Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting STAT3: the Role of STAT1 | Molecular Pharmacology  Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting STAT3: the Role of STAT1 | Molecular Pharmacology
Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting STAT3: the Role of STAT1. Vivian W. Y. Lui, Amanda L. ... Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting STAT3: the Role of STAT1. Vivian W. Y. Lui, Amanda L. ... Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting STAT3: the Role of STAT1. Vivian W. Y. Lui, Amanda L. ... Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting STAT3: the Role of STAT1 ...
more infohttp://molpharm.aspetjournals.org/content/early/2007/02/26/mol.106.032284.1
An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells |...  An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells |...
The transcription factor Bcl6 is required for development of follicular helper T (TFH) cells. Cytokines that activate Stat3 ... An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells. Hao ... An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells ... An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells ...
more infohttp://www.jimmunol.org/content/195/5/2080.abstract?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&andorexacttitle=and&andorexacttitleabs=and&fulltext=anaspec%20September&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&tdate=8/31/2016&resourcetype=HWCIT
Activation of Stat3 transcription factor by Herpesvirus saimiri STP-A oncoprotein. - Semantic Scholar  Activation of Stat3 transcription factor by Herpesvirus saimiri STP-A oncoprotein. - Semantic Scholar
Here we demonstrate that STP-A11 interacts with signal transducer and activator of transcription 3 (Stat3) independently of Src ... STP-A11 formed a triple complex with Src kinase and Stat3 where Src kinase phosphorylated Stat3, resulting in the nuclear ... These results demonstrate that STP-A11 independently targets two important cellular signaling molecules, Src and Stat3, and ... Consequently, the constitutively active Stat3 induced by STP-A11 elicited cellular signal transduction, which ultimately ...
more infohttps://www.semanticscholar.org/paper/Activation-of-Stat3-transcription-factor-by-saimiri-Chung-Cho/924f71ac8427c7cd16d40e37fb43393a8c33e119
Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+ Th Cells | The...  Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+ Th Cells | The...
Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+ Th Cells. Kaitlin A. ... Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+ Th Cells ... Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+ Th Cells ... Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+ Th Cells ...
more infohttp://www.jimmunol.org/content/early/2017/08/26/jimmunol.1700106
STAT3 Transcription Factor - Pharma Knowledge Base  STAT3 Transcription Factor - Pharma Knowledge Base
STAT3 Transcription Factor' h2_font_container='color:%23000000' h2_google_fonts='font_family:Merienda%3Aregular%2C700,font_ ... STAT3 Transcription Factor. A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN- ... STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130. ... STAT3 Transcription Factor. /Definitions /immunology /Terms /STAT3 Transcription Factor. * February 8, 2017. ...
more infohttp://www.pharmakb.com/term-stat3-transcription-factor/
STAT3 Transcription Factor | The Chopra Library  STAT3 Transcription Factor | The Chopra Library
... inducible activation of signal transducer and activator of transcription 3 (STAT3), which is an oncogenic transcription factor ... inducible activation of signal transducer and activator of transcription 3 (STAT3), which is an oncogenic transcription factor ... The epidermal growth factor receptor (EGFR)-signal transducer and activator of transcription (STAT)-3 signaling pathway is ... The epidermal growth factor receptor (EGFR)-signal transducer and activator of transcription (STAT)-3 signaling pathway is ...
more infohttp://isharonline.org/tags/stat3-transcription-factor
Research programme: STAT3 transcription factor inhibitors - Moleculin Biotech - AdisInsight  Research programme: STAT3 transcription factor inhibitors - Moleculin Biotech - AdisInsight
Mechanism of Action STAT3 transcription factor inhibitors * Orphan Drug Status Orphan designation is assigned by a regulatory ... Research programme: STAT3 transcription factor inhibitors - Moleculin Biotech Alternative Names: CABE; caffeic acid benzyl ...
more infohttp://adisinsight.springer.com/drugs/800037878?error=cookies_not_supported&code=b7267431-1c71-457a-bd4a-4c3948dd28a2
Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis. - Nuffield Department of...  Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis. - Nuffield Department of...
... an essential transcription factor with pleiotropic functions, plays critical roles in the pathogenesis of autoimmunity. Despite ... STAT3 was critical in modulating the balance of T helper 17 (Th17) and regulatory T (Treg) cells, as well as in promoting CD4 ... Using a T cell transfer model of colitis, we found that STAT3 expression in T cells was essential for the induction of both ... We found that STAT3 bound to multiple genes involved in Th17 cell differentiation, cell activation, proliferation, and survival ...
more infohttps://www.ndorms.ox.ac.uk/publications/58606
Degradation of the Transcription Factors NF-κB, STAT3, and STAT5 Is Involved in Entamoeba histolytica-Induced Cell Death in...  Degradation of the Transcription Factors NF-κB, STAT3, and STAT5 Is Involved in Entamoeba histolytica-Induced Cell Death in...
Degradation of the Transcription Factors NF-κB, STAT3, and STAT5 Is Involved in Entamoeba histolytica-Induced Cell Death in ... Degradation of the Transcription Factors NF-κB, STAT3, and STAT5 Is Involved in Entamoeba histolytica. -Induced Cell Death in ... Signal transducers and activators of transcription (STATs) comprise a family of transcription factors whose members are ... vascular endothelial growth factor, IL-10, and transforming growth factor [44,45,46,47,48]. In addition to STAT3 and STAT5, ...
more infohttp://parasitol.kr/journal/view.php?number=1812
Cancers | Free Full-Text | Cerebral Metastases from Malignant Melanoma: Current Treatment Strategies, Advances in Novel...  Cancers | Free Full-Text | Cerebral Metastases from Malignant Melanoma: Current Treatment Strategies, Advances in Novel...
STAT3 transcription factor cerebral metastasis; melanoma; surgery; radiotherapy; drug therapy; STAT3 transcription factor ...
more infohttp://www.mdpi.com/2072-6694/2/2/364
FOXO1A | Cancer Genetics Web  FOXO1A | Cancer Genetics Web
... or Krüppel-like zinc finger transcription factor 5 (KLF5). Ιn addition, E2 suppressed KLF5-mediated transcription through ERβ, ... FOXO transcription factors in cancer development and therapy.. Cell Mol Life Sci. 2016; 73(6):1159-72 [PubMed] Related ... This study demonstrates, for the first time, that loss of a single forkhead box class O (FoxO) transcription factor, can ... This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The ...
more infohttp://www.cancerindex.org/geneweb/FKHR.htm
Omega-3 polyunsaturated fatty acids promote liver regeneration after 90% hepatectomy in rats.  Omega-3 polyunsaturated fatty acids promote liver regeneration after 90% hepatectomy in rats.
0/Biological Markers; 0/Cytokines; 0/Fatty Acids, Omega-3; 0/Inflammation Mediators; 0/STAT3 Transcription Factor; 0/Stat3 ... In addition, activation of protein kinase B (Akt) and of signal transducer and activator of transcription 3 signaling pathway ... 4 and IL-10 levels were significantly increased whereas IL-6 and tumor necrosis factor-α levels were dramatically decreased. ...
more infohttp://www.biomedsearch.com/nih/Omega-3-polyunsaturated-fatty-acids/22783054.html
The serine/threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cells.  The serine/threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cells.
... cell survival through elaborating factors. We demonstrate herein that IL-6 and TNF family cytokines, TNFα, BAFF and APRIL, but ... 0/STAT3 Transcription Factor; 0/STAT3 protein, human; 0/myeloid cell leukemia sequence 1 protein; 154447-36-6/2-(4-morpholinyl ... STAT3 Transcription Factor / metabolism. Signal Transduction / drug effects, physiology. Sirolimus / pharmacology. Stromal ... BMSCs and OCs upregulate Pim-2 expression in MM cells largely via the IL-6/STAT3 and NF-κB pathway, respectively. Pim-2 short ...
more infohttp://www.biomedsearch.com/nih/kinase-Pim-2-novel-anti/21475253.html
KAKEN - Research Projects | Mechanisms for dendritic cell responses against host-derived molecules (KAKENHI-PLANNED-21117003)  KAKEN - Research Projects | Mechanisms for dendritic cell responses against host-derived molecules (KAKENHI-PLANNED-21117003)
Presentation] PDLIM2 regulates Th17-mediated responses through degradation of STAT3 transcription factor2010. *. Author(s). T. ... Presentation] The transcription factor IRF8 is required for basophil development.2013. *. Author(s). H. Sasaki, D. Kurotaki, N ... Presentation] The Ets transcription factor Spi-B is essential for M-cell differentiation.2012. *. Author(s). T. Kanaya ... Journal Article] Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells.2015. * ...
more infohttps://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-21117003/
The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against...  The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against...
Simultaneously, levels of the biologically active phospho-STAT3 were decreased and correlated with reduced transcription of the ... Subsequent effects on transcription of genes regulating the cell cycle were analyzed by quantitative real-time PCR. Effects on ... Levels of the transcription factor phospho-STAT3, a potential target of Curcumin, were determined by sandwich-ELISA. ... Curcumin reduces intracellular levels of the transcription factor STAT3, resulting in reduced transcription of cell cycle ...
more infohttps://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-10-491
Phospho anti-STAT3 (S727) antibody [E121-31] (ab32143) | Abcam  Phospho anti-STAT3 (S727) antibody [E121-31] (ab32143) | Abcam
Rabbit recombinant monoclonal STAT3 (phospho S727) antibody [E121-31] validated for WB, IHC, ICC/IF and tested in Human and Rat ... Signal transducer and activator of transcription 3 (acute phase response factor) antibody ... Dot Blot analysis of Lane 1: STAT3 (pS727) phospho peptide and Lane 2: STAT3 non-phospho peptide labeling STAT3 (phospho S727) ... Anti-STAT3 (phospho S727) antibody [E121-31]. See all STAT3 primary antibodies. ...
more infohttp://www.abcam.com/STAT3-phospho-S727-antibody-E121-31-ab32143.html
Johnson DE[au] - PubMed - NCBI  Johnson DE[au] - PubMed - NCBI
Biochemical Properties of a Decoy Oligodeoxynucleotide Inhibitor of STAT3 Transcription Factor.. Lee DS, O'Keefe RA, Ha PK, ... Frequent promoter hypermethylation of PTPRT increases STAT3 activation and sensitivity to STAT3 inhibition in head and neck ... STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma. ... STAT3 Cyclic Decoy Demonstrates Robust Antitumor Effects in Non-Small Cell Lung Cancer. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Johnson+DE%5Bau%5D&dispmax=50
David Heery - The University of Nottingham  David Heery - The University of Nottingham
Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a. Journal of Biological Chemistry. 277(10 ... I have a long-standing interest in transcription factors, and in particular the Nuclear Receptor family of ligand regulated TFs ... Nuclear Receptor Signaling; Transcription Factors & Coactivators. Histone Modifications; Chromatin Recognition, Oncogenic ... MOZ-TIF2 inhibits transcription by nuclear receptors and p53 by impairment of CBP function Molecular and Cellular Biology. 25(3 ...
more infohttps://www.nottingham.ac.uk/pharmacy/people/david.heery