From this investigation, NRF1 and SP3 appeared as transcription factors of importance. Complex epithelial-mesenchymal ... hepatic nuclear factor 1 ( HNF1A), hepatic nuclear factor 4 ( HNF4A), transcription factor 4 ( TCF4), and CCAAT enhancer ... Factor Nuclear 1 de Respiración/genética , Oncostatina M/farmacología , Factor de Transcripción Sp3/genética , Transcriptoma/ ... Analysis of the transcription factors and their regulatory roles during a step-by-step differentiation of induced pluripotent ...
Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons. J Neurosci. 2003 May 1;23(9): ... Pro-oxidants can affect cell transcription activity via changes in redox-sensitive transcription factors. Egr-1 and Sp-1 may ... Redox-sensitive transcription factors EGR-1 and SP1 IN the pathogenesis of experimental gastric ulcer. 24.07.2015 Uncategorized ... Thiel G, Cibelli G. Regulation of life and death by the zinc finger transcription factor Egr-1. J Cell Physiol. 2002 Dec;193(3 ...
His Enhancer study typically links adjacent topics like Sp3 transcription factor.. His most cited work include:. *A tale of ... Transcription factor Sp3 is essential for post-natal survival and late tooth development. ... Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors (19 citations) ... Transcription Factor Sp1 Is Essential for Early Embryonic Development but Dispensable for Cell Growth and Differentiation (491 ...
Sp-3, Sp3, SP 3, SP-3, SP3 transcription factor, transcription factor SP 3, Transcription factor SP3 ... Sp3 has been shown to have to a bifunctional transcription factor that can either stimulates or represses the transcription of ... Sp transcription factor family has a highly conserved DNA-binding domain composed of zinc fingers. The Sp family is comprised ... Sp3 and Sp4 that regulates transcription by binding to consensus GC- and GT-box regulatory elements in the target genes. Sp1, ...
... belong to a large group of zinc finger-containing transcription factors with amino acid sequences resembling the Drosophila gap ... Currently, 17 murine and human KLFs are known to play crucial roles in the regulation of transcription, cell proliferation, ... Pesce, M.; Marin Gomez, M.; Philipsen, S.; Scholer, H.R. Binding of Sp1 and Sp3 transcription factors to the Oct-4 gene ... Crucial transcription factors, including SRY-box transcription factor 9 (SOX9), runt-related transcription factor 2 (RUNX2), ...
Role of cyclooxygenase-2 induction by transcription factor Sp1 and Sp3 in neuronal oxidative and DNA damage response. FASEB J ... The kinetic factors that determine the affinity and selectivity for slow binding inhibition of human prostaglandin H synthase 1 ... Ikeda-Matsuo Y, Ota A, Fukada T, Uematsu S, Akira S, Sasaki Y. Microsomal prostaglandin E synthase-1 is a critical factor of ... Prostaglandin D2 induces nuclear import of the sex-determining factor SOX9 via its cAMP-PKA phosphorylation. EMBO J 2005; 24(10 ...
It inhibits RNA synthesis by interfering with the binding of the transcription factors Sp1 and Sp3 to the DNA. Chromomycin A3 ...
Transcription of the transforming growth factor beta activating integrin beta8 subunit is regulated by SP3, AP-1, and the p38 ... Restoring transcription factor HoxA5 expression inhibits the growth of experimental hemangiomas in the brain. J Neuropathol Exp ... Transforming Growth Factor-β and Interleukin-1β Signaling Pathways Converge on the Chemokine CCL20 Promoter. J Biol Chem. 2015 ... Autophagy induction by SIRT6 through attenuation of insulin-like growth factor signaling is involved in the regulation of human ...
... expression through p38 mitogen-activated protein kinase-dependent activation of the Sp1/Sp3 transcription factors in human ... found that E2-2, a basic HLH transcription factor, can suppress expression of vascular endothelial growth factor receptor 2 ( ... transcription factors [11-13]. Mechanistically, Id proteins dimerize with bHLH factors to repress their functions. Id proteins ... The FOXM1 transcription factor interacts with Sp1 to mediate EGF-dependent COX-2 expression in human glioma cells. Mol Cancer ...
Furthermore, a continuous decrease of in vivo bound transcription initiation factors to the CD3 γ promoter was observed after ... HTLV-I infected cells demonstrating that adequate amounts of the required transcription factors were available. We next looked ... It has been shown that Sp1 and Sp3 transcription factor binding to TRE-I repeat III participates in the regulation of HTLV-I ... Transcription factor accessibility to the CD3 γ promoter after HTLV-I infection. A,In vitro binding to the Spγ 1 /CD3γ Inr [22 ...
... and activating transcription factor-2 and c-Jun were bound to a CRE site. Both Sp1 and CRE sites were essential for the full ... Competitive gel shift and supershift assays indicated that Sp2 and Sp3 were bound to an Sp1 site (-40/-31), ...
RE1 silencing transcription factor, Sfrp5 - secreted frizzled related protein 5, Sox6 - SRY-box transcription factor 6, Sp3 - ... Transcription factor; regulation of developmental processes of the heart, cardiac myocyte proliferation, differentiation and ... being derived from pre-cardiac mesoderm are modulated by transcription factor MESP1 as well as other dependent factors, ... The expression of miR-1 and miR-133 in the embryonic heart is regulated by transcription factors SRF, MEF2, myogenic regulatory ...
... type I collagen expression in normal and scleroderma fibroblasts through interaction with Sp1 and Sp3 transcription factors. J ... Regulation of the human Sox9 promoter by the CCAAT-binding factor. Matrix Biol. 2005 May; 24(3):185-97. PMID: 15908194. ... Abrogation of transforming growth factor-ß-induced tissue fibrosis in mice with a global genetic deletion of Nox4. Lab Invest. ... The role of allograft inflammatory factor 1 in systemic sclerosis. Curr Opin Rheumatol. 2006 Nov; 18(6):588-93. PMID: 17053503. ...
keywords = "Cancer, Sp1, Sp2, Sp3, Sp4, Transcription factors, VEGF",. author = "Stephen Safe and Maen Abdelrahim", ... Safe, S., & Abdelrahim, M. (2005). Sp transcription factor family and its role in cancer. European Journal of Cancer, 41(16), ... Sp transcription factor family and its role in cancer. In: European Journal of Cancer. 2005 ; Vol. 41, No. 16. pp. 2438-2448. ... Safe, S & Abdelrahim, M 2005, Sp transcription factor family and its role in cancer, European Journal of Cancer, vol. 41, no ...
Transcription factor. Regulator family:. LacI. Regulation mode:. repressor. Biological process:. Fructooligosaccharides ... Propagation of BfrR regulog to Streptococcus pneumoniae SP3-BS71. Reference regulog properties. Source regulog:. BfrR - ... Predicted regulatory interactions in Streptococcus pneumoniae SP3-BS71. Locus tag. Position. Score. Sequence. ...
It has been demonstrated that two transcription factors, Sp1 and Sp3 bind to the Dp71 promoter to activate transcription of ... 9A). Ectopic transcription was observed in a region normally located 2 Mb farther toward the centromere on the plus strand 100 ... Though not disrupted in LRMD dogs but only inverted, the transcription of this gene could be perturbed, and this would have to ... The level and pattern of transcription across this ~ 0.3 Mb region was similar to DMD large introns, suggesting the causal ...
... sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ... Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid ... Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace ... Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response ...
Sp3 Transcription Factor. Nian H, Delage B, Pinto JT, Dashwood RH. 2008. Allyl mercaptan, a garlic-derived organosulfur ... Sp1 Transcription Factor. Nian H, Delage B, Pinto JT, Dashwood RH. 2008. Allyl mercaptan, a garlic-derived organosulfur ... Transcription, Genetic. Nian H, Delage B, Pinto JT, Dashwood RH. 2008. Allyl mercaptan, a garlic-derived organosulfur compound ... Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 ...
Maternal smoking is a risk factor for pediatric lung disease, including asthma. Animal models suggest that maternal smoking ... Stimulation of vascular endothelial growth factor gene transcription by all trans retinoic acid through Sp1 and Sp3 sites in ... and/or by modulating the activity of transcription factors such as hypoxia-inducible factor-1α [87]or Sp1 [88, 89], as is the ... and activation of transcription factors TTF-1 [93, 94], signal transducers and activators of transcription-3 (STAT3), and Janus ...
Sp1 and Sp3 Are Oxidative Stress-Inducible, Antideath Transcription Factors in Cortical Neurons ... This effect of dopamine serves as a critical factor for the NMDA-independent, postsynaptic Ca2+-dependent induction of LTD ( ...
The transcription factors, stimulatory proteins 1 and 3 (Sp1 and Sp3), nuclear factor Y (NF-Y), upstream stimulatory factor ( ... The transcription factors, stimulatory proteins 1 and 3 (Sp1 and Sp3), nuclear factor Y (NF-Y), upstream stimulatory factor ( ... The transcription factors, stimulatory proteins 1 and 3 (Sp1 and Sp3), nuclear factor Y (NF-Y), upstream stimulatory factor ( ... The transcription factors, stimulatory proteins 1 and 3 (Sp1 and Sp3), nuclear factor Y (NF-Y), upstream stimulatory factor ( ...
... that survivin was over-expressed partially through the up-regulation of protein translation instead of gene transcription in ... and prostate-derived Ets transcription factor (PDEF) [31-33]. Importantly, Hsp90 interferes with sp1, sp3, p53 and Rb ... Xu R, Zhang P, Huang J, Ge S, Lu J, Qian G: Sp1 and Sp3 regulate basal transcription of the survivin gene. Biochem Biophys Res ... Literatures revealed that the rate of survivin gene transcription is positively regulated by molecules such as sp1, sp3 and Myc ...
Sp transcription elements like Sp1 Sp3 and Sp4 have an effect on multiple cellular procedures and also have been involved with ... Objective Increased activity of Sp family of transcription factors is a. * Post author By colinsbraincancer ... Objective Increased activity of Sp family of transcription factors is a frequent and essential event in cancer development and ... The kinesin spindle protein (KSP) a microtubule electric motor protein is → History The epidermal growth factor receptor (EGFR ...
Sp Transcription Factors Research with this laboratory has focused on developing anticancer medicines that downregulate Sp1 Sp3 ... Sp Transcription Factors Members of the Sp/KLF family have a highly conserved DNA binding website that consists of three ... Part of ROS in Drug Mediated KT3 tag antibody Dowregulation of Sp Transcription Factors Studies with this laboratory have shown ... To this effect our laboratory has focused on specificity protein (Sp) transcription factors (TFs) since Sp1 and additional Sp ...
... sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ... Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace ... Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response ...
... sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ... Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace ... Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response ...
Sp1 Transcription Factor. *Sp2 Transcription Factor. *Sp3 Transcription Factor. *Sp4 Transcription Factor ... "Sp4 Transcription Factor" by people in this website by year, and whether "Sp4 Transcription Factor" was a major or minor topic ... "Sp4 Transcription Factor" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... A specificity protein transcription factor that is expressed primarily in the CENTRAL NERVOUS SYSTEM. ...
Binding site transcription factor text structure * two GC boxes. * binding sites for SP1/SP3 and NFY ... functions as a coactivator of several transcription factors * implicated in molecular events that are pivotal to endothelial ... transcriptional coactivator for transcription factors such as FTZ-F1,GCN4,SF1 (NR5A1) ... nucleotide, transcription, regulation PHYSIOLOGICAL PROCESS development text * repression of endothelial cells differentiation ...
keywords = "Angiogenesis, Metastasis, Sp1 transcription factor, Transcriptional control, Tumor suppressor gene",. author = " ... to which Sp1 and Sp3 factors bind. Other regulatory events, such as DNA methylation of the RECK promoter and histone ... to which Sp1 and Sp3 factors bind. Other regulatory events, such as DNA methylation of the RECK promoter and histone ... to which Sp1 and Sp3 factors bind. Other regulatory events, such as DNA methylation of the RECK promoter and histone ...