One type of Th cell clone, Th1, causes delayed-type hypersensitivity (DTH) when injected with the appropriate Ag into the ... we have investigated the role of IFN-gamma in the DTH reaction induced by Th1 cells by using a mAb which neutralizes the ... The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones.. T A Fong and T R Mosmann ... Anti IFN-gamma inhibited up to 55% of the swelling response induced by seven Th1 clones in BALB/c and CBA/J mice suggesting ...

Cutting Edge: CD94/NKG2 Is Expressed on Th1 But Not Th2 Cells and Costimulates Th1 Effector Functions Jennifer Hartt Meyers, ... Dendritic Cell-Associated Lectin-1: A Novel Dendritic Cell-Associated, C-Type Lectin-Like Molecule Enhances T Cell Secretion of ... CD8 T Cell-Mediated Killing of Cryptococcus neoformans Requires Granulysin and Is Dependent on CD4 T Cells and IL-15 Ling Ling ... Adhesion of B Cell Lines to Endothelial Cells from Human Lymphoid Tissue Modulates Tyrosine Phosphorylation and Endothelial ...

Together with the fact that the expanded clones are activated in vivo and the corresponding clones belong to Th1 T cells, we ... or PLP-specific T cell clones and T cell infiltrates in MS brain lesions (4, 5). Repetitive acquisition of identical T cell ... T cell clones and lines (TCCL). A panel of CD4+ TCRαβ+ T cell clones and lines (TCCL) (Table I⇓) had previously been ... Lane 1, TCCL; lane 2, CD25+ T cells sorted from PBMC. B, Comparison of TCCL, CD25+ T cells, and CSF. Lane 1, CSF; lane 2, TCCL ...

... iTreg and Th17 cell differentiation, which is similar with Th1 cell differentiation but not Th2 cell differentiation (19, 21). ... nTreg cell. natural regulatory T cell. TβRI. TGF-β type I receptor. TβRII. TGF-β type II receptor. Treg cell. regulatory T cell ... cells were obtained by cell sorting (purity , 99%). To prepare naive CD4+CD25− cells, CD4+CD25− cells were labeled with PE- ... Treg cells and suppressing Th17 cells. A, Splenic CD4+CD25+CD62L+ cells sorted from WT and Smad3 KO mice (purity of both cell ...