PSAP gene: MedlinePlus Genetics
The PSAP gene provides instructions for making a protein called prosaposin. Learn about this gene and related health conditions ... Al-Hassnan ZN, Al Dhalaan H, Patay Z, Faqeih E, Al-Owain M, Al-Duraihem A, Faiyaz-Ul-Haque M. Sphingolipid activator protein B ... The saposin B protein works with several enzymes to break down sphingolipids. Its most critical biological role seems to be ... The saposin C protein works with the enzyme beta-glucocerebrosidase to break down another sphingolipid called glucocerebroside ...
Sortilin 1 - Wikipedia
"The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin". The EMBO Journal. 22 (24): 6430- ... This protein is a type I membrane glycoprotein in the vacuolar protein sorting 10 protein (Vps10p) family of sorting receptors ... In addition, two hydrophobic loops have been detected in this domain and act to anchor the protein in the cell membrane. ... Sortilin has also been shown to undergo a conformational change and form a protein dimer in acidic conditions similar to ones ...
Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents | Nature...
Spatial lipidomics revealed an accumulation of highly unsaturated and shortened lipids and reduction of sphingolipids ... Sphingolipid activator protein deficiency in a 16-week-old atypical Gaucher disease patient and his fetal sibling: biochemical ... Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and ... Similar mechanisms have been suggested for the pathogenic spread of tau protein aggregation43. Surprisingly, sphingolipids ...
Molecules | Free Full-Text | The Power of LC-MS Based Multiomics: Exploring Adipogenic Differentiation of Human Mesenchymal...
... employed a multimolecular approach using a two-phase extraction to monitor the crosstalk between lipid metabolism and protein- ... Simultaneous analysis of metabolites, lipids, and proteins in cell culture is challenging due to the compounds chemical ... The enzymatic activity of ganglioside GM2 activator protein strongly depends on the sphingolipid and membrane lipid composition ... This is of special interest, as GM3 gangliosides are part of the sphingolipid metabolism identified by protein-metabolite ...
H-InvDB - Transcript view HIT000426587
Similar to Saposin-C; Co-beta-glucosidase; Glucosylceramidase activator; Sphingolipid activator protein 2; SAP-2;. ...
Protein View HIP000247398
Similar to Saposin-B-Val; Contains: Saposin-B; Cerebroside sulfate activator; CS-ACT; Non-specific activator; Sphingolipid ... Similar to Saposin-B-Val; Contains: Saposin-B; Cerebroside sulfate activator; CS-ACT; Non-specific activator; Sphingolipid ... Similar to Saposin-B-Val; Contains: Saposin-B; Cerebroside sulfate activator; CS-ACT; Non-specific activator; Sphingolipid ... Similar to known protein(Category II).. Similar to known protein (P81405) [Identity/coverage = 88.75%/100.0%] to Sus scrofa ( ...
公益財団法人 内藤記念科学振興
Maturation of sphingolipid activator proteins and glycolipid catabolism in k. o. mice. [K.Sandhoff]. Institute for Organic ... Specificities of GM2 activator protein and GM2A protein. [S. -C. Li]. Tulane University School of Medicine, USA, ... Sphingolipids and neuronal growth [H. Futerman]. Weizmann lnstitute of Science, Israel, Session7. Molecular Approach of ... Sphingolipid transport pathways to the two surfaces of epithelial cells: Involvement of multidrug resistance P-glycoproteins? [ ...
SMART: SapB domain annotation
The domain is named after the small lysosomal proteins, saposins, which serve as sphingolipid hydrolase activator proteins in ... Sphingolipid metabolism. This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. ... Click on the protein counts, or double click on taxonomic names to display all proteins containing SapB domain in the selected ... and not all proteins containing SapB domain. Please note that proteins can be included in multiple pathways, ie. the numbers ...
"Exploration of the Binding Behavior and Function of Saposin B" by Jay Tinklepaugh
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Sphingolipid activator proteins. SMA-PME:. Spinal muscular atrophy with progressive myoclonic epilepsy ... and the use of fusion proteins with CNS-targeting moieties is currently being evaluated as a promising method for enzyme ... øget leukocytantal og erytrocytsedimentationsrate og moderat forhøjet plasmakitotriosidase og C-reaktivt protein (CRP) i ...
INR and COVID-19 severity and mortality: A systematic review with meta-analysis and meta-regression - Fingerprint
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Peripheral demyelination (Concept Id: C0878575)
- MedGen - NCBI
Laboratorio de Genetica Clinica SL - Labs - NIH Genetic Testing Registry (GTR) - NCBI
Sphingolipid activator protein 1 deficiency1 test. *Spinal muscular atrophy with congenital bone fractures 11 test ... Thrombophilia due to protein C deficiency, autosomal dominant1 test. *Thrombophilia due to protein S deficiency, autosomal ... Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins1 test ... Thrombophilia due to activated protein C resistance1 test. * ... Thrombophilia due to protein S deficiency, autosomal recessive1 ...
Factors associated with awareness of literate mothers about newborn screening: A cross-sectional study from a low-middle-income...
Paper - WANFANG MED ONLINE
... stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids.[J].2005,21. ... 2]Qu, Feng,Zheng, Su-Jun,Liu, Shuang,etc.Serum Sphingolipids Reflect the Severity of Chronic HBV Infection and Predict the ... 10]M, Ali,J, Fritsch,H, Zigdon,etc.Altering the sphingolipid acyl chain composition prevents LPS/GLN-mediated hepatic failure ... 4]Mari M,Fernandez-Checa JC.Sphingolipid signalling and liver diseases.[J].2007,27(4). ...
α-TEA-induced death receptor dependent apoptosis involves activation of acid sphingomyelinase and elevated ceramide-enriched...
... and sphingolipid activator protein SAP-C [40]. Recent data show that PKCδ contributes to the translocation and activation of ... Stimulation of acid sphingomyelinase activity by lysosomal lipids and sphingolipid activator proteins. Biol Chem. 2001, 382: ... Whole cell protein extracts were prepared and examined by western blotting as described previously [26]. Proteins at 30-50 μg/ ... The effects of α-TEA on the expression of cell membrane death receptors Fas, DR5 and death adaptor protein FADD as well as ...
PSAP Antibody | Affinity Biosciences LTD|亲科生物官网
Sphingolipid activator protein 1; Sphingolipid activator protein 2; Sulfated glycoprotein 1; Sulfatide/GM1 activator; ... The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. ... sphingolipid activator protein 1); prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy); Prosaposin; ... which are similar to each other and are sphingolipid hydrolase activator proteins. ...
Cancer is an internationally health problem. target and its prospect for - Role of TNFα Signaling pathway
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DeCS 2005 - New terms
Sphingolipid Activator Proteins Proteínas Ativadoras de Esfingolipídeos Proteínas Activadoras de Esfingolípidos alpha-N- ... G(M2) Activator Protein Proteína Ativadora de G(M2) Proteína Activadora de G (M2) ... D12 - Amino Acids, Peptides, and Proteins. 14-3-3 Proteins Proteínas 14-3-3 Proteínas 14-3-3 ... Eosinophil Cationic Protein Proteína Catiônica de Eusinófilo Proteína Catiónica del Eoisinofílo Eosinophil Peroxidase ...
DeCS 2005 - Novos termos
Sphingolipid Activator Proteins Proteínas Activadoras de Esfingolípidos Proteínas de Ligação à Penicilinas Penicillin-Binding ... G(M2) Activator Protein Proteina Activadora de G (M2) Proteína Catiônica de Eusinófilo Eosinophil Cationic Protein Proteina ... Proto-Oncogene Proteins A-raf Proteinas A-raf Proto-Oncogene Proteínas Adaptadoras de Transdução de Sinal Adaptor Proteins, ... Phosphatidylethanolamine Binding Protein Proteinas de Unión a Fosfatidiletanolamina Proteínas 14-3-3 14-3-3 Proteins Proteinas ...
DeCS
DeCS 2005 - New terms
Sphingolipid Activator Proteins Proteínas Ativadoras de Esfingolipídeos Proteínas Activadoras de Esfingolípidos alpha-N- ... G(M2) Activator Protein Proteína Ativadora de G(M2) Proteína Activadora de G (M2) ... D12 - Amino Acids, Peptides, and Proteins. 14-3-3 Proteins Proteínas 14-3-3 Proteínas 14-3-3 ... Eosinophil Cationic Protein Proteína Catiônica de Eusinófilo Proteína Catiónica del Eoisinofílo Eosinophil Peroxidase ...
DeCS 2005 - New terms
Sphingolipid Activator Proteins Proteínas Ativadoras de Esfingolipídeos Proteínas Activadoras de Esfingolípidos alpha-N- ... G(M2) Activator Protein Proteína Ativadora de G(M2) Proteína Activadora de G (M2) ... D12 - Amino Acids, Peptides, and Proteins. 14-3-3 Proteins Proteínas 14-3-3 Proteínas 14-3-3 ... Eosinophil Cationic Protein Proteína Catiônica de Eusinófilo Proteína Catiónica del Eoisinofílo Eosinophil Peroxidase ...
DeCS 2005 - New terms
Sphingolipid Activator Proteins Proteínas Ativadoras de Esfingolipídeos Proteínas Activadoras de Esfingolípidos alpha-N- ... G(M2) Activator Protein Proteína Ativadora de G(M2) Proteína Activadora de G (M2) ... D12 - Amino Acids, Peptides, and Proteins. 14-3-3 Proteins Proteínas 14-3-3 Proteínas 14-3-3 ... Eosinophil Cationic Protein Proteína Catiônica de Eusinófilo Proteína Catiónica del Eoisinofílo Eosinophil Peroxidase ...
DeCS 2005 - New terms
Sphingolipid Activator Proteins Proteínas Ativadoras de Esfingolipídeos Proteínas Activadoras de Esfingolípidos alpha-N- ... G(M2) Activator Protein Proteína Ativadora de G(M2) Proteína Activadora de G (M2) ... D12 - Amino Acids, Peptides, and Proteins. 14-3-3 Proteins Proteínas 14-3-3 Proteínas 14-3-3 ... Eosinophil Cationic Protein Proteína Catiônica de Eusinófilo Proteína Catiónica del Eoisinofílo Eosinophil Peroxidase ...
DeCS 2005 - New terms
Sphingolipid Activator Proteins Proteínas Ativadoras de Esfingolipídeos Proteínas Activadoras de Esfingolípidos alpha-N- ... G(M2) Activator Protein Proteína Ativadora de G(M2) Proteína Activadora de G (M2) ... D12 - Amino Acids, Peptides, and Proteins. 14-3-3 Proteins Proteínas 14-3-3 Proteínas 14-3-3 ... Eosinophil Cationic Protein Proteína Catiônica de Eusinófilo Proteína Catiónica del Eoisinofílo Eosinophil Peroxidase ...
DeCS 2005 - New terms
Sphingolipid Activator Proteins Proteínas Ativadoras de Esfingolipídeos Proteínas Activadoras de Esfingolípidos alpha-N- ... G(M2) Activator Protein Proteína Ativadora de G(M2) Proteína Activadora de G (M2) ... D12 - Amino Acids, Peptides, and Proteins. 14-3-3 Proteins Proteínas 14-3-3 Proteínas 14-3-3 ... Eosinophil Cationic Protein Proteína Catiônica de Eusinófilo Proteína Catiónica del Eoisinofílo Eosinophil Peroxidase ...
DeCS 2005 - Novos termos
Sphingolipid Activator Proteins Proteínas Activadoras de Esfingolípidos Proteínas de Ligação à Penicilinas Penicillin-Binding ... G(M2) Activator Protein Proteina Activadora de G (M2) Proteína Catiônica de Eusinófilo Eosinophil Cationic Protein Proteina ... Proto-Oncogene Proteins A-raf Proteinas A-raf Proto-Oncogene Proteínas Adaptadoras de Transdução de Sinal Adaptor Proteins, ... Phosphatidylethanolamine Binding Protein Proteinas de Unión a Fosfatidiletanolamina Proteínas 14-3-3 14-3-3 Proteins Proteinas ...
DeCS 2005 - New terms
Sphingolipid Activator Proteins Proteínas Ativadoras de Esfingolipídeos Proteínas Activadoras de Esfingolípidos alpha-N- ... G(M2) Activator Protein Proteína Ativadora de G(M2) Proteína Activadora de G (M2) ... D12 - Amino Acids, Peptides, and Proteins. 14-3-3 Proteins Proteínas 14-3-3 Proteínas 14-3-3 ... Eosinophil Cationic Protein Proteína Catiônica de Eusinófilo Proteína Catiónica del Eoisinofílo Eosinophil Peroxidase ...