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*  HBD fusions - Picard Lab home
... transcription factor transcription factor transcription factor transcription factor transcription factor as DNA binding factor ... c-Rel RUNX1 Snail Stat1, Stat5A, Stat5B Stat6 TLS-CHOP Twist Xbra Zinc finger TFs Zta ER e ER ER e GR ER e , PR ER e ... transcription factor transcription factor in fish transcription factor in yeast and plants transcription factor transcription ... transcription factor transcription factor transcription factor transcription factor MT-MC1 v-Myb c-Myc MyoD ER e ER ER, GR ER, ...
http://spotidoc.com/doc/695589/hbd-fusions---picard-lab-home
*  archive-com.com: cell-research.com - Cell Research
200031 China Correspondence Jianguo Song Tel 86 21 54921167 E mail jgsong sibs ac cn The forkhead box transcription factor A2 ... myoblast differentiation mainly by activating the JAK1 STAT1 STAT3 pathway OSM downregulated myocyte enhancer binding factor 2A ... 200433 China Correspondence Cheng He Tel 86 21 65515200 E mail chenghe smmu edu cn Glial cell line derived neurotrophic factor ... OSM receptor which constituted a positive feedback loop to further amplify OSM induced signaling Moreover we found that STAT1 ...
http://archive-com.com/com/c/cell-research.com/2016-02-14_7510755_81/Cell_Research/
*  STAT1 Transcription Factor - MeSH - NCBI
... and ProteinsProteinsTranscription FactorsSTAT Transcription FactorsSTAT1 Transcription Factor ... Signal TransducingSTAT Transcription FactorsSTAT1 Transcription Factor. All MeSH CategoriesChemicals and Drugs CategoryAmino ... Signal TransducingSTAT Transcription FactorsSTAT1 Transcription Factor. All MeSH CategoriesChemicals and Drugs CategoryAmino ... Signal TransducingSTAT Transcription FactorsSTAT1 Transcription Factor. All MeSH CategoriesChemicals and Drugs CategoryAmino ...
https://www.ncbi.nlm.nih.gov/mesh?Db=mesh&Cmd=DetailsSearch&Term=%22STAT1+Transcription+Factor%22%5BMeSH+Terms%5D
*  Nicotine, IFN-γ and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription...
... utilizing E2F1 and STAT1 transcription factors. Depletion of STAT1 or E2F1 abrogated the induction of MUC4; nicotine-mediated ... Chromatin immunoprecipitation assays and real-time PCR showed that transcription factors E2F1 and STAT1 can positively regulate ... IFN-γ and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and ... IFN-γ and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and ...
https://www.springermedizin.de/nicotine-ifn-%CE%B3-and-retinoic-acid-mediated-induction-of-muc4-in-p/9552080
*  Suppression of lipopolysaccharide-induced antiviral transcription factor (STAT-1 and NF-kappa B) complexes by antibody...
... studies showed that transcription factor IFN-alpha-activated factor (AAF), IFN-stimulated gene factor 3 (ISGF3), and nuclear ... The suppression of antiviral transcription factor complexes was shown to depend on replicating virus and was not simply a ... and IFN regulatory factor 1 (IRF-1), as well as for IFN-inducible protein 10 (IP-10) and IFN-beta; the transcription of a ... ablated or diminished message for tumor necrosis factor alpha (TNF-alpha), nitric-oxide synthase 2 (NOS2), ...
https://www.semanticscholar.org/paper/Suppression-of-lipopolysaccharide-induced-antiviral-Mahalingam-Lidbury/03ff79f01621588c38ca32818d8418413ee39866
*  Interferon-gamma signaling in human retinal pigment epithelial cells mediated by STAT1, ICSBP, and IRF-1 transcription factors....
Interferon-gamma signaling in human retinal pigment epithelial cells mediated by STAT1, ICSBP, and IRF-1 transcription factors ... Interferon-gamma signaling in human retinal pigment epithelial cells mediated by STAT1, ICSBP, and IRF-1 transcription factors ... RESULTS: HRPE cells constitutively expressed two members of the IFN regulatory factor (IRF) family of transcription factors, ... Interferon-gamma signaling in human retinal pigment epithelial cells mediated by STAT1, ICSBP, and IRF-1 transcription factors ...
https://iovs.arvojournals.org/article.aspx?articleid=2162065
*  Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting STAT3: the Role of STAT1 | Molecular Pharmacology
Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting STAT3: the Role of STAT1. Vivian W. Y. Lui, Amanda L. ... Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting STAT3: the Role of STAT1. Vivian W. Y. Lui, Amanda L. ... Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting STAT3: the Role of STAT1. Vivian W. Y. Lui, Amanda L. ... Antiproliferative Mechanisms of a Transcription Factor Decoy Targeting STAT3: the Role of STAT1 ...
http://molpharm.aspetjournals.org/content/early/2007/02/26/mol.106.032284.1
*  Publikationen - KNHI
Activation of STAT1 transcription factor precedes up-regulation of coxsackievirus - adenovirus receptor during viral ... Mitochondrial transcription factors TFA, TFB1 and TFB2: a search for DNA variants/haplotypes and the risk of cardiac ... Mutations in the cardiac transcription factor GATA4 in patients with lone atrial fibrillation. Eur J med Genet, 2010 ... Lack of association between insulin-like growth factor-1 or insulin-like growth factor-binding protein-3 and left ventricular ...
http://knhi.de/research/publications/
*  Chromosome 3p loss of heterozygosity is associated with a unique metabolic network in clear cell renal carcinoma | PNAS
S30). Notably, signal transducer and activator of transcription 1 (STAT1), an anticarcinogenic transcription factor (28), is ... targeting a certain transcription factor (reporter transcription factors). For each directionality class (up-, down-, or mixed ... In addition, a potential activation of STAT1 transcription factor was associated only with ccRCC. Such activation would trigger ... Apart from VHL loss-mediated stabilization of HIF, other transcription factors may be triggered only in ccRCC, thus shedding ...
https://www.pnas.org/content/111/9/E866
*  C/EBPδ overexpression decreases BIM expression and par | Open-i
... transcription factors. To this end, we presently evaluated the role of the transcription factor CCAAT/enhancer binding protein ... 10 and CCL20 in β-cells by hampering IRF-1 up-regulation and increasing STAT1 activation in response to cytokines. These ... transcription factors. To this end, we presently evaluated the role of the transcription factor CCAAT/enhancer binding protein ... The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells. ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3275575_pone.0031062.g007&req=4
*  ZFIN Publication: Song et al., 2011
STAT1 Transcription Factor/genetics; STAT1 Transcription Factor/metabolism*; Synteny/genetics; Zebrafish/embryology*; Zebrafish ... Stat1α, Stat1β, hematopoiesis, myeloid, granulocyte, zebrafish. MeSH Terms:. Animals; Biomarkers/metabolism; Cell Lineage; Gene ... Zebrafish stat1a encodes all five domains of the human STAT1-alpha splice form but, like the human STAT1-beta splice variant, ... To explore embryonic functions of STAT1, we investigated stat1b, an unstudied zebrafish co-ortholog of human STAT1. ...
https://zfin.org/ZDB-PUB-110920-26
*  A Nonconventional Nuclear Localization Signal within the UL84 Protein of Human Cytomegalovirus Mediates Nuclear Import via the...
Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha. EMBO J. 21:1754-1763. ... However, it has recently been reported that transcription factor STAT1 contains a nontransferable, lysine-rich NLS that is ... the cellular transcription factor Stat1 (47, 34, 35), the histone deacetylase 4 (18, 54), and the U1A spliceosome protein (22 ... Functional interaction between the human cytomegalovirus 86-kilodalton IE2 protein and the cellular transcription factor CREB. ...
https://jvi.asm.org/content/77/6/3734
*  Protein motion in the nucleus: from anomalous diffusion to weak interactions | Biochemical Society Transactions
2011) Activated STAT1 transcription factors conduct distinct saltatory movements in the cell nucleus. Biophys. J. 101, 2592- ... 2007) Probing transcription factor dynamics at the single-molecule level in a living cell. Science 316, 1191-1194 doi:10.1126/ ... 2017) DNA residence time is a regulatory factor of transcription repression. Nucleic Acids Res. 45, 11121-11130 doi:10.1093/nar ... transcription factor. Introduction. Mammalian gene expression and its regulation take place in the nucleus, a highly complex ...
http://www.biochemsoctrans.org/content/early/2018/07/29/BST20170310
*  Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue | SpringerLink
13). Moreover, ELK1, ETF and STAT1 transcription factor binding sites are significantly overrepresented in the inflammation ... Key transcription factors overrepresented in Clusters 1, 2 and 3 are HNF4, ELK1 and E2F, respectively (Fig. 5b; Suppl. Table 13 ... Table 11). The transcription factor Klf6 was among the strongest transcriptionally upregulated genes of this cluster. Klf6 is a ... Botella LM, Sanz-Rodriguez F, Komi Y et al (2009) TGF-beta regulates the expression of transcription factor KLF6 and its splice ...
https://link.springer.com/article/10.1007%2Fs00204-016-1761-4
*  Srikumar P. Chellappan | Moffitt
IFN-γ and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and ... GATA3 transcription factor abrogates Smad4 transcription factor-mediated fascin overexpression, invadopodium formation, and ... The E2F transcription factor is a cellular target for the RB protein. Cell. 1991 Jun;65(6):1053-1061. Pubmedid: 1828392. ... ChIP on Chip and ChIP-Seq Assays: Genome-Wide Analysis of Transcription Factor Binding and Histone Modifications. Methods Mol ...
https://moffitt.org/research-science/researchers/srikumar-chellappan/
*  Reduced surface expression of MHC class I antigens in d | Open-i
Reduced surface expression of MHC class I antigens in different subsets of STAT1−/− lymphocytes. Freshly isolated lymphocytes ... STAT1 Transcription Factor. *Transcription Factors/genetics. *Tumor Suppressor Proteins. Related in: MedlinePlus ... 2) suggested that STAT1 may be important even in the absence of IFN. To further examine the role of constitutive IFN signaling ... 2) suggested that STAT1 may be important even in the absence of IFN. To further examine the role of constitutive IFN signaling ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2195695_JEM990804.f4&req=4
*  Novel role and mechanisms of histone deacetylases in traumatic brain injury - Albert Einstein College of Medicine
5) HDAC3 inhibition reduces the activation of signal transducer and activator of transcription 1 (STAT1), a key molecule that ... Aim 2: Test if genetic knockout of the HDAC3-STAT1 signaling pathway shifts microglia/macrophages toward the beneficial and ... thereby regulating not only gene transcription but also the activity of various proteins through post-translational ...
https://einstein.pure.elsevier.com/en/projects/novel-role-and-mechanisms-of-histone-deacetylases-in-traumatic-br
*  Find Research Outputs - MD Anderson Cancer Center
STAT1 Transcription Factor Blood platelet function abnormalities in cirrhotic patients with esophageal varices in relation to ...
https://mdanderson.elsevierpure.com/en/publications/?format=&page=9
*  Graduate School of Medicine - Keio University
STAT1 Transcription Factor Medicine & Life Sciences Histamine Receptors Medicine & Life Sciences Cytokines Medicine & Life ...
https://keio.pure.elsevier.com/en/organisations/2061-graduate-school-of-medicine
*  Frontiers | Chromatin Landscape Distinguishes the Genomic Loci of Hundreds of Androgen-Receptor-Associated LincRNAs From the...
... that comprise chromatin regions with ARA-lincRNAs exhibit transcription factor contents, epigenetic marks and gene ... To find relevant epigenetic signatures enriched at the ARA-lincRNAs' transcription start sites (TSSs) we used a machine ... transcription factor. Androgen hormone binding to AR promotes its displacement from the cytoplasm to the nucleus and AR binding ... transcription factor. Androgen hormone binding to AR promotes its displacement from the cytoplasm to the nucleus and AR binding ...
https://www.frontiersin.org/articles/10.3389/fgene.2018.00132/full
*  A screening method for identifying disruptions in interferon signaling reveals HCV NS3/4a disrupts Stat-1 phosphorylation
STAT1 Transcription Factor (MeSH) * Viral Nonstructural Proteins (MeSH) * Viral Proteins (MeSH) * Virology (MeSH) ... NS3/4a was subsequently shown to inhibit phosphorylation of Stat-1 at the serine residue 727.the 2FTGH cell assay system can be ... We show that HCV NS3/4a is able to block this pathway at the stage of Stat-1 serine 727 phosphorylation. ... A screening method for identifying disruptions in interferon signaling reveals HCV NS3/4a disrupts Stat-1 phosphorylation ...
https://scholars.latrobe.edu.au/display/publication39775
*  Apoptotic, necrotic, or fused tumor cells: An equivalent source of antigen for dendritic cell loading
... the distinct modes of cancer cell death had analogous potential in activating the transcription factors NF-kappaB and STAT1 and ...
https://scholars.latrobe.edu.au/display/publication134069
*  HKU Scholars Hub: Regulation of XAF1 expression in human colon cancer cell by interferon β: Activation by the transcription...
STAT1 Transcription Factor - metabolism. en_HK. dc.subject.mesh. Signal Transduction - drug effects. en_HK. ... Regulation of XAF1 expression in human colon cancer cell by interferon β: Activation by the transcription regulator STAT1. en_ ... Regulation of XAF1 expression in human colon cancer cell by interferon β: Activation by the transcription regulator STAT1. ... IFNβ-induced XAF1 expression was mediated by Stat1 through the interaction with ISRE-XAF1. Knocking down of the Stat1 ...
http://hub.hku.hk/handle/10722/69059