Probable succinate-semialdehyde dehydrogenase elisa and antibody
Recombinant Protein and Probable succinate-semialdehyde dehydrogenase Antibody at MyBioSource. Custom ELISA Kit, Recombinant ... Probable succinate-semialdehyde dehydrogenase [NADP. Probable succinate-semialdehyde dehydrogenase [NADP ELISA Kit. Probable ... Probable succinate-semialdehyde dehydrogenase [NADP Antibody. Also known as Probable succinate-semialdehyde dehydrogenase [NADP ... dependent oxidation of succinate semialdehyde to succinate.. Below are the list of possible Probable succinate-semialdehyde ...https://www.mybiosource.com/protein_family.php?root=probable-succinate-semialdehyde-dehydrogenase
Succinic semialdehyde dehydrogenase deficiency - Wikipedia
2002). "Focal neurometabolic alterations in mice deficient for succinate semialdehyde dehydrogenase". Journal of Neurochemistry ... "Therapeutic concepts in succinate semialdehyde dehydrogenase (SSADH; ALDH5a1) deficiency (γ-hydroxybutyric aciduria). ... Succinic semialdehyde dehydrogenase deficiency (SSADHD), also known as 4-hydroxybutyric aciduria or gamma-hydroxybutyric ... Succinate semialdehyde is considered a reactive carbonyl and may lead to increased oxidative stress. This stress is believed to ...https://en.wikipedia.org/wiki/Gamma-hydroxybutyric_aciduria
Succinic semialdehyde dehydrogenase deficiency - Wikipedia
2002). "Focal neurometabolic alterations in mice deficient for succinate semialdehyde dehydrogenase". Journal of Neurochemistry ... "Therapeutic concepts in succinate semialdehyde dehydrogenase (SSADH; ALDH5a1) deficiency (γ-hydroxybutyric aciduria). ... Succinate semialdehyde is considered a reactive carbonyl and may lead to increased oxidative stress. This stress is believed to ... Finally, succinic semialdehyde dehydrogenase levels can be measured in cultured leukocytes of the patient. This occurs due to ...https://en.wikipedia.org/wiki/Succinic_semialdehyde_dehydrogenase_deficiency
Remediated Sequence - 4ITA: Structure of bacterial enzyme in complex with cofactor Sequence Report Page
Structural Basis for a Cofactor-dependent Oxidation Protection and Catalysis of Cyanobacterial Succinic Semialdehyde ... Chain A: Succinate-semialdehyde dehydrogenase. Chain Downloadable Files. Download FASTA File. View Sequence & DSSP Image. ... Chain B: Succinate-semialdehyde dehydrogenase. Chain Downloadable Files. Download FASTA File. View Sequence & DSSP Image. ...http://www.rcsb.org/pdb/explore/remediatedSequence.do?params.chainEntityStrategyStr=all&structureId=4ITA&forcePageForChain=¶ms.chainsPerPage=10
succinate semialdehyde dehydrogenase. Gene Start:. 1021611. Gene Stop:. 1020181. Gene Length:. 1431. Molecular Weight*:. 50999 ... NG1061 also has very strong (P-value < 1e-100) similarity to succinate semialdehyde dehydrogenase proteins in several other ... NG1061 is orthologous to AL162756, N. meningitidis Z2491 succinate semialdehyde dehydrogenase: residues 1-477 have 96% ... From GenBANK (gi:120777): GabD of E. coli catalyzes the reaction: succinate semialdehyde + NADP(+) + H2O = succinate + NADPH, ...http://stdgen.northwestern.edu/cgi-bin/gene_id_search.cgi?dbname=ngon&gene_id=NG1061
MetReconIssues | Systems Biology Research Group
... prediction and experimental verification of the gene encoding the NAD+/NADP+-dependent succinate semialdehyde dehydrogenase in ... 2003). "Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643." J Biol Chem 278( ...http://systemsbiology.ucsd.edu/InSilicoOrganisms/OtherOrganisms/MetReconIssues
Brain Excitability in Patients With Succinic Semialdehyde Dehydrogenase Deficiency - Full Text View - ClinicalTrials.gov
Mutational spectrum of the succinate semialdehyde dehydrogenase (ALDH5A1) gene and functional analysis of 27 novel disease- ... succinic semialdehyde dehydrogenase deficiency Genetic and Rare Diseases Information Center resources: Succinic Semialdehyde ... Documented succinic semialdehyde dehydrogenase enzyme deficiency. *English-speaking (or the ability to understand English as a ... Brain Excitability in Patients With Succinic Semialdehyde Dehydrogenase Deficiency. This study has been completed. ...https://clinicaltrials.gov/ct2/show/NCT00132366?cond=%22argininosuccinic+aciduria%22+OR+%22amino+acid+metabolism%2C+inborn+errors%22&rank=11
Succinate semialdehyde dehydrogenase definition | Drugs.com
Definition of succinate semialdehyde dehydrogenase. Provided by Stedman's medical dictionary and Drugs.com. Includes medical ... succinate semialdehyde dehydrogenase. Definition: an enzyme that catalyzes the reaction of succinate semialdehyde and either ... NAD+ or NADP+ to form succinate and NADH (or NADPH); a deficiency of this enzyme is associated with 4-hydroxybutyric aciduria. ...https://www.drugs.com/dict/succinate-semialdehyde-dehydrogenase.html
Succinate-semialdehyde dehydrogenase - Wikipedia
... succinic semialdehyde dehydrogenase, succinyl semialdehyde dehydrogenase, and succinate semialdehyde:NAD+ oxidoreductase. This ... a succinate-semialdehyde dehydrogenase (SSADH) (EC 184.108.40.206) is an enzyme that catalyzes the chemical reaction succinate ... Succinate-semialdehyde dehydrogenase is found in organisms ranging across the tree of life from bacteria to humans. It is ... Other names in common use include succinate semialdehyde dehydrogenase, ...https://en.wikipedia.org/wiki/Succinate-semialdehyde_dehydrogenase
Succinate-semialdehyde dehydrogenase (acylating) - Wikipedia
... coenzyme-A-dependent succinate-semialdehyde dehydrogenase) is an enzyme with systematic name succinate semialdehyde:NADP+ ... Succinate-semialdehyde dehydrogenase (acylating) at the US National Library of Medicine Medical Subject Headings (MeSH) ... Succinate-semialdehyde dehydrogenase (acylating) (EC 220.127.116.11, succinyl-coA reductase, ... "Purification and characterization of a coenzyme-A-dependent succinate-semialdehyde dehydrogenase from Clostridium kluyveri". ...https://en.wikipedia.org/wiki/Succinate-semialdehyde_dehydrogenase_(acylating)
Comparative genomics of aldehyde dehydrogenase 5a1 (succinate semialdehyde dehydrogenase) and accumulation of gamma...
... represent two neural enzymes responsible for further catabolism of succinic semialdehyde, producing either succinate (SSADH) or ... aldehyde dehydrogenase 5A1 [ALDH5A1]; locus 6p22) occupies a central position in central nervous system (CNS) neurotransmitter ... Comparative genomics of aldehyde dehydrogenase 5a1 (succinate semialdehyde dehydrogenase) and accumulation of gamma- ... and aldehyde dehydrogenase 5A1 (ALDH5A1; succinate semialdehyde dehydrogenase [SSADH]) (Figures 1 and 2). Human disorders of ...https://humgenomics.biomedcentral.com/articles/10.1186/1479-7364-3-2-106
Computational prediction and experimental verification of the gene encoding the NAD(+)/NADP(+)-dependent succinate semialdehyde...
... dependent succinate semialdehyde dehydrogenase in Escherichia coli. * Mendeley ...https://www.research-collection.ethz.ch/handle/20.500.11850/4126
Glutamate/GABA Synthesis and Metabolism | Sigma-Aldrich
Succinate semialdehyde. │ │---------------→. │. ↓. Succinate semialdehyde dehydrogenase. NADH (N8129). Succinate semialdehyde. ... Succinate semialdehyde dehydrogenase. Brain, liver and other tissues. GABA metabolism (GABA-shunt). Not known. ... L-Glutamate dehydrogenase (G2626). NAD+ (N7004). L-Glutamate (G1626, G1251). (B) L-Glutamine (G3126). │ │---------------→. │. ↓ ... L-Glutamate dehydrogenase (G2626). Brain, liver, muscle and other tissues. Amonia-fixation and -generation. Olivoponto- ...https://www.sigmaaldrich.com/technical-documents/articles/biology/rbi-handbook/non-peptide-receptors-synthesis-and-metabolism/glutamate-gaba-synthesis-and-metabolism.html
Frontiers | A Comprehensive Review of the 1H-MRS Metabolite Spectrum in Autism Spectrum Disorder | Frontiers in Molecular...
Succinate-Semialdehyde Dehydrogenase. ... The succinic semialdehyde is oxidized to re-enter the Krebs ... Succinate is also taken up by available α-ketoglutarate to reform glutamate (Bak et al., 2006; Rae, 2014). ... Lactate is synthesized via the enzyme lactate dehydrogenase from pyruvate, which is synthesized from glucose from the capillary ... GABA transaminase metabolizes GABA and α-ketoglutarate to form succinic semialdehyde. ...https://www.frontiersin.org/articles/10.3389/fnmol.2016.00014/full
pcd - Piperideine-6-carboxylate dehydrogenase - Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) - pcd gene ...
Cluster: Succinate-semialdehyde dehydrogenase [NADP+]. 4. Full view. Protein. Similar proteins. Organisms. Length. Cluster ID. ... Piperideine-6-carboxylate dehydrogenaseImported. ,p>Information which has been imported from another database using automatic ... Belongs to the aldehyde dehydrogenase family.UniRule annotation. ,p>Information which has been generated by the UniProtKB ... tr,Q4KJ45,Q4KJ45_PSEF5 Piperideine-6-carboxylate dehydrogenase OS=Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 ...http://www.uniprot.org/uniprot/Q4KJ45
Phenelzine - DrugBank
Succinate-semialdehyde dehydrogenase binding. Specific Function. Catalyzes the conversion of gamma-aminobutyrate and L-beta- ... aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate ...https://www.drugbank.ca/drugs/DB00780
Pyruvic acid - DrugBank
Succinate-semialdehyde dehydrogenase binding. Specific Function. Catalyzes the conversion of gamma-aminobutyrate and L-beta- ... aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate ... 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency. Disease. Pharmacogenomic Effects/ADRs Not Available. ... Pyruvate dehydrogenase activity. Specific Function. The pyruvate dehydrogenase complex catalyzes the overall conversion of ...https://www.drugbank.ca/drugs/DB00119
KEGG BRITE: KEGG Orthology (KO) - Mycobacterium tuberculosis Haarlem
TBHG_00234 succinate-semialdehyde dehydrogenase [NADP] dependent GabD1 TBHG_01688 succinate-semialdehyde dehydrogenase GabD2 ... succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:18.104.22.168 22.214.171.124 126.96.36.199] K00135 gabD; ... succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:188.8.131.52 184.108.40.206 220.127.116.11] K00265 gltB; ... TBHG_02416 NAD-dependent glutamate dehydrogenase Gdh TBHG_01170 pyrroline-5-carboxylate dehydrogenase RocA TBHG_01833 glutamine ...http://www.genome.jp/kegg-bin/get_htext?mtul00001+TBHG_00332
Application # 2004/0137586. Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids ...
1. succinyl CoA-CoA transferase; 2. succinate semialdehyde dehydrogenase; 3. 4-hydroxybutyrate dehydrogenase; 4. 4- ... succinate-semialdehyde dehydrogenase (sucD) and 4-hydroxybutyrate dehydrogenase (4hbD) have been identified (Sohling and ... Succinate semialdehyde dehydrogenases are encoded by gabD and sad. These activities could be deleterious for the purpose of ... glutamate-succinic semialdehyde transaminase, glutamate dehydrogenase, glutamate decarboxylase, 4-hydroxybutyrate dehydrogenase ...http://patents.com/us-20040137586.html
KEGG BRITE: Enzymes - Fragaria vesca (woodland strawberry)
18.104.22.168 lactaldehyde dehydrogenase 22.214.171.124 2-oxoaldehyde dehydrogenase (NAD+) 126.96.36.199 succinate-semialdehyde dehydrogenase ( ... 188.8.131.52 aldehyde dehydrogenase (NAD+) 101298221 aldehyde dehydrogenase family 2 member B4 101311183 aldehyde dehydrogenase ... 101298824 aldehyde dehydrogenase family 7 member A1 K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:184.108.40.206] K00128 ALDH; ... 101311533 aldehyde dehydrogenase family 3 member H1-like 101313059 aldehyde dehydrogenase family 3 member H1-like 101310892 ...http://www.genome.jp/kegg-bin/get_htext?fve01000+101313059
Study Evaluating the Long-Term Safety of Desvenlafaxine Succinate Sustained-Release (DVS SR) in Subjects With Pain Associated...
Succinate-semialdehyde Dehydrogenase. An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by ... catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD+ as a coenzyme. Deficiency of this enzyme, causes 4- ... Succinate-coa Ligases. Enzymes that catalyze the first step leading to the oxidation of succinic acid by the reversible ... Desvenlafaxine Succinate. A cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a SEROTONIN AND ...https://www.bioportfolio.com/resources/trial/68898/Study-Evaluating-the-Long-Term-Safety-of-Desvenlafaxine-Succinate-Sustained-Release-DVS.html
Aldh7a1 MGI Mouse Gene Detail - MGI:108186 - aldehyde dehydrogenase family 7, member A1
PR:000033043 succinate semialdehyde dehydrogenase [NAD(P)+] Sad. (term hierarchy). * EC. 220.127.116.11, 18.104.22.168, 22.214.171.124 ...http://www.informatics.jax.org/marker/MGI:108186
Investigating genome reduction of Bordetella pertussis using a multiplex PCR-based reverse line blot assay (mPCR/RLB) | BMC...
Genes of known function include a putative succinate-demialdehyde dehydrogenase and a citrate utilization protein. ...https://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0500-7-727
ALDH5A1 Gene - GeneCards | SSDH Protein | SSDH Antibody
Aldehyde Dehydrogenase 5 Family Member A1, including: function, proteins, disorders, pathways, orthologs, and expression. ... succinate-semialdehyde dehydrogenase (NAD+) activity. TAS. --. GO:0009013. succinate-semialdehyde dehydrogenase [NAD(P)+] ... Succinate semialdehyde + NAD(+) + H(2)O = succinate + NADH. *SSDH_HUMAN,P51649. UniProtKB/Swiss-Prot EnzymeRegulation: Redox- ... Succinic semialdehyde dehydrogenase deficiency (SSADHD) [MIM:271980]. 24,515,204(+). ATACA(A/G)TGTTA. reference, missense. ...http://www.genecards.org/cgi-bin/carddisp.pl?gene=ALDH5A1
Complete genome sequence and metabolic potential of the quinaldine-degrading bacterium Arthrobacter sp. Rue61a | BMC Genomics |...
... which in a transamination reaction is converted to succinic semialdehyde. Oxidation by succinate semialdehyde dehydrogenase ... The genome of Arthrobacter strain Rue61a contains several genes of putative alcohol dehydrogenases and aldehyde dehydrogenases/ ... Moreover, there are a number of gene products that could be either oxidases or dehydrogenases, such as xanthine oxidase/ ... Whereas the glycerol-3-phosphate dehydrogenase GlpD is an NAD-independent flavoenzyme that passes electrons to the respiratory ...https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-13-534