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*  Long noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes. - Nuffield Department of...
This dearth of information is partially attributable to a lack of established non-protein-coding RNA (ncRNA) orthologs among ... study of four highly conserved and brain-expressed transcripts selected from a list of mouse long intergenic noncoding RNA ( ... their pattern of brain expression during embryonic and early postnatal stages together indicate that these are functional RNA ... RNA, Untranslated, Sequence Homology, Nucleic Acid, Vertebrates ... Long noncoding RNA genes: conservation of sequence and brain ...
https://www.ndcn.ox.ac.uk/publications/106551
*  IJMS | Free Full-Text | Noncoding RNA in Oncogenesis: A New Era of Identifying Key Players | HTML
At the end, we will also discuss recently unraveled activities of circular RNAs (circRNAs). ... New discoveries and accelerating progresses in the field of noncoding RNAs (ncRNAs) continuously challenges our deep-rooted ... A SNP in a let-7 microRNA complementary site in the KRAS 3′ untranslated region increases non-small cell lung cancer risk. ... 3. Long Noncoding RNA. Long noncoding RNAs (lncRNAs) were previously defined as RNA molecules longer than 200 nucleotides that ...
http://mdpi.com/1422-0067/14/9/18319/htm
*  "A sequence-specific RNA binding complex expressed in murine germ cells" by H G. Davies, F Giorgini et al.
Translational repression of the protamine 1, Prm1, mRNA is controlled by sequences in its 3'-untranslated region (UTR). In this ... RNA-Messenger, RNA-Binding-Proteins, Ribonucleoproteins, Spermatogenesis, Testis, Yeasts ... Davies, H G.; Giorgini, F; Fajardo, M A.; and Braun, R E., "A sequence-specific RNA binding complex expressed in murine germ ... A sequence-specific RNA binding complex expressed in murine germ cells contains MSY2 and MSY4. ...
https://mouseion.jax.org/stfb2000_2009/854/
*  Ching-Yi Chen, PhD | Nutrition & Obesity Research Center
Gherzi, R., Lee, K.-Y., Briata, P., Wegmüller, D., Moroni, C., Karin, M. and Chen, C.Y. (2004). A KH domain RNA binding protein ... Many of these transcripts contain cis-acting instability elements within their 3' untranslated regions that are believed to ... The RNA-binding protein KSRP promotes decay of -catenin mRNA and is inactivated by PI3K-AKT signaling. PLos Biol. 5, 82-95. ... AMD is regulated by RNA-binding proteins. A number of proteins have been described to bind AREs and are collectively called ARE ...
http://www.norc.uab.edu/people/cchen
*  RNA, Untranslated | ISHAR Online
It is now evident that nonprotein coding RNA (ncRNA) plays a critical role in regulating the timing and rate of protein ... In the decade following the publication of the Human Genome, noncoding RNAs (ncRNAs) have reshaped our understanding of the ... Since small non-coding RNAs (including microRNAs) are implicated in the regulation of gene expression, we hypothesised that ... In this review, we discuss several examples of known RNA mechanisms for the regulation of protein synthesis. ...
http://isharonline.org/tags/rna-untranslated
*  Aberrant regulation of messenger RNA 3′-untranslated region in human cancer - IOS Press
... untranslated region (3′UTR) is emerging as critically important in regulating gene expression at posttranscriptional levels. ... Abstract: The messenger RNA 3′-untranslated region (3′UTR) is emerging as critically important in regulating gene expression at ... Aberrant regulation of messenger RNA 3′-untranslated region in human cancer Article type: Research Article ... Keywords: Post-transcriptional gene regulation, RNA-binding proteins, non-coding RNAs, miRNAs, AU-rich elements (ARE), ...
https://content.iospress.com/articles/analytical-cellular-pathology/clo357
*  A 3' untranslated region variant in FMR1 eliminates neuronal activity-dependent translation of FMRP by disrupting binding of...
Mobility-shift assays using a control RNA detected an RNA-protein interaction that is lost with the patient RNA, and HuR was ... untranslated region variant in FMR1 eliminates neuronal activity-dependent translation of FMRP by disrupting binding of the RNA ... untranslated region variant in FMR1 eliminates neuronal activity-dependent translation of FMRP by disrupting binding of the RNA ... untranslated region variant in FMR1 eliminates neuronal activity-dependent translation of FMRP by disrupting binding of the RNA ...
https://www.ncbi.nlm.nih.gov/pubmed/26554012
*  Small RNAs as guardians of the genome. - PubMed - NCBI
RNA, Untranslated/genetics*. *RNA, Untranslated/metabolism*. Substance. *RNA, Untranslated. Grant support. *P01 CA013106/CA/NCI ... Ping-pong and RNA-dependent RNA polymerase (RDRP) cycles amplify small RNA populations against target molecules.. (A) Maternal ... B) Transcripts targeted by small RNAs are cleaved by the RNA-induced silencing complex (RISC). RDRP subsequently loads and ... The new dsRNA molecule is recognized and processed into small RNAs by a Dicer protein, followed by loading of single-stranded ...
https://www.ncbi.nlm.nih.gov/pubmed/19239887
*  A new class of non-coding RNAs associated with 3' untranslated regions of mRNAs | Archivio Istituzionale della Ricerca
A new class of non-coding RNAs associated with 3' untranslated regions of mRNAs. ... A new class of non-coding RNAs associated with 3' untranslated regions of mRNAs ... Moreover, while small regulatory RNAs can be relatively easily classified on the basis of their length, secondary structure, ... The importance of non-coding RNAs (ncRNAs) in controlling gene expression is becoming increasingly evident. However, except for ...
https://air.unimi.it/handle/2434/54671
*  IGF2 | Cancer Genetics Web
The oncofetal RNA-binding protein IGF2BP1 (IGF2 mRNA binding protein 1) is overexpressed in a subset of cancers and promotes ... The small-interfering RNA knockdown of Atg7, and treatment with 3-methyladenine, restores bort sensitivity in bort-resistant ... In a separate in vitro study, RNA interference method was applied for knockdown of IMP3 gene in human LAC cell lines. Invasive ... ETV6/RUNX1 transcript is a target of RNA-binding protein IGF2BP1 in t(12;21)(p13;q22)-positive acute lymphoblastic leukemia.. ...
http://www.cancerindex.org/geneweb/IGF2.htm
*  Computing for Comparative Microbial Genomics | SpringerLink
Transcriptomics: Translated and Untranslated RNA David W. Ussery, Trudy M. Wassenaar, Stefano Borini ... Chromosome DNA Metagenomics RNA bioinformatics databases evolution gene expression genome heat map metagenomes microbiology ... Familiarizes readers with genome sequences, RNA sequences (transcriptomics), proteomics and regulation of gene expression ... RNA, and protein, in terms of structural and functional analysis. ...
https://link.springer.com/book/10.1007%2F978-1-84800-255-5
*  Improved Annotation of 3′ Untranslated Regions and Complex Loci by Combination of Strand-Specific Direct RNA Sequencing, RNA...
Until recently, the genome-wide annotation of 3' untranslated regions received less attention than coding regions and the ... Direct RNA Sequencing technology from Helicos Biosciences which locates 3' polyadenylation sites to within +/- 2 nt, were ... clearer interpretation of small RNA expression and (4) identification of novel genes. While the specific examples displayed ... combined with archival EST and RNA-Seq data. Nine examples are illustrated where this combination of data allowed: (1) gene and ...
https://www.semanticscholar.org/paper/Improved-Annotation-of-3%E2%80%B2-Untranslated-Regions-and-Schurch-Cole/7521ba90a496b3a37c277d1189db03c32421ab74
*  Model equations: protein-protein interactions.The mod | Open-i
Model equations: protein-protein interactions.The model equations for coactivation (Equation 5), short-range quenching (Equation 6), direct repression (Equati
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3585115_pgen.1003243.g003&req=4
*  Effects of intra-CA3 injection of the NMDA receptor ant | Open-i
RNA, Untranslated/genetics. *Receptors, Leptin/genetics/metabolism. *Synapses/drug effects. *Wakefulness. Related in: ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4362753_nihms-597314-f0002&req=4
*  Toxin-antitoxin system - Wikipedia
subscription required) Silvaggi JM, Perkins JB, Losick R (October 2005). "Small Untranslated RNA Antitoxin in Bacillus subtilis ... The toxic activity of ToxN is inhibited by ToxI RNA, an RNA with 5.5 direct repeats of a 36 nucleotide motif ( ... Christensen-Dalsgaard M, Overgaard M, Winther KS, Gerdes K (2008). "RNA decay by messenger RNA interferases". Meth. Enzymol. ... Greenfield TJ, Ehli E, Kirshenmann T, Franch T, Gerdes K, Weaver KE (August 2000). "The antisense RNA of the par locus of pAD1 ...
https://en.wikipedia.org/wiki/Toxin-antitoxin_system
*  TxpA-RatA toxin-antitoxin system - Wikipedia
Toxin-antitoxin system Hok/sok system RdlD RNA Silvaggi JM, Perkins JB, Losick R (October 2005). "Small untranslated RNA ... It consists of a non-coding 222nt sRNA called RatA (RNA anti-toxin A) and a protein toxin named TxpA (Toxic protein A). RatA ... Lee JM, Zhang S, Saha S, Santa Anna S, Jiang C, Perkins J (December 2001). "RNA expression analysis using an antisense Bacillus ... Fozo EM, Hemm MR, Storz G (December 2008). "Small toxic proteins and the antisense RNAs that repress them". Microbiol. Mol. ...
https://en.wikipedia.org/wiki/TxpA-RatA_toxin-antitoxin_system
*  Department of Biological Sciences - University at Albany - SUNY
Single molecule study of alternative folding of a retroviral untranslated RNA. Gregory Lnenicka. Current projects include the ... RNA target development and validation for drug-resistant Gram positive pathogens. How a Cdka11 mutation is related to an ... One research project relates to intron dispersal under cell stress, and to the structure and function of a catalytic RNA that ... We want to define a dynamic RNA regulatory network for germline development by determining structures of 3'UTRs in vivo and how ...
https://www.albany.edu/biology/graduate_programs/doctoral/general_info2017.shtml
*  Protocols and Video Articles Authored by Richard Losick (Translated to Japanese)
The antitoxin, which is called RatA (for RNA antitoxin A), is a small (222 nucleotides), untranslated RNA that blocks the ... Small Untranslated RNA Antitoxin in Bacillus Subtilis Journal of Bacteriology. Oct, 2005 , Pubmed ID: 16166525 Toxin-antitoxin ... The ability of RNA polymerase holoenzyme to synthesize rRNA in vitro is not lost after extensive purification. RNA polymerase ... Core RNA polymerase purified from dormant spores has a subunit structure indistinguishable from vegetative core enzyme.RNA ...
https://www.jove.com/author/Richard_Losick?language=Japanese
*  basal cell carcinoma of external ear 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
RNA, Untranslated. Receptors, Cell Surface / metabolism. Receptors, G-Protein-Coupled / genetics. Receptors, G-Protein-Coupled ... RNA, Untranslated; 0 / Receptors, Cell Surface; 0 / Receptors, G-Protein-Coupled; 0 / Shh protein, mouse; 0 / Smo protein, ... Chemical-registry-number] 0 / Bacterial Proteins; 0 / Cadherins; 0 / Gt(ROSA)26Sor non-coding RNA, mouse; 0 / Hedgehog Proteins ...
http://www.bmlsearch.com/?kwr=basal+cell+carcinoma+of+external+ear+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  Toxins | Free Full-Text | Toxin-Antitoxin Systems of Staphylococcus aureus | HTML
TA systems controlled by interaction between toxin protein and antitoxin RNA have been identified in S. aureus in silico, but ... The SprA1/SprA1AS and SprF1/SprG1 systems are post-transcriptionally regulated by RNA antitoxins and encode small membrane ... Dependent on the chemical nature of the antitoxins (protein or RNA) and how they control the activity of the toxin, TA systems ... Silvaggi, J.M.; Perkins, J.B.; Losick, R. Small untranslated RNA antitoxin in Bacillus subtilis. J. Bacteriol. 2005, 187, 6641- ...
https://www.mdpi.com/2072-6651/8/5/140/htm
*  The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization.
While it is established that the 5' region of Xist RNA, ... in female mammals depends on the noncoding RNA X inactivation ... RNA Folding*. RNA, Long Noncoding. RNA, Untranslated / chemistry*, metabolism. Repetitive Sequences, Nucleic Acid*. ... 0/RNA, Long Noncoding; 0/RNA, Untranslated; 0/XIST non-coding RNA ... Title: RNA (New York, N.Y.) Volume: 17 ISSN: 1469-9001 ISO Abbreviation: RNA Publication Date: 2011 Nov ...
http://www.biomedsearch.com/nih/Xist-RNA-repeat-comprises-novel/21947263.html
*  Thomas Rando, MD, PhD | Stanford Medicine Profiles
TUMOR SUPPRESSION BY RNA FROM THE 3' UNTRANSLATED REGION OF ALPHA-TROPOMYOSIN CELL Rastinejad, F., Conboy, M. J., Rando, T. A ... We show that constitutive expression of RNA from 0.2 kb of the alpha-tropomyosin (Tm) 3' untranslated region (UTR), but not ... We conclude that untranslated RNAs can function as regulators (riboregulators) that suppress tumor formation. ... Northwestern blotting revealed that NF90 is the principal and specific p21WAF1/CIP1 and MyoD 3'-untranslated region RNA-binding ...
https://med.stanford.edu/profiles/thomas-rando
*  tsRNA signatures in cancer | PNAS
Small, noncoding RNAs are short untranslated RNA molecules, some of which have been associated with cancer development. ... 2010) Human tRNA-derived small RNAs in the global regulation of RNA silencing. RNA 16:673-695. ... 2015) SHOT-RNAs: A novel class of tRNA-derived functional RNAs expressed in hormone-dependent cancers. Mol Cell Oncol 3: ... RNA was extracted using the standard TRIzol method (Invitrogen), and RNA quality was assayed using an Agilent 2100 Bioanalyzer. ...
https://www.pnas.org/content/114/30/8071.full
*  The Dark Matter of the Genome
The rest of the genome consists of non-coding RNA, untranslated regions, splice sites and transposable elements. ... The rest of the genome consists of non-coding RNA, untranslated regions, splice sites and transposable elements. Most of the ... Non-coding RNAs. Non-coding RNAs or ncRNAs are transcripts which do not code for proteins. Micro RNAs (miRNAs) are small ncRNA ... Long non-coding RNA. More than 50,000 non-coding RNAs are transcribed in the human genome which are not translated in to ...
https://www.news-medical.net/life-sciences/The-Dark-Matter-of-the-Genome.aspx