HSD17B1 | Cancer Genetics Web
... no increases in the transcripts of transporters or steroid hydroxylases or CYP19A1 were observed. This delayed increase in the ... RT-qPCR data reveal that 17β-HSD1 increases the mRNA levels of estrogen receptors (ER) alpha and beta by 171 and 120%, ... steroid biosynthetic process - steroid metabolic process Data from Gene Ontology via CGAP [Hide] ... Steroid sulfatase inhibition success and limitation in breast cancer clinical assays: An underlying mechanism.. J Steroid ...
PIN1 | Cancer Genetics Web
... we found an enriched representation of bacterial gene pathways involved in steroid biosynthesis and steroid hormone ... Collagen prolyl 4-hydroxylase 1 is essential for HIF-1α stabilization and TNBC chemoresistance.. Nat Commun. 2018; 9(1):4456 [ ... RESULTS: Twelve transcription factors were identified as having potential significance in lung cancer (CREB1, NUCKS1, HOXB4, ... By modulating alpha ketoglutarate (α-KG) and succinate levels P4HA1 expression reduces proline hydroxylation on hypoxia- ...