Metachromatic leukodystrophy - Wikipedia
Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents | Nature...
This could have been caused by accumulation of PSAP and saposins in DA neurons over time, Moreover, we believe that part of ... PSAP is cleaved to saposins in the lysosome, which, in turn, regulate a subset of lysosomal sphingolipid related hydrolases5. ... Magenta arrows are metabolic pathways modulated by saposins. L Graph showing gangliosides in DRN of two genotypes. Students t- ... It should be noted that the cleavage of PSAP into saposins varies between cell types and more studies are needed to ...
PSAP gene: MedlinePlus Genetics
Functional study of saposin-like proteins in Arabidopsis thaliana
FTD Fluid Markers for Degeneration: Check. For Pathology: Not Yet. | ALZFORUM
Neuronal Ceroid Lipofuscinoses: Background, Etiology, Epidemiology
SMART: SapB domain annotation
The mammalian saposins are synthesized as a single precursor molecule (prosaposin) which contains two saposin A-type domains in ... The saposin B-type domain is a ~80 amino acid domain present in saposins and related proteins that interact with lipids. The ... the extremities that are removed in the activation reaction, and four saposin B-type domains yielding the active saposins A, B ... domain is named after the small lysosomal proteins, saposins, which serve as sphingolipid hydrolase activator proteins in ...
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PSAP Antibody | Affinity Biosciences LTD|亲科生物官网
Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with ... Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, ... This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each ... Saposins; Sgp1; Sphingolipid activator protein 1; Sphingolipid activator protein 2; Sulfated glycoprotein 1; Sulfatide/GM1 ...
Katsumi Mominoki - Research output - Okayama University
Shigemoto, K., Kubo, S., Jie, C., Hato, N., Abe, Y., Ueda, N., Kobayashi, N., Kameda, K., Mominoki, K., Miyazawa, A., Ishigami, A., Matsuda, S. & Maruyama, N., Jun 2008, Myasthenia Gravis and Related Disorders 11th International Conference. Blackwell Publishing Inc., p. 93-98 6 p. (Annals of the New York Academy of Sciences; vol. 1132).. Research output: Chapter in Book/Report/Conference proceeding › Conference contribution ...
Salam Al-Karadaghi - Research output - Lund University
Aevarsson, A., Kaczorowska, A-K., Adalsteinsson, B. T., Ahlqvist, J., Al-Karadaghi, S., Altenbuchner, J., Arsin, H., Átlasson, Ú. Á., Brandt, D., Cichowicz-Cieślak, M., Cornish, K. A. S., Courtin, J., Dabrowski, S., Dahle, H., Djeffane, S., Dorawa, S., Dusaucy, J., Enault, F., Fedøy, A-E., Freitag-Pohl, S., & 32 othersFridjonsson, O. H., Galiez, C., Glomsaker, E., Guérin, M., Gundesø, S. E., Gudmundsdóttir, E. E., Gudmundsson, H., Håkansson, M., Henke, C., Helleux, A., Henriksen, J. R., Hjörleifdóttir, S., Hreggvidsson, G. O., Jasilionis, A., Jochheim, A., Jónsdóttir, I., Jónsdóttir, L. B., Jurczak-Kurek, A., Kaczorowski, T., Kalinowski, J., Kozlowski, L. P., Krupovic, M., Kwiatkowska-Semrau, K., Lanes, O., Linares-Pastén, J., Karlsson, E. N., Skírnisdóttir, S., Svensson, A., Walse, B., Welin, M., Zhang, R. & Virus-X, 2021 Jun 24, In: FEMS Microbiology Letters. 368, 12, 16 p., fnab067.. Research output: Contribution to journal › Review article › peer-review ...
Pesquisa | Portal Regional da BVS
Both saposins and PS are widely contained in various tissues. The brain, skeletal muscle, and heart cells predominantly contain ... Neurotrophic factor prosaposin (PS) is a precursor for saposins A, B, C, and D, which are activators for specific sphingolipid ... Prosaposin (PSAP), a highly conserved glycoprotein, is a precursor of saposins A-D. Accumulating evidence suggests that PSAP is ... unprocessed PS rather than saposins. PS and PS-derived peptides stimulate neuritogenesis and increase choline acetyltransferase ...
ProRule PRU00415
Synthese von Glycoformen lysosomaler Sphingolipidaktivatorproteine - EPub Bayreuth
DeCS 2016 - June 12, 2016 version
DeCS 2019 - June 12, 2019 version
DeCS 2018 - July 31, 2018 version
DeCS 2017 - July 04, 2017 version
DeCS 2020 - June 23, 2020 version
Browse by Research Team - MDC Repository
Anti-Cheat Bypasser | VAC Bypass, Silent Aim, Mods - AGCTecnologías
Distinctive structural features are shared by human, lapine, and murine acyloxyacyl hydrolases<...
The large subunit contains the active site serine, while the smaller subunit has striking sequence similarity to the saposins, ... The large subunit contains the active site serine, while the smaller subunit has striking sequence similarity to the saposins, ... The large subunit contains the active site serine, while the smaller subunit has striking sequence similarity to the saposins, ... The large subunit contains the active site serine, while the smaller subunit has striking sequence similarity to the saposins, ...