"Small untranslated RNA antitoxin in Bacillus subtilis". J. Bacteriol. 187 (19): 6641-6650. doi:10.1128/JB.187.19.6641-6650.2005 ... Page for RNA anti-toxin A at Rfam (Antisense RNA, RNA antitoxins). ... Fozo EM, Hemm MR, Storz G (December 2008). "Small toxic proteins and the antisense RNAs that repress them". Microbiol. Mol. ... It consists of a non-coding 222nt sRNA called RatA (RNA anti-toxin A) and a protein toxin named TxpA (Toxic protein A). RatA ...

RNA, Bacterial / physiology * RNA, Small Untranslated / genetics* * RNA, Small Untranslated / metabolism * RNA, Small ... Small regulatory RNAs in Pseudomonas aeruginosa RNA Biol. 2012 Apr;9(4):364-71. doi: 10.4161/rna.19231. Epub 2012 Feb 16. ... Adaptive responses to various environmental stresses and stimuli are often regulated by small regulatory RNAs (sRNA). In this ... DOI: 10.4161/rna.19231 Abstract The opportunistic human pathogen Pseudomonas aeruginosa is frequently associated with ...

RNA, Bacterial / metabolism* * RNA, Small Untranslated / metabolism* Substances * Escherichia coli Proteins * LEE protein, E ... Small RNA Esr41 inversely regulates expression of LEE and flagellar genes in enterohaemorrhagic Escherichia coli Microbiology ( ... We report here that a small regulatory RNA (sRNA), Esr41, mediates LEE repression and flagellar gene activation. Multiple ... Esr41-mediated ler and pch repression was not observed in cells lacking hfq, which encodes an RNA-binding protein essential for ...

The partial 5′ untranslated region (UTR) was 109 nt and the partial 3′ UTR was 191 nt. Potential RNA splicing signals in AMDV ... Two small middle ORFs (67 and 75 aa long) with putative alternative start codons were detected in the 448-bp region between the ... Rapid identification of known and new RNA viruses from animal tissues. PLoS Pathog. 2008;4:e1000163. DOIPubMedGoogle Scholar ... Putative NS and VP1/VP2 gene RNA splicing sites were detected in the GFADV genome, which suggests the expression of different ...

As an alternative we will use Ion torrent to sequence these small RNA-ligation RT-PCR amplicons. ... A. RNA ligation is used to link the 5 and 3 termini, which circularizes the genomic RNAs, then we use RT-PCR to amplify the ... Role of the Untranslated Regions of the Influenza a Virus Replication and Vaccines. ... For these samples we will only need to add RNA ligation RT-PCR data to complete the UTRs. ...

RNAs, and the centromere repeat associated short interacting (crasi) RNAs in the tammar. We examined each of these small RNA ... we have characterized the major classes of small RNAs, micro (mi) RNAs, piwi interacting (pi) ... These small RNAs are derived largely from centromere-enriched retroelements, including a novel SINE. This study encompasses the ... A survey of the tammar gonadal piRNAs shows that these small RNAs are enriched in retroelements and carry members from both ...

miR, microRNA; oe, overexpression vector; lncRNA, long non-coding RNA; si, small, interfering RNA; NC, negative control. ... miR, microRNA; NC, negative control; lncRNA, long non-coding RNA; WT, wild type; MUT, mutant; UT3, untranslated region. ... Fang J, Sun CC and Gong C: Long noncoding RNA XIST acts as an oncogene in non-small cell lung cancer by epigenetically ... Small interfering RNA (si)PIK3CA significantly decreased PIK3CA expression, indicating the transfection was successful (Fig. 5A ...

... we designed eight small interfering RNAs (siRNAs) targeting the highly conserved 5′-untranslated region (5′-UTR) of SARS-CoV-2 ... A promising strategy to specifically target viral infections is to suppress viral replication through RNA interference (RNAi). ... which is present in the genomic as well as in all subgenomic RNAs. In assays with infectious SARS-CoV-2, it reduced replication ... Bantounas, I.; A Phylactou, L.; Uney, J.B. RNA interference and the use of small interfering RNA to study gene function in ...

RNA-protein or RNA-RNA interactions by protein pull-down or affinity pull-down methods are useful methods for the study of RNA ... Specific tertiary structure types are observed for transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), ... mRNAs can also adopt complex tertiary structures, especially in the untranslated terminal regions (UTRs). ... a variety of RNA methods have been developed for the study of RNA-DNA, RNA-RNA, and RNA-protein interactions including RNA ...

... long noncoding RNAs (lincRNAs), and small noncoding RNAs (snRNAs). Notably, the enrichment for functionally annotated genomic ... untranslated regions (UTRs), 3′ UTRs, promoters, introns, long intergenic noncoding RNAs (lincRNA), short noncoding RNAs ( ... B) FitCons scores increase with RNA-seq intensity. 0: no RNA-seq reads; 1-3: weak to strong RNA-seq signal (see Methods). (C) ... Application to RNA-seq data. We applied the procedure described above separately to the RNA-seq data of each of the three cell ...

... downregulation by antisense morpholino and/or transgenic expression of miR-sponge RNA induced significant impairment of both ... untranslated region. In addition, as this small RNA is associated with a number of neuronal biological mechanisms such as ... Stefani G, Slack FJ . Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol 2008; 9: 219-230. ... Small non-coding RNAs in particular have emerged as potential candidates as they can exert a broad influence on functional ...

GAPDH and U6 small nuclear RNA (U6 snRNA) were used as internal references for mRNA and miRNA, respectively. Relative ... untranslated region (UTR). Recently, miRNAs were also found to be associated with myocardial I/R injury (6,7). miR-132 was ... MicroRNAs (miRNAs) are small endogenous RNAs that are associated with tumourigenesis, cell proliferation and apoptosis (4,5). ... Total RNA was extracted from myocardial tissues or H9C2 cells using TRIzol reagent (Invitrogen; Thermo Fisher Scientific, Inc ...

... are small non-coding RNAs 18-24 nucleotides in length that regulate gene expression by targeting the 3 untranslated region of ... BM is the main risk factor for Barretts adenocarcinoma (BAc). MicroRNAs (miRNAs) are a class of small non-coding RNAs that ... Altered expression of circular RNAs (circRNAs) has previously been investigated in breast cancer. However, little is known ... Altered expression of circular RNAs (circRNAs) has previously been investigated in breast cancer. However, little is known ...

P. Landgraf, M. Rusu, R. Sheridan et al., "A mammalian microRNA expression atlas based on small RNA library sequencing," Cell, ... a) Sequence of human miR-339 and the predicted binding sites with miR-339 within Sirt2 untranslated region (3′-UTR) from ... Z. Mourelatos, "Small RNAs: the seeds of silence," Nature, vol. 455, no. 7209, pp. 44-45, 2008. ... MicroRNAs (miRNAs) is a large family of endogenous, small noncoding RNAs with 20-25 nucleotides that have emerged as key ...

miRNAs are small non-coding RNAs of 20-22 nucleotides that, through imperfect pairing, bind to the 3′ untranslated regions of ... Transcriptional control of the endogenous MYC protooncogene by antisense RNA. Proc Natl Acad Sci U S A 1987;84:7363-7. ... A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell 2010;142:409-19. ... These RNAs are transcribed by polymerase II but do not encode proteins. The LincRNAs serve to suppress transcription by ...

... untranslated m-RNA sequence that is expressed by many small-cell lung cancer cells and by all neurons. ... This syndrome is associated with malignancy 50-60% of the time, typically small-cell lung cancer, but also non-small-cell lung ... Early-Stage and Locally Advanced Non-Small Cell Lung Cancer Management 1.25 CME / CE / ABIM MOC Credits Experts And Viewpoints ... It has long been known that patients with small-cell lung cancer [2] develop neurological signs and symptoms with increased ...

Currently, an increasing number of studies have indicated that miRNAs and small noncoding RNA molecules have great potential ... untranslated region of the target mRNAs and act as oncogenes or tumor suppressors to regulate cell signaling pathways, ... Cells were lysed with TRIzol reagent (catalog number: T9424; Sigma-Aldrich) to extract total RNA. One microgram of total RNA ... H. Bjeije, B. M. Soltani, M. Behmanesh, and M. R. Zali, "YWHAE long non-coding RNA competes with miR-323a-3p and miR-532-5p ...

... untranslated region, determining the fate of mRNAs in eukaryotic cells. Although a small number of 3 regulatory regions have ... untranslated region, determining the fate of mRNAs in eukaryotic cells. Although a small number of 3 regulatory regions have ... In addition, after transcription, a wide array of RNA-binding proteins interacts with cis-acting elements located mainly in the ... In addition, after transcription, a wide array of RNA-binding proteins interacts with cis-acting elements located mainly in the ...

... long intergenic RNA, small nucleolar RNA, natural antisense transcript, small nuclear RNA, and small RNA using published ... Analysis of the splicing events and RNA-Seq based expression profiles revealed the landscapes of gene structures, untranslated ... the various classes of non-coding RNA, and small RNA. The TAIR10 annotation update had a profound impact on Arabidopsis ... Altogether, we identified 635 novel protein-coding genes, 508 novel transcribed regions, 5178 non-coding RNAs, and 35 846 small ...

Noncoding RNA sequences, including long noncoding RNAs, small nucleolar RNAs, and untranslated mRNA regions, accomplish many of ... Small nucleolar RNAs (snoRNAs) are conserved noncoding RNAs best studied as ribonucleoprotein (RNP) guides in RNA modification ... RNA functions at enhancers remain mysterious. Here we show that the 7SK small nuclear RNA (snRNA) inhibits enhancer ... Dissecting noncoding and pathogen RNA-protein interactomes RNA-A PUBLICATION OF THE RNA SOCIETY Flynn, R. A., Martin, L., ...

Small non-coding RNAs, represented by RNA molecules smaller than 200 nucleotides, include microRNAs, snoRNAs, piRNAs and tRNAs ... untranslated region of coding RNAs by complementary base pairing and thus promote their degradation and/or translational ... Ma, L.; Bajic, V.B.; Zhang, Z. On the classification of long non-coding RNAs. RNA Biol. 2013, 10, 924-933. [Google Scholar] [ ... Long non-coding RNAs [51], i.e., RNA molecules with sequences longer than 200 nucleotides, include several subtypes such as ...

The microRNA present in the cells of our body typically target both the 3′-UTR (three prime untranslated region) region of the ... A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and ... Tiny RNA That Should Attack COVID-19 Coronavirus Diminish With Age, Disease TOPICS:AgingAugusta UniversityCell BiologyCOVID-19 ... Be the first to comment on "Tiny RNA That Should Attack COVID-19 Coronavirus Diminish With Age, Disease". ...

... and antisense noncoding RNAs (lncRNAs). The identification of small RNAs that regulate mRNA translation and half-life did not ... to discover that eukaryotic genes are mosaics of mRNA sequences interrupted by large tracts of transcribed but untranslated ... he has backed off this claim a little bit by conceding that Crick allowed for functional RNAs but that proteins were the only ... Only a relatively small group of transcripts have a proven biological function ("only 1000 lncRNAs out of 60,000 were conserved ...

RNA 96% * Inteins 70% * Virulence 40% * Small Untranslated RNA 28% 21 Scopus citations ...

... and antisense noncoding RNAs (lncRNAs). The identification of small RNAs that regulate mRNA translation and half-life did not ... to discover that eukaryotic genes are mosaics of mRNA sequences interrupted by large tracts of transcribed but untranslated ... he has backed off this claim a little bit by conceding that Crick allowed for functional RNAs but that proteins were the only ... Mattick, J.S. (2023) RNA out of the mist. TRENDS in Genetics 39:187-207. [doi: 10.1016/j.tig.2022.11.001,/p, ...

The role of small non-coding RNAs in genome stability and chromatin organization. van Wolfswinkel, J. C. & Ketting, R. F., 2010 ... The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA. Splinter, E., de Wit, E ... RNA Interference 100% * Argonaute Proteins 81% * Small Untranslated RNA 63% * Protein 43% ...

Small Untranslated RNA 20% * Genes 19% * Epigenomics 18% * Chromosomes 17% * Microsatellite Repeats 17% ...

miRNAs are a family of small non-coding RNAs that emerged as significant and versatile regulators involved in regulation of ... miRNAs are a family of small noncoding RNAs that emerged as significant and versatile regulators involved in regulation of ... 3. Stefani G, Slack F. Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol. (2008) 9:219-30. doi: 10.1038/ ... untranslated region (UTR) of target mRNAs (1). The specificity of miRNAs is thought to be mainly mediated by the residues 2-8 ...

HCV is a small (50 nm) single-stranded RNA member of the flaviviridae family. The RNA has one open reading frame, preceded by a ... ribosome-binding site within a UTR (untranslated region). The open reading frame encodes a 3,011 amino acid protein that is ... The HCV RNA polymerase is highly error prone, and the sequences of HCV genomes display enormous amounts of variation. Six ... The amino acid sequences include nucleocapsid, envelope, protease, helicase, transmembrane, and RNA polymerase proteins. ...