and ...
more infohttp://www.pnas.org/content/115/5/1033
Interleukin-12 Receptor β2 Chain and TH2 Cells | Science Signaling  Interleukin-12 Receptor β2 Chain and TH2 Cells | Science Signaling
T cells differentiated into TH2 cells in the presence of IL-4, or IL-4 and IL-12. IL-12 treatment of TH2 cells expressing ... When naïve CD4+ T cells are treated simultaneously with both IL-4 and IL-12, the IL-4 effects predominate and TH2 cells develop ... Thus, TH2 cells are resistant to TH1 conversion, and decreased expression of IL-12Rβ2 is not necessary for the establishment of ... However, it is not known what effect constitutive expression of the IL-12Rβ2 chain has on the development of TH2 cells. ...
more infohttp://stke.sciencemag.org/content/2000/23/tw2
Opinions on whether TH1 and TH2 cell types originate from TH0  Opinions on whether TH1 and TH2 cell types originate from TH0
... Thierry Sornasse tsornas at dbmdec5.ulb.ac.be Wed Mar 9 11:37:41 ... Thus, there could be some memory T cells that are already shifted to Th1 or to Th2. In conclusion, I could say that the ... Hi Immunonetters, The discrimination between Th1 and Th2 phenotypes was established from data about T cell clones derived from ... DC activate naive T cells but do not trigger the differentiation of Th1, while Mac do not activate naive T cells but trigger ...
more infohttp://www.bio.net/bionet/mm/immuno/1994-March/001141.html
KEGG PATHWAY: Th1 and Th2 cell differentiation - Homo sapiens (human)  KEGG PATHWAY: Th1 and Th2 cell differentiation - Homo sapiens (human)
Th1 and Th2 cell differentiation - Homo sapiens (human) [ Pathway menu , Organism menu , Pathway entry , Download KGML , Hide ... On the other hand, transcription factors like GATA-3 and STAT6 drive the generation of Th2 cells that produce IL-4, IL-5 and IL ... The balance between Th1/Th2 subsets determines the susceptibility to disease states, where the improper development of Th2 ... These cells stimulate strong cell-mediated immune responses, particularly against intracellular pathogens. ...
more infohttps://www.genome.jp/kegg-bin/show_pathway?map=hsa04658&show_description=show
T follicular helper cells differentiate from Th2 cells in response to helminth antigens | JEM  T follicular helper cells differentiate from Th2 cells in response to helminth antigens | JEM
TFH cells) PD-1− GFP+ CD4+ T cells (Th2 cells) and GFP− CD4+ T cells (Naive T cells) sorted from the same LNs. Real-time RT-PCR ... cells that have differentiated into TFH cells provide help to B cells, whereas "conventional" Th2 cells traffic to peripheral ... Data are from gated CD4+ T cells. Numbers are percentages of cells in each quadrant. (E) Th2 cells (CD4+/GFP+/PD-1−/CXCR5−) ... PD-1+ Th2 cells and germinal center B cells develop in response to helminth infections or immunization with Th2 response ...
more infohttp://jem.rupress.org/content/206/5/991
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.  - PubMed - NCBI  Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. - PubMed - NCBI
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.. Kaplan MH1, Schindler U, Smiley ST, Grusby ... In addition, Stat6-deficient T lymphocytes fail to differentiate into Th2 cells in response to either IL-4 or Il-13. These ... We have generated Stat6-deficient mice by gene targeting in embryonic stem cells to determine the role of this transcription ... Interleukin-4 (IL-4) stimulation of cells leads to the activation of multiple signaling pathways, one of which involves Stat6. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/8624821?dopt=Abstract
Hierarchical IL-5 Expression Defines a Subpopulation of Highly Differentiated Human Th2 Cells | The Journal of Immunology  Hierarchical IL-5 Expression Defines a Subpopulation of Highly Differentiated Human Th2 Cells | The Journal of Immunology
Th2 cells. IL-5+ Th2 cells expressed less CD27 and greater programmed cell death-1 than IL-5− Th2 cells, consistent with their ... cells were triple positive. In both allergen-specific Th2 cells and IL-4-sorted Th2 cell lines, 98-100% of IL-5+ Th2 cells had ... Th2 cells. First, IL-5+ Th2 cells were almost exclusively IL-4+IL-5+IL-13+ triple-positive cells within the larger Th2 ... Th2 cells are highly differentiated T cells. The delayed acquisition of the IL-5+ Th2 phenotype implies that IL-5+ Th2 cells ...
more infohttp://www.jimmunol.org/content/187/6/3111
T-cell-intrinsic Tif1α/Trim24 regulates IL-1R expression on TH2 cells and TH2 cell-mediated airway allergy | PNAS  T-cell-intrinsic Tif1α/Trim24 regulates IL-1R expression on TH2 cells and TH2 cell-mediated airway allergy | PNAS
T-cell-intrinsic Tif1α/Trim24 regulates IL-1R expression on TH2 cells and TH2 cell-mediated airway allergy ... 1997) The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89(4): ... T-cell-intrinsic Tif1α/Trim24 regulates IL-1R expression on TH2 cells and TH2 cell-mediated airway allergy. Jimena Perez-Lloret ... 2011) T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma ...
more infohttp://www.pnas.org/content/113/5/E568
JCI -
Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway...  JCI - Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway...
Even on transfer of twice as many Th1 as Th2 cells (5 × 106 Th1 cells + 2.5 × 106 Th2 cells, Th1 + Th2 [2:1]), Th1 cells did ... B cells or γδ T cells are required for the development of Th2 effector cells from naive precursor cells but that once Th2 cells ... Th2 (2.5 × 106 cells per mouse), or Th1 plus Th2 (2.5 × 106 Th1 + 2.5 × 106 Th2 cells per mouse) cells in OVA-treated SCID mice ... Th2 and Th0 cells, but not Th1 cells, increase airway hyperreactivity. SCID mice received Th1, Th2, or Th0 cells (2.5 × 106 ...
more infohttps://www.jci.org/articles/view/5155
Dominik Niesen: Quantitative stability of GATA3 and IL-4 expression levels in Th2 cells - DRFZ  Dominik Niesen: Quantitative stability of GATA3 and IL-4 expression levels in Th2 cells - DRFZ
Rebecca Cornelis: Stromal cell contact-induced PI3K signaling prevents caspase-3 induced cell death of memory plasma cells ... Startseite Aktuelles Seminare Dominik Niesen: Quantitative stability of GATA3 and IL-4 expression levels in Th2 cells ... Dominik Niesen: Quantitative stability of GATA3 and IL-4 expression levels in Th2 cells AG Löhning. ... Marina Babic-Cac: NK cell receptor NKG2D enforces pro-inflammatory features and pathogenicity of Th1 and Th17 cells ...
more infohttps://www.drfz.de/aktuelles/news/aktuelles/seminare/dominik-niesen-quantitative-stability-of-gata3-and-il-4-expression-levels-in-th2-cells/
Targeting Th2 Cells in Asthmatic Airways | Bentham Science  Targeting Th2 Cells in Asthmatic Airways | Bentham Science
Targeting Th2 Cells in Asthmatic Airways. Author(s): Gaetano Caramori , Kazuhiro Ito , Ian M. Adcock . Centro di Ricerca su ... Keywords:th2 cells, asthmatic airways, anti-asthmatic drugs, glucocorticoids, chemokines, immunomodulators. Abstract: The most ... Gaetano Caramori, Kazuhiro Ito and Ian M. Adcock, " Targeting Th2 Cells in Asthmatic Airways", Current Drug Targets - ... Some of these new Th2-oriented strategies may in the future not only control symptoms, but also potentially prevent or cure the ...
more infohttp://www.eurekaselect.com/91187/article
IJMS | Free Full-Text | Changes in the Ratio of Tc1/Tc2 and Th1/Th2 Cells but Not in Subtypes of NK-Cells in Preeclampsia  IJMS | Free Full-Text | Changes in the Ratio of Tc1/Tc2 and Th1/Th2 Cells but Not in Subtypes of NK-Cells in Preeclampsia
These results suggest that the type 1/type 2 immunity shifted totype 1 immunity including Th1 and Tc1 cells may contribute to ... In addition, the ratio of Th1/Th2 in peripheral blood alsoincreased. There was no significant difference of immunophenotypes of ... This study aimed to investigate theimmunophenotypes of NK cells and type 1/type 2 immunity in both decidua and ... Moreover, in preeclamptic patients, decreased percentages of Tc2 andTh2 cells and the increased ratios of Tc1/Tc2 were ...
more infohttps://www.mdpi.com/1422-0067/8/6/492
Novel Function of CRTH2 in Preventing Apoptosis of Human Th2 Cells through Activation of the Phosphatidylinositol 3-Kinase...  Novel Function of CRTH2 in Preventing Apoptosis of Human Th2 Cells through Activation of the Phosphatidylinositol 3-Kinase...
Although, like Th2 cells, Treg cells express both CD4 and CD25 and their growth is IL-2-dependent in culture, Treg cells are ... Apoptosis in Th2 cells induced by IL-2 deprivation is caspase dependent. Th2 cells were treated for 16 h in the presence or ... PGD2 suppresses apoptosis of human Th2 cells induced by IL-2 deprivation. A and B, Th2 cells were incubated in medium with or ... PGD2 has no effect on apoptosis of Th2 cells induced by Fas ligation. A and B, Th2 cells were treated with various ...
more infohttp://www.jimmunol.org/content/182/12/7580
IJMS | Free Full-Text | The Metalloporphyrin Antioxidant, MnTE-2-PyP, Inhibits Th2 Cell Immune Responses in an Asthma Model  IJMS | Free Full-Text | The Metalloporphyrin Antioxidant, MnTE-2-PyP, Inhibits Th2 Cell Immune Responses in an Asthma Model
... the addition of MnTE-2-PyP inhibited Th2 cell proliferation. MnTE-2-PyP suppressed CD25 expression on OVA-specific Th2 cells, ... MnTE-2-PyP-pretreated DC inhibited IL-4, IL-5 and IFNγ production and inhibited Th2 cell proliferation in the DC-Th2 co- ... Thus, we hypothesized that MnTE-2-PyP may alter dendritic cell-Th2 interactions. Bone marrow derived dendritic cells (DC) and ... which implied that MnTE-2-PyP can inhibit the activation of Th2 cells. MnTE-2-PyP also down-regulated co-stimulatory molecules ...
more infohttp://www.mdpi.com/1422-0067/13/8/9785
Th2 cells become IL-12 responsive following adoptive tr | Open-i  Th2 cells become IL-12 responsive following adoptive tr | Open-i
... in vitro Th2 cells or naïve CD4 cells were transferred to Rag1-/-mice fo ... Th2 cells become IL-12 responsive following adoptive transfer.A and B). CD4+Il4gfp+ ... Th2 cells become IL-12 responsive following adoptive transfer.A and B). CD4+Il4gfp+in vitro Th2 cells or naïve CD4 cells were ... Th2 cells become IL-12 responsive following adoptive transfer.A and B). CD4+Il4gfp+in vitro Th2 cells or naïve CD4 cells were ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC4493106_ppat.1004994.g007&req=4
Type 2 innate lymphoid cells drive CD4+ Th2 cell responses. - Semantic Scholar  Type 2 innate lymphoid cells drive CD4+ Th2 cell responses. - Semantic Scholar
By contrast, type 2 ILCs modulate naive T cell activation in a cell contact-dependent manner, favoring Th2 while suppressing ... However, the functional relationship between Th cells and innate lymphoid cells (ILCs) remains unclear. We show in this study ... In recent years, several subsets of innate lymphoid cell have been described as key producers of these same Th-associated ... CD4(+) T cell provision of IL-2 stimulates type 2 cytokine production by type 2 ILCs. ...
more infohttps://www.semanticscholar.org/paper/Type-2-innate-lymphoid-cells-drive-CD4%2B-Th2-cell-Mirchandani-Besnard/84d290ec96b6c0ef656ae2c538dd2504727b637e
The American Journal of Tropical Medicine and Hygiene | Circulating T Helper 1 (Th1) Cell- and Th2 Cell-Associated Cytokines in...  The American Journal of Tropical Medicine and Hygiene | Circulating T Helper 1 (Th1) Cell- and Th2 Cell-Associated Cytokines in...
... cell-(interferon-γ [IFN-γ]) and Th2 cell-associated cytokines (interleukin-4 [IL-4] and IL-10). The IFN-γ activity was detected ... These results using peripheral blood support the presence of a suppressive Th2 cell-associated immune response in symptomatic ... Circulating T Helper 1 (Th1) Cell- and Th2 Cell-Associated Cytokines in Indian Patients with Visceral Leishmaniasis * Shyam ... cell-(interferon-γ [IFN-γ]) and Th2 cell-associated cytokines (interleukin-4 [IL-4] and IL-10). The IFN-γ activity was detected ...
more infohttp://www.ajtmh.org/content/journals/10.4269/ajtmh.1997.56.522