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*  Sphingomyelin phosphodiesterase - Wikipedia
Sphingomyelin phosphodiesterase (EC 3.1.4.12, also known as neutral sphingomyelinase, sphingomyelinase, or SMase) is a ... SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin (SM) down into ... "Bacterial toxin closes gate on immune response" 2008-02-13 Sphingomyelin Phosphodiesterase at the US National Library of ... "Structural basis of the sphingomyelin phosphodiesterase activity in neutral sphingomyelinase from Bacillus cereus". J. Biol. ...
https://en.wikipedia.org/wiki/Sphingomyelin_phosphodiesterase
*  Fetal lung maturity testing prevents respiratory distress syndrome
Subsequently, sphingomyelin concentration levels off and lecithin begins to increase, with an abrupt rise at 35 weeks. PI ... In early pregnancy, the concentration of lecithin is very small, while that of sphingomyelin is much greater. Lecithin begins ... At 30 to 32 weeks, lecithin concentration remains relatively low, less than or equal to sphingomyelin. PI concentration is also ... Most of the lipids are phospholipids including lecithin (L), sphingomyelin (S), disaturated lecithin, phophatidyl inositol (PI ...
http://www.clinlabnavigator.com/fetal-lung-maturity-profile.html
*  Sphingomyelin | Define Sphingomyelin at Dictionary.com
Sphingomyelin definition, any of the class of phospholipids occurring chiefly in the brain and spinal cord, composed of ... Origin of sphingomyelin. < New Latin sphingo-, combining form representing Greek sphíngein to draw tight + myelin ... sphingomyelin. from sphingo-, from Greek sphingein to bind + myelin. Collins English Dictionary - Complete & Unabridged 2012 ...
https://www.dictionary.com/browse/sphingomyelin
*  Sphingomyelin Medical Definition | Merriam-Webster Medical Dictionary
Medical definition of sphingomyelin: any of a group of crystalline phosphatides that are obtained especially from nerve tissue ... Resources for sphingomyelin. Time Traveler: Explore other words from the year sphingomyelin first appeared Time Traveler! ... Comments on sphingomyelin. What made you want to look up sphingomyelin? Please tell us where you read or heard it (including ... Post the Definition of sphingomyelin to Facebook Share the Definition of sphingomyelin on Twitter ...
https://www.merriam-webster.com/medical/sphingomyelin
*  Anti-Sphingomyelin Synthase 2 antibody (ab102941) | Abcam
Rabbit polyclonal Sphingomyelin Synthase 2 antibody validated for WB and tested in Human and Mouse. Immunogen corresponding to ... Anti-Sphingomyelin Synthase 2 antibody. See all Sphingomyelin Synthase 2 primary antibodies. ... Anti-Sphingomyelin Synthase 2 antibody (ab102941) at 1/100 dilution + HepG2 cell line lysates at 35 µg. Predicted band size: 42 ... Anti-Sphingomyelin Synthase 2 antibody (ab102941) at 1/100 dilution + Mouse spleen tissue lysates at 35 µg. Predicted band size ...
https://www.abcam.com/sphingomyelin-synthase-2-antibody-ab102941.html
*  Anti-Sphingomyelin Synthase 2 antibody (ab103060) Protocols
Abcam provides specific protocols for Anti-Sphingomyelin Synthase 2 antibody (ab103060) : Western blot protocols, ...
http://www.abcam.com/sphingomyelin-synthase-2-antibody-ab103060-protocols.html
*  Sphingomyelin Phosphodiesterase 1, Acid Lysosomal - CAGS
This enzyme converts sphingomyelin to ceramide, and has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and ... The enzymatic defect results in pathologic accumulation of sphingomyelin and other lipids in the monocyte-macrophage system, ...
http://www.cags.org.ae/ctga/details.aspx?id=677
*  WikiPremed MCAT Course - Phospholipids ( Phosphatidylcholine & Sphingomyelin)
The Lipid Library - Sphingomyelin and Related Lipids. Great comprehensive article on sphingomyelin. At this stage, if you are ... preparing for the MCAT, it may not be wise to try to learn the deeper biochemistry of sphingomyelin, so you might treat the ...
http://www.wikipremed.com/mcat_course.php?code=0402010301000000
*  Nuclear Phosphatidylcholine and Sphingomyelin Metabolism of Thyroid Cells Changes during Stratospheric Balloon Flight
... sphingomyelin synthase, and reverse sphingomyelin synthase was assayed in purified nuclei and the nuclei-free fraction. In ... whereas phosphatidylcholine-specific phospholipase C and sphingomyelin synthase were inhibited, thus inducing sphingomyelin ... Nuclear Phosphatidylcholine and Sphingomyelin Metabolism of Thyroid Cells Changes during Stratospheric Balloon Flight. ... Nuclear sphingomyelin and phosphatidylcholine metabolism is involved in the response to ultraviolet radiation treatment in ...
https://www.hindawi.com/journals/bmri/2009/125412/abs/
*  Sphingomyelin - Wikipedia
The metabolism of sphingomyelin creates many products that play significant roles in the cell. Sphingomyelin consists of a ... The synthesis of sphingomyelin at the plasma membrane by sphingomyelin synthase 2 produces diacylglycerol, which is a lipid- ... The structure of sphingomyelin was first reported in 1927 as N-acyl-sphingosine-1-phosphorylcholine. Sphingomyelin content in ... Ideally, sphingomyelin molecules are shaped like a cylinder, however many molecules of sphingomyelin have a significant chain ...
https://en.wikipedia.org/wiki/Sphingomyelin
*  SMPD4 (sphingomyelin phosphodiesterase 4) - KOMP (Knockout Mouse Project)
OMIM: SPHINGOMYELIN PHOSPHODIESTERASE 4, NEUTRAL MEMBRANE; SMPD4*Gene Ontology: Smpd4 *Mouse Phenome DB: Smpd4 *UCSC: Chr.16: ... sphingomyelin phosphodiesterase 4. Synonyms: 4122402O22Rik, neutral membrane (neutral sphingomyelinase-3). Gene nomenclature, ...
https://www.komp.org/geneinfo.php?geneid=79682
*  Sphingomyelin Synthase 2 Deficiency Attenuates NFκB Activation | Arteriosclerosis, Thrombosis, and Vascular Biology
Both sphingomyelin synthase SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells. J Biol ... Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid ... Sphingomyelin Synthase 2 Deficiency Attenuates NFκB Activation. Tiruneh K. Hailemariam, Chongmin Huan, Jing Liu, Zhiqiang Li, ... Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective ...
http://atvb.ahajournals.org/content/28/8/1519.long
*  IJMS | Free Full-Text | Nuclear Lipid Microdomain as Place of Interaction between Sphingomyelin and DNA during Liver...
During G1/S transition of the cell cycle, sphingomyelin and DNA content is very high and it is strongly reduced after exogenous ... Here, we have reported the ability of the sphingomyelin present in the nuclear microdomain to bind DNA and regulate its ... During the S-phase of the cell cycle, the stimulation of sphingomyelinase and inhibition of sphingomyelin-synthase are ... The activity of sphingomyelinase is stimulated in the first hour after hepatectomy and sphingomyelin-DNA synthesis is strongly ...
http://mdpi.com/1422-0067/14/4/6529
*  Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) ELISA & Assay Kits
Compare and order Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) ELISA Kits. View citations, ... Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) ELISA Kit Sphingomyelin ... Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) ELISA Kit Sphingomyelin ... Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) ELISA Kit Sphingomyelin ...
https://www.antibodies-online.com/neurotrophin-signaling-pathway-pathway-29/smpd2-elisa-kit-18185/
*  Cholesterol relieves the inhibitory effect of sphingomyelin on type II secretory phospholipase A2 | Biochemical Journal
Cholesterol relieves the inhibitory effect of sphingomyelin on type II secretory phospholipase A2. Kamen S. KOUMANOV, Peter J. ... Secretory type II phospholipase A2 (sPLA2) is inhibited by sphingomyelin (SPH); cholesterol either mixed with the model ... Cholesterol relieves the inhibitory effect of sphingomyelin on type II secretory phospholipase A2 ... Cholesterol relieves the inhibitory effect of sphingomyelin on type II secretory phospholipase A2 ...
http://www.biochemj.org/content/336/3/625
*  Possible involvement of sphingomyelin in the regulation of the plasma sphingosine 1-phosphate level in human subjects. | Sigma...
Possible involvement of sphingomyelin in the regulation of the plasma sphingosine 1-phosphate level in human subjects.. [ ... such as serum sphingomyelin (SM) and autotaxin (ATX), remains to be elucidated. We measured S1P using high-performance liquid ...
https://www.sigmaaldrich.com/catalog/papers/25863111
*  Sphingomyelin phosphodiesterase-1 (SMPD1) coding variants do not contribute to low levels of high-density lipoprotein...
Niemann-Pick disease type A and B is caused by a deficiency of acid sphingomyelinase due to mutations in the sphingomyelin ... Sphingomyelin phosphodiesterase-1 (SMPD1) coding variants do not contribute to low levels of high-density lipoprotein ...
https://www.sigmaaldrich.com/catalog/papers/18088425
*  Impact of Sphingomyelin Synthase 1 Deficiency on Sphingolipid Metabolism and Atherosclerosis in Mice | Arteriosclerosis,...
Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells. J Biol ... Sphingomyelin synthase 2 is one of the determinants for plasma and liver sphingomyelin levels in mice. Arterioscler Thromb Vasc ... Objective-Sphingomyelin synthase (SMS) catalyzes the conversion of ceramide to sphingomyelin and sits at the crossroads of ... Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid ...
http://atvb.ahajournals.org/content/32/7/1577
*  Sphingomyelin-enriched microdomains define the efficiency of native Ca2+-triggered membrane fusion | Journal of Cell Science
Saez-Cirion, A., Nir, S., Lorizate, M., Agirre, A., Cruz, A., Perez-Gil, J. and Nieva, J. L. (2002). Sphingomyelin and ... Hydrolysis of sphingomyelin disrupts native raft domains on secretory vesicles. Disruption of microdomains enriched in ... Cholesterol, ceramide, sphingomyelin and all lipid standards for high-performance thin-layer chromatography (HPTLC) were ... Ramstedt, B. and Slotte, J. P. (2002). Membrane properties of sphingomyelins. FEBS Lett. 531, 33-37. ...
http://jcs.biologists.org/content/119/13/2688
*  Sphingomyelin upregulation in mature neurons contributes to TrkB activity by Rac1 endocytosis | Journal of Cell Science
1997). Sphingomyelin depletion in cultured cells blocks proteolysis of sterol regulatory element binding proteins at site 1. ... 1991). Plasma membrane sphingomyelin and the regulation of HMG-CoA reductase activity and cholesterol biosynthesis in cell ... Sphingomyelin upregulation in mature neurons contributes to TrkB activity by Rac1 endocytosis ... Analysis of neuronal lipids at different developmental stages revealed a sharp increase in sphingomyelin (SM) during neuronal ...
http://jcs.biologists.org/content/124/8/1308?ijkey=bca2bb3c0fbb931e1ee50cb73387838ab4940189&keytype2=tf_ipsecsha
*  "The use of Sphingomyelin to protect against UV induced DNA damage in H" by Kevin Campbell
In particular, bovine milk sphingomyelin (SM) is a compound that has the potential to protect against UV damage without any of ... In particular, bovine milk sphingomyelin (SM) is a compound that has the potential to protect against UV damage without any of ... The use of Sphingomyelin to protect against UV induced DNA damage in Human Keratinocytes ...
https://digitalcommons.calpoly.edu/theses/1413/
*  Betamethasone modulation of sphingomyelin hydrolysis up-regulates CTP:cholinephosphate cytidylyltransferase activity in adult...
Betamethasone modulation of sphingomyelin hydrolysis up-regulates CTP:cholinephosphate cytidylyltransferase activity in adult ... Betamethasone modulation of sphingomyelin hydrolysis up-regulates CTP:cholinephosphate cytidylyltransferase activity in adult ... Betamethasone modulation of sphingomyelin hydrolysis up-regulates CTP:cholinephosphate cytidylyltransferase activity in adult ... Betamethasone modulation of sphingomyelin hydrolysis up-regulates CTP:cholinephosphate cytidylyltransferase activity in adult ...
http://www.biochemj.org/content/318/1/333
*  Sphingomyelins | CTD
Sphingomyelins 4.. Chemicals ← Lipids ← Membrane Lipids ← Sphingolipids ← Glycosphingolipids ← Neutral Glycosphingolipids ← ... Sphingomyelins Definition A class of sphingolipids found largely in the brain and other nervous tissue. They contain ...
http://ctdbase.org/detail.go?type=chem&acc=D013109