Recent advances in three-dimensional multicellular spheroid culture for biomedical research - Lin - 2008 - Biotechnology...
3D cellular spheroids as tools for understanding carboxylated quantum dot behavior in tumors, Biochimica et Biophysica Acta ( ... show significantly enhanced viability and functional performance when grown as spheroids. Multicellular spheroids in this ... Nuno M. Oliveira, Cláudia Martins-Cruz, Mariana B. Oliveira, Rui L. Reis, João F. Mano, Coculture of Spheroids/2D Cell Layers ... Elisabete C. Costa, Duarte de Melo-Diogo, André F. Moreira, Marco P. Carvalho, Ilídio J. Correia, Spheroids Formation on Non- ...http://onlinelibrary.wiley.com/doi/10.1002/biot.200700228/abstract
Mammary stem cells and breast cancer--role of Notch signalling. - Nuffield Department of Orthopaedics, Rheumatology and...
Mammary Glands, Human, Mammary Glands, Animal, Spheroids, Cellular, Multipotent Stem Cells, Animals, Humans, Carcinoma, ...https://www.ndorms.ox.ac.uk/publications/649687
Defective FA2H leads to a novel form of neurodegeneration with brain iron accumulation (NBIA).
Neuroaxonal spheroids are also a prominent feature of both PKAN and INAD.8 Other neuropathologic findings observed in NBIA, ... Protective role of endogenous gangliosides for lysosomal pathology in a cellular model of synucleinopathies. Am J Pathol 2009; ... 18 with pleiotropic downstream consequences on fundamental cellular processes including protein and lipid turnover (Fig 3), ... iron deposition Variable Variable Seizures Occasional Occasional Peripheral neuropathy Prominent Absent Neuroaxonal spheroids ...https://www.docme.ru/doc/1922125/defective-fa2h-leads-to-a-novel-form-of-neurodegeneration..
3D cell culture | 3D spheroid culture | 3D drug screening
We offer many matrices and other solutions for 3D cell and spheroid culture ... VitroGel 3D-Advanced hydrogel for 3D cell culture and spheroid culture research. ... Bridge the in vitro and in vivo studies by creating natural cellular environment. ...http://thewellbio.com
'spheroids cellular' Protocols and Video...
Spheroids, Cellular: Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain ... The ability to form spheroids is a characteristic trait of Cultured tumor cells derived from solid Tumors. Cells from normal ... tissues can also form spheroids. They represent an in-vitro model for studies of the biology of both normal and malignant cells ...https://www.jove.com/keyword/spheroids+cellular
The onset of necrosis in a 3D cellular automaton model of EMT6 multi-cellular spheroids - Applicationes Mathematicae - Tom 37,...
The onset of necrosis in a 3D cellular automaton model of EMT6 multi-cellular spheroids. ... model of avascular multi-cellular spheroid growth is presented and analysed for the EMT6/Ro cell line. The model outputs are ... A 3-dimensional (3D) extension to a previously reported scaled 2-dimensional Cellular Automaton (CA) ... found to compare favourably with reported experimentally obtained data for in vitro spheroids of the same cell line. Necrosis ( ...http://pldml.icm.edu.pl/pldml/element/bwmeta1.element.bwnjournal-article-doi-10_4064-am37-1-5
Maintenance of the spheroid organization and properties of glandular progenitor cells by fabricated chitosan based biomaterials...
Salispheres are spheroid cellular organizations derived from SG stem cells. Benefitting from these cellular organizations, SG ... Salispheres are spheroid cellular organizations derived from SG stem cells. Benefitting from these cellular organizations, SG ... Maintenance of the spheroid organization and properties of glandular progenitor cells by fabricated chitosan based biomaterials ... Maintenance of the spheroid organization and properties of glandular progenitor cells by fabricated chitosan based biomaterials ...http://pubs.rsc.org/en/content/articlelanding/2018/bm/c7bm00559h
Ovarian follicle - Wikipedia
An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries. It secretes hormones that influence ...https://en.wikipedia.org/wiki/Ovarian_follicle
JUB is highly upregulated in colorectal cancer (CRC) sp | Open-i
Spheroids, Cellular/pathology. *Transcription Factors/metabolism. *Tumor Cells, Cultured. *Up-Regulation. Related in: ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4317901_cas0105-0660-f1&req=4
Recent advances in bioprinting techniques: approaches, applications and future prospects | Journal of Translational Medicine |...
Numerous materials that can be printed with any dimensions; mild conditions (room temperature); use of cellular spheroids; ... Further increases in cellular activity would facilitate expanded applications of bioprinted liver tissue. Chang et al.  ... Shear and thermal stress also affect the viability of the cellular and protein inks . In piezoelectric technology, drops ... Ultraviolet (UV) light used in traditional laser-assisted printing technology might be damaging to the cellular DNA. Lin et al ...https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-016-1028-0
Interactions between cancer cells and the microvasculature: a rate-regulator for metastasis | SpringerLink
The influence of oxygen on viability and proliferation in cellular spheroids.Int. J. Rad. Oncol. Bio. Phys.,5, 2011-2020.Google ... Nicolson, G. L., Irimura, T., Nakajima, M., Updyke, T. V., andPoste, G., 1984, The cellular interactions of metastatic tumor ... Meromsky, L., Lotan, R., andRaz, A., 1986, Implications of endogeneous tumor cell surface lectings as mediators of cellular ...https://link.springer.com/article/10.1007%2FBF01787020
Distribution and subcellular localization of a water-soluble hematoporphyrin-platinum(II) complex in human bladder cancer cells...
Spheroids, Cellular. MESH. Tissue Distribution. MESH. Urinary Bladder/metabolism. MESH. Urinary Bladder Neoplasms/drug therapy ... Accumulation studies with 2D and spheroid cell cultures revealed that the concentration of PEG-HPPt was 1.7-times higher in J82 ... Despite its high molecular weight, penetration of PEG-HPPt was not restricted to the peripheral cells of the spheroids. ... Fluorescence microscopic analysis showed that PEG-HPPt was localized in essential cellular targets of photodynamic therapy. DNA ...https://epub.uni-regensburg.de/4827/
DiVA - Search result
Cellular spheroids as a micrometastasis model in preclinical tests of boron neutron capture therapy2001In: Frontiers in Neutron ... Penetration of tumor therapy interesting substances in non-vascularized metastases; Review of studies in cellular spheroids2006 ... Cellular processing of 125I- and 111in-labeled epidermal growth factor (EGF) bound to cultured A431 tumor cells2000In: Nuclear ... Cellular effects of HER3-specific affibody molecules2012In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 7, no 6, p. e40023 ...http://uu.diva-portal.org/smash/resultList.jsf?af=%5B%5D&aq=%5B%5B%7B%22personId%22%3A%22larsgedd%22%7D%5D%5D&aqe=%5B%5D&aq2=%5B%5B%5D%5D&language=en&query=
References Anti-Collagen IV antibody (ab6586) | Abcam
Casco M et al. Iron Oxide Nanoparticles Stimulates Extra-Cellular Matrix Production in Cellular Spheroids. Bioengineering ( ... Cellular and biochemical assays. By product type. Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists ... Boutin ME et al. A three-dimensional neural spheroid model for capillary-like network formation. J Neurosci Methods 299:55-63 ( ... Kato T et al. Indomethacin induces cellular morphological change and migration via epithelial-mesenchymal transition in A549 ...https://www.abcam.com/collagen-iv-antibody-ab6586-references.html
Expression levels of stem cell genes and activation of | Open-i
Expression levels of stem cell genes and activation of the Wnt/β-catenin pathway in CD24+ cells.(A) mRNA expression levels of Sox2, Oct4, Nanog, Bmi-1 and Rex-https://openi.nlm.nih.gov/detailedresult.php?img=PMC4067285_pone.0099412.g002&req=4
MeSH Semantic Type: Cell [T025]
Spheroids, Cellular [M0028227]. Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture ... thereby stimulating cellular immunity (IMMUNITY, CELLULAR). When found in the skin they are called LANGERHANS CELLS; when found ... From Bjerkvig, Spheroid Culture in Cancer Research, 1992, p4) * Spheroplasts [M0020295]. Cells, usually bacteria or yeast, ... The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive ...http://www.slicksurface.com/medical-thesaurus/semantic-type/cell.htm
Identification of PADI2 as a potential breast cancer biomarker and therapeutic target | BMC Cancer | Full Text
Next, we show that a PADI inhibitor, Cl-amidine, strongly suppresses the growth of MCF10DCIS monolayers and tumor spheroids in ... was tested in vitro using MCF10DCIS cells grown in 2D-monolayers and 3D-spheroids, and in vivo using MCF10DCIS tumor xenografts ... Carlsson J, Yuhas JM: Liquid-overlay culture of cellular spheroids. Recent Results Cancer Res. 1984, 95: 1-23. 10.1007/978-3- ... Multicellular tumor spheroids were generated using the liquid overlay technique as previously described [22-24]. The spheroids ...https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-12-500
Anchorage-independent multi-cellular spheroids as an in vitro model of growth signaling in Ewing tumors. Oncogene 2002;21:307- ... Thus, the dramatic cellular changes associated with a hypoxic microenvironment have thus far been largely ignored (31). We ... Growing multicellular spheroids was done essentially as described elsewhere (30). Hypoxic and normoxic treatments of 1 × 105 ... Molecular and Cellular Pathobiology Hypoxia Modulates EWS-FLI1 Transcriptional Signature and Enhances the Malignant Properties ...http://cancerres.aacrjournals.org/content/70/10/4015
Oncotarget | The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulators
Liquid-overlay culture of cellular spheroids. Recent Results Cancer Res. 1984; 95: 1-23. ... Possibly this difference reflects a combined effect of the unspecific cellular stress of transfection and the parallel loss of ... Hann A, Gruner A, Chen Y, Gress TM, Buchholz M. Comprehensive analysis of cellular galectin-3 reveals no consistent oncogenic ... The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed ...http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=19882&path%5B%5D=63458
Application of mathematics in biology and medicine (Warsawa, 2008). - Contents
Simon D. Angus, Monika J. Piotrowska Towards a 3D cellular automaton model of multi-cellular spheroids ... Wojciech Borkowski Cellular automata model of macroevolution ...................... 18 Katarzyna Buszko, Katarzyna Piecyk, ...http://www.prometeus.nsc.ru/eng/exhibit/09/09-10-06/cont03f.ssi
Three-dimensional multiscale fiber matrices: Development and characterization for increased HepG2 functional maintenance for...
... robust adherence and proliferated growth on the matrix with the formation of characteristic multi-cellular spheroids. Further, ... A comparison study with regard to physico-chemical characterization, hemocompatibility, cytotoxicity, and cellular ...http://pubs.rsc.org/en/content/articlelanding/2018/bm/c7bm00963a
Small-scale screening of anticancer drugs acting specifically on neural stem/progenitor cells derived from human-induced...
Advances in the formation, use and understanding of multi-cellular spheroids.. Expert Opinion on Biological Therapy 12:1347- ... From these results, cisplatin and etoposide can be classified as fast-acting drugs with early cellular toxicity, while ... Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and ... Development and characterization of a scaffold-free 3D spheroid model of induced pluripotent stem cell-derived human ...https://peerj.com/articles/4187/
Protocols and Video Articles Authored by Kam W. Leong (Translated to Portuguese)
The attached hepatocytes on PVDF/F68-Gal membrane self-assembled into multi-cellular spheroids after 1 day of culture. These ... May, 2005 , Pubmed ID: 15585256 Primary rat hepatocytes self-assemble into multi-cellular spheroids and maintain differentiated ... The preliminarily cellular mechanisms, from the cellular entry to the endosomal release, were investigated by the correlations ... Co-cultured hepatocyte spheroids exhibited significantly higher liver-specific functions as compared to spheroids cultured ...https://www.jove.com/author/Kam+W._Leong?language=Portuguese
3D bioprinting - Wikipedia
In some processes, the cells are encapsulated in cellular spheroids 500μm in diameter. This aggregation of cells does not ... There is a "scaffold-free" model that uses self-assembling spheroids that subjects to fusion and cell arrangement to resemble ... The application of biomimicry in bioprinting involves creating both identical cellular and extracellular parts of organs. For ...https://en.wikipedia.org/wiki/3D_bioprinting
2009 Lecture 21 - CellBiology
spheroid cellular tissue culture structure. * mouse and human ES cells have the capacity to undergo controlled differentiation ...https://cellbiology.med.unsw.edu.au/cellbiology/index.php/2009_Lecture_21