Long non-coding RNA - Wikipedia
Long non-coding RNAs (long ncRNAs, lncRNA) are a type of RNA, generally defined as transcripts more than 200 nucleotides that ... "Long Non-Coding RNAs in the Regulation of Gene Expression: Physiology and Disease". Non-Coding RNA. 5 (1): 17. doi:10.3390/ ... "Long Non-Coding RNA (lncRNA) Roles in Cell Biology, Neurodevelopment and Neurological Disorders". Non-Coding RNA. 7 (2): 36. ... "On the classification of long non-coding RNAs". RNA Biology. 10 (6): 925-933. doi:10.4161/rna.24604. PMC 4111732. PMID 23696037 ...
RNA, Long Noncoding | Broad Institute
Kelley D, Rinn J. Transposable elements reveal a stem cell-specific class of long noncoding RNAs. Genome Biol. 2012;13(11):R107 ... Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements. Nat Genet. 2022;54(10):1504-1513. doi: ...
Genome regulation by long noncoding RNAs
The discovery of extensive transcription of large RNA transcripts that do not code for proteins, termed long noncoding RNAs ( ... The central dogma of gene expression is that DNA is transcribed into messenger RNAs, which in turn serve as the template for ... The discovery of extensive transcription of large RNA transcripts that do not code for proteins, termed long noncoding RNAs ( ... Genome regulation by long noncoding RNAs Annu Rev Biochem. 2012;81:145-66. doi: 10.1146/annurev-biochem-051410-092902. ...
Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat | Nature
Many of the RNAs transcribed from the genome have as yet no known function. One such long non-coding RNA (lncRNA) is an ... This generates a vast repertoire of transcripts that includes protein-coding messenger RNAs, long non-coding RNAs (lncRNAs) and ... Antisense Uchl1 RNA is then required for the association of the overlapping sense protein-coding mRNA to active polysomes for ... and may have potential as RNA therapeutics. Most of the mammalian genome is transcribed1,2,3. ...
Long-noncoding RNA regulates repair of DNA breaks in triple-negative breast cancer cells | ScienceDaily
... researchers identified a non-coding RNA that is overexpressed in triple-negative breast cancer cells and regulated by the tumor ... Long-noncoding RNA regulates repair of DNA breaks in triple-negative breast cancer cells. Findings give new insight into ... The discovery of long non-coding RNA (lncRNA) has dramatically changed the understanding of the biology of diseases such as ... Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer. Nature Structural & ...
TROLLS: Inhibition Of TAp63 Regulated Oncogenic Long Noncoding RNAs (T | Moffitt
Long Noncoding RNAs Archives - Reasons to Believe
High expression of long non-coding RNA ANRIL is associated with poor prognosis in hepatocellular carcinoma
... Int J Clin Exp ... Introduction: long non-coding RNA ANRIL (lncRNA ANRIL) has been demonstrated to play a crucial role in cancer progression. ... Long Hua 1 , Chen-Yu Wang 1 , Kun-Hou Yao 1 , Jiang-Tao Chen 1 , Jun-Jie Zhang 1 , Wan-Li Ma 1 ... Small interfering RNA (siRNA) was used to silence lncRNA ANRIL and to explore the effects of reduced lncRNA ANRIL expression on ...
Long noncoding RNAs for pluripotency and cell fate commitment - CIRM
Many long noncoding RNAs emanate from active gene switches called enhancers. We found that one noncoding RNA named 7SK is ... particular through newly recognized molecules called long noncoding RNAs. We found that specific long RNAs are involved in ... Long Noncoding RNAs in Cell-Fate Programming and Reprogramming. (PubMed: 24905165). *Cell Stem Cell (2014): m(6)A RNA ... Our research has shown that a new class of genes called long noncoding RNAs appear to have an important role in telling which ...
SFARI | The role of the PTCHD1-antisense long noncoding RNA in autism
Frontiers | Long Non-coding RNAs as Functional and Structural Chromatin Modulators in Acute Myeloid Leukemia
Amongst these, long non-coding RNAs (lncRNAs) are species of 200 bp to ,100 K bp in length, that recognize, and bind unique and ... Amongst these, long non-coding RNAs (lncRNAs) are species of 200bp to ,100K bp in length, that recognize and bind unique and ... on their interaction with untranslated RNA molecules for guidance to particular targets on DNA. Non (protein)-coding RNAs are ... Non (protein)-coding RNAs are the most abundant transcriptional products of the coding genome, and comprise several different ...
Long non‑coding RNA DLEU1 promotes cell proliferation of glioblastoma multiforme
Long non-coding RNA (lncRNA) is a type of RNA that contains over 200 nucleotides and that does not encode protein (5,6). ... Shi Y, Wang Y, Luan W, Wang P, Tao T, Zhang J, Qian J, Liu N and You Y: Long non-coding RNA H19 promotes glioma cell invasion ... Jiang X, Yan Y, Hu M, Chen X, Wang Y, Dai Y, Wu D, Wang Y, Zhuang Z and Xia H: Increased level of H19 long noncoding RNA ... Li X, Li Z, Liu Z, Xiao J, Yu S and Song Y: Long non-coding RNA DLEU1 predicts poor prognosis of gastric cancer and contributes ...
The long non-coding RNA landscape of Candida yeast pathogens | IRB Barcelona
Frontiers | Long Non-coding RNAs and mRNAs Expression Profiles of Monocyte-Derived Dendritic Cells From PBMCs in AR
... and messenger RNAs (mRNAs) expression profiles of monocyte-derived dendritic cells (DCs) obtained from peripheral blood ... and messenger RNAs (mRNAs) expression profiles of monocyte-derived dendritic cells (DCs) obtained from peripheral blood ... ObjectiveThe objective of this study is to explore the long non-coding RNAs (lncRNAs) ... The objective of this study is to explore the long noncoding RNAs (lncRNAs) ...
Altmetric - Diabetic cardiomyopathy: The role of microRNAs and long non-coding RNAs
Diabetic cardiomyopathy: The role of microRNAs and long non-coding RNAs. Overview of attention for article published in ...
Long noncoding RNA ZNFX1-AS1 promotes the invasion and proliferation of gastric cancer cells by regulating LIN28 and CAPR1N1
Keywords: Long noncoding RNA, ZNFX1-AS1, Gastric cancer, Biomarker, Invasion, Proliferation Core Tip: Long noncoding RNA ( ... Zhuo ZL, Xian HP, Sun YJ, Long Y, Liu C, Liang B, Zhao XT. Long noncoding RNA ZNFX1-AS1 promotes the invasion and proliferation ... Long noncoding RNA (lncRNA) ZNFX1-AS1 (ZFAS1) is a newly discovered lncRNA, but its diagnostic value in gastric cancer is ... Long noncoding RNA ZNFX1-AS1 promotes the invasion and proliferation of gastric cancer cells by regulating LIN28 and CAPR1N1 ...
Medical Science Monitor | The Long Noncoding RNA, LINC01555, Promotes Invasion and Metastasis of Colorectal Cancer by...
This study aimed to investigate the role of the long noncoding RNA (lncRNA), LINC01555, on the migration and invasion of ... The Long Noncoding RNA, LINC01555, Promotes Invasion and Metastasis of Colorectal Cancer by Activating the Neuropeptide, ... allowing to download articles and share them with others as long as they credit the authors and the publisher, but without ...
Form Meets Function in Long Non-Coding RNAs
Many recent functional studies have demonstrated clear visible phenotypes for long non-coding RNAs, quieting some skeptics ... Thousands of long non-coding RNAs have been discovered in recent years, leading some to claim there may be as many functional ... Many recent functional studies have demonstrated clear visible phenotypes for long non-coding RNAs, quieting some skeptics ... In the wake of these findings, a second controversy has raged - do these long RNAs have structures and are they important for ...
ONCOLOGIE | Serum Long Non-Coding RNA CCAT2 is a Potential Diagnostic and Prognostic Marker for Gastric Cancer
This study aims to explore the role of serum long non-coding RNA (lncRNA) colon cancer-associated transcript 2 (CCAT2) as a ... Serum Long Non-Coding RNA CCAT2 is a Potential Diagnostic and Prognostic Marker for Gastric Cancer. Fei Han1, Jianghong Qu2, ... 2021). Serum Long Non-Coding RNA CCAT2 is a Potential Diagnostic and Prognostic Marker for Gastric Cancer. Oncologie, 23(1), ... Aim: This study aims to explore the role of serum long non-coding RNA (lncRNA) colon cancer-associated transcript 2 (CCAT2) as ...
Long noncoding RNA 00507/miRNA-181c-5p/TTBK1/MAPT axis regulates tau hyperphosphorylation in Alzheimer's disease. - Physician's...
Long noncoding RNA 00507/miRNA-181c-5p/TTBK1/MAPT axis regulates tau hyperphosphorylation in Alzheimers disease.. Sep 7, 2020 ... qRT-PCR evaluated the RNA expression of linc00507, miR-181c-5p and MAPT/TTBK1. The interactions between the genes were studied ... as a competitive endogenous RNA (ceRNA). MAPT (encoding the tau protein) and TTBK1 (encoding a tau kinase) were identified as ... qRT-PCR evaluated the RNA expression of ...
Additional file 1 of Long non-coding RNA TUG1 knockdown promotes autophagy and improves acute renal injury in ischemia...
Additional file 1 of Long non-coding RNA TUG1 knockdown promotes autophagy and improves acute renal injury in ischemia- ... Renal ischemia-reperfusionAutophagyApoptosisLong noncoding RNA TUG1PTENmcroRNA-29 ... Additional file 1 of Long non-coding RNA TUG1 knockdown promotes autophagy and improves acute renal injury in ischemia- ...
Correction to "Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells"...
Correction to "Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells" ... Correction to "Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells" ... Correction to "Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells" ... Correction to "Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells" ...
Hypermethylation-mediated downregulation of long non-coding RNA MEG3 inhibits osteogenic differentiation of bone marrow...
Long non-coding RNA UASR1 promotes proliferation and migration of breast cancer cells through the AKT/mTOR pathway
Long non-coding RNAs (lncRNAs) are non-coding RNAs longer than 200 nucleotides that function as regulatory factors in many ... Some of them are for non-coding RNA transcripts longer than 200 nucleotides, called long non-coding RNAs (lncRNAs) [1, 2]. To ... Noncoding RNAs involved in mammary gland development and tumorigenesis: theres a long way to go. J Mammary Gland Biol ... Long non-coding RNA H19 regulates glioma angiogenesis and the biological behavior of glioma-associated endothelial cells by ...
Speaker: Debanjan Saha - 'Characterization of long-noncoding RNAs in prostate and pancreatic cancer through single cell...
Global identification of long non-coding RNAs involved in the induction of spinach flowering | BMC Genomics | Full Text
... non-coding RNA molecules like long non-coding RNAs (lncRNAs) were not investigated yet. Herein, we used bioinformatic ... non-coding RNA molecules like long non-coding RNAs (lncRNAs) were not investigated yet. Herein, we used bioinformatic ... RNA sequencing and functional analysis implicate the regulatory role of long non-coding RNAs in tomato fruit ripening. Journal ... Analysis of long noncoding RNA and mRNA using RNA sequencing during the differentiation of intramuscular preadipocytes in ...
Integrated Analysis of Long Non-Coding RNA and mRNA Expression Profile in Pancreatic Cancer Derived Exosomes Treated Dendritic...
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell. 2011;147:358-69 ... Long noncoding RNAs (lncRNAs) (,200 nucleotides) interact with DNA, RNA, or protein molecules to regulate gene expression and ... Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder ... Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer. Tumour biology: the journal ...
HAYA Therapeutics Completes CHF 18 Million Seed Financing to Advance Anti-fibrotic Therapies Targeting Long Non-Coding RNAs |...
HAYA Therapeutics Completes CHF 18 Million Seed Financing to Advance Anti-fibrotic Therapies Targeting Long Non-Coding RNAs ... HAYA Therapeutics Completes CHF 18 Million Seed Financing to Advance Anti-fibrotic Therapies Targeting Long Non-Coding RNAs * ... The companys discovery engine focuses on long non-coding RNAs (lncRNAs) within the "dark matter" of the human genome -- key ... Lead therapeutic candidate targets Wisper, a cardiac fibroblast-enriched long non-coding RNA(lncRNA), for the treatment of non- ...
Profiling of testis-specific long noncoding RNAs in mice | BMC Genomics | Full Text
Recent studies have discovered that long noncoding RNAs (lncRNAs) are novel regulatory molecules that play important roles in ... We categorized the testis-specific lncRNAs and found that a large portion corresponded to long intergenic ncRNAs (lincRNAs). ... Hong, S.H., Kwon, J.T., Kim, J. et al. Profiling of testis-specific long noncoding RNAs in mice. BMC Genomics 19, 539 (2018). ... Liang M, Li W, Tian H, Hu T, Wang L, Lin Y, Li Y, Huang H, Sun F. Sequential expression of long noncoding RNA as mRNA gene ...
Chromatin signatures at transcriptional start sites separate two equally populated yet distinct classes of intergenic long...
These two classes of 5′ capped and polyadenylated RNA transcripts are indistinguishable with regard to their length, number of ... Mammalian transcriptomes contain thousands of long noncoding RNAs (lncRNAs). Some lncRNAs originate from intragenic enhancers ... Kutter C, Watt S, Stefflova K, Wilson MD, Goncalves A, Ponting CP, Odom DT, Marques AC: Rapid turnover of long noncoding RNAs ... Kelley D, Rinn J: Transposable elements reveal a stem cell-specific class of long noncoding RNAs. Genome Biol. 2012, 13: R107- ...