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*  Presbycusis - Wikipedia
GPx1, an isoform of GPx, is predominantly expressed in stria vascularis, cochlea, spiral ligament, organ of Corti, and spiral ... The cochlea is tonotopically mapped in a spiral fashion, with lower frequencies localizing at the apex of the cochlea, and high ... Heredity: factors like early aging of the cochlea and susceptibility of the cochlea for drug insults are genetically determined ... Strial/metabolic: characterised by atrophy of stria vascularis in all turns of cochlea. Located in the lateral wall of the ...
https://en.wikipedia.org/wiki/Presbycusis
*  Spatiotemporal loss of K+ transport proteins in the developing cochlear lateral wall of guinea pigs with hereditary deafness -...
... between fibrocytes in the spiral ligament of the E50 gw/gw cochlea was observed. The barrier composed of tight junctions ... Michael C Kelly, Ping Chen, Development of form and function in the mammalian cochlea, Current Opinion in Neurobiology, 2009, ... Immunohistochemical analysis of the gw/gw cochlea showed loss of the tight junction protein CLDN11 in strial basal cells from ... RNAlater facilitates microdissection of sensory cell-enriched samples from the mouse cochlea for transcriptional analyses, ...
http://onlinelibrary.wiley.com/doi/10.1111/j.1460-9568.2007.05994.x/abstract?globalMessage=0
*  Spiral ligament fibrocyte-derived MCP-1/CCL2 contributes to inner ear inflammation secondary to nontypeable H. influenzae...
Previously, we showed that spiral ligament fibrocytes (SLFs) recognize OM pathogens and up-regulate chemokines. Here, we aim to ... After entering the cochlea from the middle ear through the round window membrane, bacterial molecules in the perilymph of the ... Cochlear resident macrophages are found to be localized in the spiral ligament and the spiral ganglion area [44], but further ... Immunolabeling shows MCP-1/CCL2 is highly expressed in the spiral ligaments (white arrows) and spiral limbus as well as the ...
https://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-10-314
*  Inner Ear Anatomy: Gross Anatomy, Embryology, Labyrinthitis
... the cochlea, which is dedicated to hearing, and (2) the vestibular system, which is dedicated to balance. The inner ear is ... The cochlea is a bony, spiral-shaped chamber that contains the cochlear duct of the membranous labyrinth. The sense of hearing ... The lateral wall of the cochlear duct is formed by the spiral ligament and the stria vascularis, which produces the endolymph. ... The walls of the bony labyrinth consist of dense bone everywhere except at 2 small areas near the base of the cochlear spiral. ...
https://emedicine.medscape.com/article/1968281-overview
*  Spiral ligament of cochlea | Define Spiral ligament of cochlea at Dictionary.com
Spiral ligament of cochlea definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation ... spiral ligament of cochlea. .css-7w6khc{padding-top:20px;}. .css-1oucjfz{list-style-type:none;line-height:22px;}. *spiral ... spiral ligament of cochlea. .css-xojh1k{position:relative;height:auto;overflow:hidden;padding-bottom:0px;margin-bottom:0px;}. . ...
https://www.dictionary.com/browse/spiral-ligament-of-cochlea
*  Frontiers | Cell volume regulation in epithelial physiology and cancer | Physiology
... big conductance potassium channel ameliorates cisplatin-induced apoptosis in spiral ligament fibrocytes of the cochlea. ... teraethylammonium or iberiotoxin similarly attenuates cisplatin-induced apoptosis in spiral ligament fibrocytes of the cochlea ...
https://www.frontiersin.org/articles/10.3389/fphys.2013.00233/full
*  Dural membrane | definition of dural membrane by Medical dictionary
The membrane extending from the tympanic lip of the osseous spiral lamina to the crest of the spiral ligament in the cochlea of ... The thin, jelly-like membrane projecting from the vestibular lip of the osseous spiral lamina and overlying the spiral organ of ... peridental membrane , periodontal membrane periodontal ligament.. placental membrane the membrane separating the fetal from the ... reticular membrane , reticulated membrane a netlike membrane over the spiral organ of the ear, through which pass the free ends ...
http://medical-dictionary.thefreedictionary.com/dural+membrane
*  Personensuche
Relation of the spiral ligament form to the auditory function. Cochlea-Forschung. ... Acoustic distortion products from the cochlea of the blind African mole rat, Cryptomys spec. ... The receptor and neuron distribution in the cochlea of the bat, Taphozous kachhensis. ... Acoustic distortion products from the cochlea of the African mole rat, Cryptomys hottentotus. ...
https://www.uni-due.de/zim/services/suchdienste/mitarbeiter.php?id=5704
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... and subsequent isolation of the cochlea, spiral ligament, and organ of Corti. Once isolated, the sensory epithelium can be ... the sensory epithelium for audition is located along the spiraling organ of Corti that resides within the conch shaped cochlea ... or as a further dissected micro-isolate that lacks the spiral limbus and spiral ganglion neurons. Using this method, primary ... The avian cochlea contains a population of resident macrophages, but the precise function of those cells is not known. The ...
https://www.jove.com/visualize/abstract/23240046/depletion-resident-macrophages-does-not-alter-sensory-regeneration
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... and subsequent isolation of the cochlea, spiral ligament, and organ of Corti. Once isolated, the sensory epithelium can be ... the sensory epithelium for audition is located along the spiraling organ of Corti that resides within the conch shaped cochlea ... or as a further dissected micro-isolate that lacks the spiral limbus and spiral ganglion neurons. Using this method, primary ... Neuroscience, Issue 36, hearing, mice, cochlea, organ of Corti, organotypic, culture, hair cell, stem cell, gene expression, in ...
https://www.jove.com/visualize/abstract/21479267/functional-changes-snail-statocyst-system-elicited
*  EAST syndrome - Wikipedia
... which is the upper portion of the fluid filled spiral ligament of the cochlea. The cochlea is the main region that translates ...
https://en.wikipedia.org/wiki/EAST_syndrome
*  Dopaminergic Signaling in the Cochlea: Receptor Expression Patterns and Deletion Phenotypes | Journal of Neuroscience
2001) Spiral ligament pathology: a major aspect of age-related cochlear degeneration in C57BL/6J mice. J Assoc Res Otolaryngol ... Special attention was paid to the basal-turn hair cells and to the type-IV fibrocytes in the spiral ligament, which are the ... D4 was detected in spiral ganglion cells only. In whole cochlea samples from adults, transcripts for D1, D2, D4, and D5 were ... spiral ligament and all supporting structures of the cochlear duct. For each case evaluated, serial sections through the entire ...
http://www.jneurosci.org/content/32/1/344.long
*  Distinct Expression Pattern of a Deafness Gene, KIAA1199, in a Primate Cochlea
Expression of KIAA1199 has been reported in the fibrocytes of the spiral ligament and the spiral limbus with a transient ... a and b) KIAA1199 expression is observed in the lateral wall of the cochlea, sensory epithelium, spiral limbus, and spiral ... LW: lateral wall of cochlea, OC: organ of Corti, SL: spiral limbus, SGN: spiral ganglion neuron, and RM: Reissner's membrane. ... Immunoreactivities for KIAA1199 were observed in the lateral wall spiral ligament, hair cells, supporting cells, spiral limbus ...
https://www.hindawi.com/journals/bmri/2016/1781894/
*  Trophic Support of Cultured Spiral Ganglion Neurons by Depolarization Exceeds and Is Additive with that by Neurotrophins or...
1987) Increased spiral ganglion cell survival in electrically stimulated deafened guinea pig cochleae. Laryngoscope 97:836-842. ... The bony cochlear capsule was removed, followed by the spiral ligament. The organ of Corti was then removed, transecting the ... 1995) Voltage dependent Ca2+ channels in the spiral ganglion cells of guinea pig cochlea. Hearing Res 91:196-201. ... Spiral ganglion neuronal survival as a function of [K+]o. Spiral ganglion cultures were prepared, maintained, and scored for ...
http://www.jneurosci.org/content/17/6/1959.long
*  Frontiers | Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere's Disease | Immunology
... the spiral ligament, and the reticular lamina in the neurosensory epithelium of the cochlea. ... A third hypothesis will involve the increase of NF-κB in fibrocytes within the spiral ligament and the spiral limbus after a ... Genetic mutations involving spiral ligament cells may lead to SNHL (61-63). Immune-mediated and acoustic trauma-mediated ... Fibrocytes of the Spiral Ligament, or/and the Tight Junctions (TJ) at the Reticular Lamina. This study provide evidences that ...
https://www.frontiersin.org/articles/10.3389/fimmu.2017.01739/full
*  Tectorial Membrane - Cochlea
Spiral Ganglion. *Spiral Ligament. *Spiral Organ (of Corti). *Tectorial Membrane. *Tunnel of Corti ... The membrane is joined to the bony shelf of the cochlea and passes like a roof over the receptor cells, making contact with the ...
https://www.innerbody.com/image_nerv14/nerv180.html
*  Cochlear Duct - Cochlea and Corti
Spiral Ganglion. *Spiral Ligament. *Spiral Organ (of Corti). *Tectorial Membrane. *Tunnel of Corti ... It lies between the two bony compartments and ends as a closed sac at the apex of the cochlea. ...
https://www.innerbody.com/image_nerv14/nerv178.html
*  Three-dimensional current flow in a large-scale model of the cochlea and the mechanism of amplification of sound | Journal of...
... cotransporter back into the type II fibrocytes of the spiral ligament and from there back via the stria vascularis into the ... The K+ circulation in the cochlea is thought to be tightly regulated in the inner compartment of the cochlea by a transport ... end of the cochlea (Mammano & Ashmore 1996; Preyer et al. 1996). In both mammalian and turtle cochleae, it is highly probable ... The cochlea also contains a specific population of hair cells, the outer hair cells (OHCs), which is thought to amplify the BM ...
http://rsif.royalsocietypublishing.org/content/6/32/279
*  Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV | (2011) | Publications | Spie
... the spiral ligament, the spiral limbus, and the modiolus could be clearly identified. When we imaged intact adult cochleae, we ... to image the vibration of various micro-structures of the cochlea at the same time. An excised cochlea of a guinea pig was ... Imaging of the intact mouse cochlea by spectral domain optical coherence tomography Author(s): Simon S. Gao; Tao Yuan; Anping ... The method has the potential to measure the response from a much wider region of the cochlea than any other currently used ...
http://spie.org/Publications/Proceedings/Volume/7889
*  The Protective Effect of Egb 761 Against 3-Nitropropionic Acid-Induced Hearing Loss: The Role of Sirtuin 1
Therefore, the second turn of the cochlea was used to count the cells. Type II fibrocytes in the spiral ligament and spiral ... Light microscopic images of the spiral ligament and type II fibrocyte counts in the second turn of the cochlea. Compared with ... Light microscopic images of the spiral ligament and type II fibrocyte counts in the second turn of the cochlea. Compared with ... The second turn of the cochlea was used to count immunoreactive cells. Immunoreactive cells were counted in the spiral ligament ...
https://www.e-ceo.org/journal/view.php?viewtype=pubreader&number=550
*  Head And Neck Session 6 Flashcards by Charlotte Manton | Brainscape
Delicate filaments (like arachnoid mater) and spiral ligament 35 Describe the structure of the cochlea. ... What does the cochlea have that is closed by the secondary tympanic membrane? ... Where is the spiral organ of Corti (receptor of auditory stimuli) located? ... Short limb is connected by a ligament to the posterior wall of the tympanic cavity ...
https://www.brainscape.com/flashcards/head-and-neck-session-6-5001524/packs/7172305
*  KAKEN - Research Projects | Immunohistochemical study for localization of G-protein and P-glycoprotein in the inner ear ...
Immunoreactivity in the spiral ligament was light. In the cochlear nerve and spiral ganglionic fibers, immunoreactivity against ... P-gp was found only in the capillary endothelial cells of the cochlea and vestibule. The pattern of P-gp immunostaining in the ... 1.Patterns of immunostaining in the guinea pig cochlea using anti-G-protein (Gsalpha, Gialpha, Goalpha) antibodies were ... lateral wall tissue of the cochlea, vestibular tissue and cochlear nerve in the modiolus. The present investigation suggested ...
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07671847/
*  Implanting a Therapeutic Appliance Into the Cochlea - Patent application
A stria vascularis 54 and spiral ligament 56 are juxtaposed with an inner surface of the promontory 32. FIG. 1 also illustrates ... to as the cochlea. The cochlea is a fluid-filled portion of the inner ear that contains nerve endings essential for hearing. [ ... Moreover, the spiral-shaped flutes on the polishing burr respectively of the initial fenestration burr and the sequence of ... 0002]The hearing portion of the inner ear is enclosed within a hollow, spiral otic capsule bone shaped like a snail shell that ...
http://www.patentsencyclopedia.com/app/20080215148
*  DiVA - Search result
... and its attachment to the spiral ligament (SL) (with a conceivable secondary spiral lamina [SSL] or secondary spiral plate) at ... Conclusions: Unlike in several mammalian species, the human SSL is restricted to the most basal portion of the cochlea around ... The secondary spiral lamina and its relevance in cochlear implant surgery2018In: Upsala Journal of Medical Sciences, ISSN 0300- ... primary and secondary osseous spiral laminae (OSL), and RWM using volume-rendering software. Confocal microscopy ...
http://uu.diva-portal.org/smash/resultList.jsf?af=%5B%5D&aq=%5B%5B%7B%22journalId%22%3A%228317%22%7D%5D%5D&aqe=%5B%5D&aq2=%5B%5B%5D%5D&language=en&query=