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*  Extrasynaptic NR2D-containing NMDARs are recruited to the synapse during LTP of NMDAR-EPSCs
Long-term potentiation of NMDA-receptor-mediated synaptic transmission (NMDAR-LTP) is a little-understood form of plasticity. ... Our results show that LTP of NMDAR-EPSCs involves movement of NMDARs from an extrasynaptic to a synaptic location and suggest a ... Activation of extrasynaptic NMDARs after glutamate uptake inhibition also occurred when synaptic NMDARs were inhibited with ... Further studies using selective antagonists for NR2A- and NR2B-containing NMDARs demonstrated that synaptic NMDARs are ...
http://www.tara.tcd.ie/handle/2262/40186
*  Neurotransmitter Secretion along Growing Nerve Processes: Comparison with Synaptic Vesicle Exocytosis | JCB
Maturation of this machinery in the process of synaptic development would improve the fidelity of synaptic transmission during ... 1992) Elementary steps in synaptic transmission revealed by currents through single ion channels. Neuron 8:613-629, pmid: ... which is essential for the fidelity of synaptic transmission during the high-frequency excitation of the presynaptic cell. ... ARF1 and AP-3 coat complex are involved in formation of synaptic vesicles from endosomes, whereas formation of synaptic ...
http://jcb.rupress.org/content/144/3/507
*  Frontiers | Dopamine regulates intrinsic excitability thereby gating successful induction of spike timing-dependent plasticity...
To better understand signaling mechanisms and involvement of neuromodulators such as dopamine in synaptic plasticity, less ... To better understand signaling mechanisms and involvement of neuromodulators such as dopamine in synaptic plasticity, less ... Physiological relevant amount of activation can be used to induce long-lasting plastic changes in synaptic transmission. This ... Most of those substances activate G-protein coupled receptors and alter synaptic transmission or ionic conductions. Examples ...
https://www.frontiersin.org/articles/10.3389/fnins.2013.00025/full
*  The AMPA Receptor Steps out of the Shadows | ALZFORUM
... three AMPA subunits were present in the mice and combined to allow the receptor to function normally in synaptic transmission. ... Upon synaptic stimulation to induce LTP, they were able to observe rapid delivery of tagged AMPA receptors into clusters in the ... Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning. Science. 1999 Jun 11;284(5421): ... Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation. Science. 1999 Jun 11;284( ...
http://www.alzforum.org/news/research-news/ampa-receptor-steps-out-shadows
*  8.4 Synaptic transmission IV - Synaptic transmission & Synapitic plasticity | Coursera
Let's continue with synaptic transmission and synapitic plasticity. Learn online and earn valuable credentials from top ... 8.4 Synaptic transmission IV. To view this video please enable JavaScript, and consider upgrading to a web browser that ... we see the post-synaptic response and we know they are sensitive to glutamate. ... Synaptic transmission & Synapitic plasticity. Let's continue with synaptic transmission and synapitic plasticity. ...
https://www.coursera.org/lecture/advanced-neurobiology1/8-4-synaptic-transmission-iv-2OWep
*  9.6 Synapitic plasticity VI - Synaptic transmission & Synapitic plasticity | Coursera
Let's continue with synaptic transmission and synapitic plasticity. Learn online and earn valuable credentials from top ... Synaptic transmission & Synapitic plasticity. Let's continue with synaptic transmission and synapitic plasticity. ...
https://www.coursera.org/lecture/advanced-neurobiology1/9-6-synapitic-plasticity-vi-bscCh?authMode=signup
*  9.4 Synapitic plasticity IV - Synaptic transmission & Synapitic plasticity | Coursera
Let's continue with synaptic transmission and synapitic plasticity. Learn online and earn valuable credentials from top ... Okay, so neurons, firing together, then their synaptic strains will be fully enhanced, and this is called firing together, ... this is synaptic input this delta T is minus 0, and sometimes the spike can ... But during this time, there's one synaptic input coming from this presynaptic neuron. ...
https://www.coursera.org/lecture/advanced-neurobiology1/9-4-synapitic-plasticity-iv-9jsHT
*  8.3 Synaptic trasmission III - Synaptic transmission & Synapitic plasticity | Coursera
Let's continue with synaptic transmission and synapitic plasticity. Learn online and earn valuable credentials from top ... 8.3 Synaptic trasmission III. To view this video please enable JavaScript, and consider upgrading to a web browser that ... in tact they can integrate it in a post synaptic cells.. For example you active this a cell and then you would record in a post ... Synaptic transmission & Synapitic plasticity. Let's continue with synaptic transmission and synapitic plasticity. ...
https://www.coursera.org/lecture/advanced-neurobiology1/8-3-synaptic-trasmission-iii-54Vyz
*  PPT - Synaptic transmission PowerPoint Presentation - ID:520144
Synaptic transmission)4.1 ?????????????????????????????????? (Anatomy and types of synapse)4.2 ... Synaptic Transmission -2010 - lecture 6 chapter 4 neural condition: synaptic transmission. chemical transmission transmitting ... Lecture 4: Synaptic Transmission. -Biological bases of behaviour. lecture 4: synaptic transmission. learning outcomes. at the ... Lecture 19 Synaptic transmission, vesicle fusion and cycling Why selectivity may not be important? -Lecture 19 synaptic ...
https://www.slideserve.com/rigg/synaptic-transmission
*  Role of CNTNAP2 in neuronal structural development and synaptic transmission | Autism Speaks
Autism SpeaksScienceGrant SearchResultsRole of CNTNAP2 in neuronal structural development and synaptic transmission ... resulting in abnormal synaptic transmission as a result. This study expands upon this initial finding by thoroughly evaluating ... CNTNAP2 function in governing neuronal development and synaptic transmission using morphological and electrophysiological ... and NMDA-receptor mediated synaptic responses at excitatory synapses onto CA1 pyramidal cells. The goal of this study is to ...
https://www.autismspeaks.org/science/grants/role-cntnap2-neuronal-structural-development-and-synaptic-transmission?destination=about-us%2Fgrant-search-location%2Fresults%2Fneurons+taxonomy%3A9771%2C10736
*  Slow synaptic transmission in frog sympathetic ganglia | Journal of Experimental Biology
Slow synaptic transmission in frog sympathetic ganglia. P. R. Adams, S. W. Jones, P. Pennefather, D. A. Brown, C. Koch, B. ... Slow synaptic transmission in frog sympathetic ganglia. P. R. Adams, S. W. Jones, P. Pennefather, D. A. Brown, C. Koch, B. ... Slow synaptic transmission in frog sympathetic ganglia. P. R. Adams, S. W. Jones, P. Pennefather, D. A. Brown, C. Koch, B. ... Slow synaptic transmission in frog sympathetic ganglia Message Subject (Your Name) has sent you a message from Journal of ...
http://jeb.biologists.org/content/124/1/259
*  Bidirectional Dopaminergic Modulation of Excitatory Synaptic Transmission in Orexin Neurons | Journal of Neuroscience
Bidirectional Dopaminergic Modulation of Excitatory Synaptic Transmission in Orexin Neurons. Christian O. Alberto, Robert B. ... Bidirectional Dopaminergic Modulation of Excitatory Synaptic Transmission in Orexin Neurons. Christian O. Alberto, Robert B. ... Bath application of DA induced a bidirectional effect on the excitatory synaptic transmission dose dependently. A low dose of ... Bidirectional Dopaminergic Modulation of Excitatory Synaptic Transmission in Orexin Neurons Message Subject (Your Name) has ...
http://www.jneurosci.org/content/26/39/10043
*  Synaptic Transmission, part 2 - Neural Signaling: Synaptic Transmission and Synaptic Plasticity | Coursera
Let's continue our studies of neural signaling by learning about what happens at synaptic junctions, where the terminal ending ... Neural Signaling: Synaptic Transmission and Synaptic Plasticity. Let's continue our studies of neural signaling by learning ... synaptic transmission, post synaptic mechanisms of signal integration, and neural plasticity. - Unit 3 Sensory systems (weeks 5 ... Synaptic Transmission, part 2. To view this video please enable JavaScript, and consider upgrading to a web browser that ...
https://www.coursera.org/lecture/medical-neuroscience/synaptic-transmission-part-2-JO6iE
*  Stress and steroid regulation of synaptic transmission: from physiology to pathophysiology
... Journal. Frontiers in Cellular ... Stress_and_steroid_regulation_of_synaptic_transmission_from_physiology_to_pathophysiology.pdf. ...
http://dare.uva.nl/search?metis.record.id=382277
*  PPT - Synapses and Synaptic Transmission PowerPoint Presentation - ID:529606
For different types of neurons, there may be only a few hundred or as many as 200,000 such synaptic conn Slideshow 529606 by ... Lecture 4: Synaptic Transmission. -Biological bases of behaviour. lecture 4: synaptic transmission. learning outcomes. at the ... ca 2 +. synaptic transmission. how is synaptic transmission affected by activity? mechanism functional consequences. epsp + ... Anagnostaras -. lecture 5 synaptic transmission. introduction to synaptic transmission. synapses (gk., to clasp or join) site ...
https://www.slideserve.com/yoshino/synapses-and-synaptic-transmission
*  Direct Measurement of AMPA Receptor Desensitization Induced by Glutamatergic Synaptic Transmission | Journal of Neuroscience
1995) AMPA receptors with high Ca2+ permeability mediate synaptic transmission in the auditory pathway. J Physiol (Lond) 482: ... Direct Measurement of AMPA Receptor Desensitization Induced by Glutamatergic Synaptic Transmission. Thomas Otis, Su Zhang, ... Direct Measurement of AMPA Receptor Desensitization Induced by Glutamatergic Synaptic Transmission. Thomas Otis, Su Zhang, ... 1996) Monte Carlo simulation of fast excitatory synaptic transmission at a hippocampal synapse. J Neurophysiol 75:597-608. ...
http://www.jneurosci.org/content/16/23/7496
*  Long-Term Depression of Excitatory Synaptic Transmission in the Rat Amygdala | Journal of Neuroscience
Long-Term Depression of Excitatory Synaptic Transmission in the Rat Amygdala Message Subject (Your Name) has forwarded a page ... Long-Term Depression of Excitatory Synaptic Transmission in the Rat Amygdala. Su-Jane Wang and Po-Wu Gean ... A, Synaptic responses recorded before and 40 min after LFS in a BLA neuron. B, Electrotonic potentials recorded as a result of ... A, Okadaic acid (1 μm) on its own did not significantly affect synaptic responses. However, in the presence of okadaic acid, ...
http://www.jneurosci.org/content/19/24/10656/tab-figures-data
*  6.2 The Na+ gating current - Ion channels, membrane potential and synaptic transmission | Coursera
... membrane potential and synaptic transmission. 2000+ courses from schools like Stanford and Yale - no application required. ... 6.4 Ion channel, membrane potential and synaptic transmission I15:12. 6.5 Ion channel, membrane potential and synaptic ... 6.6 Ion channel, membrane potential and synaptic transmission III12:53. 6.7 Ion channel, membrane potential and synaptic ... membrane potential and synaptic transmission. Let's continue with the ion channels, membrane potential and synaptic ...
https://www.coursera.org/learn/advanced-neurobiology1/lecture/mYcFV/6-2-the-na-gating-current
*  Maturation of Synaptic Transmission at End-Bulb Synapses of the Cochlear Nucleus | Journal of Neuroscience
We studied developmental changes in synaptic transmission that enable the end-bulb synapse to function as a synaptic relay. In ... Maturation of Synaptic Transmission at End-Bulb Synapses of the Cochlear Nucleus. Stephan Brenowitz and Laurence O. Trussell ... Under voltage clamp, transmission at the embryonic synapse in nMag is characterized by strong depression of synaptic currents ( ... 1994a) Voltage clamp analysis of excitatory synaptic transmission in the avian nucleus magnocellularis. J Physiol (Lond) 480: ...
http://www.jneurosci.org/content/21/23/9487
*  Peripherally restricted viral challenge elevates extracellular glutamate and enhances synaptic transmission in the hippocampus....
Synaptic transmission in hippocampal slices. Mice were intraperitoneally injected with PIC or saline (control), and after 24 h ... b) Basic synaptic transmission as the fEPSP slope measured at increasing stimulus intensity (c) Paired-pulse facilitation ... Peripherally restricted viral challenge elevates extracellular glutamate and enhances synaptic transmission in the hippocampus. ... Peripherally restricted viral challenge elevates extracellular glutamate and enhances synaptic transmission in the hippocampus ...
https://www.ncbi.nlm.nih.gov/pubmed/27168075
*  Nitric Oxide Signaling Modulates Synaptic Transmission during Early Postnatal Development
... synaptic transmission and correlated neuronal activity are fundamental to network formation; however, their regulation during ... Early γ-aminobutyric acid mediated (GABAergic) synaptic transmission and correlated neuronal activity are fundamental to ... evidence-using whole-cell recording-that NO signaling modulates not only glutamatergic but also GABAergic synaptic transmission ...
https://insights.ovid.com/cerebral-cortex/cecor/2011/09/000/nitric-oxide-signaling-modulates-synaptic/15/00008354
*  GABAB Receptor-Mediated Inhibition of Synaptic Transmission in the Hippocampus: Pharmacology and Intracellular Mechanisms |...
Dutar P, Rascol O, Lamour Y (1989): ω-conotoxin GVIA blocks synaptic transmission in the CA1 field of the hippocampus. Eur J ... Nicoli RA, Dutar P (1989): Physiological roles of GABAA and GABAB receptors in synaptic transmission in the hippocampus. In: ... Scholz KP, Miller RJ (1991): GABAB receptor-mediated inhibition of Ca2+ currents and synaptic transmission in cultured rat ... Horne AL, Kemp JA (1991): The effect of ω-conotoxin GVIA on synaptic transmission within the nucleus accumbens and hippocampus ...
https://link.springer.com/chapter/10.1007/978-1-4684-6825-0_2
*  Pharmacological characterization of calcium currents and synaptic transmission between thalamic neurons in vitro | Journal of...
Pharmacological characterization of calcium currents and synaptic transmission between thalamic neurons in vitro. FW Pfrieger, ... Pharmacological characterization of calcium currents and synaptic transmission between thalamic neurons in vitro ... Pharmacological characterization of calcium currents and synaptic transmission between thalamic neurons in vitro ... Pharmacological characterization of calcium currents and synaptic transmission between thalamic neurons in vitro ...
http://www.jneurosci.org/content/12/11/4347
*  JCI - Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in...
... receptor-mediated synaptic transmission in mouse hippocampal slices but failed to inhibit synaptic responses in slices from ... JAK2 and PI3K antagonists prevented leptin inhibition of AMPAergic synaptic transmission. We conclude that leptin receptor ... Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents. ... Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents. ...
https://www.jci.org/articles/view/33009/figure/2
*  Presynaptic cell type-dependent regulation of GABAergic synaptic transmission by nitric oxide in rat insular cortex. - PubMed ...
Presynaptic cell type-dependent regulation of GABAergic synaptic transmission by nitric oxide in rat insular cortex.. Yamamoto ... Nitric oxide (NO) is a key retrograde messenger that regulates synaptic transmission in the cerebral cortex. However, little is ... These results suggest that NO regulation of inhibitory synaptic transmission is dependent on presynaptic cell subtypes and that ... known about NO-induced modulatory effects and their mechanisms relative to inhibitory synaptic transmission. The present study ...
https://www.ncbi.nlm.nih.gov/pubmed/25286388?dopt=Abstract