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*  Biomedicines | Free Full-Text | Decoding the Pluripotency Network: The Emergence of New Transcription Factors | HTML
... have been conducted to dissect the pluripotency network that governs the ability of these cells to differentiate into all cell ... In this review, we would like to summarize the recent advancements in the accumulating findings of new transcription factors ... Beside the core Oct4-Sox2-Nanog circuitry, accumulating regulators, including transcription factors, epigenetic modifiers, ... Since the successful isolation of mouse and human embryonic stem cells (ESCs) in the past decades, massive investigations ...
http://www.mdpi.com/2227-9059/1/1/49/htm
*  The function of the homeobox transcription factor Pitx2 during mammalian skeletal muscle development
Homeodomain transcription factors control developmental processes. They pattern body formation, specify cell lineages and ... DNA microarray analysis of limb pre-myogenic progenitor cells indicates that Pitx2 regulates several transcription factors and ... The function of the homeobox transcription factor Pitx2 during mammalian skeletal muscle development Public Deposited ... Pitx2, a bicoid-related homeodomain transcription factor, is asymmetrically expressed in the left lateral plate mesoderm and ...
https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/b5644w68k
*  Evolution of a species specific determinant essay topics, buy custom Evolution of a species specific determinant essay paper...
... some of the co-factors include the cyclin T1 (CycT1/CCNT1) transcription co-factor CD4 entry receptor and CCR5 co-receptor. ... During the improvement of VLP, the end result was a CTE-dependent nuclear export in 3T3 cells. The cells of a mouse cells that ... Expression of gag and elements of the virus were continuously reducing in production in 3T3 cells in relation to human cells as ... and various cellular factors are also partitioned so as to control the cell signaling and gene. CRM1 stresses on these roles ...
https://exclusivepapers.com/essays/analytical/evolution-of-a-species-specific-determinant.php
*  GCM1 glial cells missing transcription factor 1 [Homo sapiens (human)] - Gene - NCBI
glial cells missing transcription factor 1provided by HGNC. Primary source. HGNC:HGNC:4197 See related. Ensembl:ENSG00000137270 ... GCM1 glial cells missing transcription factor 1 [ Homo sapiens (human) ] Gene ID: 8521, updated on 23-Dec-2018 ... GCM1 glial cells missing transcription factor 1 [Homo sapiens] GCM1 glial cells missing transcription factor 1 [Homo sapiens]. ... New insights into the regulation of placental growth factor gene expression by the transcription factors GCM1 and DLX3 in human ...
https://www.ncbi.nlm.nih.gov/gene/8521
*  Undifferentiated embryonic cell transcription factor 1
Found nearly exclusively in pluripotent cells, this protein can also serve as a transcriptional repressor. [provided by RefSeq ... a leucine zipper-containing transcriptional coactivator that may link the upstream activator ATF2 with the basal transcription ... associated with chromatin and is required for the proper differentiation of embryonic carcinoma and embryonic stem cells. ... HCA RNA Cell Line for Undifferentiated embryonic cell transcription factor 1. AN3-CA 15,648 ...
https://pharos.nih.gov/idg/targets/UTF1
*  Value of thyroid transcription factor-1 immunostaining in distinguishing small cell lung carcinomas from other small cell...
... and small cell carcinomas of other sites is difficult ... The distinction between small cell lung carcinoma (SCLC) ... and small cell carcinomas of other sites is difficult by routine histology. Thyroid transcription factor-1 (TTF-1) is a ... a marker that has previously been demonstrated in small cell carcinomas of the skin (Merkel cell carcinomas), in 82 small cell ... homeodomain-containing transcription factor that is selectively expressed in thyroid and pulmonary epithelial cells. TTF-1 ...
https://avmi.net/information/hyperthyroid-hints/value-of-thyroid-transcription-factor-1-immunostaining-in-distinguishing-small-cell-lung-carcinomas-from-other-small-cell-carcinomas/
*  The transcription factor XBP-1 is essential for the development and survival of dendritic cells | JEM
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat. Immunol. 4:321- ... Transcription factor GATA-3 is required for development of the T-cell lineage. Nature. 384:474-478. ... XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell ... Towards an understanding of the transcription factor network of dendritic cell development. Trends Immunol. 27:140-145. ...
http://jem.rupress.org/content/204/10/2267
*  The Ets-1 transcription factor controls the development and function of natural regulatory T cells | JEM
Regulatory T cells (T reg cells) constitute a population of CD4+ T cells that limits immune responses. The transcription factor ... Conversion of peripheral CD4+CD25− naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor ... called regulatory T cells (T reg cells), which is characterized by the transcription factor Foxp3 (Fontenot et al., 2003; Hori ... Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells. J. Exp ...
http://jem.rupress.org/content/early/2010/09/15/jem.20092153
*  Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line. |...
Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line.. ... Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line. ... Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line. ... Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line. ...
https://mcb.asm.org/content/17/3/1642.long
*  Thyroid Transcription Factor-1 Activity Is Required For the Proliferation of Human Thyroid Cancer Cells 8505C - Thyroid...
... raising a question about the role of the factor in these cells. In order to investigate this point, we used a chimeric protein ... We observed a growth arrest of 8505C thyroid cancer cells when the endogenous TTF-1 transcriptional activity was inhibited. It ... Many human thyroid cancer cell lines keep producing TTF-1 despite the loss of differentiated gene expression, ... in thyroid cell proliferation and in the expression of genes involved in thyroid differentiated function. ...
https://openaccesspub.org/jtc/article/230
*  The role of AP-1 family transcription factor networks in regulating Th17 cell identity | The Journal of Immunology
CD4 T cells can adopt one of two opposing fates: a helper T cell (Th) specialized in supporting pathogen clearance, or a ... IL-17A-producing inflammatory Th17 cells stand out among Th cells, possessing a high level of inherent plasticity in response ... Increased generation of regulatory T cells in the presence of reduced T cell receptor signaling capacity correlates with a ... Here, we (i) use fate-mapping reporter mice to dissect the requirement for JunB in maintaining Th17 cell stability, (ii) define ...
http://www.jimmunol.org/content/196/1_Supplement/204.30
*  Interferon-gamma signaling in human retinal pigment epithelial cells mediated by STAT1, ICSBP, and IRF-1 transcription factors....
RESULTS: HRPE cells constitutively expressed two members of the IFN regulatory factor (IRF) family of transcription factors, ... suggesting that it may regulate gene transcription in RPE cells and possibly in other nonimmunologic cell types. ... METHODS: RNA, whole-cell extracts, and nuclear extracts were prepared from HRPE cells cultured in the presence or absence of ... ICSBP is thought to be exclusively used in immunologic responses and has previously been detected only in lymphoid cells. ...
https://iovs.arvojournals.org/article.aspx?articleid=2162065
*  Functional dissection of AP-1 transcription factors using the Gal4 adaptor assay -- Smith and Bohmann 3 (8): 523 -- Cell Growth...
Cell Growth & Differentiation, Vol 3, Issue 8 523-529, Copyright © 1992 by American Association of Cancer Research ... Cell Growth & Differentiation. Copyright © 1992 by the American Association of Cancer Research. ... Ternary complexes composed of the DNA binding site, the adaptor protein, and a leucine zipper factor can stimulate reporter ... This system is used to assay the transcriptional function and the interactions between various AP-1 factors. This article has ...
http://cgd.aacrjournals.org/cgi/content/abstract/3/8/523
*  Overexpression of heat shock transcription factor 1 enhances the resistance of melanoma cells to doxorubicin and paclitaxel |...
Cells overexpressing a full or dominant negative form of HSF1, but not a constitutively active one, had higher transcription ... Cell cultures were treated with increasing amounts of doxorubicin, paclitaxel, cisplatin, vinblastine or bortezomib. Cell ... Cellular accumulation of fluorescent dyes and side population cells were studied using flow cytometry. Cells overexpressing ... The aim of the present study was to determine whether HSF1 could have an effect on the survival of cancer cells treated with ...
https://0-bmccancer-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2407-13-504
*  The transcription factor Ap-1 regulates monkey 20α-hydroxysteroid dehydrogenase promoter activity in CHO cells | BMC...
Thus, we demonstrated that monkey 20α-HSD promoter activity is regulated by the transcription factor Ap-1 in CHO-K1 cells. ... K1 cells. A reporter assay using constructs of various lengths of the 5′-flanking region (-890-Luc, -513-Luc, -306-Luc, -273- ... the transcription activities of the constructs increased with the exception of -273 and -70, while that of the double construct ... 273-Luc dramatically decreased the transcription levels to the control levels. When the reporter constructs were co-transfected ...
https://bmcbiotechnol.biomedcentral.com/articles/10.1186/1472-6750-14-71
*  Substance P induced biosynthesis of the zinc finger transcription factor Egr-1 in human glioma cells requires activation of the...
... cells as a result of substance P stimulation suggests that substance P exerts long-term effects in glioma cells via Egr-1- ... an epidermal growth factor (EGF) receptor-specific tyrosine kinase inhibitor. These results indicate that transactivation of ... Substance P-induced stimulation of Egr-1 biosynthesis was completely inhibited by the mitogen-activated protein kinase kinase ... are essential for substance P/NK-1 receptor-induced activation of Egr-1 biosynthesis. Moreover, we show that the signaling ...
https://www.semanticscholar.org/paper/Substance-P-induced-biosynthesis-of-the-zinc-finge-Al-Sarraj-Thiel/6b3c435d7ed102f0d659161dc5dae417fc70a53a
*  Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel...
Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel ... Using the Transcription Factor Inhibitor of DNA Binding 1 to Selectively Target Endothelial Progenitor Cells Offers Novel ... Using the Transcription Factor Inhibitor of DNA Binding 1 to Selectively Target Endothelial Progenitor Cells Offers Novel ... Using the Transcription Factor Inhibitor of DNA Binding 1 to Selectively Target Endothelial Progenitor Cells Offers Novel ...
https://www.ncbi.nlm.nih.gov/pubmed/20807818
*  The Transcription Factor Fos-Related Antigen 1 Is Induced by Thiazolidinediones During Differentiation of 3T3-L1 Cells |...
1993) The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature (Lond) 365: ... 1994b) Stimulation of adipogenesis in fibroblasts by PPAR-gamma-2, a lipid-activated transcription factor. Cell 79:1147-1156. ... 1999) Target genes of beta-catenin-T cell-factor lymphoid-enhancer-factor signaling in human colorectal carcinomas. Proc Natl ... the testis-determining factor Sry (Cohen et al., 1994) and the transcription factor Tax-1 of the human T-cell leukemia virus ...
http://molpharm.aspetjournals.org/content/59/3/567
*  The transcription factor Ap-1 regulates monkey 20α-hydroxysteroid dehydrogenase promoter activity in CHO cells - pdf descargar
The transcription factor Ap-1 regulates monkey 20α-hydroxysteroid dehydrogenase promoter activity in CHO cells. . Biblioteca ... The transcription factor Ap-1 regulates monkey 20α-hydroxysteroid dehydrogenase promoter activity in CHO cells - Descarga este ... Thus, we demonstrated that monkey 20α-HSD promoter activity is regulated by the transcription factor Ap-1 in CHO-K1 cells.. ... The transcription factor Ap-1 regulates monkey 20α-hydroxysteroid dehydrogenase promoter activity in CHO cells. ...
http://libros.duhnnae.com/2017/jul4/14991136040-The-transcription-factor-Ap-1-regulates-monkey-20-hydroxysteroid-dehydrogenase-promoter-activity-in-CHO-cells.php
*  Review. iPS cells: opportunities and challenges | Philosophical Transactions of the Royal Society B: Biological Sciences
Somatic cells have been reprogrammed into pluripotent stem cells by introducing a combination of several transcription factors ... 2007 Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872. doi:10.1016/j.cell ... 2009 Generation of induced pluripotent stem cell lines from adult rat cells. Cell Stem Cell 4, 11-15. doi:10.1016/j.stem. ... 2008 Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages. Cell Stem Cell 3, ...
http://rstb.royalsocietypublishing.org/content/366/1575/2198
*  Involvement of oxidants and AP-1 in angiotensin II-activated NFAT3 transcription factor | Cell Physiology
Activation of several transcription factors, including the nuclear factor of activated T cells-3 (NFAT3), contributes in part ... Activation of the nuclear factor of activated T cells-3 (NFAT3) transcription factor has been shown to result from endocrine ... Antioxidants inhibit ANG II from activating nuclear factor of activated T cells-3 (NFAT3) transcription factor in ... EMSA was used to verify the activation of NFAT3 transcription factor. The binding of NFAT3 transcription factor to its cis- ...
http://ajpcell.physiology.org/content/292/4/C1248
*  Cardiac transcription factors in HL-1 cells: genome binding profiling | Stem Cell Commons
2003) Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic ... and TRE promoter driving transcription factor Gata4 or Mef2a or Nkx2-5 or Srf or Tbx5 as indicated for 48 hrs before cells ... We performed bio-ChIP-seq using streptavidin beads immunoprecipitation of biotinylated 5 cardiac transcription factors (fbio) ... Genome occupancy profiling: Identify cardiac active enhancers by identified 5 cardiac transcription factors and P300 peaks. ...
http://stemcellcommons.org/node/16436
*  Phosphorylation of EGFR, ERK 1/2 and downstream transcription factors after P2Y2 receptor activation in a human submandibular...
HSG cells, which endogenously express P2Y2 receptors and are derived from a human submandibular gland tumor, were utilized as a ... and the downstream transcription factors p90RSK, and ELK, suggesting that P2Y2 receptors may play a role in gene transcription ... Our results show that UTP, the P2Y2 receptor selective agonist, causes phosphorylation of the epidermal growth factor receptor ... cell model to analyze downstream signaling pathways in response to UTP. ...
https://mospace.umsystem.edu/xmlui/handle/10355/1563
*  Abstract 190: Purinergic Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: New AP-1 Site and...
Abstract 190: Purinergic Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: New AP-1 Site and ... Abstract 190: Purinergic Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: New AP-1 Site and ... Abstract 190: Purinergic Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: New AP-1 Site and ... Abstract 190: Purinergic Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: New AP-1 Site and ...
http://atvb.ahajournals.org/content/35/Suppl_1/A190
*  TIMP-1 induces an epithelial mesenchymal transition via upregulation of the transcription factor Twist in human breast...
... an epithelial mesenchymal transition via upregulation of the transcription factor Twist in human breast epithelial cells. ... a transcription factor known to suppress E-cadherin gene transcription and upregulate mesenchymal markers. SiRNA-mediated Twist ... an epithelial mesenchymal transition via upregulation of the transcription factor Twist in human breast epithelial cells ... an epithelial mesenchymal transition via upregulation of the transcription factor Twist in human breast epithelial cells ...
http://cancerres.aacrjournals.org/content/68/9_Supplement/5374