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*  Direct Transfer of Synthetic Double-Stranded RNA into Protoplasts of Arabidopsis thaliana | SpringerLink
RNA interference (RNAi) is widely used as a reverse genetic approach for functional analysis of plant genes. Constitutive or ... 1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811.PubMed ... Double-stranded (ds) RNA interference (RNAi) is widely used as a reverse genetic approach for functional analysis of plant ... Jung H., Zhai Z., Vatamaniuk O.K. (2011) Direct Transfer of Synthetic Double-Stranded RNA into Protoplasts of Arabidopsis ...
https://link.springer.com/protocol/10.1007%2F978-1-61779-123-9_8
*  Sense and antisense transcripts of convergent gene pairs in Arabidopsis thaliana can share a common polyadenylation region |...
RNA processing, post-transcriptional ; RNA, antisense ; RNA, double-stranded ; RNA, messenger ; transcription, genetic ; ... transcripts that terminate within the same polyadenylation region as the antisense transcripts encoded by the opposite strand. ...
https://air.unimi.it/handle/2434/243974
*  Double-stranded RNA Viruses
... Version 05 February 2006 (temporary). http://tolweb.org/Double-stranded_RNA_Viruses/21833/2006.02. ... Double-stranded RNA Viruses Click on an image to view larger version & data in a new window ... Transmission electron micrograph of intact rotavirus particles, double-shelled. Distinctive rim of radiating capsomeres. ... Double-stranded RNA Viruses Page Content. *Title Illustrations. *About This Page. articles & notes. *Double-stranded RNA ...
http://tolweb.org/Double-stranded_RNA_Viruses/21833
*  Double-stranded RNA induces mRNA degradation in Trypanosoma brucei | PNAS
Small nucleolar RNA interference induced by antisense or double-stranded RNA in trypanosomatids ... double-stranded RNA;. GFP,. green fluorescent protein;. PFR,. paraflagellar rod;. 5′ UTR,. 5′ untranslated region. ... Double-stranded RNA induces mRNA degradation in Trypanosoma brucei. Huân Ngô, Christian Tschudi, Keith Gull, and Elisabetta ... Double-stranded RNA induces mRNA degradation in Trypanosoma brucei Message Subject (Your Name) has sent you a message from PNAS ...
https://www.pnas.org/content/95/25/14687?ijkey=9d0340ee2dfa41543c099a91d2b8bffd093b022a&keytype2=tf_ipsecsha
*  Patent US6506559 - Genetic inhibition by double-stranded RNA - Google Patents
The RNA has a region with double-stranded structure. Inhibition is sequence-specific in that the nucleotide sequences of the ... The present invention is distinguished from prior art interference in gene expression by antisense or triple-strand methods. ... A process is provided of introducing an RNA into a living cell to inhibit gene expression of a target gene in that cell. The ... duplex region of the RNA and of a portion of the target gene are identical. ...
http://www.google.com/patents/US6506559?dq=7493558
*  Double-stranded RNA viruses - Wikipedia
... dubbed Double-stranded RNA (dsRNA) Activated Caspase Oligomerizer (DRACO)... Patton, John T., ed. (2008). Segmented Double- ... Double-stranded (ds) RNA viruses are a diverse group of viruses that vary widely in host range (humans, animals, plants, fungi ... It is a double-stranded RNA non-enveloped virus The members of genus Orbivirus within the Reoviridae family are arthropod borne ... 2008). "The Yeast dsRNA Virus L-A Resembles Mammalian dsRNA Virus Cores". Segmented Double-stranded RNA Viruses: Structure and ...
https://en.wikipedia.org/wiki/Double-stranded_RNA_viruses
*  Microglia Recognize Double-Stranded RNA via TLR3 | The Journal of Immunology
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5: ... Microglia Recognize Double-Stranded RNA via TLR3. Terrence Town, David Jeng, Lena Alexopoulou, Jun Tan and Richard A. Flavell ... Microglia Recognize Double-Stranded RNA via TLR3 Message Subject (Your Name) has forwarded a page to you from The Journal of ... Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413: 732-738. ...
https://www.jimmunol.org/content/176/6/3804?ijkey=9fe22f44cb160651e67c671a6993830bbd67ea0c&keytype2=tf_ipsecsha
*  Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana | PNAS
... it seems possible that cellular RNA-dependent RNA polymerase could be involved in the conversion of single-stranded RNA to ... Double-stranded RNA (dsRNA)-mediated interference with expression of specific genes has been observed in a number of organisms ... Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana. Chiou-Fen Chuang and Elliot M. ... An Intron Sense Suppression Construct Targeting Soybean FAD2-1 Requires a Double-Stranded RNA-Producing Inverted Repeat T-DNA ...
https://www.pnas.org/content/97/9/4985?ijkey=d188d4b15009430365c11221e1fcb489f21cc3a1&keytype2=tf_ipsecsha
*  Double stranded RNA treatment can reduce fertility of adult house fly pests | EurekAlert! Science News
Double stranded RNA (dsRNA) can effectively reduce house fly fertility, and shows promise as a pest control method, according ... Double stranded RNA treatment can reduce fertility of adult house fly pests Fly-specific dsRNA interfered with gene expression ... Double Stranded RNA treatment Can Reduce Fertility of Adult House Fly Pests (IMAGE) view more ... Double stranded RNA (dsRNA) can effectively reduce house fly fertility, and shows promise as a pest control method, according ...
https://eurekalert.org/pub_releases/2018-01/p-dsr011118.php
*  Adar - Double-stranded RNA-specific editase Adar - Drosophila melanogaster (Fruit fly) - Adar gene & protein
... edits RNA-binding protein Rnp4F. A-to-I editing of pre-mRNAs acts predominantly through nervous system targets to affect adult ... Has A-to-I RNA editing activity on extended dsRNA: ... Double-stranded RNA-specific editase AdarAdd BLAST. 676. ... Cluster: Double-stranded RNA-specific editase Adar. 4. Q9NII1-2. M9NGI0. Q9NII1-6. M9NFQ6. Drosophila melanogaster (Fruit fly) ... Cluster: Double-stranded RNA-specific editase Adar. 55. Q9NII1-2. M9NGI0. Q9NII1-6. M9NFQ6. UPI00078ADFB4. A0A0Q5T786. ...
http://www.uniprot.org/uniprot/Q9NII1
*  RCSB PDB - Protein Feature View - Interferon-induced, double-stranded RNA-activated protein kinase - P19525 (E2AK2...
Exerts its antiviral activity on a wide range of DNA and RNA viruses including hepatitis C virus (HCV), hepatitis B virus (HBV ... Microbial infection) Interacts with human herpes simplex virus 1 (HHV-1) protein US11 in an RNA-dependent manner (PubMed: ...
http://www.rcsb.org/pdb/protein/P19525
*  Virus-Specific Double-Stranded RNA in Poliovirs-Infected Cells | Science
Virus-Specific Double-Stranded RNA in Poliovirs-Infected Cells Message Subject. (Your Name) has forwarded a page to you from ... It is therefore, considered to be a double-stranded form of poliovirus RNA. A significant amount of this material is found in ... Poliovirus-infected HeLa cells contain a small amount of an RNA that sediments slightly faster than 16S. This RNA is less dense ... than viral RNA and resists digestion by ribonuclease. ... Virus-Specific Double-Stranded RNA in Poliovirs-Infected Cells ...
https://science.sciencemag.org/content/143/3610/1034.abstract
*  Cytosolic Viral Sensor RIG-I Is a 5'-Triphosphate-Dependent Translocase on Double-Stranded RNA | Science
... and the regulatory domain prevents signaling in the absence of viral RNA. 5′-triphosphate and double-stranded RNA (dsRNA) are ... A host protein that recognizes invading viruses activates innate immunity defenses only when it senses both double-stranded RNA ... A host protein that recognizes invading viruses activates innate immunity defenses only when it senses both double-stranded RNA ... Cytosolic Viral Sensor RIG-I Is a 5'-Triphosphate-Dependent Translocase on Double-Stranded RNA ...
http://science.sciencemag.org/content/323/5917/1070
*  TLR3 as a Biomarker for the Therapeutic Efficacy of Double-stranded RNA in Breast Cancer | Cancer Research
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001;413:732-8. ... TLR3 as a Biomarker for the Therapeutic Efficacy of Double-stranded RNA in Breast Cancer. Bruno Salaun, Laurence Zitvogel, ... Here we show an example of this kind in which a drug [the double-stranded RNA (dsRNA) Poly (A:U)] can target its receptor TLR3 ... Adjuvant treatment with double-stranded RNA (dsRNA) was associated with a significant decrease in the risk of metastatic ...
http://cancerres.aacrjournals.org/content/71/5/1607
*  Quantification of Extracellular Double-stranded RNA Uptake and ...
Double-stranded RNA is a potent pathogen-associated molecular pattern (PAMP) produced as a by-product of viral replication and ... Keywords: Double-stranded RNA (双链RNA), Endosomes (内体), Lysosomes (溶酶体), Viruses (病毒), Poly(I:C) (聚(I:C)), TLR3 (TLR3), RIG-I ( ... Double-stranded RNA is a potent pathogen-associated molecular pattern (PAMP) produced as a by-product of viral replication and ... Double-stranded RNAs (dsRNAs) are a common by-product of viral replication and are potent activators of antiviral immunity via ...
https://bio-protocol.org/cn/e2890
*  Prkra - Interferon-inducible double-stranded RNA-dependent protein kinase activator A - Mus musculus (Mouse) - Prkra gene &...
Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and ... "RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling.". Ito T., Yang M., May W.S. ... "RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling.". Ito T., Yang M., May W.S. ... "RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling.". Ito T., Yang M., May W.S. ...
https://www.uniprot.org/uniprot/Q9WTX2
*  Inductive expression of double-stranded RNA (dsRNA) by | Open-i
Inductive expression of double-stranded RNA (dsRNA) by the Gal4/UAS system. Fly strains expressing Gal4 proteins in a ... genes-04-00646-f001: Inductive expression of double-stranded RNA (dsRNA) by the Gal4/UAS system. Fly strains expressing Gal4 ... genes-04-00646-f001: Inductive expression of double-stranded RNA (dsRNA) by the Gal4/UAS system. Fly strains expressing Gal4 ... and depends on sequence homology between double-stranded RNA (dsRNA) and target mRNA molecules. Numerous cell-based genome-wide ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3927573_genes-04-00646-g001&req=4
*  Double-stranded RNA pattern and partial sequence data indicate plant virus infection associated with the ringspot disease of...
Double-stranded RNA (dsRNA) has been extracted from tissue of European mountain ash trees ( Sorbus aucupariaL.) showing typical ... Double-stranded RNA (dsRNA) has been extracted from tissue of European mountain ash trees (Sorbus aucuparia L.) showing typical ... Double-stranded RNA pattern and partial sequence data indicate plant virus infection associated with the ringspot disease of ... particularly to the RNA-dependent RNA polymerase of members of the family Bunyaviridae, but without high similarity to a known ...
https://link.springer.com/article/10.1007%2Fs00705-004-0397-5
*  Post-transcriptional Gene Regulation by Double-stranded RNA-binding Proteins - Research Projects - Maquat Lab - University of...
URMC / Labs / Maquat Lab / Projects / Post-transcriptional Gene Regulation by Double-stranded RNA-binding Proteins ... We have found that STAU1, which is a double-stranded RNA binding protein, recruits the NMD factor UPF1 to certain mRNA 3'- ... Post-transcriptional Gene Regulation by Double-stranded RNA-binding Proteins Project Collaborators:. Dr. Manuel Ares University ... Thus, STAU1 binding to 3'UTR inverted Alu elements, like removal of these elements by alternative RNA 3'-end cleavage and ...
https://www.urmc.rochester.edu/labs/maquat/projects/post-transcriptional-gene-regulation-by-double-str.aspx
*  Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes...
RNA, Double-Stranded / metabolism. RNA-Binding Proteins / genetics, metabolism*. Ubiquitin-Protein Ligases / genetics, ... 0/Nerve Tissue Proteins; 0/RNA, Double-Stranded; 0/RNA-Binding Proteins; 0/stau2 protein, mouse; EC 6.3.2.19/TRIM32 protein, ... Here, we show that the double-stranded RNA-binding protein Stau2 is distributed asymmetrically during progenitor divisions in ... Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes ...
http://www.biomedsearch.com/nih/Asymmetric-Segregation-Double-Stranded-RNA/22902295.html
*  Double-Stranded RNA Binding by a Heterodimeric Complex of Murine Cytomegalovirus m142 and m143 Proteins | Journal of Virology
Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand ... of a vaccinia virus-encoded double-stranded RNA-binding protein that may be involved in inhibition of the double-stranded RNA- ... Double-Stranded RNA Binding by a Heterodimeric Complex of Murine Cytomegalovirus m142 and m143 Proteins. Stephanie J. Child, ... Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N- ...
https://jvi.asm.org/content/80/20/10173?ijkey=0a361afe55469a931c9455d3fe82109b34307984&keytype2=tf_ipsecsha
*  Double-Stranded RNA-Dependent Protein Kinase-Dependent Apoptosis Induction by a Novel Small Compound | Journal of Pharmacology...
ABBREVIATIONS: dsRNA, double-stranded RNA; PKR, double-stranded RNA-dependent protein kinase; MEF, mouse embryonic fibroblast; ... Double-Stranded RNA-Dependent Protein Kinase-Dependent Apoptosis Induction by a Novel Small Compound. Wenxian Hu, Wayne ... Double-Stranded RNA-Dependent Protein Kinase-Dependent Apoptosis Induction by a Novel Small Compound. Wenxian Hu, Wayne ... Double-Stranded RNA-Dependent Protein Kinase-Dependent Apoptosis Induction by a Novel Small Compound. Wenxian Hu, Wayne ...
http://jpet.aspetjournals.org/content/328/3/866
*  JAIRO | The dengue virus conceals double-stranded RNA in the intracellular membrane to escape from an interferon response.
The dengue virus conceals double-stranded RNA in the intracellular membrane to escape from an interferon response.. Double ... The dengue virus conceals double-stranded RNA in the intracellular membrane to escape from an interferon response. ... stranded-RNA concealingによるデングウイルスのI型IFN誘導回避機構. ...
http://jairo.nii.ac.jp/0013/00028589/en
*  Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide...
Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide ... Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide ... All samples contain 5 µM of single-stranded RNA (ssRNA1) and PNA in 130 µL. (A) Single-stranded RNA (ssRNA1), PNAs (P1, P2, P3 ... Gupta, P., Muse, O., Rozners, E. Recognition of double-stranded RNA by guanidine-modified peptide nucleic acids. Biochemistry. ...
https://www.jove.com/video/56221/sequence-specific-selective-recognition-double-stranded-rnas-over
*  Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer. - PubMed - NCBI
Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer.. Zhang Y1, He Q1, Hu Z1 ... Long noncoding RNA LINP1 regulates double strand DNA break repair in triple negative breast cancer ... Long noncoding RNA LINP1 regulates double strand DNA break repair in triple negative breast cancer ... Long noncoding RNA LINP1 regulates double strand DNA break repair in triple negative breast cancer ...
https://www.ncbi.nlm.nih.gov/pubmed/27111890