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*  Transposable elements (TEs) contribute to stress-related long intergenic noncoding RNAs in Plants | lncRNA Blog
... short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs ... Functional dissection of NEAT1 using genome editing. May 22, 2017. Leave a Reply Cancel reply. Your email address will not be ... microrna micrornas miRNA Nature ncRNA NEAT1 non-coding rna non-coding rnas noncoding RNA post-doc Prognosis Prostate Cancer RNA ... HOTAIR junk dna lincrna lincRNAs lncrna lncrnas long non-coding RNA long non-coding RNAs long noncoding rna Long Noncoding RNAs ...
http://www.lncrnablog.com/transposable-elements-tes-contribute-to-stress-related-long-intergenic-noncoding-rnas-in-plants/
*  RNA editing
... Peter Schuessler schuessl at uni-duesseldorf.de Tue Mar 12 10:51:58 EST 1996 *Previous message: Trypanosome ... hallo out there, have anybody knowledge of RNA editing in trematodes or other parasites (without kinetoplastida)? thanks ...
http://www.bio.net/bionet/mm/parasite/1996-March/001401.html
*  RCas9: A programmable RNA editing tool | EurekAlert! Science News
A powerful scientific tool for editing the DNA instructions in a genome can now also be applied to RNA as Berkeley Lab ... researchers have demonstrated a means by which the CRISPR/Cas9 protein complex can be programmed to recognize and cleave RNA at ... RCas9: A programmable RNA editing tool. DOE/Lawrence Berkeley National Laboratory. Journal. Nature. Funder. National Institutes ... A powerful scientific tool for editing the DNA instructions in a genome can now also be applied to RNA, the molecule that ...
https://www.eurekalert.org/pub_releases/2014-10/dbnl-rap100314.php
*  Squid Enrich Their DNA "Blueprint" Through Prolific RNA Editing
By comparing DNA and RNA sequences from the squid brain, the team found that 60 percent of the RNA transcripts had been edited ... RNA editing was thought to be sparingly used, based on a limited number of studies in mammals and flies. But recently, MBL ... "In squid, RNA editing is so pervasive that the central dogma should be modified to include this process," Rosenthal says. " ... Alon S et al (2015) The majority of transcripts in the squid nervous system are extensively recoded by A-to-I RNA editing. ...
http://www.mbl.edu/blog/squid-enrich-their-dna-blueprint-through-prolific-rna-editing/
*  Largest, most accurate list of RNA editing sites | EurekAlert! Science News
The list yielded several biological insights and can aid further research on RNA transcription because flies are a common model ... Researchers have compiled the largest and most rigorously validated list to date of the genetic sites in fruit flies where RNA ... transcribed from DNA is then edited by an enzyme to affect a wide variety of fundamental biological functions. ... IMAGE: The two two dark humps in the top row (representing fly RNA) are missing in flies that lack the enzyme to edit RNA ( ...
https://www.eurekalert.org/pub_releases/2013-09/bu-lma092613.php
*  RNA Editing in Corals Stupefies Evolution | The Institute for Creation Research
In fact, they found over 500,000 sites in coral genes where the sequence had been altered with RNA editing. The RNA editing ... A common type of RNA editing in animal cells involves the alteration of an adenosine base to an inosine base (A-to-I editing). ... it turns out that the bases in the RNA can be changed dynamically on the fly in a fine-tuning process called RNA editing. ... A-to-I RNA Editing in the Earliest-Diverging Eumetazoan Phyla. Molecular Biology and Evolution. 34 (8): 1890-1901. ...
https://www.icr.org/article/rna-editing-corals-stupefies-evolution
*  RNA Editing: Biocomplexity Hits a New High | The Institute for Creation Research
RNA editing targets single bases. One of the most common types of RNA editing in animals involves the changing of an adenosine ... RNA Biol. 7 (2): 205-212.. * Nishikura, K. 2010. Functions and regulation of RNA editing by ADAR deaminases. Annu Rev Biochem. ... it has also been discovered that another form of dynamic RNA alteration exists called RNA editing. Unlike alternative splicing ... This type of editing in both coding and non-coding RNAs has been found to have profound effects on gene expression.3 In ...
https://www.icr.org/article/rna-editing-biocomplexity-hits-new/
*  GUN1 interacts with MORF2 to regulate plastid RNA editing during retrograde signaling | PNAS
NF treatment also affected RNA editing in plastids (16, 17). RNA editing is a posttranscriptional modification of RNA that ... In this study, we have discovered an unexpected role for GUN1 in plastid RNA editing, as gun1 mutations affect RNA-editing ... GUN1 plays a direct role in RNA editing by physically interacting with MULTIPLE ORGANELLAR RNA EDITING FACTOR 2 (MORF2). MORF2 ... How might a change in RNA editing trigger a retrograde signaling pathway? Among the editing sites that exhibit similar editing- ...
https://www.pnas.org/content/116/20/10162
*  RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself | Science
In addition to RNA editing, additional functions have been proposed for ADAR1. To determine the specific role of RNA editing by ... RNA editing helps identify cellular RNAs. Adenosine bases in messenger RNA (mRNAs) can be enzymatically modified and changed ... The principal RNA-editing enzyme modifies cellular RNAs to prevent their erroneous identification as foreign RNA. ... The principal RNA-editing enzyme modifies cellular RNAs to prevent their erroneous identification as foreign RNA. ...
http://science.sciencemag.org/content/349/6252/1115
*  RNA Editing - Hardcover - Brenda L. Bass - Oxford University Press
Numerous examples of RNAs known to be edited are provided throughout the volume, but most importantly, the book highlights the ... amazing mechanistic diversity found among the various types of RNA editing. ... RNA Editing devotes a chapter to each of the major types of this form of RNA processing. Each chapter is written by a leader in ... 2. RNA editing in Physarum polycephalum, Jonatha M. Gott. 3. RNA editing in plant mitochondria and chloroplasts, Ralph Bock. 4 ...
https://global.oup.com/academic/product/rna-editing-9780199638154?cc=us&lang=en&tab=reviews
*  Z-RNA editing enzyme complex - Stock Image C035/8333 - Science Photo Library
Computer model showing the structure of the human Zalpha domain of the RNA-editing enzyme ADAR1 (brown-orange, blue-purple) ... complexed with a synthetic Z-RNA (blue-green, yellow). - Stock Image C035/8333 ... Human Z-RNA editing enzyme complexed with Z-RNA (Z-ribonucleic acid). ... Caption: Human Z-RNA editing enzyme complexed with Z-RNA (Z-ribonucleic acid). Computer model showing the structure of the ...
http://www.sciencephoto.com/media/850741/view
*  RNA Editing by Adenosine Deaminases That Act on RNA
What is RNA Editing?. Like RNA splicing, RNA editing alters the sequence of an RNA from that encoded in the DNA. Typically, a ... Does RNA Editing Affect RNA splicing?. As illustrated in Figure 3, the dsRNA required for editing often encompasses sequences ... An Overview of RNA Editing by Adenosine Deamination. RNA editing by adenosine deamination is catalyzed by members of an enzyme ... ADARs are RNA editing enzymes that target double-stranded regions of nuclear-encoded RNA and viral RNA. These enzymes are ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC1823043/?lang=en-ca
*  Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish
Loss of Fmrp resulted in a mild increase in RNA editing in the coding sequences of conserved synaptic genes. These findings ... Thus, we characterized global RNA editing in the zebrafish transcriptome and used a microfluidic-based high-throughput ... The genetic cause of this disorder is the silencing of the fmr1 gene, which encodes the RNA-binding protein Fmrp. This protein ... propose that altered RNA editing levels may affect neuronal and behavioral deficiencies in FXS. ...
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005702
*  Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing | Science
RNA editing occurs when ADARs (adenosine deaminases acting on RNA) bind to an extended RNA duplex within target RNAs (17, 18). ... The enlarged set of nonrepetitive RNA editing targets may help unravel rules of RNA editing in human diseases and behavior. ... A comprehensive set of several hundred human RNA editing sites was detected by comparing genomic DNA with RNAs from seven ... This efficient approach greatly expands the repertoire of RNA editing targets and can be applied to studies involving RNA ...
http://science.sciencemag.org/content/324/5931/1210?ijkey=77144a054ee3ddc9fa0c7464a93f18bfea6d95ac&keytype2=tf_ipsecsha
*  Re: What is the physical basis behind the A/G mixed signal from RNA editing?
... Date: Sun Oct 31 14:38:42 2010. Posted By: Karl A ... Maas S, Rich A, Nishikura K. (2003) A-to-I RNA editing: recent news and residual mysteries. J. Biol. Chem. 278 (3), 1391-1394. ... Seeburg PH, Higuchi M, Sprengel R. (1998) RNA editing of brain glutamate receptor channels: mechanism and physiology. Brain ... A-to-I RNA editing) well. The enzyme adenosine deaminase catalyzes the site specific deamination of the pre-mRNA, producing an ...
http://www.madsci.org/posts/archives/2010-10/1288588947.Mb.r.html
*  RNA editing - Wikipedia
RNA editing website DARNED (DAtabase of RNa EDiting in humans) A-to-I editing website C-to-U Editing Website. ... A-to-I editing is the main form of RNA editing in mammals and occurs in regions of double-stranded RNA (dsRNA). Adenosine ... Therefore, a RNA transcript requiring extensive editing will need more than one guide RNA and editosome complex. The editing ... Editing events may include the insertion, deletion, and base substitution of nucleotides within the edited RNA molecule. RNA ...
https://en.wikipedia.org/wiki/RNA_editing
*  RNA editing of nuclear transcripts in Arabidopsis thaliana | BMC Genomics | Full Text
Some editing sites, such as adenosine (A)-to-U editing loci, were found to be surrounded by peculiar elements. The editing ... suggesting site-specific editing. Furthermore, RNA editing is potentially implicated in new start or stop codon generation, and ... no systemic study on RNA editing of plant nuclear genes has been reported. Here, a transcriptome-wide search for editing sites ... RNA editing in the precursor microRNAs (pre-miRNAs) of ath-miR854 family, resulting in secondary structure transformation, ...
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-11-S4-S12
*  RNA editing contributes to myeloma pathogenesis | MDedge Hematology and Oncology
ADAR1-mediated editing of messenger RNA may be an important mechanism in multiple myeloma pathogenesis.Major finding: ADAR1- ... mediated editing of NEIL1 leads to a weakened DNA base excision repair mechanism.Study details: Experimental series using ... RNA editing contributes to myeloma pathogenesis. Teoh PJ et al. Blood. 2018;132(12):1304-17. Publish date:. November 14, 2018. ... Key clinical point: ADAR1-mediated editing of messenger RNA may be an important mechanism in multiple myeloma pathogenesis. ...
https://www.mdedge.com/hematology-oncology/clinical-edge/summary/multiple-myeloma/rna-editing-contributes-myeloma
*  RNA Editing: Changing the Code in Plants, Animals and Parasites | HSTalks
Stephen Hajduk on RNA Editing: Changing the Code in Plants, Animals and Parasites, part of a collection of online lectures. ... RNA Editing: Changing the Code in Plants, Animals and Parasites. *Prof. Stephen Hajduk - University of Georgia, USA ... RNA Editing: Changing the Code in Plants, Animals and Parasites. Embed in course/own notes ... Hajduk, S. (2007, October 1). RNA Editing: Changing the Code in Plants, Animals and Parasites [Video file]. In The Biomedical ...
https://hstalks.com/t/631/rna-editing-changing-the-code-in-plants-animals-an/?biosci
*  Glur2 RNA editing - Wikipedia
... editing. Adenosine deaminases acting on RNA (ADARs) are the RNA editing enzymes responsible for A-to-I editing. ADARs deaminate ... Editing of the pre-mRNA results in conversion to Arg (CGG) being encoded at this position. Editing alters Ca2+ permeability. ... Editing occurs in 100% of transcripts in human brain. Editing levels are lower in other tissues. Deletion analysis determined ... Deficiency also inhibits editing of the Q/R site of Glur2 thereby increasing the level of unedited Glur2 resulting in increased ...
https://en.wikipedia.org/wiki/Glur2_RNA_editing
*  Complex regulation of ADAR-mediated RNA-editing across tissues | BMC Genomics | Full Text
Here we present an analysis of RNA-editing patterns from 9 different tissues harvested from a single mouse. For comparison, we ... Dysfunction of A-to-I RNA editing can have catastrophic effects, particularly in the central nervous system. Thus, ... Together, these data suggest a complex regulation of the RNA-editing process beyond transcript expression levels. ... understanding how the process of RNA-editing is regulated has important implications for human health. However, at present, ...
https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-015-2291-9
*  Questioning the evidence for non-canonical RNA editing in humans « Genomes Unzipped
Known A-,I RNA editing sites do not have the above two properties (21/23 RDD sites that were previously observed as A-,I edits ... Of course, it remains plausible that previously unidentified forms of RNA editing are active in humans, and RNA sequencing ... 2012) Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. doi:10.1038/nbt.2122. ... rather than resulting from RNA editing.. In their response, Li et al. [5] present no new validation experiments involving RNA ...
http://genomesunzipped.org/2012/03/questioning-the-evidence-for-non-canonical-rna-editing-in-humans.php
*  US5677428A - RNA editing enzyme and methods of use thereof - Google Patents
U. Kim et al, "Double-stranded RNA Adenosine Deaminase: A Potential Agent for RNA Editing?", in RNA Editing, R. Benne, Ed. ( ... U. Kim et al, Double stranded RNA Adenosine Deaminase: A Potential Agent for RNA Editing , in RNA Editing, R. Benne, Ed. (Simon ... RNA editing enzyme and methods of use thereof US08457459 Expired - Lifetime US5677428A (en) 1994-02-17. 1995-06-01. RNA editing ... RNA editing enzyme and methods of use thereof US08457459 US5677428A (en) 1994-02-17. 1995-06-01. RNA editing enzyme and methods ...
https://patents.google.com/patent/US5677428
*  Abstract 3356: Novel evidence for AZIN1 RNA editing-mediated oncogenic role in colorectal cancer | Cancer Research
Materials and methods: We systematically and comprehensively investigated RNA editing in the AZIN1 gene using the RNA editing ... RNA editing has been shown to be a potential epigenetic event in human cancers. One of the most important RNA editing gene ... Results: Using RESSqPCR, AZIN1 RNA editing levels were analyzed in two CRC cohorts. AZIN1 editing levels were significantly ... Abstract 3356: Novel evidence for AZIN1 RNA editing-mediated oncogenic role in colorectal cancer. Kunitoshi Shigeyasu, Shusuke ...
http://cancerres.aacrjournals.org/content/77/13_Supplement/3356
*  Recoding RNA Editing of AZIN1 Is Oncogenic in Hepatocellular Carcinoma | Cancer Discovery
Recoding RNA Editing of AZIN1 Is Oncogenic in Hepatocellular Carcinoma Message Subject (Your Name) has forwarded a page to you ... Major finding: RNA editing of AZIN1 is increased in HCC and enhances tumor incidence and progression. ... Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma. Nat Med 2013 Jan 6 [Epub ahead of print]. ... RNA editing is a regulatory mechanism in which nucleotides are altered posttranscriptionally and most frequently involves ...
http://cancerdiscovery.aacrjournals.org/content/early/2013/01/23/2159-8290.CD-RW2013-017