List of MeSH codes (G14) - Wikipedia
... terminal oligopyrimidine sequence MeSH G14.340.024.340.137.910 - untranslated regions MeSH G14.340.024.340.137.910.880 - 3 ... regulatory sequences, ribonucleic acid MeSH G14.080.689.687.249 - rna 3 polyadenylation signals MeSH G14.080.689.687.490 - rna ... terminal oligopyrimidine sequence MeSH G14.080.689.755 - silencer elements, transcriptional MeSH G14.080.689.810 - terminator ... terminal repeat sequences MeSH G14.080.708.850.400 - hiv long terminal repeat MeSH G14.080.708.850.400.400 - hiv enhancer MeSH ...
Tzeng, T. Y.<...
Gene Components | Profiles RNS
Terminal Oligopyrimidine Sequence. *RNA Splice Sites. *Untranslated Regions. publications Timeline , Most Recent ... A member of the polymerase beta nucleotidyltransferase superfamily is required for RNA interference in C. elegans. Curr Biol. ... A universal small molecule, inorganic phosphate, restricts the substrate specificity of Dicer-2 in small RNA biogenesis. Cell ... The parts of the gene sequence that carry out the different functions of the GENES. ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
Expressed Sequence Tags | Profiles RNS
Terminal Oligopyrimidine Sequence. *RNA Splice Sites. *Untranslated Regions. Below are MeSH descriptors whose meaning is more ... "Expressed Sequence Tags" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Expressed Sequence Tags" by people in this website by year, ... Development of an integrated transcript sequence database and a gene expression atlas for gene discovery and analysis in ...
RNA Splice Sites | Profiles RNS
Terminal Oligopyrimidine Sequence. *RNA Splice Sites. *Untranslated Regions. *Regulatory Sequences, Ribonucleic Acid ... Nucleotide sequences located at the ends of EXONS and recognized in pre-messenger RNA by SPLICEOSOMES. They are joined during ... Predicting RNA splicing from DNA sequence using Pangolin. Genome Biol. 2022 04 21; 23(1):103. ... "RNA Splice Sites" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ...
Plus it
RNA-immunoprecipitation sequencing (RIP-Seq) of the two eIF4A paralogs revealed that eIF4A1 preferentially binds to mRNAs ... containing terminal oligopyrimidine (TOP) motifs, whose translation is rapidly repressed upon mTOR inhibition. This biased ... 1RNA Systems Biochemistry Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama 351-0198, Japan ... 1RNA Systems Biochemistry Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama 351-0198, Japan ...
Búsqueda | BVS Bolivia
... terminal oligopyrimidine (5TOP) sequence. Members of the La-related protein 1 (LARP1) family control 5TOP expression through ... RNA sequencing analysis of Rpl13a-/- morulae revealed widespread alterations in gene expression, including but not limited to ... METHODS: We performed single-cell RNA sequencing (scRNA-seq) to analyze the differences of immunocytes in immunoresponse and ... and C-terminal regions. In particular, the positive electrostatic surface at the C-terminal of eryngitin 4 is due to the ...
Alu elements. Medical search
MolecularTerminal Repeat SequencesRNA, MessengerRestriction MappingChromosome MappingBinding SitesGene Rearrangement ... terminal oligopyrimidine tract mRNA family. Most of the activated transcripts represented uncharacterized genes. The most ... TERMINAL REPEAT SEQUENCES flank both ends of another sequence, for example, the long terminal repeats (LTRs) on RETROVIRUSES. ... Alu Repetitive Sequence. Alu Repetitive Sequences. Alu- ... Family, Alu Repetitive Sequence, Alu Repetitive Sequences, Alu ...
September 2019 - Engineering a Therapeutic Lectin by Uncoupling Mitogenicity
Dual\luciferase assays (cloning and co\transfection) Short sequences from your 3UTR of and mutated (mut)\short 3 UTR and and ... Cells had been collected 48?h post\infection for cell and RNA bioenergetics assays. 2.8. Set of antibodies for traditional ... uORF-RNAs) encoding two Mouse monoclonal to CD81.COB81 reacts with the CD81, a target for anti-proliferative antigen (TAPA-1) ... and they are classified into several genera based on their DNA sequences. The presence of HPV E6 and E7 oncoproteins in the ...
LncRNA Gas5 acts as a ceRNA to regulate PTEN expression by sponging miR-222-3p in papillary thyroid carcinoma | Oncotarget
... terminal oligopyrimidine gene family reveals common features of snoRNA host genes. Mol Cell Biol. 1998; 18:6897-909. ... RNA extraction and qRT-PCR analyses. Total RNA extraction was conducted using a TRIzol reagent kit (Life Technologies, Inc., ... Primer sequences were as follows: Gas5 forward 5′-AGCTGGAAGTTGAAATGG-3′ and reverse 5′-CAAGCCGACTCTCCATA C-3′, PTEN forward 5′- ... Shi X, Sun M, Liu H, Yao Y, Kong R, Chen F, Song Y. A critical role for the long non-coding RNA GAS5 in proliferation and ...
Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma Cells | BMC...
The 5-Fu treatment nearly abolishes transcription of hTERT (the major component of telomerase) mRNA. Treating SMMC-7721 cells ... 5-Fu and rapamycin were synergistic in regards to down-regulation of telomerase activity in hepatocarcinoma cells. These ... Treating SMMC-7721 cells with 5-Fu leads to apoptosis of the cells, and reduction in telomerase activity, as well as a dramatic ... 5-Fu). We detected apoptosis of hepatocarcinoma cells by TUNEL assay. Telomerase activity, hTERT transcription level and p- p70 ...
Phospho-S6 Ribosomal Protein (Ser240/244) (D68F8) XP® Rabbit mAb (Alexa Fluor® 488 Conjugate) | Cell Signaling Technology
The antigen sequence used to produce this antibody shares 100% sequence homology with the species listed here, but reactivity ... of S6 ribosomal protein correlates with an increase in translation of mRNA transcripts that contain an oligopyrimidine tract in ... carboxy-terminal region of S6 protein (4,5). ... Species predicted to react based on 100% sequence homology: ... Because recombinant antibody production involves sequencing the antibody light and heavy chains, it is a highly controlled and ...
Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in...
Terminal Oligopyrimidine Sequence Actions. * Search in PubMed * Search in MeSH ... RNA 5 ... Results: Sequence comparison and 5 RACE analysis of the 5 ... Rapamycin induces binding activity to the terminal oligopyrimidine tract of ribosomal protein mRNA in rats. Kakegawa T, Ito M, ... Published sequence data suggest the 5 untranslated regions of K6a and K6b mRNAs contain 5 TOP motifs and therefore may be ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
MeSH Browser
Terminal Oligopyrimidine Sequence [G02.111.570.080.689.687.275] * RNA Splice Sites [G02.111.570.080.689.687.490] ... Terminal Oligopyrimidine Sequence Preferred Concept UI. M0416549. Scope Note. A regulatory sequence found in the 5 terminal ... Terminal Oligopyrimidine Sequence Preferred Term Term UI T484520. Date03/05/2002. LexicalTag ACX. ThesaurusID NLM (2003). ... Terminal Oligopyrimidine Regulatory Sequence Term UI T484521. Date03/05/2002. LexicalTag ACX. ThesaurusID NLM (2003). ...
MeSH Browser
Terminal Oligopyrimidine Sequence [G02.111.570.080.689.687.275] * RNA Splice Sites [G02.111.570.080.689.687.490] ... Terminal Oligopyrimidine Sequence Preferred Concept UI. M0416549. Scope Note. A regulatory sequence found in the 5 terminal ... Terminal Oligopyrimidine Sequence Preferred Term Term UI T484520. Date03/05/2002. LexicalTag ACX. ThesaurusID NLM (2003). ... Terminal Oligopyrimidine Regulatory Sequence Term UI T484521. Date03/05/2002. LexicalTag ACX. ThesaurusID NLM (2003). ...
DeCS
Terminal Oligopyrimidine Sequence [G02.111.570.080.689.687.275] RNA 5 Terminal Oligopyrimidine Sequence ... Terminal Oligopyrimidine Sequence - Preferred Concept UI. M0416549. Scope note. A regulatory sequence found in the 5 terminal ... Terminal Oligopyrimidine Regulatory Sequence Sequence, 5 TOP Sequences, 5 TOP 5 TOP mRNA - Related but not broader or ... Terminal Oligopyrimidine Regulatory Sequence. Sequence, 5 TOP. Sequences, 5 TOP. Tree number(s):. G02.111.570.080.689.687.275 ...
High-throughput translational profiling with riboPLATE-seq | Scientific Reports
We compare RA to its analogue in ribosome profiling and RNA sequencing, translation efficiency, and demonstrate both the ... but we lack a systems-level picture of how signaling molecules and RNA binding proteins interact with the translational ... cap and immediate downstream C/T-rich sequences, known as terminal oligopyrimidine (TOP) motifs, which prevents translation of ... f) The corresponding plot to e derived from ribosome profiling and RNA sequencing data of TE and RNA-seq transcript abundance ...
MESH TREE NUMBER CHANGES - 2013 MeSH. December 5, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Disulfonic Acid Disodium Salt D2.755.166.210 D2.455.426.559.389.657.166.210 2,3-Diphosphoglycerate D2.705.196.175 D2.705. ... 400.140.175 2,4,5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4- ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
MESH TREE NUMBER CHANGES - 2013 MeSH. August 27, 2012
Terminal Oligopyrimidine Sequence G2.111.570.80.689.687.500 G2.111.570.80.689.687.275 G5.360.80.689.687.500 G5.360.80.689. ... 687.275 RNA Splice Sites G5.360.340.24.340.137.780 G5.360.340.24.340.137.800 Saint Kitts and Nevis Z1.639.880.787 Saint Lucia ... 5-Trichlorophenoxyacetic Acid D2.241.511.316.881 D2.241.81.18.386.682.800 D2.241.511.316.682.800 2,4-Dichlorophenoxyacetic Acid ... D2.241.81.18.110.80 2-Hydroxy-5-nitrobenzyl Bromide D2.755.566.400 D2.455.426.559.389.657.566.400 2-Methyl-4- ...
Pesquisa | Prevenção e Controle de Câncer
... whole-exome sequencing, whole-genome sequencing, and whole-transcriptome sequencing or RNA sequencing. In patients with myeloid ... terminal oligopyrimidine tracts (TOP) that encode protein machinery components and are frequently altered in cancer4. ... RNA de Transferência/genética , RNA de Transferência/metabolismo , Proteínas de Ligação a RNA/genética ... Here, we develop a tailored bioinformatic pipeline to integrate public and proprietary single-cell RNA sequencing (scRNA-seq) ...
A specific eIF4A paralog facilitates LARP1-mediated translation repression during mTORC1 inhibition | bioRxiv
RNA immunoprecipitation-sequencing (RIP-Seq) revealed that the two eIF4A paralogs have different properties in RNA binding and ... represses terminal oligopyrimidine (TOP) mRNA translation downstream of mTOR complex 1 (mTORC1). J. Biol. Chem. 290, 15996- ... For RNA-Seq, 1 µg of RNA extracted from the same lysate sample with TRIzol LS and a Direct-zol RNA Microprep Kit was used for ... we set out RNA immunoprecipitation-sequencing (RIP-Seq) from RNA complexed with eIF4A1 and eIF4A2 in human embryonic kidney ( ...
The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape | Cell Death &...
... but little is known about the detailed relationships between RNA helicase function and the malignant phenotype in solid ... and for mRNAs with G/C-rich 5′UTRs with potential to form G-quadruplexes and with 3′UTRs containing microRNA target sites. ... DeXD/H-box helicases are ubiquitous molecular motors that are required for the majority of cellular processes that involve RNA ... UTRs containing terminal oligopyrimidine tracts (TOPs) with little potential for structure formation. ...
Larp Society | the LARP society (LARPSOC) comprises scientists from many disciplines with a shared interest in the study of La...
... terminal oligo-pyrimidine sequence (5TOP) but did not affect the stability of their corresponding pre-mRNAs. They observed no ... the authors concluded that the interaction was RNA-independent as it was conserved after enzymatic RNA digestion. In the ... terminal oligo-pyrimidine (5TOP)-bearing mRNAs by interacting with the 3 terminus of their poly-A tails. ... A link to the manuscript: Muniz, L., Egloff, S. and Kiss, T. (2013) RNA elements directing in vivo assembly of the 7SK/MePCE/ ...
Biomarkers Search
Correlated sequence signatures are present within the genomic 5UTR RNA and NSP1 protein in coronaviruses.. Sosnowski P; Tidu A ... terminal oligopyrimidine tracts preferentially escape global suppression of translation by the SARS-CoV-2 Nsp1 protein.. Rao S ... Cap-independent translation and a precisely located RNA sequence enable SARS-CoV-2 to control host translation and escape anti- ... The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral ...
Search | WHO COVID-19 Research Database
... terminal oligopyrimidine tracts preferentially escape global suppression of translation by the SARS-CoV-2 Nsp1 protein. ... Unification of sequence and structure data is an important task in structural biology. Here, we present the Sequence Similarity ... and ddhCTP suppressed the replication of several other CoVs of different genera through inhibition of the RNA-dependent RNA ... terminal oligo-pyrimidine (TOP) tracts among preferentially translated genes. Using reporter assays, we validated that 5 UTRs ...
Anti-Phospho-RPS6: Rabbit Ribosomal S6 Protein, Phospho-Ser235/Ser236 Antibody | sputnic-group.ru : Cell Applications
Peptide sequence around phosphorylation site of serine 235 (R-L-S(p)-S-L), according to the protein RPS6. ... Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. Ribosomal protein S6 ... These particular mRNA transcripts (5TOP) contain an oligopyrimidine tract in their 5 untranslated regions and encode ... with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a ...
Gladyshev Lab
... terminal oligopyrimidine (5′-TOP) transcripts encoding protein synthesis and ribosome biogenesis machinery and regulated by the ... 2020) N6-adenosine methylation of ribosomal RNA affects lipid oxidation and stress resistance. Sci Adv. 6(17), eaaz4370. ... Transcriptome sequencing, ribosome profiling, whole proteome, and phosphoproteome analyses show that eIF3m deficiency leads to ... including small molecule inhibitors and read-through inducing sequences, on the translation termination rate. With CTELS, we ...
Internal Ribosome Entry in the Coding Region of Murine Hepatitis Virus mRNA 5 | Microbiology Society
Thus, in the context of the MHV mRNA 5 unique region, the initiation of protein synthesis on ORF 5b can occur independently of ... More importantly, the expression of ORF 5b, but not ORF 5a, is maintained in a trieistronic mRNA containing an additional 5′- ... mRNA 5 has two open reading frames, ORF 5a and ORF 5b, that encode small proteins of unknown function. In the experiments ... ribosomes that enter from the 5′ end of the mRNA. We conclude that the translation of ORF 5b is mediated by the internal entry ...
COVID-19 Research Registry | Basic Virology | ASM.org
Cap-independent translation and a precisely located RNA sequence enable SARS-CoV-2 to control host translation and escape anti- ... terminal oligopyrimidine tracts preferentially escape global suppression of translation by the SARS-CoV-2 NSP1 protein. ... A structurally conserved RNA element within SARS-CoV-2 ORF1a RNA and S mRNA regulates translation in response to viral S ... High-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling. ...
Identification of gene interactions associated with disease from gene expression data using synergy networks | BMC Systems...
... terminal oligopyrimidine tract (TOP) used for translational control. It has been proposed that oncogenic transformation by Akt ... collection of high-quality standardized gene expression data is not expensive compared with other efforts such as sequencing, ... RNA Biol. 2004, 1: 89-94.. Article CAS PubMed Google Scholar *. Orino K, Lehman L, Tsuji Y, Ayaki H, Torti SV, Torti FM: ... Figure 5. Scatter plots of top-ranked gene pairs invalidation data set. On the left is the original data set, and on the right ...
Glutamate (EAAT) Transporters
RNA can be connected with polysomes.… Continue reading Determination of the 5 terminus from the RNA revealed that ... and in silico studies revealed that NCT-50 downregulated Hsp90 function by interacting with the C-terminal ATP-binding pocket ... The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopoxviruses ... Determination of the 5 terminus from the RNA revealed that transcription from the gene begins having a C residue accompanied by ...