Cyclic mechanical stretch promotes energy metabolism in osteoblast-like cells through an mTOR signaling-associated mechanism
Studies have demonstrated the role mechanical stress plays in regulating osteoblastic functions, such as cellular proliferation ... such as fluid shear stress (9-11) and hydrostatic pressure (12,13). Studies have also shown that mechanical stimuli regulate ... The expression of Fn14 via mechanical stress-activated JNK contributes to apoptosis induction in osteoblasts. J Biol Chem. 289: ... the following points also imply the close correlation of mechanical stress, mTOR signals and energy metabolism: i) tensile ...https://spandidos-publications.com/ijmm/36/4/947
Cytosolic Alkalinization of Vascular Endothelial Cells Produced by an Abrupt Reduction in Fluid Shear Stress | Circulation...
Mechanical stress mechanisms and the cell: an endothelial paradigm. Circ Res. 1993;72:239-245. ... Fluid shear stress was then abruptly reduced by rapidly decreasing flow from 1.6 to 0.2 mL/min. Shear stress was calculated by ... Cells were exposed to 20 mmol/L NH4Cl in bicarbonate buffer for 4 minutes at a fluid shear stress of 2.7 dyne/cm2. Shear stress ... After the 30-minute period at a shear stress of 2.7 dyne/cm2, shear stress was abruptly decreased to 0.3 dyne/cm2. After the ...http://circres.ahajournals.org/content/82/7/803
Experimental Methodology Using Digital Image Correlation to Assess Ballistic Helmet Blunt Trauma | Journal of Applied Mechanics...
Copyright © 2011 by American Society of Mechanical Engineers Topics: Deformation , Wounds , Exergy , Experimental methods , ... Copyright in the material you requested is held by the American Society of Mechanical Engineers (unless otherwise noted). This ... Mechanical Engineer Army Research Laboratory, System Engineering & Experimentation Branch, Aberdeen Proving Ground, MD 21005 ... Mechanical Engineer Army Research Laboratory, System Engineering & Experimentation Branch, Aberdeen Proving Ground, MD 21005 ...http://appliedmechanics.asmedigitalcollection.asme.org/article.aspx?articleid=1476946
Cyclic hardening in copper described in terms of combined monotonic and cyclic stress-strain curves (Journal Article) | SciTech...
of the Witwatersrand, Johannesburg (South Africa). School of Mechanical Engineering). Publication Date:. 1995-01-01. OSTI ... On stress reversal, a characteristic cyclic stress-strain curve is followed until the stress reaches a value in reverse loading ... Steady state cyclic behavior is reached when a stress associated with the monotonic stress-strain curve is reached which is ... 36 MATERIALS SCIENCE; COPPER; HARDENING; DISLOCATIONS; FLOW STRESS; MATHEMATICAL MODELS; METALLURGICAL EFFECTS; MICROSTRUCTURE ...https://www.osti.gov/scitech/biblio/6549453
Patient is on ALS patient on mechanical ventilator settings A/c 10, vt 650, It 1.5, ABG 7.47 pc02 25, po2 89, HCO3 18
... - ... Traffic on JustAnswer rose 14 percent...and had nearly 400,000 page views in 30 days...inquiries related to stress, high blood ... Patient is on ALS patient on mechanical ventilator settings A/c 10, vt 650, It 1.5, ABG 7.47 pc02 25, po2 89, HCO3 18 (Chronic ...https://www.justanswer.com/medical/2v1n8-patient-als-patient-mechanical-ventilator-settings.html
Elastic Constants of Single Crystal Hastelloy X at Elevated Temperatures | Journal of Engineering Materials and Technology |...
Topics: Temperature , Crystals , Elastic constants , Nickel , Alloys , Acoustics , Stress , Mechanical properties , Aerospace ... Department of Mechanical and Audio Engineering Technology, The University of Hartford, 200 Bloomfield Ave., West Hartford, CT ... The increased accuracy of the acoustically determined constants resulted in up to a 15 percent change in the predicted stresses ... Copyright in the material you requested is held by the American Society of Mechanical Engineers (unless otherwise noted). This ...http://materialstechnology.asmedigitalcollection.asme.org/article.aspx?articleid=1425774
Damage models for UHPFRC and R-UHPFRC tensile fatigue behaviour
Considering that stress transfer from UHPFRC to steel rebars is characteristic of the R-UHPFRC tensile fatigue behaviour and is ... Mechanical Engineering. *Materials Science and Engineering. *Microengineering. *Bioengineering. * Computer and Communication ... caused by fatigue damaging of the UHPFRC part, evolution of the modulus of deformation, i.e. the ratio of stress to strain of ...https://infoscience.epfl.ch/record/208151
Mechanical stress modulates bone remodeling signals | SpringerLink
Mechanical stress plays an essential role in bone homeostasis. Although mechanotransduction-induced de novo gene expression is ... mechanical stress JNK/p38 MAP kinase bone remodeling Fn14 MCP-3 This is a preview of subscription content, log in to check ... Mechanical stress plays an essential role in bone homeostasis. Although mechanotransduction-induced de novo gene expression is ... 2010) Mechanical stress modulates bone remodeling signals. In: Sasano T., Suzuki O. (eds) Interface Oral Health Science 2009. ...https://link.springer.com/chapter/10.1007%2F978-4-431-99644-6_21
Mechanical stress is communicated between... & related info | Mendeley
Tissue remodeling often reflects alterations in local mechanical conditions and manifests as an integrated response among the ... We show that (i) mechanical stress can be communicated from stressed to unstressed cells to elicit a remodeling response, and ( ... might communicate a mechanical stress by using airway cells as a representative in vitro system. Normal stress is imposed on ... Mechanical stress is communicated between different cell types to elicit matrix remodeling.. *Swartz M ...https://www.mendeley.com/research-papers/mechanical-stress-communicated-between-different-cell-types-elicit-matrix-remodeling/
When mechanical stress alters developmental gene expression
When mechanical pressure is applied to the embryo, ß catenin enters the cell nucleus (on right), whereas to perform its role as ... But on applying mechanical pressure to the Drosophila embryo, Emmanuel Farge noted that the Twist gene was then expressed in ... Significantly, the Twist gene is not expressed in mutant embryos in which this mechanical pressure is absent. This is the first ... "Mechanical Induction of Twist in the Drosophila Foregut/Stomodeal Primordium" Emmanuel Farge Current biology (www.current- ...https://www.innovations-report.com/html/reports/life-sciences/report-21487.html
How cells protect themselves against mechanical stress | EurekAlert! Science News
The voltage sensitivity appears to be an ancient property of these channels that protects cells from mechanical stress. ... The Piezo1 and Piezo2 ion channels are known to open up response to the slightest mechanical stimulus. MDC researchers have now ... The mechanism seems to protect blood cells from the mechanical stress they would otherwise be permanently exposed to as they ... How cells protect themselves against mechanical stress Max Delbrück Center for Molecular Medicine in the Helmholtz Association ...https://www.eurekalert.org/pub_releases/2018-03/mdcf-hcp031518.php
Fat Cells and Their Response to Mechanical Stress
How fat cells respond to mechanical loads can be studied now through a new method developed by researchers at the Tel Aviv ... Stress and the Gender Divide. Stress has become entwined in the current lifestyle of a young working couple and has resulted in ... Gefen, applying mechanical loads on tissues can affect many different cells within our bodies. He believes that, much like bone ... Gefen and his team of researchers can determine how much mechanical load can be tolerated by fat cells, and at what point the ...http://www.medindia.net/news/Fat-Cells-and-Their-Response-to-Mechanical-Stress-77169-1.htm
Endogenous patterns of mechanical stress are required for branching morphogenesis. - PubMed - NCBI
Arrows denote regions of high mechanical stress that branch, and asterisks denote regions of high mechanical stress that do not ... Mechanical stress profiles of tubules surrounded by matrices of different stiffness: (A) Ematrix = 680 Pa, (B) Ematrix = 860 Pa ... Mechanical stress profiles of tubules with increasing contractility: prestress (pt) that yields prestrain (ε0) of (A) 0.2 % (B) ... Endogenous patterns of mechanical stress are required for branching morphogenesis.. Gjorevski N1, Nelson CM. ...https://www.ncbi.nlm.nih.gov/pubmed/20717570?dopt=Abstract
Analysis on thermo-mechanical stress of thermoelectric module - IEEE Conference Publication
A heat cycle test was performed in order to analyze the thermo-mechanical ... This paper describes the thermo-mechanical performance of thermoelectric modules. ...http://ieeexplore.ieee.org/document/843396/?reload=true&arnumber=843396&contentType=Conference+Publications
Abstract 10698: Syndecan-4 Regulates Myofibroblast Differentiation Following Mechanical Stress | Circulation
Abstract 10698: Syndecan-4 Regulates Myofibroblast Differentiation Following Mechanical Stress. Kate M Herum, Ida G Lunde, Dina ... Mechanical stress caused by pressure overload of the heart leads to differentiation of cardiac fibroblasts into myofibroblasts ... Abstract 10698: Syndecan-4 Regulates Myofibroblast Differentiation Following Mechanical Stress. Kate M Herum, Ida G Lunde, Dina ... Abstract 10698: Syndecan-4 Regulates Myofibroblast Differentiation Following Mechanical Stress. Kate M Herum, Ida G Lunde, Dina ...http://circ.ahajournals.org/content/124/Suppl_21/A10698
Cells | Free Full-Text | Under Pressure: Mechanical Stress Management in the Nucleus
Here, we review recent advances demonstrating that mechanical stress emanating from the cytoskeleton can activate pathways in ... Cells are constantly adjusting to the mechanical properties of their surroundings, operating a complex mechanochemical feedback ... mechanical stress mechanotransduction; nucleoskeleton; lamina; lamin; LINC; nucleus; mechanical stress ... Belaadi, N.; Aureille, J.; Guilluy, C. Under Pressure: Mechanical Stress Management in the Nucleus. Cells 2016, 5, 27. ...http://www.mdpi.com/2073-4409/5/2/27
NIOSHTIC-2 Publications Search - 00181265 - Back injuries: mechanical stresses in the human spine.
The finite element models of lumbar motion segments were useful in analyzing internal stresses, given segment geometry, ...https://www.cdc.gov/niosh/nioshtic-2/00181265.html
Mechanical Stress Downregulates MHC Class I Expression on Human Cancer Cell Membrane
The cancer and healthy cell populations were treated either with mechanical stress delivered by a micropump (fabricated by deep ... PCA analysis was also performed to distinguish control and stressed cells within different cell lines. These mechanical induced ... Moreover, Raman spectroscopy analysis, after mechanical treatment, in the range between 700-1800 cm−1, indicated a relative ... In this work, we employed two different strategies to mechanically stress cancer cells. ...https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111758
Bone Strength and In-Flight Mechanical Stresses.
It was concluded that: (a) The ceramics used possessed adequate mechanical strength for use as femur sections in rhesus monkeys ... MECHANICAL PROPERTIES, STRESSES, CHEMICAL PROPERTIES, CRYSTALLOGRAPHY, BONES, LEGS ... It was concluded that: (a) The ceramics used possessed adequate mechanical strength for use as femur sections in rhesus monkeys ...http://oai.dtic.mil/oai/oai?verb=getRecord&metadataPrefix=html&identifier=AD0754982
Electrothermal mechanical stress reference design flow for printed circuit boards - The Engineer The Engineer
Electrothermal mechanical stress reference design flow for printed circuit boards. 4th December 2017 4:41 pm 4th December 2017 ... Electrothermal mechanical stress reference design flow for printed circuit boards. Contact Supplier ... This paper presents a reference design flow for solving the electrical, thermal and mechanical challenges of a printed circuit ... thermal and mechanical characteristics of the board - all using ANSYS tools. The multiphysics simulation yields power losses ...https://www.theengineer.co.uk/supplier-network/product/electrothermal-mechanical-stress-reference-design-flow-printed-circuit-boards/
Influence of photo-initiator concentration on residual mechanical stress in SU-8 thin films
... experimental results on the residual mechanical stress generated during the different steps of the photolithography process of ... The main aim is to investigate the causes and optimise the fabrication process in order to minimise the residual stresses. It ... Therefore, it is important to investigate each process step in relation to the internal stress formulation during the SU-8 ... during the fabrication process considerable internal stress is generated in SU-8 films, which causes the appearance of cracked ...http://www.nsti.org/procs/Nanotech2006v1/1/W60.611
Effects of dynamic mechanical stresses on mammalian cell metabolism
The cells were stressed at 0, 450 and 900 dynes/cm$\sp2$ at 37$\sp\circ$C for 5 min. Damage caused by the stresses was ... The effects of dynamic mechanical stresses on the arachidonic acid (AA) metabolism of human platelets and on the cell growth ... The cells were stressed by suspending them in laminar simple shear flows. Washed human platelet suspensions were stressed at 75 ... the results are in contrast to the accepted view that mechanical stresses developed in the circulation directly cause the ...https://scholarship.rice.edu/handle/1911/16477
Radial vs Axial Turbine, diff in mechanical stress | Physics Forums - The Fusion of Science and Community
Similar Discussions: Radial vs Axial Turbine, diff in mechanical stress * Centripetal vs radial? (Replies: 13) ... I have conducted a couple of experiments to demonstrate that there is less mechanical stress in the radial approach as compared ... someone out there please explain the basic math principles that show why an axial turbine will have more mechanical stresses ...https://www.physicsforums.com/threads/radial-vs-axial-turbine-diff-in-mechanical-stress.674726/
RecA Homology Search is Promoted by Mechanical Stress Along the Scanned Duplex DNA
... DSpace/Manakin Repository. * DASH Home ... RecA homology search is promoted by mechanical stress along the scanned duplex DNA. Nucleic Acids Research 40, no. 4: 1717-1727 ... RecA Homology Search is Promoted by Mechanical Stress Along the Scanned Duplex DNA. ... RecA Homology Search is Promoted by Mechanical Stress Along the Scanned Duplex DNA. ...https://dash.harvard.edu/handle/1/11210457
Mechanical Stress Effects on the Cardiovascular Adaptations of Peripheral Arterial Calcifications Among Athletes - Full Text...
Mechanical Stress Effects on the Cardiovascular Adaptations of Peripheral Arterial Calcifications Among Athletes (MediaSport). ... Impact and Consequences of Mechanical Stress on the Cardiovascular Adaptations of Peripheral Arterial Calcifications. ...https://clinicaltrials.gov/show/NCT01577576