Loading...
*  microRNA-128 regulates the proliferation and differentiation of bovine skeletal muscle satellite cells by repressing Sp1 |...
microRNA-128 regulates the proliferation and differentiation of bovine skeletal muscle satellite cells by repressing Sp1. ... MicroRNAs (miRNAs) play essential roles in muscle cell proliferation and differentiation. The muscle-specific miRNAs miR-1 and ... The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 38:228-233CrossRef ... The role of microRNA-1 and microRNA-206 in the proliferation and differentiation of bovine skeletal muscle satellite cells. In ...
https://link.springer.com/article/10.1007%2Fs11010-016-2656-7
*  Regulation of proliferation and differentiation of myoblasts derived from adult mouse skeletal muscle by specific isoforms of...
Regulation of proliferation and differentiation of myoblasts derived from adult mouse skeletal muscle by specific isoforms of ... Regulation of proliferation and differentiation of myoblasts derived from adult mouse skeletal muscle by specific isoforms of ... in muscle regeneration following muscle trauma by stimulating the proliferation and by inhibiting the differentiation of ... The expression of receptors and the mitogenic response to PDGF by C2 myoblasts, derived from adult mouse skeletal muscle, was ...
http://jcb.rupress.org/content/111/4/1623
*  Gαi2 Signaling Is Required for Skeletal Muscle Growth, Regeneration, and Satellite Cell Proliferation and Differentiation |...
... induces skeletal muscle hypertrophy and myoblast differentiation. To determine whether Gαi2 is required for skeletal muscle ... The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat. Genet. 38:228-233. doi: ... Gαi2 Signaling Is Required for Skeletal Muscle Growth, Regeneration, and Satellite Cell Proliferation and Differentiation. ... Gαi2 Signaling Is Required for Skeletal Muscle Growth, Regeneration, and Satellite Cell Proliferation and Differentiation ...
https://mcb.asm.org/content/34/4/619.long
*  Mir-133 microRNA precursor family - Wikipedia
"The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation". Nat. Genet. 38 (2): 228-33. doi: ... miR-133 suppresses Prdm16 expression in skeletal muscle stem cells (satellite cells), which controls myogenic vs. brown ... miR-133 is expressed in muscle tissue and appears to repress the expression of non-muscle genes. It is proposed that Insulin ... "MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16". Cell Metabolism. 17 ...
https://en.wikipedia.org/wiki/Mir-133_microRNA_precursor_family
*  Cell Cycle Regulation of Stem Cells by MicroRNAs | SpringerLink
2016). The role of microRNA-1 and microRNA-206 in the proliferation and differentiation of bovine skeletal muscle satellite ... 2017). miR-143 regulates proliferation and differentiation of bovine skeletal muscle satellite cells by targeting IGFBP5. In ... 2010). microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7 ... 2017). miR-221 modulates skeletal muscle satellite cells proliferation and differentiation. In Vitro Cellular and Developmental ...
https://link.springer.com/article/10.1007/s12015-018-9808-y
*  Plus it
2006) The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 38:228-233. doi: ... 2010) MicroRNA-mediated control of oligodendrocyte differentiation. Neuron 65:612-626. doi:10.1016/j.neuron.2010.02.018 pmid: ... This progressive loss of MNs results in muscle denervation and atrophy, leading to death within 3-5 years of symptom onset ( ... miR-133a has been studied extensively in the context of muscle (Chen et al., 2006), but this work suggests that it may also ...
http://www.jneurosci.org/content/37/22/5574
*  MicroRNA-328 Contributes to Adverse Electrical Remodeling in Atrial FibrillationClinical Perspective | Circulation
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet. 2006;38:228-233. ... The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat Med. 2007;13:486 ... Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature. 2005;436:214-220. ... Transcriptional activation by stimulating protein 1 and post-transcriptional repression by muscle-specific microRNAs of IKs- ...
http://circ.ahajournals.org/content/122/23/2378
*  Regulated demethylation of the myoD distal enhancer during skeletal myogenesis. - Semantic Scholar
... one of a family of four related basic helix-loop-helix transcription factors involved in the specification and differentiation ... of skeletal muscle. We previously identified a 258-bp distal enhancer that is sufficient for embryonic activation of myoD and ... DNA Methylation in Skeletal Muscle Stem Cell Specification, Proliferation, and Differentiation. *Rhianna C. Laker, James G. ... Ten-Eleven Translocation-2 (Tet2) Is Involved in Myogenic Differentiation of Skeletal Myoblast Cells in Vitro. *Xia Zhong, Qian ...
https://www.semanticscholar.org/paper/Regulated-demethylation-of-the-myoD-distal-enhancer-Brunk-Goldhamer/7d4a6a8e15437a1af93be4f629c5de6e1b93d08c
*  Frontiers | Regulation of hepatitis B virus replication by epigenetic mechanisms and microRNAs | Genetics
2006). The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat. Genet. 38, 228-233. ... 2010). In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice. ... 2011). Modulation of hepatitis B virus replication and hepatocyte differentiation by microRNA-1. Hepatology 53, 1476-1485. doi ... both of these two defined epi-miRNAs could inhibit the G1/S cell cycle transition and promote cell differentiation by ...
https://www.frontiersin.org/articles/10.3389/fgene.2013.00202/full
*  IJMS | Free Full-Text | Deep Sequencing Analysis of miRNA Expression in Breast Muscle of Fast-Growing and Slow-Growing...
To investigate the function of miRNAs in chicken growth, breast muscle tissues of the two-tail samples (highest and lowest body ... The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat. Genet. 2006, 38, 228-233. [ ... A systematic analysis of the skeletal muscle miRNA transcriptome of chicken varieties with divergent skeletal muscle growth ... Different expression levels of miR-21 were found in chicken skeletal muscle of different growth periods [26], and in skeletal ...
https://www.mdpi.com/1422-0067/16/7/16242/html
*  Plus it
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 2006;38:228-33. ... Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle ... Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 2005;436:214-20. ... The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic ...
http://clincancerres.aacrjournals.org/content/18/3/737
*  Overexpression of M3 Muscarinic Receptor Is a Novel Strategy for Preventing Sudden Cardiac Death in Transgenic Mice | Springer...
2006) The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat. Genet. 38:228-33. ... Our previous study has established KCNJ2 as a target of miR-1, and miR-1 is considered as a muscle-specific miRNA that plays an ... 2007) The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat. Med. 13: ...
https://rd.springer.com/article/10.2119%2Fmolmed.2011.00093
*  Tackling Skeletal Muscle Cells Epigenome in the Next-Generation Sequencing Era
"The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation," Nature Genetics, vol. 38, no. 2 ... "The polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation," Genes and ... M. Fulco, R. L. Schiltz, S. Iezzi et al., "Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox ... Moreover, the application of 4C/Hi-C-Seq technology and ChIA-PET in skeletal muscle cells that undergo differentiation will ...
https://www.hindawi.com/journals/ijg/2012/979168/
*  Resizing the Genomic Regulation of Restenosis | Circulation Research
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet. 2006; 38: 228-233. ... In addition, miR-21 inhibition resulted in decreased proliferation and increased death of vascular smooth muscle cells. They ... cultured rat vascular smooth muscle cells where in vitro dedifferentiation and proliferation of freshly isolated smooth muscle ... 7-9 There are also reports of miRNA regulation of skeletal muscle, but there are no studies on miRNA expression in ...
http://circres.ahajournals.org/content/100/11/1537.long
*  MicroRNA Regulation of Cardiovascular Development | Circulation Research
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet. 2006; 38: 228-233. ... yet complement each other by balancing the differentiation and proliferation of cardiac and skeletal muscle lineages. ... Furthermore, miR-133 targets SRF, which is important in muscle proliferation, differentiation and activation of the miR-1/miR- ... results in a muscle differentiation defect.47,54 In a subset of dmiR-1-null flies, muscle progenitors are arrested in a ...
http://circres.ahajournals.org/content/104/6/724
*  Deep sequencing and expression of microRNAs from early honeybee (Apis mellifera) embryos reveals a role in regulating early...
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet. 2006;38:228-233. doi: ... Sokol NS, Ambros V. Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval ... Chen Z, DiGeorge syndrome critical region 8(DGCR8) -mediated miRNA biogenesis is essential for vascular smooth muscle cell ... Kwon C, Han Z, Olson EN, Srivastava D. MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC3562263/?lang=en-ca
*  MicroRNA-196a/b Mitigate Renal Fibrosis by Targeting TGF-β Receptor 2 | American Society of Nephrology
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 38: 228-233, 2006pmid: ... also play an important role in modulating muscle proliferation and differentiation.38 Recent studies have also shown that ... 40 The miRNAs that predominantly express in cardiac and skeletal muscle tissue, such as miR-1 and miR-133, ... In the UUO model, miR-196a/b silenced TGF-β-Smad signaling, decreased the expression of collagen 1 and α-smooth muscle actin, ...
https://jasn.asnjournals.org/content/27/10/3006
*  miRNA Entry for MI0004890
"The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation.". Nat Genet 38 (2): 228-33. doi: ... "microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7.". J ... MiR-1 has key roles in the development and differentiation of smooth and skeletal muscles.[11][12][13] For example in the ... "MicroRNA-1 facilitates skeletal myogenic differentiation without affecting osteoblastic and adipogenic differentiation.". ...
http://mirbase.org/cgi-bin/mirna_entry.pl?acc=MI0004890
*  Microbiology Theses | Department of Microbiology | Southern Illinois University Carbondale
Understanding the role of JARID2 in skeletal muscle proliferation and differentiation, Pramish Mainali ...
http://opensiuc.lib.siu.edu/micro_theses/
*  JCI - Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration
The remarkable regeneration capability of skeletal muscle depends on coordinated proliferation and differentiation of satellite ... Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration. Liwei Xie, Amelia Yin, Anna S. ... inhibition of HIF2A accelerated muscle regeneration by increasing satellite cell proliferation and differentiation. ... Hypoxia profoundly affects the proliferation, differentiation, and self-renewal of cultured myoblasts. However, the ...
https://www.jci.org/articles/view/96208
*  Frontiers | The KCNE Tango - How KCNE1 Interacts with Kv7.1 | Pharmacology
Skeletal muscle Kv7 (KCNQ) channels in myoblast differentiation and proliferation. Biochem. Biophys. Res. Commun. 369, 1094- ... and pharmacological role of Kv7 potassium channels in skeletal muscle proliferation, differentiation, and survival after ... and smooth muscle (Figure 1; Table A1 in Appendix). Kv7.1 can assemble with different members of the KCNE family of regulatory ... KCNQ modulators reveal a key role for KCNQ potassium channels in regulating the tone of rat pulmonary artery smooth muscle. J. ...
https://www.frontiersin.org/articles/10.3389/fphar.2012.00142/full
*  Safety and Efficacy Study of IGF-1 in Duchenne Muscular Dystrophy - Full Text View - ClinicalTrials.gov
IGF-1 stimulates both the proliferation and differentiation of skeletal muscle cells and is thus important for muscle repair ... The purpose of this study is to determine whether IGF-1 therapy improves or preserves muscle function in Duchenne Muscular ... DMD is a progressive degenerative muscle disorder for which there is no current cure. Glucocorticoids (GC) are often used to ... DMD diagnosed with mutational testing and/or complete absence of dystrophin on muscle biopsy ...
https://clinicaltrials.gov/ct2/show/NCT01207908?term=increlex+dmd&
*  Embryonic anti-aging niche
microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. J ... The poor performance of stem cells in an aged organ, such as skeletal muscle, is caused by the changes in regulatory pathways ... The key age-specific changes in signal transduction are relatively well understood in skeletal muscle: old myofibers fail to up ... The role of p38b MAPK in age-related modulation of intestinal stem cell proliferation and differentiation in Drosophila. Aging ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC3156606/?lang=en-ca
*  Anti-miRNA oligonucleotides - Wikipedia
"The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation". Nature Genetics. 38 (2): 228-233 ... miRNA-1 plays a role in muscle differentiation between cardiac and skeletal muscle precursor cells. In development, if levels ... By creating AMOs for these known miRNAs involved in muscle generation, it is possible to track a miRNA's specific mechanisms ... By further understanding how certain miRNA sequences control the development of muscle, AMOs can be utilized to promote normal ...
https://en.wikipedia.org/wiki/Anti-miRNA_oligonucleotides
*  JCI - Welcome
The remarkable regeneration capability of skeletal muscle depends on coordinated proliferation and differentiation of satellite ... mice die perinatally from a skeletal muscle defect, Bin1-/- Dnm2+/- mice survived at least 18 months, and had normal muscle ... Regulation of skeletal muscle development and organization is a complex process that is not fully understood. Here, we focused ... Skeletal muscle is a key organ in energy homeostasis owing to its high requirement for nutrients. Heterotrimeric G proteins ...
https://www.jci.org/tags/30