Poly (ADP-ribose) polymerase - Wikipedia
RCSB PDB - 3TWV: Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human NUMA1 (chimeric peptide)
Tabalumab, an anti-BAFF monoclonal antibody, in patients with active rheumatoid arthritis with an inadequate response to TNF...
Programme and Venue | Instruct-ERIC Centre Finland Opening and Structural Biology Finland Conference 2021 | University of...
The Pawson Lab - Structural Basis for Cherubism Disease
Herpes simplex virus requires poly(ADP-ribose) polymerase activity for efficient replication and induces extracellular signal...
HSV did not replicate efficiently in cells depleted of both tankyrases 1 and 2. Moreover, XAV939, an inhibitor of tankyrase ... HSV did not replicate efficiently in cells depleted of both tankyrases 1 and 2. Moreover, XAV939, an inhibitor of tankyrase ... HSV did not replicate efficiently in cells depleted of both tankyrases 1 and 2. Moreover, XAV939, an inhibitor of tankyrase ... HSV did not replicate efficiently in cells depleted of both tankyrases 1 and 2. Moreover, XAV939, an inhibitor of tankyrase ...
![A New Synthesis of Poly Heterocyclic Compounds Containing [1,2,4]triazolo and [1,2,3,4]tetrazolo Moieties and their DFT Study...](data:image/png;base64,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)
A New Synthesis of Poly Heterocyclic Compounds Containing [1,2,4]triazolo and [1,2,3,4]tetrazolo Moieties and their DFT Study...
Haikarainen, T.; Krauss, S.; Lehtiö, L. Tankyrases: structure, function and therapeutic implications in cancer. Curr. Pharm. ... Several of important functions make Tankyrases acts as targets in potential drug. ... Several of important functions make Tankyrases acts as targets in potential drug. ... Screening and structural analysis of flavones inhibiting tankyrases. J. Med. Chem., 2013, 56(9), 3507-3517.[Available from. [ ...
DeCS 2019 - June 12, 2019 version
DeCS 2020 - June 23, 2020 version
DeCS 2016 - June 12, 2016 version
DeCS 2017 - July 04, 2017 version
DeCS 2018 - July 31, 2018 version
Telomerase. Medical search
Tankyrases. A group of telomere associated proteins that interact with TRF1 PROTEIN, contain ANKYRIN REPEATS and have poly(ADP- ... Long NoncodingProto-Oncogene Proteins c-mycKluyveromycesTankyrasesOxytrichaSouth CarolinaSoil Pollutants, RadioactiveMicroscopy ... Long NoncodingProto-Oncogene Proteins c-mycTankyrasesSoil Pollutants, Radioactive ...
Schüler, H.<...
Edward J Grow - Research output - University of Texas Southwestern Medical Center
Hendrickson, P. G., Doráis, J. A., Grow, E. J., Whiddon, J. L., Lim, J. W., Wike, C. L., Weaver, B. D., Pflueger, C., Emery, B. R., Wilcox, A. L., Nix, D. A., Peterson, C. M., Tapscott, S. J., Carrell, D. T. & Cairns, B. R., Aug 1 2017, In: Obstetrical and Gynecological Survey. 72, 8, p. 483-484 2 p.. Research output: Contribution to journal › Comment/debate › peer-review ...
UY-Lab Strand - Research output - University of Texas Southwestern Medical Center
Gerhauser, C., Favero, F., Risch, T., Simon, R., Feuerbach, L., Assenov, Y., Heckmann, D., Sidiropoulos, N., Waszak, S. M., Hübschmann, D., Urbanucci, A., Girma, E. G., Kuryshev, V., Klimczak, L. J., Saini, N., Stütz, A. M., Weichenhan, D., Böttcher, L. M., Toth, R., Hendriksen, J. D., & 35 othersKoop, C., Lutsik, P., Matzk, S., Warnatz, H. J., Amstislavskiy, V., Feuerstein, C., Raeder, B., Bogatyrova, O., Schmitz, E. M., Hube-Magg, C., Kluth, M., Huland, H., Graefen, M., Lawerenz, C., Henry, G. H., Yamaguchi, T. N., Malewska, A., Meiners, J., Schilling, D., Reisinger, E., Eils, R., Schlesner, M., Strand, D. W., Bristow, R. G., Boutros, P. C., von Kalle, C., Gordenin, D., Sültmann, H., Brors, B., Sauter, G., Plass, C., Yaspo, M. L., Korbel, J. O., Schlomm, T. & Weischenfeldt, J., Dec 10 2018, In: Cancer Cell. 34, 6, p. 996-1011.e8. Research output: Contribution to journal › Article › peer-review ...
Department of Systems Biology - Research output - Yonsei University
Exclusive destruction of mitotic spindles in human cancer cells | Oncotarget
Profile Treatment Approach Detail
Diamond Publications - Search Results
Ortunities for rising inhibitor selectivity.Aoyagi-Scharber et al.Acta Cryst. (2014). F70, 1143?BMNstructural communications4....
3b), which types -stacking interactions using the unique fluorophenyl group of BMN 673, is missing in PARP3 and tankyrases 1/2 ... The D-loop in PARP3 and tankyrases can also be shorter and assumes ?distinct conformations (Fig. 4a; Lehtio et al., 2009; ... Structural superposition indicates that the D-loop of PARP3 or tankyrases have to undergo conformational modifications so as to ...
Development of a 1,2,4-triazole-based lead tankyrase inhibitor: part II - MDC Repository
S-EPMC5337692 - RNF146 Inhibits Excessive Autophagy by Modulating the Wnt-?-Catenin Pathway in Glutamate Excitotoxicity Injury....
XAV-939 | PLA2 Signaling
3h). These data indicate that the catalytic activity of both tankyrases is required for the regulation of axin protein levels. ... Conditional knockout of both Tnks1 and Tnks2 will be important to understand the role of tankyrases in regulation of Wnt ... Using a chemical genetics approach, we have discovered tankyrases as novel targets for Wnt inhibition and described a novel ... Although the precise mech- anistic details remain unclear, tankyrases seem to promote the ubiqui- tination of axin, possibly ...
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