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... the mass spectrometry revealed a novel potential association between the GABABR and the solute carrier family 12, member 5 ... 2001) Association of GABA(B) receptors and members of the 14-3-3 family of signaling proteins. Mol Cell Neurosci 17:317-328. ... 2010) Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits. Nature 465:231-235. doi:10.1038/ ... Calibration: 100 pA, 1 s. B, Example I-V plot from the same cell in A recorded after 10 min of bath application of the GABABR ...
http://www.jneurosci.org/content/37/22/5447
*  Adenine Nucleotide Translocator 1 Summary Report | CureHunter
Adenine Nucleotide Translocator 1: A subtype of mitochondrial ADP, ATP translocase found primarily in heart muscle (MYOCARDIUM ... Solute Carrier Family 25(Mitochondrial Carrier; Adenine Nucleotide Translocator), Member 4; ANT 1 Transport Protein; Transport ... Carrier Proteins: 11456*Membrane Transport Proteins: 165*Nucleobase, Nucleoside, Nucleotide, and Nucleic Acid Transport ... 05/01/2002 - "In one Japanese autosomal dominant progressive external ophthalmoplegia family, we found a novel A-to-G ...
http://www.curehunter.com/public/keywordSummaryD033741-Adenine-Nucleotide-Translocator-1.do
*  Lipid bilayer composition influences small multidrug transporters | BMC Biochemistry | Full Text
EmrE is the best characterised family member and seems to function as a dimer [4, 8-13]. ... Chen CC, Wilson TH: The phospholipid requirement for activity of the lactose carrier of Escherichia Coli. J Biol Chem. 1984, ... Lande MB, Donovan JM, Zeidel ML: The relationship between membrane fluidity and permeabilities to water, solutes, ammonia, and ... Paulsen I, Skurray R, Tam R, Saier M, Turner R, Weiner J, Goldberg E, Grinius L: The SMR family: a novel family of multidrug ...
https://bmcbiochem.biomedcentral.com/articles/10.1186/1471-2091-9-31
*  SLC12A1 - Solute carrier family 12 member 1 - Homo sapiens (Human) - SLC12A1 gene & protein
Solute carrier family 12 member 1Add BLAST. 1099. Amino acid modifications. Feature key. Position(s). DescriptionActions. ... Cluster: Solute carrier family 12 member 1. 145. Q13621-3. P55016. G3HRT6. A0A1A6GCA8. A0A1U8BJS5. UPI000905AC12. UPI000B506970 ... sp,Q13621,S12A1_HUMAN Solute carrier family 12 member 1 OS=Homo sapiens GN=SLC12A1 PE=1 SV=2 ... help/family_and_domains_section' target='_top'>More...,/a>,/p>Family & Domainsi. ,p>This subsection of the 'Family and domains ...
http://www.uniprot.org/uniprot/Q13621
*  Solute carrier family 12 member 1
This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010 ...
https://pharos.nih.gov/idg/targets/SLC12A1
*  SLC12A1 Gene - GeneCards | S12A1 Protein | S12A1 Antibody
Solute Carrier Family 12 Member 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - ... Domains & Families for SLC12A1 Gene Gene Families for SLC12A1 Gene. HGNC:. *752 : Solute carriers ... member 1:. *Hs.123116 ... SLC12A1 (Solute Carrier Family 12 Member 1) is a Protein Coding ... Solute carrier family 12 member 1 Protein Accession:. Q13621. Secondary Accessions: *A8JYA2 ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=SLC12A1
*  SLC12A1 gene - Genetics Home Reference
solute carrier family 12 member 1. Enable Javascript to view the expand/collapse boxes.. Printable PDF Open All Close All ... member 1. *solute carrier family 12 (sodium/potassium/chloride transporters), member 1 ... solute carrier family 12 (sodium/potassium/chloride transporter), ... 2009 May;458(1):61-76. doi: 10.1007/s00424-008-0607-1. Epub 2008 Nov 4. Review. ...
https://ghr.nlm.nih.gov/gene/SLC12A1
*  Bumentanide Protocol
Solute Carrier Family 12, Member 1. Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption ... Aid To Families With Dependent Children. Financial assistance provided by the government to indigent families with dependent ... Bumetanide is a selective inhibitor of the Na(+)-K(+)-Cl(-)-co-transporter 1(NKCC1). We studied whether bumetanide could affect ... To assess the potential pharmacokinetic (PK) interactions of bumetanide and dapagliflozin following multiple doses of 1 mg ...
https://www.bioportfolio.com/resources/trial/67366/Bumentanide-Protocol.html
*  Expression of SLC12A1 in cancer - Summary - The Human Protein Atlas
Solute carrier family 12 member 1. Protein classi. Protein class the gene product belongs to according to selected gene lists. ... Solute carrier family 12 member 1 (HGNC Symbol). Entrez gene summary. This gene encodes a kidney-specific sodium-potassium- ... HMC-1. HSkMC. HTCEpi. HTEC/SVTERT24-B. HTERT-HME1. HUVEC TERT2. K-562. Karpas-707. LHCN-M2. MCF7. MOLT-4. NB-4. NTERA-2. PC-3. ... HMC-1. HSkMC. HTCEpi. HTEC/SVTERT24-B. HTERT-HME1. HUVEC TERT2. K-562. Karpas-707. LHCN-M2. MCF7. MOLT-4. NB-4. NTERA-2. PC-3. ...
http://www.proteinatlas.org/ENSG00000074803-SLC12A1/pathology
*  Chlorthalidone - DrugBank
Solute carrier family 12 member 1. Molecular Weight. 121449.13 Da. References. *Overington JP, Al-Lazikani B, Hopkins AL: How ... 1. 3. Completed. Not Available. Cardiovascular Disease (CVD) / Death, Sudden,Cardiac / Heart Arrest / Heart Diseases / High ... 1. Not Available. Completed. Not Available. Cardiovascular Disease (CVD) / Coronary Heart Disease (CHD) / Heart Diseases / High ... 2004-08-12. Not applicable. Canada. Atenolol and Chlorthalidone. Chlorthalidone (25 mg/1) + Atenolol (50 mg/1). Tablet. Oral. ...
https://www.drugbank.ca/drugs/DB00310
*  Human Metabolome Database: Showing metabocard for Bumetanide (HMDB0015024)
4. Solute carrier organic anion transporter family member 1A2. General function:. Involved in transporter activity. Specific ... 8. Solute carrier family 22 member 6. General function:. Involved in ion transmembrane transporter activity. Specific function: ... 9. Solute carrier family 22 member 7. General function:. Involved in transmembrane transport. Specific function:. Mediates ... Solute carrier family 22 member 11. General function:. Involved in transporter activity. Specific function:. Mediates saturable ...
http://www.hmdb.ca/metabolites/HMDB0015024
*  Human Metabolome Database: Showing metabocard for Quinethazone (HMDB0015420)
3. Solute carrier family 12 member 3. General function:. Involved in transport. Specific function:. Electrically silent ... These are compounds containing a quinazoline moiety, which is made up of two fused six-member aromatic rings, a benzene ring ... 2. Solute carrier family 12 member 1. General function:. Involved in transport. Specific function:. Electrically silent ... Solute carrier family 12 member 2. General function:. Involved in transport. Specific function:. Electrically silent ...
http://www.hmdb.ca/metabolites/HMDB15420
*  Anti-SLC12A1/Nkcc2 Antibody
Solute carrier family 12(sodium/potassium/chloride transporters), member 1, also called NKCC2 is specifically found in cells of ... Solute carrier family 12 member 1;Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2;Kidney-specific Na-K-Cl ... Rabbit IgG polyclonal antibody for Solute carrier family 12 member 1(SLC12A1) detection. Tested with WB, IHC-P, IHC-F in Human; ... carrier free antibody available upon request. Concentration. Add 0.2ml of distilled water will yield a concentration of 500ug/ ...
https://www.bosterbio.com/anti-slc12a1-antibody-pa2168.html
*  Reactome | SLC22A12 G361V [plasma membrane]
Solute carrier family 22 member 12, S22AC_HUMAN ... Defective SLC22A12 causes renal hypouricemia 1 (RHUC1) (Homo ...
https://reactome.org/content/detail/R-HSA-5625202
*  Anti-Rind (Kuh) SLC12A2 Antikörper für Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
... member 2 * solute carrier family 12 (sodium/potassium/chloride transporter), member 2 ... Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2) Antikörper Synonyme für dieses Antigen anzeigen * ... Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2) Andere Bezeichnung SLC12A2 / NKCC1 (SLC12A2 ... Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2) Antikörper Reaktivität Rind (Kuh), Hund, Human, ...
http://www.antikoerper-online.de/sensory-perception-of-sound-pathway-54/slc12a2-antibody-15189/cow-ihc-p-151814/
*  TCDB » Human MTPs
sp,Q13621,S12A1_HUMAN Solute carrier family 12 member 1 OS=Homo sapiens GN=SLC12A1 PE=1 SV=2 ... member 1. Symbol: SLC12A1. ... and suggest potential phenotypes in heterozygous carriers of ... solute carrier family 12 (sodium/potassium/chloride transporters), ...
http://tcdb.org/hgnc_explore.php?symbol=SLC12A1
*  Slc12a1 polyclonal antibody (RPE) - (PAB29052) - Products - Abnova
Solute carrier family 12 member 1 (bumetanide-sensitive sodium-[potassium]-chloride cotransporter),Solute carrier family 12, ... member 1. *Gene Ontology: ... Western blot (1:1000). The optimal working dilution should be ... solute carrier family 12 (sodium/potassium/chloride transporters), ... Western blot analysis of rat kidney with Slc12a1 polyclonal antibody (PAB29036) at 1:1000 dilution. ...
http://www.abnova.com/products/products_detail.asp?catalog_id=PAB29052
*  Renal Oncocytoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
aldehyde dehydrogenase 8 family, member A1. Kidney -. 8.58. 0.000. 7. SLC12A1 solute carrier family 12 (sodium/potassium/ ... solute carrier family 7 (anionic amino acid transporter), member 13. Kidney -. 7.29. 0.000. ... solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3. Kidney -. 6.86. 0.000. ... family with sequence similarity 151, member A. Kidney -. 7.15. 0.000. 38. C1S complement component 1, s subcomponent. Kidney - ...
http://www.malacards.org/card/renal_oncocytoma
*  Edema due to Hepatic Cirrhosis
Solute carrier family 12 member 1. Tclin. Transporter. Mineralocorticoid receptor. Tclin. Nuclear Receptor. ...
https://pharos.nih.gov/idg/diseases/IDG:D2059
*  Austin Health Research Online: Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK...
Solute Carrier Family 12, Member 1.metabolism. Appears in Collections:. Journal articles. ... Renal Physiology 2014; 307(1): F96-F106. Abstract: Enhanced tubular reabsorption of salt is important in the pathogenesis of ... oxidative stress responsive 1 kinase. AMP-Activated Protein Kinases.metabolism. Animals. Epithelial Sodium Channels.metabolism ... Activation of STE-20/SPS1-related proline-alanine-rich protein kinase (SPAK)/oxidative stress responsive 1 kinase (OSR1) was ...
http://ahro.austin.org.au/austinjspui/handle/1/12209
*  Alphabetical Browse | Britannica.com
... solute carrier family 12, member 1), whereas type 2 is caused by mutation of the gene KCNJ1 (potassium inwardly rectifying ... member of the Turkic language family (a subfamily of the Altaic languages), belonging to the northwestern, or Kipchak, branch. ... member of the Turkic language family (a subfamily of the Altaic languages), belonging to the northwestern, or Kipchak, branch. ... A member of the Piast dynasty, he drove his brother Mieszko III from the throne and spent much of his reign fighting him. ...
https://www.britannica.com/browse/alpha/k/26
*  Slc47a1 MGI Mouse Gene Detail - MGI:1914723 - solute carrier family 47, member 1
1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 frog, western clawed;1 macaque, rhesus. ... Slc47a1 interacts with 229 markers (Mir7-1, Mir7-2, Mir7b, ...) View All ...
http://www.informatics.jax.org/marker/MGI:1914723
*  SLC22A1 - Solute carrier family 22 member 1 - Homo sapiens (Human) - SLC22A1 gene & protein
Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- ... methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- ... Solute carrier family 22 member 1Add BLAST. 554. Amino acid modifications. Feature key. Position(s). DescriptionActions. ... sp,O15245,S22A1_HUMAN Solute carrier family 22 member 1 OS=Homo sapiens OX=9606 GN=SLC22A1 PE=1 SV=2 ...
https://www.uniprot.org/uniprot/O15245
*  Slc4a1 MGI Mouse Gene Detail - MGI:109393 - solute carrier family 4 (anion exchanger), member 1
SLC4A1, solute carrier family 4 member 1 (Diego blood group). Orthology source: HomoloGene, HGNC ... View 1 model Mouse Models. Human Disease Modeled: renal tubular acidosis. Allelic Composition. Genetic Background. Reference. ... View 1 model Mouse Models. Human Disease Modeled: hereditary spherocytosis type 4. Allelic Composition. Genetic Background. ... 1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed. ...
http://www.informatics.jax.org/marker/MGI:109393