SoxB1 transcription factors restrict organizer gene expression by repressing multiple events downstream of Wnt signalling |...
Sox3 is one of the earliest of the SoxB1 family of transcription factors to be expressed during vertebrate development. In most ... SoxB1 transcription factors restrict organizer gene expression by repressing multiple events downstream of Wnt signalling ... In this study we describe data that support such a role for members of the SoxB1 family of transcription factors. ... SoxB1 transcription factors restrict organizer gene expression by repressing multiple events downstream of Wnt signalling ...http://dev.biologists.org/content/137/16/2671
SoxB1 transcription factors and Notch signaling use distinct mechanisms to regulate proneural gene function and neural...
SoxB1 transcription factors and Notch signaling use distinct mechanisms to regulate proneural gene function and neural ... SoxB1 transcription factors and Notch signaling use distinct mechanisms to regulate proneural gene function and neural ... SoxB1 transcription factors and Notch signaling use distinct mechanisms to regulate proneural gene function and neural ... SoxB1 transcription factors and Notch signaling use distinct mechanisms to regulate proneural gene function and neural ...http://jcs.biologists.org/content/121/10/e1007
Significant quantitative and qualitative transition in pituitary stem / progenitor cells occurs during the postnatal...
We reported recently that a pituitary-specific transcription factor PROP1 is present in SOX2-positive cells and disappears at ... 0/DNA Primers; 0/SOXB1 Transcription Factors; 0/Sox2 protein, rat Comments/Corrections. ... these endocrine cells are terminally differentiated under control of numerous signalling factors and transcription factors ... To date, many transcription factors important for pituitary organogenesis, such as HESX1/RPX, PTX1, TBX19, LHX3, LHX4, GATA2, ...http://www.biomedsearch.com/nih/Significant-Quantitative-Qualitative-Transition-in/21815952.html
Development of single mouse blastomeres into blastocysts, outgrowths and the establishment of embryonic stem cells.
0/Biological Markers; 0/CDX2 protein, human; 0/Homeodomain Proteins; 0/SOXB1 Transcription Factors; 0/Sox2 protein, mouse; 0/ ...http://www.biomedsearch.com/nih/Development-single-mouse-blastomeres-into/18502895.html
Acquisition of pluripotency in the chick embryo occurs during intrauterine embryonic development via a unique transcriptional...
Background Acquisition of pluripotency by transcriptional regulatory factors is an initial developmental event that is required ... Another core transcription factor, Sox2, which belongs to the SoxB1 subfamily of genes , is also essential for the ... Miyagi S, Kato H, Okuda A. Role of SoxB1 transcription factors in development. Cell Mol Life Sci. 2009;66:3675-84.CrossRef ... The SOX transcription factors as key players in pluripotent stem cells. Stem Cells Dev. 2014;23:2687-99.CrossRefPubMedGoogle ...https://rd.springer.com/article/10.1186/s40104-018-0246-0
Fish development - Wikipedia
Extrinsic signals involved are BMP, Wnt, and FGF and intrinsic transcription factors like SoxB1 related genes. Secreted ... have shown that neural formation relies on interactions between extrinsic signaling factors and intrinsic transcription factors ... Once zygotic gene transcription starts, slow cell division begins and cell movements are observable. During this time three ... BMP2B induces cells to have ventral and lateral fates while factors such as chordin can block BMP's to dorsalize the tissue. ...https://en.wikipedia.org/wiki/Fish_development
SOX1 (Sex determining region Y-box 1) antibody
SOX-1 is a 39 kDa transcription factor that belongs to the SOXB1 subgroup. Within the developing CNS, SOX1 maintains neural ... The SOX (SRY-box containing gene) gene family encodes a group of transcription factors defined by the conserved high motility ...https://www.neuromics.com/GT15208
SOX1 gene - Semantic Scholar
Sox1, Sox2 and Sox3, the three members of the SoxB1 subgroup of transcription factors, have similar sequences, expression… ( ... The transcription factor Sox1 is the earliest and most specific known marker for mammalian neural progenitors. During fetal… ( ... Activation of the first lens-specific gene of the chicken, delta 1-crystallin, is dependent on a group of lens nuclear factors ... Little is known about the molecular mechanisms and intrinsic factors that are responsible for the emergence of neuronal subtype ...https://www.semanticscholar.org/topic/SOX1-gene/1368432
Oman Medical Journal-Archive
Cancer Stem Cells; Cervical Cancer; Oct-4 Transcription Factor; Radiation Tolerance; SOXB1 Transcription Factors. ... Transcription factors Sry-related HMG box (SOX2) and octamer binding transcription factor 4 (OCT4) can confer pluripotent cell ... octamer binding transcription factor 4; Chk1: checkpoint kinase 1;. hTERT: human telomerase reverse transcription. ... octamer binding transcription factor 4; Chk1: checkpoint kinase 1;. hTERT: human telomerase reverse transcription. ...http://omjournal.org/articleDetails.aspx?coType=1&aId=2469
Transcription Factors Medicine & Life Sciences Cardiac Myocytes Medicine & Life Sciences Gene Expression Medicine & Life ...https://utsouthwestern.pure.elsevier.com/en/organisations/molecular-biology-2
a) In the ectoderm of sea urchin embryos, the SoxB1 transcription factor is an activating input into the nodal and emx genes. ... Modular arrays of transcription factor target sites within the cis‐regulatory domains of genes determine the transcription of ... Regulatory genes are sequence‐specific transcription factors that activate or repress transcription and signalling molecules ... called transcription factors, leading to activation or repression of transcription. The interactions among regulatory genes ...http://www.els.net/WileyCDA/ElsArticle/refId-a0001170.html
Inhibitory effect of DC120 on cancer stem-like SP cells | Open-i
SOXB1 Transcription Factors/metabolism*. *Thiazoles/chemistry*. Minor. *Adenosine Triphosphate/chemistry. *Animals. * ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4466661_oncotarget-06-6944-g003&req=4
SOX1 - Wikipedia
The SOX gene family encodes transcription factors. It is suggested the three members of the SOXB1 group have redundant roles in ... SOX1, SOX2, and SOX3, members of the SOX gene family in particular the SOXB1 group, contain transcription factors related to ... In ectodermal cells committed to a certain cell fate, SOX1 has shown to be one of the earliest transcription factors expressed ... SOX1 is a gene, which encodes a transcription factor in the HMG (high mobility group) DNA binding domain, and functions ...https://en.wikipedia.org/wiki/SOX1
Search | eLife
Genetic manipulations show that endogenous transcription factors of the SoxB1 class act redundantly to maintain primed ... Distinct SoxB1 networks are required for naïve and primed pluripotency Andrea Corsinotti et al. ... and patterning of anterior-posterior axis in mouse embryonic development are mediated by pluripotency transcription factor ...https://elifesciences.org/search?for=epiblast
Protocols and Video Articles Authored by Monica L. Vetter (Translated to Danish)
The formation and maintenance of neural-competent precursors are regulated by SoxB1 transcription factors, and evidence that ... transcription factors of the T-cell-specific transcription factor/lymphoid enhancer binding factor (TCF/LEF) family are a class ... 2011 , Pubmed ID: 21529371 Early B cell factor (EBF) family members are transcription factors known to have important roles in ... The ETS Transcription Factor Etv1 Mediates FGF Signaling to Initiate Proneural Gene Expression During Xenopus Laevis Retinal ...https://www.jove.com/author/Monica+L._Vetter?language=Danish
Protocols and Video Articles Authored by Scott Magness (Translated to Arabic)
... a SOXB1-HMG box transcription factor. However, at present, the molecular or cellular mechanisms responsible for these ... Sep, 2005 , Pubmed ID: 15905413 The transcription factor nuclear factor-kappaB (NF-kappaB) is activated during liver ... We show that SOX2, an HMG box transcription factor, is expressed in multipotent neural stem cells at all stages of mouse ... 1950). Aug, 2004 , Pubmed ID: 15265883 NF-kappa B is a family of transcription factors involved in regulating cell death/ ...https://www.jove.com/author/Scott_Magness?language=Arabic
Geometric control of ciliated band regulatory states in the sea urchin embryo | Development
SoxB1 is a pan-ectodermal transcription factor that is known to affect many other regulatory genes of the oral and aboral ... Furthermore, SoxB1 evidently represses otxβ1/2 transcription. However, most of its target genes utilize SoxB1 as a ... SoxB1 controls its own level of expression through negative feedback on the soxb1 gene, so that soxb1 MASO produces a large ... 2004). SpHnf6, a transcription factor that executes multiple functions in sea urchin embryogenesis. Dev. Biol. 273, 226-243. ...http://dev.biologists.org/content/142/5/953
A new role of hindbrain boundaries as pools of neural stem/progenitor cells regulated by Sox2 | BMC Biology | Full Text
Miyagi S, Kato H, Okuda A. Role of SoxB1 transcription factors in development. Cell Mol Life Sci. 2009;66(23):3675-84.PubMed ... SRY-related HMG-box 2 gene (Sox2), a member of the SoxB transcription factor family [45-47], is a fundamental factor in self- ... The expression of the bHLH transcription factors Her5 (in zebrafish) or Hes1/3 (in mice), two genes that act to inhibit neural ... bHLH transcription factor Her5 links patterning to regional inhibition of neurogenesis at the midbrain-hindbrain boundary. ...https://0-bmcbiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s12915-016-0277-y
Antibody Review - Stem Cell Markers
a transcription factor from the SoxB1 subgroup and widely used marker of neural stem cells. PMID: 16797497. ...http://antibodybeyond.com/reviews/cell-markers/stem-cell-marker.htm
Sox3 regulates both neural fate and differentiation in the zebrafish ectoderm. - Radcliffe Department of Medicine
Sox3 is one of the earliest transcription factors to be expressed in the developing CNS and has been shown to be regulated by ... SOXB1 Transcription Factors, Signal Transduction, Skull, Transcription Factors, Zebrafish ... Sox3 is one of the earliest transcription factors to be expressed in the developing CNS and has been shown to be regulated by ... Fibroblast Growth Factors, Gene Expression Regulation, Developmental, High Mobility Group Proteins, Molecular Sequence Data, ...https://www.rdm.ox.ac.uk/publications/106964
Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal. - PubMed - NCBI
SOXB1 Transcription Factors/genetics. *SOXB1 Transcription Factors/metabolism. *Signal Transduction*/drug effects ... Basic Helix-Loop-Helix Transcription Factors/genetics. *Basic Helix-Loop-Helix Transcription Factors/metabolism* ...https://www.ncbi.nlm.nih.gov/pubmed/21685894?dopt=Abstract
Lgr5-positive supporting cells generate new hair cells in the postnatal cochlea. - PubMed - NCBI
SOXB1 Transcription Factors. *Amyloid Precursor Protein Secretases. *Alanine. Grant support. *R01 DC007174/DC/NIDCD NIH HHS/ ...https://www.ncbi.nlm.nih.gov/pubmed/?term=Lgr5-positive%20supporting%20cells%20generate%20new%20hair%20cells%20in%20the%20postnatal%20cochlea
Human chorionic villus mesenchymal stromal cells reveal strong endothelial conversion properties. - Nuffield Department of...
Remarkably, in the presence of pro-angiogenic factors, CVStC reprogrammed toward an endothelial-like phenotype at significantly ... CVStC cultured either in MM or AM presented stromal morphology and immunophenotype, were negative for pluripotency factors ( ... Octamer Transcription Factor-3, SOXB1 Transcription Factors, Mesenchymal Stromal Cells, Nanog Homeobox Protein ... CVStC cultured either in MM or AM presented stromal morphology and immunophenotype, were negative for pluripotency factors ( ...https://www.ndorms.ox.ac.uk/publications/568735
Alvaro Laga | Harvard Catalyst Profiles | Harvard Catalyst
SOXB1 Transcription Factors. *Skin Neoplasms. *Coxsackievirus Infections. See all (226) concept(s) ... Expression of the embryonic stem cell transcription factor SOX2 in human skin: relevance to melanocyte and merkel cell biology ... Fundamentals of Clinical and Translational Research (FaCToR) Online course that offers an overview of clinical research and the ... Histopathologic spectrum of psoriasiform skin reactions associated with tumor necrosis factor-a inhibitor therapy. A study of ...https://connects.catalyst.harvard.edu/Profiles/display/Person/46193
phosphatidylethanolamine binding protein
soxb1 transcription factors*annexin a7*amidinotransferases*cell matrix junctions*humans*choline o acetyltransferase*saussurea* ... yy1 transcription factor*proto oncogene proteins b raf*hmga2 protein*i kappa b kinase*cardiac myosins*sperm capacitation* ... 0474). The clinical relevance of RKIP expression as an independent prognostic factor is restricted to the tumour centre. Loss ... Potentiation of tumor necrosis factor-alpha-induced tumor cell apoptosis by a small molecule inhibitor for anti-apoptotic ...http://www.labome.org/topics/and/peptides/intracellular/phosphatidylethanolamine-binding-protein-13946.html