It is therefore possible that most people exposed to HIV develop effective Th1 type responses and will not develop chronic ... Furthermore, many persons with HIV-associated B-cell polyclonal activation have been found to selectively switch off some or ... Infection with T. pallidum results in somewhat effective Th1 type responses in early syphilis, while immune deviation away from ... This latter response, coupled with the other down-regulation of Th1 DTH, is associated with chronic active infections, ...