The PI will probe the RNA structure in the 5-UTR of the dksA mRNA and carefully examine its role in translation control. The ... untranslated region (5-UTR). One aim of this project is to investigate how dksA is transcriptionally controlled under various ... DksA differs from most bacterial gene regulators in that it functions by binding directly to the RNA polymerase enzyme (the ... Preliminary work indicated that the dksA gene is regulated at the level of transcription (i.e RNA synthesis). The regulation ...