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*  Spindle apparatus - Wikipedia
Cells divide along the line connecting two centrosomes of the spindle apparatus. After formation, the spindle apparatus ... The cellular spindle apparatus includes the spindle microtubules, associated proteins, which include kinesin and dynein ... In cell biology, the spindle apparatus (or mitotic spindle) refers to the cytoskeletal structure of eukaryotic cells that forms ... The spindle apparatus is vaguely ellipsoid in cross section and tapers at the ends. In the wide middle portion, known as the ...
https://en.wikipedia.org/wiki/Spindle_apparatus
*  Stability of the small γ-tubulin complex requires HCA66, a protein of the centrosome and the nucleolus | Journal of Cell Science
... gamma-tubulin small complex subunit Dgrip84 is required for structural and functional integrity of the spindle apparatus. Mol. ... Likewise, monopolar spindle formation in HCA66-depleted cells can be explained by the loss of functional γ-tubulin or γ-TuSCs, ... Spindle. Introduction. The centrosome constitutes a major microtubule-organizing centre in animal cells. Microtubules are ... 5A,B). Other proteins of the centrosome and of the spindle pole such as pericentrin, centrin, TPX2, Aurora A or Plk1 were not ...
http://jcs.biologists.org/content/122/8/1134
*  "Centrosome abnormalities and chromosome instability occur together in " by German A. Pihan, Jan Wallace et al.
Moreover, centrosome defects occurred together with mitotic spindle defects, chromosome instability, and high cytologic grade. ... They contribute to mitotic spindle organization and regulate aspects of cytokinesis and cell cycle progression. We and others ... Mitotic Spindle Apparatus; Precancerous Conditions; Prostatic Neoplasms; Uterine Cervical Neoplasms ... They contribute to mitotic spindle organization and regulate aspects of cytokinesis and cell cycle progression. We and others ...
https://escholarship.umassmed.edu/oapubs/358/
*  Patterns of tubulin isotype synthesis and usage during mitotic spindle morphogenesis in Physarum. - Oxford Neuroscience
... are present in the mitotic spindle. The stoichiometry of isotype usage in the mitotic spindle generally reflects the overall ... We have also shown that tubulins synthesized in the G2 period of one cell cycle can be incorporated into the spindles of the ... of the development of spindle microtubules throughout the cell cycle. We have shown that all four tubulin isotypes identified ... a biochemical investigation of the synthesis of the plasmodial tubulin isotypes and their participation in the mitotic spindle ...
https://www.neuroscience.ox.ac.uk/publications/5840
*  Phase transition of spindle-associated protein regulate spindle apparatus assembly. - PubMed - NCBI
Phase transition of spindle-associated protein regulate spindle apparatus assembly.. Jiang H1, Wang S2, Huang Y2, He X3, Cui H4 ... E. Spindle matrix assembly required BuGZ coacervation. YFP-xBuGZ, but not YFP-xBuGZ13S, rescued spindle matrix assembly upon ... Spindle matrix assembly required MT-binding of BuGZ. YFP-xBuGZ, but not YFP-xBuGZΔN, rescued spindle matrix assembly upon ... LB3 intensity of ~30 spindle matrices associated with one or two beads was quantified (C). Less spindle matrix was present in ...
https://www.ncbi.nlm.nih.gov/pubmed/26388440
*  Patent US6526011 - Apparatus and method for controlling velocity of spindle motor in optical ... - Google Patent
A widest signal detector of the apparatus detects the widest pulse width of an eight-to-fourteen modulation (EFM) signal ... of a spindle motor included in an optical disk reproducing system to prevent a forward or backward overrun of a spindle motor ... A narrowest signal detector of the apparatus generates a second status signal representing a status of the narrowest pulse ... with overrun upper limit and lower limit values and generates first and second flag signals braking the rotation of the spindle ...
http://www.google.se/patents/US6526011?hl=sv
*  Chapter 7: RNA, The Genetic Code, Mitosis/Meiosis, and Mendelian Genetics Flashcards - MCAT Biochemistry | Brainscape
Spindle apparatus forms and consists of: *Asters - microtubules of the spindle. *Centrosomes move to opposite sides of the cell ... Centrioles - bundles of microtubules of the spindle apparatus.. * Asters - another name for the microtubules that radiate out ... Prophase 2 = nucleus/nucleolus disappears, spindle apparatus forms. *Metaphase 2 = chromosomes line up at the middle of the ... The spindle apparatus of centrosomes and centrioles pulls the sister chromatids apart. ...
https://www.brainscape.com/flashcards/chapter-7-rna-the-genetic-code-mitosis-me-5268458/packs/6138324
*  3.2.2 - Mitosis and Cell Cycle Flashcards by A Robertson | Brainscape
Centrioles move to opposite poles of cell and spindle fibres are released to form a spindle apparatus. ... Prophase - (Preparation - condensing and spindle formation). * Metaphase - (Middle - chromosomes lined up along middle of cell) ...
https://www.brainscape.com/flashcards/322-mitosis-and-cell-cycle-4865613/packs/5947672
*  User contributions for 96.5.162.193 - Wikipedia
Spindle apparatus ‎ (→‎Spindle structure) *17:03, 20 November 2013 (diff , hist) . . (+6)‎ . . Spindle apparatus ‎ ...
https://en.wikipedia.org/wiki/Special:Contributions/96.5.162.193
*  Genetic Basis Of Life
4. Prokaryotes have a single chromosome with mostly DNA and some associated protein; there is no spindle apparatus. 5. ... b. Non-attached spindle fibers, called polar spindle fibers, can reach beyond the metaphase plate and overlap. 9. Anaphase a. ... 1) Polar spindle fibers lengthen as they slide past each other. 2) Kinetochore spindle fibers disassemble at the kinetochores; ... of the spindle. c. The kinetochores of sister chromatids capture kinetochore spindle fibers. d. Chromosomes move back and forth ...
https://www.slideshare.net/mandalina/genetic-basis-of-life
*  MAD1L1 | Cancer Genetics Web
mitotic cell cycle spindle assembly checkpoint - mitotic metaphase - mitotic prometaphase - mitotic telophase - nuclear pore - ... The spindle assembly checkpoint (SAC) has been established as an important mechanism of driving aneuploidy, which occurs at a ... We conclude that the dual activities of Aurora B and CENP-I generate a molecular switch that maintains a robust spindle ... METHODS: SNPs in the MAD2L1 coding region were discovered by sequencing and impact of MAD1L1 and MAD2L1 variants on spindle ...
http://www.cancerindex.org/geneweb/MAD1L1.htm
*  Function of Golgi-centrosome proximity in RPE-1 cells.
Mitotic Spindle Apparatus. An organelle consisting of three components: (1) the astral microtubules, which form around each ... The centrosome duplicates and, during mitosis, separates to form the two poles of the mitotic spindle (MITOTIC SPINDLE ... We report here the finding of abnormal Golgi apparatus morphology in motor neuron like cells depleted of SMN as well as Golgi ... A network of membrane compartments, located at the cytoplasmic side of the GOLGI APPARATUS, where proteins and lipids are ...
https://www.bioportfolio.com/resources/pmarticle/2346406/Function-of-Golgi-centrosome-proximity-in-RPE-1-cells.html
*  Pitx2 regulates gonad morphogenesis.
Mitotic Spindle Apparatus / metabolism. Organ Size. Ovary / cytology, embryology*. Testis / cytology, embryology. Transcription ... We illustrate how Pitx2 activity directs asymmetrical gonad morphogenesis by controlling mitotic spindle orientation of the ...
http://www.biomedsearch.com/nih/Pitx2-regulates-gonad-morphogenesis/18678914.html
*  System-level feedbacks make the anaphase switch irreversible.
Spindle Apparatus / genetics, metabolism. Grant Support. ID/Acronym/Agency: 1R01GM079207/GM/NIGMS NIH HHS; R01 GM078989/GM/ ... with the two copies of each chromosome attached to opposite poles of the mitotic spindle. The mitotic checkpoint is exquisitely ... chromosomes that are not being pulled in opposite directions by the mitotic spindle activate the checkpoint, but during ...
http://www.biomedsearch.com/nih/System-level-feedbacks-make-anaphase/21617094.html
*  PPT - Chapter 9 Cellular Reproduction PowerPoint Presentation - ID:808111
Sister chromatids are pulled along the spindle apparatus toward the center of the cell. ... a failure of the spindle fibers to move chromosomes during mitosis. * mutations or changes in segments of DNA that control ...
https://www.slideserve.com/alaina/chapter-9-cellular-reproduction
*  8b GUG Quiz - By jenjen001
caused by aging egg spindle apparatus. MC site of involvement in endometriosis. causes chocolate cyst aka endometrioma. ... Solid, MC older, spindle cells w/ fibrous bands. Most important reason fertility dec w/ female age is increasing ?. ...
https://www.sporcle.com/games/jenjen001/8b-gug
*  Traction fibre: toward a "tensegral" model of the spindle. - Semantic Scholar
If valid, this concept has implications for the way the spindle functions and for the spindle's relationship to cytokinesis. ... In an evolutionary context, this argument further suggests that the spindle might originally have evolved as the mechanism by ... 104:613-627] derived from the behaviour and organization of the interphase cell apply to the spindle. ... the remaining intact spindle fibres bowed outwards as they came under increased compression. Thus, severing of k-MTs can lead ...
https://www.semanticscholar.org/paper/Traction-fibre%3A-toward-a-%22tensegral%22-model-of-the-Pickett-Heaps-Forer/70a4cc34b7cf6fe2127ae7c205d1aa52e17a0088
*  Dynamical behavior of APC:Cdc20 concentration versus ti | Open-i
Spindle attachment occurs at t = 2000s (switching parameter u from 1 to 0). For the uncontrolled case (A, B), both variants ... Spindle attachment occurs at t = 2000s (switching parameter u from 1 to 0). For the uncontrolled case (A, B), both variants ... Background: The Mitotic Spindle Assembly Checkpoint ((M)SAC) is an evolutionary conserved mechanism that ensures the correct ... Background: The Mitotic Spindle Assembly Checkpoint ((M)SAC) is an evolutionary conserved mechanism that ensures the correct ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2215771_pone.0001555.g002&req=4
*  The Cell Cycle by Nakerri Roebuck - Photo Book
The spindle apparatus of the microtubles disappears.. 4: Cytokinesis In the Animal cell, the microfilaments pinches the ...
https://www.mixbook.com/photo-books/all/the-cell-cycle-by-nakerri-roebuck-6934266?vk=hQ9IZ8Cyri
*  2A (Organelles & Cytoskeleton) Flashcards by Corey Gray | Brainscape
Organizes flagella and cilia as well as the mitotic and meiotic spindle apparatus; known as basal bodies and centrosomes ...
https://www.brainscape.com/flashcards/2a-organelles-amp-cytoskeleton-3658556/packs/5519322
*  a) Schematic representation of the human ECT2 protein. | Open-i
Spindle Apparatus/metabolism. *cdc42 GTP-Binding Protein/metabolism. *rac1 GTP-Binding Protein/metabolism ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2169345_JCB9909086.f1&req=4
*  Failure of pronuclear migration in dhc-1 (RNAi) embryos | Open-i
C and G) In wild type, the spindle sets up in the cell center and along the longitudinal axis (C, arrowheads point to spindle ... C and G) In wild type, the spindle sets up in the cell center and along the longitudinal axis (C, arrowheads point to spindle ... but orientation of the mitotic spindle was defective. Therefore, cytoplasmic dynein is required for multiple aspects of MTOC ... but orientation of the mitotic spindle was defective. Therefore, cytoplasmic dynein is required for multiple aspects of MTOC ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2164971_JCB9904068.f5&req=4
*  CB NBs do not require APCs for asymmetric cell division | Open-i
CB NB asymmetric divisions occur with a persistent spindle orientation with each new daughter born next to the previous ... CB NB asymmetric divisions occur with a persistent spindle orientation with each new daughter born next to the previous ... CD8∷GFP marks cell membrane, nuclei, and spindle. (inset) Different plane of focus showing nuclear envelope. (E) APC2g10 APC1Q8 ... CD8∷GFP marks cell membrane, nuclei, and spindle. (inset) Different plane of focus showing nuclear envelope. (E) APC2g10 APC1Q8 ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2568018_jcb1830203f01&req=4
*  Plus it
Hatched lines represent the spindle apparatus.. (A) Regular meiosis showing properly paired replicated chromosomes undergoing ... centromere and spindle function, chromatin condensation, and recombination. ...
http://www.plantcell.org/content/26/1/181