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*  Mild hypoglycemia is independently associated with increased mortality in the critically ill | Critical Care | Full Text
Hypoglycemia was defined as BG , 70 mg/dL. Severe hypoglycemia was defined as BG , 40 mg/dL. Additional stratification included ... Finally, the association of hypoglycemia with mortality was cumulative to the associations of hyperglycemia and increased ... Intensive Care UnitBlood GlucoseHypoglycemiaIntensive Care Unit StaySevere Hypoglycemia ... Krinsley JS, Grover A: Severe hypoglycemia in critically ill patients: risk factors and outcomes. Crit Care Med 2007, 35: 2262- ...
https://ccforum.biomedcentral.com/articles/10.1186/cc10322
*  Diabetic ketoacidosis - Deranged Physiology
... and only mild hyperglycaemia. DKA comes up frequently in the CICM SAQs, but usually as an ABG interpretation exercise. This ... Severe hyperglycaemia. *Established renal failure. Precipitating factors for DKA. DKA requires a trigger. This takes the shape ... HONK presents with hyperglycaemia as the major feature. Discriminating Between HONK and DKA. Domain. Features suggestive of DKA ... Therapy of severe diabetic ketoacidosis. Zero-mortality under very-low-dose insulin application.' Diabetes care 22.5 (1999): ...
http://www.derangedphysiology.com/main/required-reading/endocrinology-metabolism-and-nutrition/Chapter%202.1.1/diabetic-ketoacidosis
*  Insulin Resistance Clinical Presentation: History, Physical Examination, Complications
Other patients present with cases of severe hyperglycemia that require large quantities of insulin (,200 units); these people ... Patients occasionally present with hypoglycemia. Agonist activity (hypoglycemia) or antagonist effect (insulin resistance) can ... Hypoglycemia results from interaction between insulinomimetic antibodies and the insulin receptor. Some patients have insulin- ... Managing Hyperglycemia in Type 2 Diabetes: Where's the Proof of the Pudding? ...
https://emedicine.medscape.com/article/122501-clinical
*  Hyperglycemia in diabetes - Diagnosis and treatment - Mayo Clinic
Hyperglycemia in diabetes can occur for many reasons. Know the causes, symptoms and treatments of high blood sugar and when to ... Check more frequently if you're ill or you're concerned about severe hyperglycemia or hypoglycemia. ... Emergency treatment for severe hyperglycemia. If you have signs and symptoms of diabetic ketoacidosis and hyperglycemic ... If you have any signs or symptoms of severe hyperglycemia - even if they're subtle - check your blood sugar level. If your ...
https://www.mayoclinic.org/diseases-conditions/hyperglycemia/diagnosis-treatment/drc-20373635
*  Self-Monitoring of Blood Glucose: The Basics | Clinical Diabetes
improving patients' recognition of hypoglycemia or severe hyperglycemia; and. *. enhancing patient education and patient ... Jungheim K, Koschinsky T: Risky delay of hypoglycemia detection by glucose monitoring at the arm. Diabetes Care 24:1303-1304, ... Although there has been concern that the accuracy of alternate site testing is inferior to detect hypoglycemia,4 the judicious ... Persistent fasting hyperglycemia, for example, might indicate excessive hepatic glucose output, and patients experiencing this ...
http://clinical.diabetesjournals.org/content/20/1/45.full
*  The Bidirectional Association Between Depression and Severe Hypoglycemic and Hyperglycemic Events in Type 1 Diabetes | Diabetes...
OBJECTIVE Severe hyperglycemia and hypoglycemia ("severe dysglycemia") are serious complications of type 1 diabetes (T1D). ... HRhyperglycemia 7.14 [95% CI 5.29, 9.63]; HRhypoglycemia 5.58 [95% CI 4.46, 6.99]) to 1 year (HRhyperglycemia 5.16 [95% CI 3.88 ... 6.88]; HRhypoglycemia 4.05 [95% CI 3.26, 5.04]) after depression diagnosis. In fully adjusted models specifying severe ... cases of hyperglycemia and hypoglycemia, respectively. In fully adjusted models, depression was strongly associated with a 2.5- ...
https://care.diabetesjournals.org/content/early/2017/12/14/dc17-1566
*  Kasia Lipska, MD, MHS, BS | Internal Medicine | Yale School of Medicine
McCoy RG, Herrin J, Lipska KJ, Shah ND: Recurrent hospitalizations for severe hypoglycemia and hyperglycemia among U.S. adults ... Lipska KJ, Warton EM, Huang ES, Moffet HH, Inzucchi SE, Krumholz HM, Karter AJ: HbA1c and risk of severe hypoglycemia in type 2 ... McCoy RG, Lipska KJ, Yao X, Ross JS, Montori VM, Shah ND: Intensive Treatment and Severe Hypoglycemia Among Adults With Type 2 ... High rates of severe hypoglycemia among African American patients with diabetes: the surveillance, prevention, and Management ...
https://medicine.yale.edu/intmed/people/kasia_lipska-2.profile
*  Plus it
All available history of severe hypoglycemia and hyperglycemia events prior to enrollment in the study was recorded. Most ... It should be noted, however, that the hypoglycemia exposure and the number of severe hypoglycemia events may have been too ... experienced an episode of severe hypoglycemia (defined as hypoglycemia with seizures or loss of consciousness). There were no ... Hyperglycemia not hypoglycemia alters neuronal dendrites and impairs spatial memory. Pediatr Diabetes 2008;9:531-539pmid: ...
http://care.diabetesjournals.org/content/37/2/332
*  Plus it
Regional brain volume differences associated with hyperglycemia and severe hypoglycemia in youth with type 1 diabetes. Diabetes ... Neuroanatomical variations in adult T1D also have been linked to severe hypoglycemia exposure, lifetime hemoglobin A1c (HbA1c ... Hyperglycemia-induced oxidative stress in diabetic complications. Histochem Cell Biol 2004;122:333-338pmid:15257460. ... Hypoglycaemia: brain neurochemistry and neuropathology. Baillieres Clin Endocrinol Metab 1993;7:611-625pmid:8379907. ...
http://diabetes.diabetesjournals.org/content/63/1/343
*  PPT - INTENSIVE INSULIN THERAPY PowerPoint presentation | free to download - id: 8346b-ZDc1Z
To detect or confirm hypoglycemia or severe hyperglycemia *To adjust treatment to the circumstances of daily life using an ... Hyperglycemia secondary to asymptomatic hypoglycemia (especially at night) *If the insulin is increased in evening, the problem ... post-prandial and fasting hyperglycemia. 7. CDA Guidelines (for glycemic control). Normal. Optimal. A1C level. (0.04-0.06). (lt ... Preventing Hypoglycemia*Test before driving and ideally 1 hour later (target over 5.5 mmol/L) ...
http://www.powershow.com/view1/8346b-ZDc1Z/INTENSIVE_INSULIN_THERAPY_powerpoint_ppt_presentation
*  Ghrelin Inhibits High Glucose-Induced PC12 Cell Apoptosis by Regulating TLR4/NF-κB Pathway | Springer for Research & Development
Regional brain volume differences associated with hyperglycemia and severe hypoglycemia in youth with type 1 diabetes. Diabetes ...
https://rd.springer.com/article/10.1007/s10753-013-9667-2
*  COMUNICADO: New Study With Victoza® (Liraglutide) Showed Improvements in Blood Glucose Control in Adults With Type 2 Diabetes...
... fast have an estimated 7.5-fold increased risk of severe hypoglycaemia and a five-fold increased risk of severe hyperglycaemia ... can affect blood glucose levels and result in severe hypoglycaemia and hyperglycaemia. To help minimise these risks, physicians ... Hypoglycaemia has primarily been observed when Victoza(R) is combined with a sulfonylurea or a basal insulin. ... Due to this glucose-dependent mechanism of action, Victoza(R) is associated with a low rate of hypoglycaemia.[*],[6] In ...
http://www.europapress.es/comunicados/internacional-00907/noticia-comunicado-new-study-with-victoza-liraglutide-showed-improvements-in-blood-glucose-control-in-adults-with-type-diabetes-who-fa-20150606160109.html
*  Closed-loop insulin control for T2DM is feasible in hospital setting | The Hospitalist
None of the patients suffered from severe hypoglycemia or clinically significant hyperglycemia with ketonemia. ... However, "our results suggest this new technology might be another approach to manage in-patient hypoglycemia in a safe and ... There were 18 incidents of clinically significant hyperglycemia events (capillary glucose levels of more than 360 mg/dL) in the ... The researchers didn't find a statistically significant difference between the groups in duration of hypoglycemia or amount of ...
https://www.the-hospitalist.org/hospitalist/article/170104/diabetes/closed-loop-insulin-control-t2dm-feasible-hospital-setting
*  Faculty Details | Psychiatry | Washington University
1) effects of severe hypoglycemia and hyperglycemia on the brain in children and adults with type 1 diabetes mellitus.. 2) ...
http://psychiatry.wustl.edu/Faculty/FacultyDetails?ID=568
*  Chronic Care Center - Prevention Program
Management of acute complications: hypoglycemia or hyperglycemia especially in severe cases.. How to accept the disease and ... About acute complications of Diabetes: symptoms of hypoglycemia and hyperglycemia, how to prevent it and appropriate actions to ... Hyperglycemia: (BG,180mg/dl), due to untreated Diabetes, excessive food intake, insufficient medications, illness and stress. ... Hypoglycemia (BG,60mg/dl), due to inadequate food intake, excessive insulin or increased physical activity. ...
http://chroniccare.org.lb/Prevention
*  Byetta Pancreatic Cancer Lawsuit News & Legal Information FAQ
Since Byetta was first introduced on the market, it has been linked to cases of acute pancreatitis, hyperglycemia, hypoglycemia ... Acute, hemorrhagic and necrotizing pancreatitis are severe forms of pancreatitis. Hemorrhagic pancreatitis results in severe ... Symptoms of pancreatitis include severe abdominal pain that may radiate to the back. This pain may or may not be accompanied by ... and severe allergies. It has also been linked to altered kidney function and renal kidney failure. According to the US Food and ...
https://www.lawyersandsettlements.com/faq/byetta.html
*  A Case Oriented Approach to Liver Laboratory Profiling in Dogs and Cats - WSAVA2008 - VIN
Chronic severe liver disease can cause hypoglycemia or hyperglycemia. This is a reflection of reduced glycogen storage capacity ... The presence of hypoglycemia in cases of obvious liver disease is therefore a poor prognostic sign. Hyperglycemia in liver ... The majority of the plasma proteins are produced in the liver and severe liver disease may be a cause of hypoproteinemia due to ... Positive urine bilirubin tests in cats are only obtained in the most severe cases of liver disease, usually after clinical ...
https://www.vin.com/apputil/content/defaultadv1.aspx?pId=11268&meta=Generic&catId=32735&id=3866598&ind=226&objTypeID=17
*  AskNadia: Convicted of a DUI Because of My DKA | Diabetes Health
Every few years there are stories in the media about people with diabetes experiencing severe hypoglycemia or hyperglycemia who ... disability Diabetes Health Diabetes Health Magazine diabetes inspiration Diet Exercise Health Healthy Living Hypoglycemia ...
https://www.diabeteshealth.com/asknadia-convicted-dui-dka/
*  Clinical Effects and Safety of Direct-Acting Insulin Analogs in Patients with Type 1 Diabetes: A Nation-Wide Observational...
Severe hypoglycemia was more common among older patients, while severe hypoglycemia and hyperglycemia were more common among ... and severe hyperglycemia was less common among patients aged 65 years or older, while severe hypoglycemia and hyperglycemia ... while Cox regression suggested lower rates of hypoglycemia among glulisine users. Severe hypoglycemia was more common, ... There were no significant differences between groups regarding hyperglycemia requiring hospitalization, CVE, or mortality, ...
https://www.springermedizin.de/clinical-effects-and-safety-of-direct-acting-insulin-analogs-in-/10581144
*  Patent US7790690 - Glucose sensitive regulator of insulin transcription - Google Patents
A method of modulating hyperglycemia, while avoiding severe hypoglycemia, in a subject by administering an effective amount of ... Severe hypoglycemia, arbitrarily defined as ≧50 mg/dl, was detected 8 times (4.30%), with a nadir of 29 mg/dl. No animal died ... they observed severe hypoglycemia (≦58/mg/dl) in 40% of fasting blood glucose values (Reference 50). By contrast, we observed ... and the spontaneous hyperglycemia in DP BB Wor rats without producing lethal hypoglycemia. Additional work is contemplated to ...
http://www.google.com/patents/US7790690?dq=6825444
*  HbA1c overtesting and overtreatment among US adults with controlled type 2 diabetes, 2001-13: observational population based...
... had no history of severe hypoglycemia or hyperglycemia, and were not pregnant. HbA1c testing frequency was measured within 24 ... Severe hypoglycemia and risks of vascular events and death. N Engl J Med2010;363:1410-8. ... Increased mortality of patients with diabetes reporting severe hypoglycemia. Diabetes Care2012;35:1897-901. ... The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological ...
https://www.bmj.com/content/351/bmj.h6138
*  Type Ii Diabetes Overview - My Diabetes Blog
Among the risks are severe hypoglycemia, hyperglycemia, diabetic ketoacidosis, dehydration and thrombosis. Even though the ... with hyperglycemia or hypoglycemia who not test his blood sugar can suffer from a new number of serious problem. ... But the impact of this disease to be able to human life is also severe which means you need to give it the same amount of ...
http://creekstonerealty.org/type-ii-diabetes-overview/
*  Continuous Glucose Monitoring in Very Preterm Infants: A Randomized Controlled Trial | Articles | Pediatrics
... and severe (P = .007) hypoglycemia and in severe hyperglycemia (P = .04) compared with the blinded CGM group. Use of CGM also ... and severe (,47 mg/dL) hypoglycemia; percentage of time in mild (145-180 mg/dL) and severe (,180 mg/dL) hyperglycemia; and ... Strategies based on insulin titration have been unsuccessful in achieving euglycemia in absence of an increase in hypoglycemia ... CONCLUSIONS: CGM-guided glucose titration can successfully increase the time spent in euglycemic range, reduce hypoglycemia, ...
https://pediatrics.aappublications.org/content/140/4/e20171162.abstract
*  Endocrinology Outcomes | Nemours Children's Health System
serious short-term problems such as severe hypoglycemia (low blood sugars), hyperglycemia (high blood sugars) or DKA ... Ketoacidosis can become a severe, life-threatening condition that requires immediate treatment. ...
https://www.nemours.org/about/why/outcomes/endocrinology.html
*  ADA/JDRF Type 1 Diabetes Sourcebook, Excerpt #13: Setting Treatment Targets, Part 2 of 2
... the degree of relaxation of glucose targets is that which eliminates hypoglycemia without causing severe hyperglycemia or ... Severe hypoglycemia. Higher targets are reasonable in patients with severe hypoglycemia or hypoglycemia unawareness in order to ... 66 This is of particular relevance in patients with prior episodes of severe hypoglycemia or with hypoglycemia unawareness. ... Effects of severe hypoglycemia on cognitive function in children with T1D stratified by age in order to more closely establish ...
http://www.diabetesincontrol.com/adajdrf-type-1-diabetes-sourcebook-excerpt-13-setting-treatment-targets-part-2-of-2/