Mesenchymal Stem/Stromal Cells Derived From Pluripotent Stem Cells", Mesenchymal Stromal Cells as Tumor Stromal Modulators, ... Stromal cells play a large role in the distinction of hematopoietic cells (cells that can differentiate into other blood cells ... Stromal cells, or mesenchymal stromal cells, are differentiating cells found in abundance within bone marrow but can also be ... tumor cells can convert these reactive stromal cells further and transition them into tumor-associated stromal cells (TASCs). ...
Significantly, there are additional non-epithelial stromal cells (NES) that exist alongside TEC within thymic microenvironments ... Significantly, there are additional non-epithelial stromal cells (NES) that exist alongside TEC within thymic microenvironments ... However, experimental evidence suggests these cells are important for thymus function by either directly influencing T-cell ... However, experimental evidence suggests these cells are important for thymus function by either directly influencing T-cell ...
Stromal cell supernatants. In some experiments, supernatants from the M2-10B4 stromal cell line or from Tfm stromal cell ... so that the B cells were not in direct contact with the stromal cell layer. M2-10B4 stromal cells are known to produce B cell ... Direct cell-cell contact between stromal cells and B cell precursors was not required for the androgenic effects. When bone ... When bone marrow cells were cocultured directly on a stromal cell support layer of M2-10B4 cells, suppressive effects of DHT (1 ...
... level by the inability of HESCs to morphologically transform from a stromal fibroblastoid cell to an epithelioid decidual cell ... level by the inability of HESCs to morphologically transform from a stromal fibroblastoid cell to an epithelioid decidual cell ... cell proliferation/motility, and programmed cell death. These results were confirmed by the demonstration that SRC-3 is ... We show here that, like SRC-2, SRC-3 is expressed in the epithelial and stromal cellular compartments of the human endometrium ...
... theca cells, Sertoli cells, Leydig cells, and fibroblasts of stromal origin, singly or in various combinations. According to ... the WHO, sex cord-stromal tumors are classified into the following categories: Granulosa-stromal cell tumors Granulosa cell ... Definition Sex cord-stromal tumors are groups of tumors composed of granulosa cells, ... Sex cord-stromal tumors are groups of tumors composed of granulosa cells, theca cells, Sertoli cells, Leydig cells, and ...
While multipotent mesenchymal stromal cells have been recently isolated from adult lung (L-MSCs), there is very limited data on ... While multipotent mesenchymal stromal cells have been recently isolated from adult lung (L-MSCs), there is very limited data on ... Lung-derived mesenchymal stromal cell post-transplantation survival, persistence, paracrine expression, and repair of elastase- ... Stem Cells Dev. 2011 Oct;20(10):1779-92. doi: 10.1089/scd.2011.0105. Epub 2011 Jul 6. ...
Mesenchymal Stromal Cells and Tissue-Specific Progenitor Cells: Their Role in Tissue Homeostasis. Stem Cells Int 2016;2016:1-11 ... In vitro cell culture and animal studies have demonstrated that mesenchymal stromal cells (MSCs) have the capacity to modify ... Mesenchymal stromal cells (MSCs) are cells of non-haematopoietic origin, with the capacity to differentiate into multiple ... Strategies to improve the therapeutic effects of mesenchymal stromal cells in respiratory diseases. Stem Cell Res Ther 2018;9: ...
Exosomes secreted by the umbilical cord mesenchymal stromal cells (UMSCs) and circular RNAs (circRNAs) derived from exosomes ... The upregulation of hsa_circ_0046060 decreased the intracellular glucose content in L-02 cells (43.45 vs. 16.87 pM/mg, ,span ... The mesenchymal stromal cell (MSC) is a class of adult stem cell family. They were initially identified in the bone marrow but ... Cell Culture and Establishment of Insulin Resistance Cell Model. The human liver cell line L-02 was cultured in 10% FBS- ...
Primordial germ cells and gastrointestinal stromal tumors respond distinctly to a cKit overactivating allele.. Return to Grants ... These results demonstrate a cell-context-dependent response to the cKit(V558Δ) mutation. We propose that AKT overload ... These results demonstrate a cell-context-dependent response to the cKit(V558Delta) mutation. We propose that AKT overload ... A constitutively activating mutation, cKit(V558Δ), causes gain-of-function phenotypes in mast cells and intestines, and ...
Compared with follicular epithelial cells, there are a few morphological studies on the stroma of human thyroid gland. In order ... Interfollicular fibroblasts in the human thyroid gland: recognition of a CD34 positive stromal cell network communicated by gap ... Interfollicular stromal fibroblasts also stained with CD34. The main constituent of the human thyroid stromal tissue was a CD34 ... plasma cells, macrophages, and mast cells. At the ultrastructural level, gap junctions between the cytoplasmic processes of ...
Mesenchymal stem/stromal cells (MSC) are the ideal source to study fat formation as they are the progenitors of adipocytes. In ... Simultaneous analysis of metabolites, lipids, and proteins in cell culture is challenging due to the compounds chemical ... 105 cells). We developed an innovative analytical workflow including standardization with in-house produced 13C isotopically ... The molecular study of fat cell development in the human body is essential for our understanding of obesity and related ...
The differentiation of endometrial stromal cells into decidual cells, termed decidualization, is an integral step in the ... Primary human endometrial stromal cells (HESCs) were subjected to small interfering RNA knockdown of WNK1 followed by in vitro ... WNK lysine deficient protein kinase 1 regulates human endometrial stromal cell decidualization, proliferation, and migration in ... "WNK lysine deficient protein kinase 1 regulates human endometrial stromal cell decidualization, proliferation, and migration in ...
Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer ... 2006). Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer ... Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer. ... Hedgehog ligands were expressed at higher levels in some cancer epithelial cell lines compared to noncancerous epithelial cells ...
However, our study showed that primary cultured cells represented endometriosis cells more clearly than cell lines. ... The estrogen-regulated lncRNA H19/miR-216a-5p axis alters stromal cell invasion and migration via ACTA2 in endometriosis.. ... The estrogen-regulated lncRNA H19/miR-216a-5p axis alters stromal cell invasion and migration via ACTA2 in endometriosis. ... The estrogen-regulated lncRNA H19/miR-216a-5p axis alters stromal cell invasion and migration via ACTA2 in endometriosis. ...
Expression of BDNF in bone marrow stromal cells Rat bone marrow stromal cells expressed BDNF as determined by RT-PCR (Figure 2A ... Expression of GDNF in bone marrow stromal cells Rat bone marrow stromal cells failed to express GDNF at passage 2, as assessed ... Bone marrow stromal cells (BMSC) are multipotent stem cells and are considered good candidates for cell restoration in injured ... Glial cell line-derived neurotrophic factor in bone marrow stromal cells of rat. Neuroreport 2005;16:581-4. 30. Gregory C, ...
High Expression of Stromal Cell-Derived Factor 1 (SDF-1) and NF-κB Predicts Poor Prognosis in Cervical Cancer Zhiwang Song ...
Australasian College of Sports Physicians-position statement: the place of mesenchymal stem/stromal cell therapies in sport and ... Australasian College of Sports Physicians-position statement: the place of mesenchymal stem/stromal cell therapies in sport and ...
Computationally-Guided Development of a Stromal Inflammation Histologic Biomarker in Lung Squamous Cell Carcinoma ... Computationally-Guided Development of a Stromal Inflammation Histologic Biomarker in Lung Squamous Cell Carcinoma. Scientific ... Based on this, we developed an H&E stromal inflammation (SI) score. The prognostic value of the SI score was validated by two ... Based on this, we developed an H&E stromal inflammation (SI) score. The prognostic value of the SI score was validated by two ...
8 more authors) (2018) Bone Marrow-Harvesting Technique Influences Functional Heterogeneity of Mesenchymal Stem/Stromal Cells ... Bone Marrow-Harvesting Technique Influences Functional Heterogeneity of Mesenchymal Stem/Stromal Cells and Cartilage ... But the cartilage regeneration capacity of these cells remains unpredictable because of cell heterogeneity. Hypothesis: The ... The harvest technique of BM may be of major importance in determining the clinical success of BM mesenchymal stem/stromal cells ...
Culture of cell line. Human gist cell line (GIST-882 cell) was purchased from cosmobio company in Japan. The cells were ... Cell proliferation experiment. Cell morphology observation and cell counting method: the cells in the logarithmic growth period ... Plate cell clonogenesis experiment. The GIST-882 cell lines of different intervention groups were made into cell suspension and ... Transwell migration and invasion experiment: 5 × 104 gist cells (200ul cell suspension) in each Transwell cell chamber (with or ...
T cells and either CHO or CHO-FAP cells. T cells cocultured with CHO-FAP cells showed strong CD25 induction and target cell ... and T-cell, B-cell, and NK-cell function. While T-cell- and NK-cell-attractant chemokines (CXCL9, CXCL10, CXCL11) were also ... EnAd-SA-FAP-BiTE does not induce T-cell activation or FAP+ cell lysis in the absence of tumor cells. A, Cytotoxicity in T-cell ... EnAd-SA-FAP-BiTE does not induce T-cell activation or FAP+ cell lysis in the absence of tumor cells. A, Cytotoxicity in T-cell ...
Mesenchymal stromal cells (MSCs) show great promise for a wide range of applications including treating graft-vs-host disease, ... Nanofabulous Seminar: micro and nanotechnologies to direct mesenchymal stromal cell fate for tissue regeneration. ... Nanofabulous Seminar: micro and nanotechnologies to direct mesenchymal stromal cell fate for tissue regeneration - Melbourne ... ARC Training Centre for Cell and Tissue Engineering Technologies,. Monash University 11:00am, 16/03/2023. At the Melbourne ...
CD34+ Corneal Stromal Cells are Haemopoietic Stem Cells You will receive an email whenever this article is corrected, updated, ... M. Sosnova, M. Bradl, J.V. Forrester; CD34+ Corneal Stromal Cells are Haemopoietic Stem Cells . Invest. Ophthalmol. Vis. Sci. ... In addition, CD34+ cells were CD11c-, CD11b+. Less then 10% of the CD34+ cells also co-expressed Sca-1+, but no CD34+ cells co- ... After short term culture of corneal stromal explants nonadherent cells were harvested, cytospins prepared and stained for ...
In PC3 cells, cells expressing CD44 and CD133 were found and showed stem cell properties [11]. In DU145 cells, cells expressing ... Stromal cells from PZ or TZ of human prostates had similar proliferation rate in mice. CFSE-labeled stromal cells mixed with ... Cell Stem Cell. 2011May6;8(5):486-98 5. Chen W, Wang GM, Liu YJ. Cancer stem-like cells in human prostate carcinoma cells DU145 ... which suggests that the isolated cells were pure stromal cells.. The isolated stromal cells were further stained with anti- ...
Mesenchymal stromal cells are essential components of hematopoietic stem and progenitor cell (HSPC) niches, regulating HSPC ... Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis. Authors: ... We have now found that this ventral domain is the sclerotome, and that two markers of mammalian mesenchymal stem/stromal cells ... In zebrafish, we previously found that the stromal cells of the caudal hematopoietic tissue (CHT), a niche functionally ...
Protein kinase G activation of KATP channels in human-cultured prostatic stromal cells. In: Cellular Signalling. 2002 ; Vol. 14 ... Protein kinase G activation of KATP channels in human-cultured prostatic stromal cells. / Cook, Anna-Louise; Frydenberg, Mark; ... Protein kinase G activation of KATP channels in human-cultured prostatic stromal cells. Cellular Signalling. 2002;14(12):1023 ... title = "Protein kinase G activation of KATP channels in human-cultured prostatic stromal cells", ...
Deletion of Pkd1 in renal stromal cells causes defects in the renal stromal compartment and progressive cystogenesis in the ... Deletion of Pkd1 in renal stromal cells causes defects in the renal stromal compartment and progressive cystogenesis in the ... Deletion of Pkd1 in renal stromal cells causes defects in the renal stromal compartment and progressive cystogenesis in the ... 2017-9-11). "Deletion of Pkd1 in renal stromal cells causes defects in the renal stromal compartment and progressive ...
input.ds, character string specifying name of input GCT file containing stromal, immune, and estimate scores for each sample ... I want to calculate immune scores and stromal scores by employing the ESTIMATE algorithm, then analyze the relationship of ... immune/stromal scores with subtype classification and cytogenetic risk by one-way analysis of variance, but I dont know how to ...