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*  Fatty Acid Desaturase Gene Polymorphisms and Metabolic Measures in Schizophrenia and Bipolar Patients Taking Antipsychotics
... relationship with stearoyl-CoA desaturase activity," Schizophrenia Research, vol. 129, no. 1, pp. 66-73, 2011. View at ... Furthermore, it has been determined that D5D is encoded by the fatty acid desaturase 1 (FADS1) gene and D6D is encoded by the ... The two desaturases have an opposite effect on the risk of developing diabetes. Specifically, an increased D5D activity is ... D. M. Merino and D. W. Ma, "Genetic variation in lipid desaturases and its impact on the development of human disease," Lipids ...
https://www.hindawi.com/journals/cpn/2013/596945/
*  Validation of SteatoNet.a) Simulation of fasting condit | Open-i
Simulation of stearoyl CoA desaturase (SCD) knockout. The lipogenic diet was simulated until time ... pcbi-1003993-g004: Validation of SteatoNet.a) Simulation of fasting condition, b) Simulation of stearoyl CoA desaturase (SCD) ... pcbi-1003993-g004: Validation of SteatoNet.a) Simulation of fasting condition, b) Simulation of stearoyl CoA desaturase (SCD) ... Serum fatty acids (FAB), phosphoenolpyruvate carboxykinase (PEPCK), acetyl CoA carboxylase 1 (ACC1), fatty acid synthase (FAS ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4263370_pcbi.1003993.g004&req=4
*  Association of Stearoyl-coA desaturase 1 Activity with Familial Combined Hyperlipidemia
Leptin and the control of metabolism: role for stearoyl-CoA desaturase-1 (SCD-1) J Nutr. 2004;134:2455S-2463S. [PubMed] ... Stearoyl-coA desaturase 1 (SCD1) is the rate-limiting enzyme involved in the synthesis of monounsaturated fatty acids, and in ... Association of Stearoyl-coA desaturase 1 Activity with Familial Combined Hyperlipidemia. Rebecca Mar-Heyming, Makoto Miyazaki, ... 2. Ntambi JM, Miyazaki M. Recent insights into stearoyl-CoA desaturase-1. Curr Opin Lipidol. 2003;14:255-261. [PubMed] ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2758768/?lang=en-ca
*  GSK 1940029 - AdisInsight
... a stearoyl CoA desaturase 1 inhibitor, as a topical gel for the treatment of acne vulgaris. Phase I clinical ... Mechanism of Action Stearoyl CoA desaturase inhibitors * Orphan Drug Status Orphan designation is assigned by a regulatory body ...
http://adisinsight.springer.com/drugs/800038814?error=cookies_not_supported&code=f0caea24-800a-42fe-a77e-04a77f380f36
*  NSC 14613 | CAS 91396-88-2 | AbMole BioScience | NSC 14613 Price
NSC 14613 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs. Buy ... MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat ... NSC 14613 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs. ...
http://www.abmole.com/products/nsc-14613.html
*  The regulation of hepatic stearoyl-coenzyme A desaturase in obese-hyperglycaemic (ob/ob) mice by food intake and the fatty acid...
1. The effects of food intake and the fatty acid composition of the diet on the hepatic stearoyl-CoA desaturase activity of ... The regulation of hepatic stearoyl-coenzyme A desaturase in obese-hyperglycaemic (ob/ob) mice by food intake and the fatty acid ... 6. Limiting the food intake of obese mice by pair-feeding with lean mice decreased their acyl-CoA desaturase activity when the ... The regulation of hepatic stearoyl-coenzyme A desaturase in obese-hyperglycaemic (ob/ob) mice by food intake and the fatty acid ...
http://www.biochemj.org/content/206/3/561
*  Fatty acid composition of tissue cultured breast carcinoma: effect of stearoyl-CoA desaturase-1 (SCD-1) inhibitor | OncologyPRO
63P - Fatty acid composition of tissue cultured breast carcinoma: effect of stearoyl-CoA desaturase-1 (SCD-1) inhibitor. ... Stearoyl-CoA desaturase 1 (SCD1) has been introduced as a novel therapeutic target in malignancies, including breast cancer. ... Fatty acid composition of tissue cultured breast carcinoma: effect of stearoyl-CoA desaturase-1 (SCD-1) inhibitor ...
http://oncologypro.esmo.org/Topics/Breast-Cancer/Fatty-acid-composition-of-tissue-cultured-breast-carcinoma-effect-of-stearoyl-CoA-desaturase-1-SCD-1-inhibitor
*  Gentaur Molecular :Biovis \ SCD1 Inhibitor \ 1716-5
... desaturase 1) (Delta-9 desaturase 1) (Fatty acid desaturase 1) (Stearoyl-CoA desaturase 1). [Scd1 Scd] Acyl-CoA desaturase 1 ( ... Acyl-CoA desaturase 1 (EC 1.14.19.1) (Delta(9)-desaturase 1) (Delta-9 desaturase 1) (Fatty acid desaturase 1) (Stearoyl-CoA ... SCD1] Stearoyl-CoA desaturase-1 (EC 1.14.19.1). [SCD1] Stearoyl-CoA desaturase (EC 1.14.19.1). [NR1D2] Nuclear receptor ... EC 1.14.19.1) (Delta(9)-desaturase 1) (Delta-9 desaturase 1) (Fatty acid desaturase 1) (Stearoyl-CoA desaturase 1). [Scd1 mCG_ ...
http://www.antibody-antibodies.com/product_det.php?id=1772552&supplier=search&name=SCD1%20Inhibitor
*  Scd4 - Acyl-CoA desaturase 4 - Mus musculus (Mouse) - Scd4 gene & protein
... insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA ... and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes ... Fatty acid desaturase 4Curated. Stearoyl-CoA desaturase 41 Publication. ,p>Manually curated information that is based on ... stearoyl-CoA 9-desaturase activity Source: MGI ,p>Inferred from Direct Assay,/p> ,p>Used to indicate a direct assay for the ...
http://www.uniprot.org/uniprot/Q6T707
*  Cancer Cell Dependence on Unsaturated Fatty Acids Implicates Stearoyl-CoA Desaturase as a Target for Cancer Therapy | Molecular...
Inhibition of stearoyl-CoA desaturase 1 expression induces CHOP-dependent cell death in human cancer cells. PLoS One 2010;5: ... Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver. J Biol Chem 1992;267:10925-30. ... Inhibition of stearoyl-CoA desaturase 1 expression in human lung adenocarcinoma cells impairs tumorigenesis. Int J Oncol 2008; ... Development of a novel LC/MS method to quantitate cellular stearoyl-CoA desaturase activity. Anal Chim Acta 2008;627:99-104. ...
http://mcr.aacrjournals.org/content/9/11/1551.full
*  Abstract 192: Targeting stearoyl CoA desaturase 1 (SCD1) in hepatobilliary carcinoma | Cancer Research
Abstract 192: Targeting stearoyl CoA desaturase 1 (SCD1) in hepatobilliary carcinoma. John Alton Copland, Laura A. Marlow, Ilah ... Abstract 192: Targeting stearoyl CoA desaturase 1 (SCD1) in hepatobilliary carcinoma. John Alton Copland, Laura A. Marlow, Ilah ... Abstract 192: Targeting stearoyl CoA desaturase 1 (SCD1) in hepatobilliary carcinoma. John Alton Copland, Laura A. Marlow, Ilah ... Abstract 192: Targeting stearoyl CoA desaturase 1 (SCD1) in hepatobilliary carcinoma Message Subject (Your Name) has forwarded ...
http://cancerres.aacrjournals.org/content/77/13_Supplement/192
*  The Evolutionary Pattern and the Regulation of Stearoyl-CoA Desaturase Genes
... Xiaoyun Wu,1,2 Xiaoju Zou,3 Qing Chang,2 Yuru ... Stearoyl-CoA desaturase (SCD) is a key enzyme that converts saturated fatty acids (SFAs) to monounsaturated fatty acids (MUFAs ...
https://www.hindawi.com/journals/bmri/2013/856521/abs/
*  Regulation of stearoyl-CoA desaturases and role in metabolism. - PubMed - NCBI
Regulation of stearoyl-CoA desaturases and role in metabolism.. Ntambi JM1, Miyazaki M. ... Stearoyl-CoA desaturase (SCD) is the rate-limiting enzyme catalyzing the synthesis of monounsaturated fatty acids, mainly ...
https://www.ncbi.nlm.nih.gov/pubmed/14654089?access_num=14654089&link_type=MED&dopt=Abstract
*  Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors. | Sigma-Aldrich
Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors.. [Zhili Xin, Hongyu Zhao, Michael D Serby, Bo Liu ... A series of structurally novel stearoyl-CoA desaturase1 (SCD1) inhibitors has been identified via molecular scaffold ...
https://www.sigmaaldrich.com/catalog/papers/18632269
*  Stearoyl-CoA desaturase-1 - Wikipedia
Stearoyl-CoA desaturase-1 is a key enzyme in fatty acid metabolism. It is responsible for forming a double bond in Stearoyl-CoA ... Stearoyl-CoA desaturase (Δ-9-desaturase) is an endoplasmic reticulum enzyme that catalyzes the rate-limiting step in the ... "Entrez Gene: Stearoyl-CoA desaturase (delta-9-desaturase)". Retrieved 2011-09-29. Paton, Chad M.; Ntambi, James M. (2017-03-08 ... Stearoyl-CoA desaturase (SCD; EC 1.14.19.1) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis ...
https://en.wikipedia.org/wiki/Stearoyl-CoA_desaturase-1
*  Holdings: Stearoyl-CoA desaturase genes in lipid metabolism /
Stearoyl-CoA desaturase genes in lipid metabolism / Obesity and diabetes develop as a complex result of genetic, metabolic and ... Stearoyl-CoA desaturase (SCD) genes are a critical regulator of lipogenesis and catalyzes the synthesis of monounsat... ...
https://library.villanova.edu/Find/Record/1468717
*  Abstract 4772: Stearoyl-CoA Desaturase (SCD1) regulates liver tumor initiating cells through modulating ER stress | Cancer...
Abstract 4772: Stearoyl-CoA Desaturase (SCD1) regulates liver tumor initiating cells through modulating ER stress. Kin Fai Ma, ... Stearoyl-CoA Desaturase (SCD1) regulates liver tumor initiating cells through modulating ER stress [abstract]. In: Proceedings ... Abstract 4772: Stearoyl-CoA Desaturase (SCD1) regulates liver tumor initiating cells through modulating ER stress ... Abstract 4772: Stearoyl-CoA Desaturase (SCD1) regulates liver tumor initiating cells through modulating ER stress ...
http://cancerres.aacrjournals.org/content/77/13_Supplement/4772
*  Inhibition of hepatic stearoyl-CoA desaturase activity by trans-10, cis-12 conjugated linoleic acid and its derivatives.
... has been reported to decrease stearoyl-CoA desaturase (SCD) activity by decreasing mRNA expression. This investigation was ... Conjugated linoleic acid (CLA) has been reported to decrease stearoyl-CoA desaturase (SCD) activity by decreasing mRNA ... 10903479 - Inhibition of hepatic stearoyl-coa desaturase activity by trans-10, cis-12 conjugated l.... 17428609 - Flavonoids ... 0/Linoleic Acids; 506-32-1/Arachidonic Acid; EC 1.14.19.1/Stearoyl-CoA Desaturase ...
http://www.biomedsearch.com/nih/Inhibition-hepatic-stearoyl-CoA-desaturase/10903479.html
*  Acyl CoA Desaturase (Fatty Acid Desaturase or Delta 9 Desaturase or Stearoyl CoA Desaturase or SCD or EC 1.14.19.1) - Pipeline...
Fatty Acid Desaturase or Delta 9 Desaturase or Stearoyl CoA Desaturase or SCD or EC 1.14.19.1) - Pipeline Review, H1 2018 Acyl ... Acyl CoA Desaturase (Fatty Acid Desaturase or Delta 9 Desaturase or Stearoyl CoA Desaturase or SCD or EC 1.14.19.1) - Stearoyl- ... Acyl CoA Desaturase (Fatty Acid Desaturase or Delta 9 Desaturase or Stearoyl CoA Desaturase or SCD or EC 1.14.19.1) - Pipeline ... Acyl CoA Desaturase (Fatty Acid Desaturase or Delta 9 Desaturase or Stearoyl CoA Desaturase or SCD or EC 1.14.19.1) - Pipeline ...
https://www.marketresearch.com/Global-Markets-Direct-v3480/Acyl-CoA-Desaturase-Fatty-Acid-11692651/
*  Stearoyl-CoA desaturase 5
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the ... insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA ... Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into ... saturated fatty acyl-CoA substrates. Catalyzes the ... GWAS Trait for Stearoyl-CoA desaturase 5. Eosinophil percentage ...
https://pharos.nih.gov/idg/targets/Q86SK9
*  Download Stearoyl Coa Desaturase Genes In Lipid Metabolism 2013
... Download Stearoyl Coa Desaturase Genes In Lipid Metabolism ... The download Stearoyl CoA Desaturase Genes in Lipid of the important course( the possible largest knowledge and the necessary ... The download Stearoyl CoA Desaturase Genes in Lipid Metabolism can n't enable broken to Receive the SQL Plan Management ... Revised mailing download Stearoyl CoA Desaturase Genes on layers. destination widely-used studies speak detailed for the page ...
http://cloudcomputing365.net/wp-content/plugins/ebook/download-Stearoyl-CoA-Desaturase-Genes-in-Lipid-Metabolism-2013.html
*  Overexpression of stearoyl-CoA desaturase 1 in bone marrow mesenchymal stem cells enhance the expression of induced endothelial...
Stearoyl-CoA desaturase 1 (SCD1), which converts SFA to MUFA, is involved in the cellular biosynthesis of MUFAs from SFA ... Stearoyl-CoA desaturase 1 (SCD1), known as a ∆9 desaturase, is an integral membrane protein anchored in the endoplasmic ... The substrates of SCD1 are mainly stearoyl-CoA (C18:0) and palmitoyl-CoA (C16:0), which are desaturated to oleoyl-CoA (C18:1) ... Tao J, Shi J, Lu Y, Dou B, Zhou Z, Gao M, Zhu Z: Overexpression of stearoyl-CoA desaturase 1 in bone-marrow mesenchymal stem ...
https://lipidworld.biomedcentral.com/articles/10.1186/1476-511X-13-53
*  Stearoyl-CoA Desaturase 1-Targeted Therapy - 2012-062 - Mayo Clinic Ventures
Broad patent claims have issued claiming methods for treating renal cell carcinoma by using SCD1 inhibitors and are available for licensing. ...
http://technologies.ventures.mayoclinic.org/technologies/2012-062_stearoyl-coa-desaturase-1-targeted-therapy
*  The evolutionary history of the stearoyl-CoA desaturase gene family in vertebrates
... Castro, L.F.C., Wilson, J.M., Gonçalves, O ... The evolutionary history of the stearoyl-CoA desaturase gene family in vertebrates. ... Galante-Oliveira, S., Rocha, E., Cunha, I. The evolutionary history of the stearoyl-CoA desaturase gene family in vertebrates ( ... A novel Acetyl-CoA synthetase short-chain subfamily member 1 (Acss1) gene indicates a dynamic histor…. ...
http://castroevolab.com/index.php/publications/238-the-evolutionary-history-of-the-stearoyl-coa-desaturase-gene-family-in-vertebrates
*  Novel Stearoyl CoA Desaturase 1 (SCD1) Inhibitors - 2014-229 - Mayo Clinic Ventures
Novel Stearoyl CoA Desaturase 1 (SCD1) Inhibitors. Technology #2014-229. Questions about this technology? Ask a Technology ... Computer modeling followed by synthesis of novel compounds and testing for stearoyl CoA desaturase 1 (SCD1) specific growth ...
http://technologies.ventures.mayoclinic.org/technologies/2014-229_novel-stearoyl-coa-desaturase-1-scd1-inhibitors