CREB-binding protein, DAX1 LMNA, and TWIST2. BHLHE40 BHLHE41 Sterol regulatory element-binding protein GRCh38: Ensembl release ... Ericsson J, Edwards PA (Jul 1998). "CBP is required for sterol-regulated and sterol regulatory element-binding protein- ... DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1)". The Journal of ... Wang X, Briggs MR, Hua X, Yokoyama C, Goldstein JL, Brown MS (Jul 1993). "Nuclear protein that binds sterol regulatory element ...
... the transcription factor sterol-regulatory element binding protein 1c (SREBP-1c) and the enzymes diacylglycerol acyltransferase ... Dimitrios Iliopoulos 1 , Konstantinos Drosatos, Yaeko Hiyama, Ira J Goldberg, Vassilis I Zannis ... 1 Department of Biological Chemistry and Molecular Pharmacology, School of Medicine, Harvard University, Boston, MA, USA. ... DGAT2), fatty acid synthase (FAS), and acyl-CoA carboxylase 1 (ACC1) that regulate fatty acid and triglyceride biosynthesis. ...
Overexpression of SREBP1 (sterol regulatory element binding protein 1) promotes de novo fatty acid synthesis and ... Overexpression of SREBP1 (sterol regulatory element binding protein 1) promotes de novo fatty acid synthesis and ... Overexpression of SREBP1 (sterol regulatory element binding protein 1) promotes de novo fatty acid synthesis and ...
Sterol regulatory element binding protein 1 (SREBP1; gene name SREBF1) is known to be the master regulator of lipid homeostasis ... Overexpression of SREBP1 (sterol regulatory element binding protein 1) promotes de novo fatty acid synthesis and ... Overexpression of SREBP1 (sterol regulatory element binding protein 1) promotes de novo fatty acid synthesis and ... Overexpression of SREBP1 (sterol regulatory element binding protein 1) promotes de novo fatty acid synthesis and ...
1] was the first who studied the role of heredity in acne. Neonatal, nodulocystic, and conglobate acne have proven genetic ... Sterol regulatory element binding protein. 5αR-I:. 5 Alpha reductase type 1 ... C-peptide, insulin-like growth factors I and II, insulin-like growth factor binding protein-1 in cord serum of twins: genetic ... Insulin-like growth factors, insulin-like growth factor binding proteins and ovarian androgen production. Horm Res. 1994;42:49- ...
MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HLD in vivo ... MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice ... sterol regulatory element binding protein (SREBP) 1 (2A4, Santa Cruz), SREBP-2 (Cayman), TF2B (EP4588, Abcam), or β-actin (C4, ... 33 located within the intron of sterol regulatory element binding protein (SREBP) 2 controls cholesterol homeostasis and can be ...
SREBF1 protein, human * Sterol Regulatory Element Binding Protein 1 * Transcription Factors * Epidermal Growth Factor ... 1 Department of Dermatology, University of California, San Francisco, USA. [email protected] ... Various cytokine/growth factor signaling pathways are abnormal in aged skin, particularly in the interleukin-1 family. Barrier ...
... which downregulates low density lipoprotein receptor-related protein-1, a key Aβ clearance receptor. Hypoxia stimulated SRF/ ... generates an Aβ non-clearing VSMC phenotype through transactivation of sterol regulatory element binding protein-2, ... Sterol regulatory element binding proteins downregulate LDL receptor-related protein (LRP1) expression and LRP1-mediated ... Sterol regulatory element-binding protein-2 negatively regulates low density lipoprotein receptor-related protein transcription ...
By contrast, addition of free fatty acids (FFA, oleic acid/palmitic acid 2:1) caused aggravation of LPS-induced inflammatory ... By contrast, addition of free fatty acids (FFA, oleic acid/palmitic acid 2:1) caused aggravation of LPS-induced inflammatory ... over a time period of 1 and 5 days. Pro-inflammatory TNFα and pro-fibrotic TGFβ released into the supernatants were measured by ... Endotoxin regulates the maturation of sterol regulatory element binding protein-1 through the induction of cytokines. Eur. ...
Isolate epithelial cells from freshly dissociated mouse epithelial tissues by negative selection in under 1 hour. This product ... Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism. R. Bertolio et al. Nature ... Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regulate lipid biosynthesis and ... Mechanistically, we show that activation of AMP-activated protein kinase (AMPK) by ECM stiffening and geranylgeranylated RhoA- ...
Disturbed flow activates sterol regulatory element-binding protein- (SREBP-) mediated gene expression and hence leads to ... On the other hand, replacing animal proteins by plant proteins significantly reduced CV mortality. In the same line, the ... that bind to oxLDL allowing the uptake of these proteins into the cell [46]. Macrophages express enzymes such as acyl coenzyme ... or Yes-associated protein (YAP), and transcriptional coactivator with PDZ-binding motif (TAZ) are suppressed by unidirectional ...
Sterol regulatory element binding protein (SREBP)-1 is a transcription factor with important roles in the control of fatty acid ... sterol regulatory element binding protein-cleavage-activating protein; SREBP; sterol regulatory element binding protein; UCSD, ... Sterol regulatory elements binding proteins (SREBPs) (1-3) are a key transcription factor family that play an important role in ... Sterol regulatory element binding protein (SREBP)-1 is a transcription factor with important roles in the control of fatty acid ...
T. Horie, T. Nishino, O. Baba et al., "MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice," ... The combined use of ultrasound and DNA-bound bubbles has been found to improve DNA transfection both in vitro and in vivo ... It can also be used as an artificial blood substitute with the development of tetraphenylporphyrinato-iron (II) bound to ... PFC particles can infiltrate into arterial walls after balloon injury, cross the internal elastic lamina, and bind and localize ...
... whereas SREBP1 and cAMP response element binding protein (CREB) regulate adipose tissue differentiation and metabolism by ... Recent studies have found that PNS or monomer notoginsenosides have regulatory effects on obesity and lipid metabolism in ... and CCAAT/enhancer binding protein (C/EBP) are considered to be key early regulators of adipogenesis (Wu et al., 1999; Rosen et ... Hardie, D. G. (2011). AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. Genes Dev. 25 ...
Neuronal Activity-Induced Sterol Regulatory Element Binding Protein-1 (SREBP1) is Disrupted in Dysbindin-Null Mice-Potential ... Maturation and activity of sterol regulatory element binding protein 1 is inhibited by acyl-CoA binding domain containing 3. ... Tran LM, Bang SH, Yoon J, Kim YH, Min J. Effect of GTP-binding protein (YPT1 protein) on the enhanced yeast vacuolar activity. ... Striatum specific protein, Rhes regulates AKT pathway. Neuroscience Letters. 521: 142-7. PMID 22683505 DOI: 10.1016/j.neulet. ...
Expression of sterol regulatory element binding protein 1 (SREBP-1), ATP-citrate lyase (ACL), fatty acid synthase (FAS), malic ... Hepatic expression of fatty acid binding protein (FABP), very low density apolipoprotein II (ApoVLDL-II) and apolipoprotein B ( ... Therefore, it is important to understand the genetic regulatory mechanisms for controlling fat metabolism in poultry during ... Publication Date: 3/1/2003 Citation: Richards, M.P., Poch, S.M., Coon, C.N., Rosebrough, R.W., Ashwell, C.M., McMurtry, J.P. ...
... accumulate different lipid classes and downregulate sterol regulatory elementbinding protein 1. The FEBS Journal, vol. 273, no ... accumulate different lipid classes and downregulate sterol regulatory elementbinding protein 1. The FEBS Journal, vol. 273, no ... accumulate different lipid classes and downregulate sterol regulatory elementbinding protein 1. The FEBS Journal, vol. 273, no ... studied the TP53 gene and its protein product in SW480 cells, and their results suggested that TP53 with mutations R273H and ...
T2 - Sterol regulatory element binding proteins (SREBPs): Controllers of lipid synthesis and cellular uptake ... title = "Seventeenth Marabou Symposium on Diet and Genetic Interactions: Sterol regulatory element binding proteins (SREBPs): ... Seventeenth Marabou Symposium on Diet and Genetic Interactions: Sterol regulatory element binding proteins (SREBPs): ... Seventeenth Marabou Symposium on Diet and Genetic Interactions: Sterol regulatory element binding proteins (SREBPs): ...
... genes required for de novo lipogenesis are all regulated by the transcription factor sterol regulatory element-binding protein- ... cAMP response element-binding protein) was used as an invariant control protein for nuclear protein immunoblots and was ... Carbohydrate responsive element-binding protein (ChREBP): a key regulator of glucose metabolism and fat storage. Biochem ... and carbohydrate response element-binding protein (ChREBP), which is activated by glucose (9, 10). Blocking the lipogenic ...
... sterol regulatory element-binding protein 1-c (SREBP1-c), in the liver and adipose tissue. CPP suppressed the expression of ... fatty acid binding protein 4 (Fabp4) and Mgat1 genes; more interestingly, CGA treatment also attenuated inflammation in the ... which is involved in correct protein folding, and protein deglycase (DJ-1), which regulates autophagy [11]. In an elegant study ... Coffee enhances the expression of chaperones and antioxidant proteins in rats with nonalcoholic fatty liver disease. Transl. ...
Sterol Regulatory Element Binding Protein (Srebp) and Fatty Acid Synthase (Fas)) and reduced expression of hepatic beta- ... Aluvihare, V.R.; Kallikourdis, M.; Betz, A.G. Regulatory T cells mediate maternal tolerance to the fetus. Nat. Immunol. 2004, 5 ... In mice, a low-protein diet led to a global sperm DNA hypomethylation, which was not associated with a reduced fertility but ... Watkins, A.J.; Sinclair, K.D. Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice. ...
Sesamin has been shown to decrease the gene expression of sterol regulatory element binding protein-1 (SREBP-1), acetyl-CoA ... decreases fatty acid synthesis in rat liver accompanying the down-regulation of sterol regulatory element binding protein-1. ... These different isoforms vary in their affinity to ligands, distribution throughout the body, and cofactors proteins they bind ... The PPAR/RXR dimer then binds to a peroxisome proliferators-response element (Staels and Fruchart 2005), a DNA-specific ...
Spatial distribution and function of sterol regulatory element-binding protein 1a and 2 homo- and heterodimers by in vivo two- ... Dive into the research topics of Spatial distribution and function of sterol regulatory element-binding protein 1a and 2 homo ... Sterol Regulatory Element Binding Protein 2 100% * Sterol Regulatory Element Binding Protein 1 85% ...
Vitamin D may also act as an inhibitor of sterol regulatory element-binding proteins activation, thus controlling lipid ... fatigue and an increase in c-reactive protein, discrete leukopenia, a decrease in total complement levels and positive anti-DNA ... In this review [1], the physical and psychosocial consequences of cancers and cancer treatment on the sexual life of male and ... 1) analyzed a sample of 2,683 postmenopausal women from the Womens Health Initiative (WHI) cohort, with normal body mass index ...
A fusion protein containing C-terminal amino acids 833-1141 of human SREBP-2, was used as immunogen. The antibody recognizes ... A fusion protein containing C-terminal amino acids 833-1141 of human SREBP-2, was used as immunogen. The antibody recognizes ... Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection. J ... Cleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosis. EMBO J. 1996; 15(5):1012-1020. ( ...
Sterol regulatory element binding protein 1 (SREBP1) antibody Product code : pab50192 Raised in : Rabbit Clonality : Polyclonal ... Neuronal PAS domain-containing protein 4 (NPAS4) antibody Product code : pab0482 Raised in : Rabbit Clonality : Polyclonal ... Neuronal PAS domain-containing protein 4 (NPAS4) antibody Product code : pab0482-P ... Hypoxia inducible factor-1 alpha antibody (H1alpha67) Product code : mab50046 Raised in : Mouse Clonality : Monoclonal antibody ...
LDL receptors and decrease the expression of sterol regulatory element binding protein 1 and CAAT element binding protein-α in ... lower TGF-β messenger RNA and protein levels, and lower connective tissue growth factor messenger RNA and protein content in ... For example, in a variety of tissues in diabetic animals, fenugreek dosing led to a drop in lipid peroxide and protein carbonyl ... Fenugreek seeds are composed of 20% to 30% protein, 45% to 60% carbohydrates (mainly the galactomannan, mucilaginous fibers in ...
... that encodes a putative metalloprotease required for intramembrane proteolysis of sterol-regulatory element-binding proteins ( ... Mutation of the putative zinc-binding residues abolishes S2P activity. S2P encodes an unusual metalloprotease that cleaves ... S2P defines a new family of polytopic membrane proteins that contain an HEXXH sequence characteristic of zinc metalloproteases ... wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary ...
... receptor α and adenosine monophosphate activated protein kinase with stimulation of sterol regulatory element binding protein 1 ... receptor α and adenosine monophosphate activated protein kinase with stimulation of sterol regulatory element binding protein 1 ... sterol regulatory element-binding proteins), which enhance cholesterol and triglyceride biosynthesis and fibrosis via stellate ... Ji C, Chan C, Kaplowitz N. Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic ...