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*  Disopyramide phosphate / disopyramide phosphate NDA 070102 international drug patent coverage, generic alternatives and...
Voltage-Gated Sodium Channel Blockers Suppliers and Packaging for NDA: 070102. Tradename. Generic Name. Dosage. NDA. ...
https://www.drugpatentwatch.com/p/NDA/070102
*  Disopyramide - Wikipedia
It is a sodium channel blocker and therefore classified as a Class 1a anti-arrhythmic agent. Disopyramide has a negative ... Disopyramide's Class 1a activity is similar to that of quinidine in that it targets sodium channels to inhibit conduction. ... Beta-blockers are used first, and while they improve symptoms of shortness of breath, chest pain and exercise intolerance, they ... Disopyramide depresses the increase in sodium permeability of the cardiac myocyte during Phase 0 of the cardiac action ...
https://en.wikipedia.org/wiki/Disopyramide
*  Sodium channel blocker - Wikipedia
Sodium channel blockers are drugs which impair the conduction of sodium ions (Na+) through sodium channels.[1] ... Sodium channel opener. References[edit]. *^ Sodium+Channel+Blockers at the US National Library of Medicine Medical Subject ... sodium channels.[3]. Antiarrhythmic[edit]. Sodium channel blockers are used in the treatment of cardiac arrhythmia. They are ... "Sodium channel blockers for cystic fibrosis".. *^ Dick IE, Brochu RM, Purohit Y, Kaczorowski GJ, Martin WJ, Priest BT (April ...
https://en.wikipedia.org/wiki/Sodium_channel_blockers
*  What Is a Sodium Channel Blocker? (with pictures)
A sodium channel blocker is a medication that is used to correct abnormal heart rhythms by affecting the electrical impulses ... A sodium channel blocker is a medication that is categorized as a Class I antiarrhythmic drug. This means that it works to ... Typically, a sodium channel blocker may cause dizziness, nausea, and vomiting, along with diarrhea or constipation. Loss of ... People taking a sodium channel blocker may experience some side effects, which should be reported to the prescribing physician ...
https://www.wisegeek.com/what-is-a-sodium-channel-blocker.htm
*  Sodium channel blocker - Wikipedia
Sodium channel blockers are drugs which impair the conduction of sodium ions (Na+) through sodium channels. The following ... Sodium channel blockers are also used as local anesthetics and anticonvulsants. Sodium channel blockers have been proposed for ... Sodium channel opener Sodium Channel Blockers at the US National Library of Medicine Medical Subject Headings (MeSH) Armstrong ... is known to block sodium channels but its not known whether its extracellular or intracellular Sodium channel blockers are used ...
https://en.wikipedia.org/wiki/Sodium_channel_blocker
*  Epithelial sodium channel blocker - Wikipedia
An epithelial sodium channel blocker is a sodium channel blocker that is selective for the epithelial sodium channel. An ... Sagnella GA, Swift PA (2006). "The renal epithelial sodium channel: genetic heterogeneity and implications for the treatment of ...
https://en.wikipedia.org/wiki/Epithelial_sodium_channel_blocker
*  Selective sodium channel blockers in trigeminal neuralgia - Research - Aarhus University
Selective sodium channel blockers in trigeminal neuralgia Selective sodium channel blockers in trigeminal neuralgia. Research ... Selective sodium channel blockers in trigeminal neuralgia. / Jensen, Troels Staehelin.. In: Lancet Neurology, Vol. 16, No. 4, ... "Selective sodium channel blockers in trigeminal neuralgia". Lancet Neurology. 2017, 16(4). 255-256. Available: 10.1016/S1474- ... Selective sodium channel blockers in trigeminal neuralgia. Lancet Neurology. 2017 Apr;16(4):255-256. Available from, DOI: ...
http://pure.au.dk/portal/en/publications/selective-sodium-channel-blockers-in-trigeminal-neuralgia
*  Efficacy Study of Sodium Channel Blocker in LQT3 Patients - Full Text View - ClinicalTrials.gov
Efficacy Study of Sodium Channel Blocker in LQT3 Patients. This study is currently recruiting participants. See Contacts and ... The purpose of this study is to determine whether late sodium channel blockade might be effective in shortening the QTc ... In vitro studies of specific mutation show no effect of ranolazine on late sodium current kinetics or show repolarization ... Ranolazine shortens repolarization in patients with sustained inward sodium current due to type-3 long-QT syndrome. J ...
https://clinicaltrials.gov/ct2/show/NCT01648205?cond=%22Andersen-Tawil+syndrome%22+OR+%22Long+QT+Syndrome%22&rank=12
*  go-plus - substance with sodium channel blocker role - Classes | NCBO BioPortal
The National Center for Biomedical Ontology was founded as one of the National Centers for Biomedical Computing, supported by the NHGRI, the NHLBI, and the NIH Common Fund under grant U54-HG004028 ...
http://bioportal.bioontology.org/ontologies/GO-PLUS?p=classes&conceptid=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FGOCHE_38633
*  Abstract 1967: A-803467, a sodium channel blocker, reverses ABCG2-mediated MDR | Cancer Research
A-803467, a sodium channel blocker, reverses ABCG2-mediated MDR. [abstract]. In: Proceedings of the 105th Annual Meeting of the ... In this study, we investigated the ability of sodium channel blocker, A-803467 to reverse ABCG2-mediated MDR. We found that A- ... Abstract 1967: A-803467, a sodium channel blocker, reverses ABCG2-mediated MDR. Nagaraju Anreddy ... Abstract 1967: A-803467, a sodium channel blocker, reverses ABCG2-mediated MDR ...
http://cancerres.aacrjournals.org/content/74/19_Supplement/1967
*  Identification of WB4101, an α1-Adrenoceptor Antagonist, as a Sodium Channel Blocker | Molecular Pharmacology
WB4101 as a Sodium Channel Blocker. Min Li, Ying Wu, Beiyan Zou, Xiaoliang Wang, Min Li and Haibo Yu ... WB4101 as a Sodium Channel Blocker. Min Li, Ying Wu, Beiyan Zou, Xiaoliang Wang, Min Li and Haibo Yu ... Identification of WB4101, an α1-Adrenoceptor Antagonist, as a Sodium Channel Blocker. Min Li, Ying Wu, Beiyan Zou, Xiaoliang ... In conclusion, the present study identified WB4101 as a sodium channel blocker with an open-state-dependent property, which may ...
http://molpharm.aspetjournals.org/content/94/2/896
*  Chronic exposure to NMDA receptor and sodium channel blockers during development in monkeys and rats: long-term effects on...
To further explore the roles of NMDA receptors and sodium channels in these effects, MK-801, phenytoin (sodium channel blocker ... Chronic exposure to NMDA receptor and sodium channel blockers during development in monkeys and rats: long-term effects on ... The effects of chronic administration of MK-801 (NMDA-receptor antagonist) and remacemide (sodium channel blocker) on monkey ... In the rat, blockade of sodium channels was well tolerated but blockade of NMDA receptors had significant and long-term ( ...
https://www.sigmaaldrich.com/catalog/papers/12853303
*  Sodium channel blockers and axonal protection in neuroinflammatory disease : Brain - oi
We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time.Find out more ...
http://oxfordindex.oup.com/view/10.1093/brain/awh353
*  Effects of the Sodium Channel Blocker Tetrodotoxin on Acute White Matter Pathology After Experimental Contusive Spinal Cord...
Effects of the Sodium Channel Blocker Tetrodotoxin on Acute White Matter Pathology After Experimental Contusive Spinal Cord ... Effects of the Sodium Channel Blocker Tetrodotoxin on Acute White Matter Pathology After Experimental Contusive Spinal Cord ... Effects of the Sodium Channel Blocker Tetrodotoxin on Acute White Matter Pathology After Experimental Contusive Spinal Cord ... Effects of the Sodium Channel Blocker Tetrodotoxin on Acute White Matter Pathology After Experimental Contusive Spinal Cord ...
http://www.jneurosci.org/content/19/14/6122
*  First Subjects Dosed in Phase 1 Clinical Study of NKTR-171, A New Peripherally-Restricted Sodium Channel Blocker to Treat...
Sodium,Channel,Blocker,to,Treat,Neuropathic,Pain,medicine,advanced medical technology,medical laboratory technology,medical ... A peripherally-restricted sodium channel blocker with good efficacy and low CNS side effects would be an important advance in ... The sodium channel blocker lidocaine is known to be effective in addressing peripheral nerve pain, however it is not selective ... "While conventional sodium channel blockers have demonstrated efficacy in addressing peripheral nerve pain, the CNS-mediated ...
http://www.bio-medicine.org/medicine-technology-1/First-Subjects-Dosed-in-Phase-1-Clinical-Study-of-NKTR-171--A-New-Peripherally-Restricted-Sodium-Channel-Blocker-to-Treat-Neuropathic-Pain-38216-1/
*  Abstract 14948: Clinical Characteristics of Idiopathic Ventricular Fibrillation with Early Repolarization and Response of Early...
... showed attenuation of ER in inferior or lateral leads by sodium channel blocker infusion (94%). Comparing to patients in BS ... provocative tests with sodium-channel blockers were performed in all ERS and BS patients. ... early repolarization in inferior or lateral leads in both ERS and BS patients were attenuated by sodium channel blocker ... of Idiopathic Ventricular Fibrillation with Early Repolarization and Response of Early Repolarization to Sodium Channel Blocker ...
http://circ.ahajournals.org/content/122/Suppl_21/A14948
*  A selective Nav1.8 sodium channel blocker, A-803467, attenuates spinal neuronal activity in neuropathic rats | Journal of...
A selective Nav1.8 sodium channel blocker, A-803467, attenuates spinal neuronal activity in neuropathic rats. Steve McGaraughty ... A selective Nav1.8 sodium channel blocker, A-803467, attenuates spinal neuronal activity in neuropathic rats. Steve McGaraughty ... A selective Nav1.8 sodium channel blocker, A-803467, attenuates spinal neuronal activity in neuropathic rats. Steve McGaraughty ... A selective Nav1.8 sodium channel blocker, A-803467, attenuates spinal neuronal activity in neuropathic rats ...
http://jpet.aspetjournals.org/content/early/2007/12/18/jpet.107.134148
*  Site-1 Sodium Channel Blockers as Local Anesthetics:Will Neosaxitoxin Supplant the Need for Continuous Nerve Blocks? |...
Site-1 Sodium Channel Blockers as Local Anesthetics: Will Neosaxitoxin Supplant the Need for Continuous Nerve Blocks?. ... Site-1 Sodium Channel Blockers as Local Anesthetics: Will Neosaxitoxin Supplant the Need for Continuous Nerve Blocks? ... Site-1 Sodium Channel Blockers as Local Anesthetics: Will Neosaxitoxin Supplant the Need for Continuous Nerve Blocks? ... Laura A. Lahaye, John F. Butterworth; Site-1 Sodium Channel Blockers as Local Anesthetics: Will Neosaxitoxin Supplant the Need ...
https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2430414
*  Effects of the sodium channel blocker amitriptyline on the spontaneous and stimulus-evoked activity of corneal cold-sensitive...
Effects of the sodium channel blocker amitriptyline on the spontaneous and stimulus-evoked activity of corneal cold-sensitive ... Effects of the sodium channel blocker amitriptyline on the spontaneous and stimulus-evoked activity of corneal cold-sensitive ... Takayoshi Masuoka, Carlos Belmonte, Juana Gallar; Effects of the sodium channel blocker amitriptyline on the spontaneous and ... Conclusions: Na+-channel blocker amitriptyline attenuates the spontaneous activity and cooling response of cold nerve terminals ...
https://iovs.arvojournals.org/article.aspx?articleid=2333153
*  Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo...
Download PDF 'Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double- ... Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo ... Background: Current standard of care for trigeminal neuralgia is treatment with the sodium channel blockers carbamazepine and ... Background: Current standard of care for trigeminal neuralgia is treatment with the sodium channel blockers carbamazepine and ...
http://www.zora.uzh.ch/id/eprint/135668/
*  Sodium Channel Blockers - The Group 1 of Antiarrhythmic Drugs | Lecturio
Antiarrhythmic drugs ✓, mechanism of action of sodium channel blockers ✓, disopyramide ✓, quinidine ✓. Read more now! ... This article concerning sodium channel blockers, discusses the class 1 antiarrhythmic drugs in detail, along with a description ... Class 1: Sodium Channel Blockers - Antiarrhythmic Drugs Class 1: Sodium Channel Blockers - Antiarrhythmic Drugs. Last update ... Mechanism of Action of Sodium Channel Blockers. Sodium-channel blockers comprise the Class I antiarrhythmic compounds according ...
https://www.lecturio.com/magazine/sodium-channel-blockers/
*  Antiarrhythmics (Lesson 2 - Sodium Channel Blockers) lesson plan | Spiral
Sodium Channel Blockers) - lesson plan ideas from Spiral. Tagged under: antiarrhythmics,arrhythmia,heart rhythm ... A review of class I antiarrhythmics - the sodium channel blockers (e.g. quinidine, procainamide, lidocaine, mexiletine, ...
https://spiral.ac/sharing/7wqka8c/antiarrhythmics-lesson-2-sodium-channel-blockers
*  Greenwich Academic Literature Archive - Cyclic triazo sodium channel blockers
Cyclic triazo sodium channel blockers Cyclic triazo sodium channel blockers *Repository Statistics ... University of Greenwich (2010) Cyclic triazo sodium channel blockers. 12801937. Full text not available from this repository. ...
https://gala.gre.ac.uk/id/eprint/4318/
*  Voltage-Gated Sodium Channel Blockers Library from OTAVA - pdf descargar
Voltage-Gated Sodium Channel Blockers Library from OTAVA. . Biblioteca virtual para leer y descargar libros, documentos, ... Keywords : voltage-gated sodium channels membrane proteins inhibitors voltage-gated sodium channel blockers ligand-based ... Voltage-Gated Sodium Channel Blockers Library from OTAVA - Descarga este documento en PDF. Documentación en PDF para descargar ... The models were generated based on the known sodium channel blockers divided into three groups according to their structural ...
http://libros.duhnnae.com/2017/jun7/149820380938-Voltage-Gated-Sodium-Channel-Blockers-Library-from-OTAVA.php
*  Indian Patents. 234877:BIARYL SUBSTITUTED 6-MEMBERED HETEROCYCLES AS SODIUM CHANNEL BLOCKERS
... sodium channels are closed. Following membrane depolarization, sodium channels open rapidly and then inactivate.. Sodium ... Indeed, most sodium channel blockers known to date interact with similar potency with all channel subtypes. Nevertheless, it ... Voltage-gated sodium channels represent a multigene family. Nine sodium channel subtypes have been cloned and functionally ... Sodium channel inhibitors will prevent cell depolarization caused by sodium ion movement through agonist-modified sodium ...
http://www.allindianpatents.com/patents/234877-biaryl-substituted-6-membered-heterocycles-as-sodium-channel-blockers